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Clinical Evaluation of Three KRS Families and Cellular Analysis of Distinct ATP13A2 Mutations Reveal Different Levels of Iron Accumulation

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pmc.ncbi.nlm.nih.gov/articles/PMC13054781/
Mar 2026
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Targeting the energy metabolism of melanoma cells: FX-11 acts as a mitochondrial uncoupler

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1. scibot 26 Mar 2026
  
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sciencedirect.com/science/article/pii/S0014299926002827
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Spastin Is Required to Prevent SPAST-Related Demyelination

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  DOI: 10.1111/jnc.70407
  
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onlinelibrary.wiley.com/doi/full/10.1111/jnc.70407
Feb 2026
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Large-scale mapping of environmental-genetic interactions illustrates the dynamic nature of cell-cycle and DNA repair regulation

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Glucocorticoid-dependence and independence of the circadian liver transcriptome

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  DOI: 10.1038/s44323-025-00068-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12864027/
Jan 2026
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Myomaker and ether lipids cooperate to promote fusion-competent membrane states

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  DOI: 10.1016/j.celrep.2025.116900
  
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sciencedirect.com/science/article/pii/S2211124725016729
Nov 2025
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Molecular basis of autoimmune disease protection by MDA5 variants

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pmc.ncbi.nlm.nih.gov/articles/PMC7618376/
Oct 2025
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Tuning insulin receptor signaling using de novo-designed agonists

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sciencedirect.com/science/article/pii/S1097276525007804
Jul 2025
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Parkinson’s disease microglia induce endogenous α-synuclein pathology in patient-specific midbrain organoids

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  DOI: 10.1101/2025.07.01.662685
  
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biorxiv.org/content/10.1101/2025.07.01.662685v1
Jun 2025
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52.53.155.43/05d4c62ce2701e8f0182ba5b4481beae93cc006f/PDF-html.html
May 2025
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Cross-species tropism of AAV.CPP.16 in the respiratory tract and its gene therapies against pulmonary fibrosis and viral infection

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sciencedirect.com/science/article/pii/S2666379125002174
Apr 2025
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52.53.155.43/d92b011119470b2ed58da6e2cdd0541e039e2530/PDF-html.html
Mar 2025
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Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinoma

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1. scibot 29 Mar 2025
  
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The actin and microtubule network regulator WHAMM is identified as a key kidney disease risk gene

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sciencedirect.com/science/article/pii/S2211124725002335
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52.53.155.43/6a1077851a93128037200ab8bc35f1d4060f0db6/PDF-html.html
Jan 2025
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The human zinc-binding cysteine proteome

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.cell.2024.11.025
  
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sciencedirect.com/science/article/pii/S0092867424013412
Nov 2024
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Granulins rescue inflammation, lysosome dysfunction, lipofuscin, and neuropathology in a mouse model of progranulin deficiency

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sciencedirect.com/science/article/pii/S2211124724013366
Sep 2024
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CD14 is a decision-maker between Fas-mediated death and inflammation

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sciencedirect.com/science/article/pii/S2211124724010362
Aug 2024
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Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection

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Acetate enables metabolic fitness and cognitive performance during sleep disruption

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sciencedirect.com/science/article/pii/S1550413124002900
Feb 2024
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Crystal structure and biochemical activity of the macrodomain from rubella virus p150

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ncbi.nlm.nih.gov/pmc/articles/PMC10878246/
Jan 2024
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Atrial natriuretic peptide signaling co-regulates lipid metabolism and ventricular conduction system gene expression in the embryonic heart

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ncbi.nlm.nih.gov/pmc/articles/PMC10792247/
Dec 2023
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SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation

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Oct 2023
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Parkinson’s-linked LRRK2-G2019S derails AMPAR trafficking, mobility and composition in striatum with cell-type and subunit specificity

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  DOI: 10.1101/2023.10.13.562231
  
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biorxiv.org/content/10.1101/2023.10.13.562231v1
Sep 2023
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Nectin-3 and shed forms of CSPG4 can serve as epithelial cell receptors for Clostridioides difficile TcdB

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  DOI: 10.1128/mbio.01857-23
  
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journals.asm.org/doi/10.1128/mbio.01857-23
Aug 2023
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The Evaluation of Rac1 Signaling as a Potential Therapeutic Target of Alzheimer’s Disease

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  DOI: 10.3390/ijms241511880
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10418761/
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Identification of lysosomal genes associated with prognosis in lung adenocarcinoma

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  DOI: 10.21037/tlcr-23-14
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10413022/
Jul 2023
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Super-resolution imaging unveils the self-replication of tau aggregates upon seeding

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Jun 2023
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METTL14 is decreased and regulates m6A modification of α-synuclein in Parkinson's disease

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  DOI: 10.1111/jnc.15882
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15882
Jan 2023
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Exosome-based bone-targeting drug delivery alleviates impaired osteoblastic bone formation and bone loss in inflammatory bowel diseases

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  DOI: 10.1016/j.xcrm.2022.100881
  
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sciencedirect.com/science/article/pii/S2666379122004451
Dec 2022
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Structure and functional mapping of the KRAB-KAP1 repressor complex

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  DOI: 10.15252/embj.2022111179
  
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embopress.org/doi/10.15252/embj.2022111179
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AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer

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  DOI: 10.1007/s00018-022-04638-y
  
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link.springer.com/article/10.1007/s00018-022-04638-y
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Chaperone requirements for de novo folding of Saccharomyces cerevisiae septins

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  DOI: 10.1091/mbc.E22-07-0262
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9635297/
Sep 2022
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CRISPR-Cas9 screen in human embryonic stem cells to identify genes required for neural differentiation

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  DOI: 10.1016/j.xpro.2022.101682
  
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STAG2 promotes the myelination transcriptional program in oligodendrocytes

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1. scibot 08 Sep 2022
  
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  DOI: 10.7554/eLife.77848
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9439679/
May 2022
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A bioactive phlebovirus-like envelope protein in a hookworm endogenous virus

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1. scibot 28 May 2022
  
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Development of novel aptamer-based targeted chemotherapy for bladder cancer

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Human cerebral organoids reveal progenitor pathology in EML1-linked cortical malformation

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Kidney organoids recapitulate human basement membrane assembly in health and disease

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TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling

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The ESCRT machinery counteracts Nesprin-2G-mediated mechanical forces during nuclear envelope repair

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Synthesis and structure-activity relationships of targeted protein degraders for the understudied kinase NEK9

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Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation

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Selective functional inhibition of a tumor-derived p53 mutant by cytosolic chaperones identified using split-YFP in budding yeast

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Untitled document

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Parkinson's Disease-Linked LRRK2-G2019S Mutation Alters Synaptic Plasticity and Promotes Resilience to Chronic Social Stress in Young Adulthood

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Inhibition of checkpoint kinase 1 following gemcitabine-mediated S phase arrest results in CDC7- and CDK2-dependent replication catastrophe

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Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38

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Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38

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Human Condensin I and II Drive Extensive ATP-Dependent Compaction of Nucleosome-Bound DNA

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FEBS Press

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Cryo-EM structure of VASH1-SVBP bound to microtubules

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Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication

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Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation

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Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma

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SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst

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High‐potassium preconditioning enhances tolerance to focal cerebral ischemia‐reperfusion injury through anti‐apoptotic effects in male rats

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Local Fatty Acid Channeling into Phospholipid Synthesis Drives Phagophore Expansion during Autophagy

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An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis

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Untitled document

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Amniotic Fluid Exosome Proteomic Profile Exhibits Unique Pathways of Term and Preterm Labor

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Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone

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Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion

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