192 Matching Annotations
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    Pre-clinical Modeling of Navtemadlin Pharmacokinetics, Pharmacodynamics, and Efficacy in IDH-wildtype Glioblastoma
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    NF1 Loss Promotes EGFR Activation and Confers Sensitivity to EGFR Inhibition in NF1 Mutant Melanoma
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  4. Aug 2025
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    Design of multi-target peptide modulators for protein chaperone networks
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    Tumor-resident probiotic Clostridium butyricum improves aPD-1 efficacy in colorectal cancer models by inhibiting IL-6-mediated immunosuppression
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    A pan-KRAS inhibitor and its derived degrader elicit multifaceted anti-tumor efficacy in KRAS-driven cancers
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  8. Jul 2025
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    IFNγ augments TKI efficacy by alleviating protein unfolding stress to promote GSDME-mediated pyroptosis in hepatocellular carcinoma
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  12. Jun 2025
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    Splicing Shift of RAC1 Accelerates Tumorigenesis and Defines a Potent Therapeutic Target in Lung Cancer
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  18. May 2025
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    Suppressing proteasome activity enhances sensitivity to actinomycin D in diffuse anaplastic Wilms tumor
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  35. Jan 2025
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  38. Dec 2024
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  51. Jul 2024
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  57. Jun 2024
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  63. May 2024
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  70. Apr 2024
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  75. Mar 2024
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  78. Feb 2024
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    Identification of a First-in-Class Small Molecule Inhibitor of the eIF4E-RBM38 Complex that Enhances wild-type p53 Protein Translation for Tumor Growth Suppression
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  83. Dec 2023
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  89. Nov 2023
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    Entinostat Enhances the Efficacy of Chemotherapy in Small Cell Lung Cancer Through S-phase Arrest and Decreased Base Excision Repair
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  92. Oct 2023
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    High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma
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  95. Sep 2023
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    Microenvironmental stiffness induces metabolic reprogramming in glioblastoma
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    RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations
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  99. Aug 2023
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    Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
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    Discovery of a pyrrole-pyridinimidazole derivative as novel SIRT6 inhibitor for sensitizing pancreatic cancer to gemcitabine
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    Targeting Bcl-xL is a potential therapeutic strategy for extranodal NK/T cell lymphoma
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  105. Jul 2023
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    Dexamethasone affects human fetal adrenal steroidogenesis and subsequent ACTH response in an ex vivo culture model
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  230. Nov 2018
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