32 Matching Annotations
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    Profound synthetic lethality between SMARCAL1 and FANCM
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    1. scibot 17 Nov 2024
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    sciencedirect.com/science/article/pii/S1097276524008566
  3. Aug 2024
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    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
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    sciencedirect.com/science/article/pii/S1097276524006609
  5. Jul 2024
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    Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton
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    sciencedirect.com/science/article/pii/S2211124724008398
  7. May 2024
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    Molecular subtypes of neuroendocrine carcinomas: A cross-tissue classification framework based on five transcriptional regulators
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  9. Apr 2024
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    BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response
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    sciencedirect.com/science/article/pii/S1097276524002211
  11. Mar 2024
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    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
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    2. scibot 08 Mar 2024
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    Targeting up-regulated cIAP2 in SOX10-deficient drug tolerant melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10527992/
  14. Feb 2024
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    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
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    sciencedirect.com/science/article/pii/S2211124724001736
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    RNF4 prevents genomic instability caused by chronic DNA under-replication
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    1. scibot 15 Feb 2024
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    sciencedirect.com/science/article/pii/S1568786424000223
  17. Dec 2023
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    FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination
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    sciencedirect.com/science/article/pii/S2211124723015358
  19. Oct 2023
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    DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C
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  21. Aug 2023
  22. 52.53.155.43 52.53.155.43
    mct-23-0025 (1)-html.html
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    C1orf112 teams up with FIGNL1 to facilitate RAD51 filament disassembly and DNA interstrand cross-link repair
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  24. Jun 2023
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
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    Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity
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    sciencedirect.com/science/article/pii/S0092867423005329
  27. Apr 2023
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    ERCC6L2 mitigates replication stress and promotes centromere stability
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      DOI: 10.1016/j.celrep.2023.112329

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    sciencedirect.com/science/article/pii/S2211124723003406
  29. Feb 2023
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    RIF1 suppresses the formation of single-stranded ultrafine anaphase bridges via protein phosphatase 1
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    sciencedirect.com/science/article/pii/S2211124723000438
  31. Jan 2023
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    The human placenta shapes the phenotype of decidual macrophages
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    sciencedirect.com/science/article/pii/S2211124722018812
  33. Sep 2022
  34. www.nature.com www.nature.com
    A RUNX-targeted gene switch-off approach modulates the BIRC5/PIF1-p21 pathway and reduces glioblastoma growth in mice
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      DOI: 10.1038/s42003-022-03917-5

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    nature.com/articles/s42003-022-03917-5
  35. May 2022
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    A PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination
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  37. Mar 2022
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    CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities
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    sciencedirect.com/science/article/pii/S2211124722001759
  39. Nov 2021
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    Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulation
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    sciencedirect.com/science/article/pii/S1535610821005596
  41. Sep 2021
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    REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps
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    sciencedirect.com/science/article/pii/S1097276521006833
  43. Aug 2021
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    Oestrogen signalling drives ciliogenesis in human endometrial organoids
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      DOI: 10.1210/en.2019-00314

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    academic.oup.com/endo/article/160/10/2282/5530205
  45. Apr 2021
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    Functional interrogation of DNA damage response variants with base editing screens
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      DOI: 10.1016/j.cell.2021.01.041

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    sciencedirect.com/science/article/pii/S0092867421000842
  47. Sep 2020
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    Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase
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      DOI: 10.1016/j.celrep.2020.107533

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    sciencedirect.com/science/article/pii/S2211124720304332
  49. Jan 2020
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    C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex
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      DOI: 10.1016/j.molcel.2019.06.023

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    sciencedirect.com/science/article/pii/S1097276519304794
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    Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint
    1
    1. scibot 13 Jan 2020
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      DOI: 10.7554/eLife.44353

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    ncbi.nlm.nih.gov/pmc/articles/PMC6561707/
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    Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops
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      DOI: 10.1016/j.molcel.2019.10.026

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    sciencedirect.com/science/article/pii/S1097276519308044
  53. Nov 2017
  54. www.sciencedirect.com www.sciencedirect.com
    RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis
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    sciencedirect.com/science/article/pii/S1097276517303192