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CLIM-TIME identifies metastatic microenvironment modulators for T cell therapy response

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1. scibot 12 Feb 2026
  
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  DOI: 10.1016/j.cell.2025.12.042
  
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sciencedirect.com/science/article/pii/S0092867425014916
Feb 2026
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Indigenous gut microbes modulate neural cell state and neurodegenerative disease susceptibility

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1. scibot 05 Feb 2026
  
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  DOI: 10.1016/j.cels.2025.101481
  
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sciencedirect.com/science/article/pii/S240547122500314X
Jan 2026
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Innate lymphoid cells activated by the cytokine TL1A link colitis to emergency granulopoiesis and the recruitment of tumor-promoting neutrophils

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1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.immuni.2025.12.008
  
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sciencedirect.com/science/article/pii/S1074761325005643
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CRISPR screens in the context of immune selection identify CHD1 and MAP3K7 as mediators of cancer immunotherapy resistance

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1. scibot 22 Jan 2026
  
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  DOI: 10.1016/j.xcrm.2025.102565
  
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sciencedirect.com/science/article/pii/S266637912500638X
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Depletion of myeloid cells in AG129 mice reduces the infection-mediated oxidative stress and restrains dengue virus-induced thymic atrophy

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1. scibot 16 Jan 2026
  
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  DOI: 10.1186/s12964-025-02572-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12797958/
www.biorxiv.org www.biorxiv.org

Second-order regulation: IFN-γ suppresses IL-17A-mediated neutrophilic inflammation

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1. scibot 15 Jan 2026
  
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  RRID:AB_10805519
  
  DOI: 10.64898/2026.01.05.697792
  
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biorxiv.org/content/10.64898/2026.01.05.697792v1
May 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225009071-main-html.html

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.isci.2025.112646
  
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52.53.155.43/15bb5c34ed2863ce5982ef48bb82b2f762524a3e/1-s2.0-S2589004225009071-main-html.html
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Understanding and reversing mammary tumor-driven reprogramming of myelopoiesis to reduce metastatic spread

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.ccell.2025.04.007
  
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sciencedirect.com/science/article/pii/S1535610825001667
Apr 2025
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Reprogramming liver metastasis-associated macrophages toward an anti-tumoral phenotype through enforced miR-342 expression

1
1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.celrep.2025.115592
  
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sciencedirect.com/science/article/pii/S2211124725003638
www.cell.com www.cell.com

Acute exposure to high-fat diet impairs ILC3 functions and gut homeostasis

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1. scibot 15 Apr 2025
  
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  RRID:AB_10805519
  
  DOI: 10.1016/j.immuni.2025.03.017
  
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cell.com/immunity/fulltext/S1074-7613(25)00136-0
Feb 2025
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GPNMB and ATP6V1A interact to mediate microglia phagocytosis of multiple types of pathological particles

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1. scibot 25 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115343
  
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sciencedirect.com/science/article/pii/S2211124725001147
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Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate onset of allergic airway neutrophilic disease

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1. scibot 20 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115294
  
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sciencedirect.com/science/article/pii/S2211124725000658
Nov 2024
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Differential contributions of fetal mononuclear phagocytes to Zika virus neuroinvasion versus neuroprotection during congenital infection

1
1. scibot 14 Nov 2024
  
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  RRID:AB_10805519
  
  DOI: 10.1016/j.cell.2024.10.028
  
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sciencedirect.com/science/article/pii/S0092867424012108
May 2024
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Tuft cell acetylcholine is released into the gut lumen to promote anti-helminth immunity

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1. scibot 14 May 2024
  
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  RRID:AB_10805519
  
  DOI: 10.1016/j.immuni.2024.04.018
  
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sciencedirect.com/science/article/pii/S1074761324002231
Apr 2024
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The ecotin-like peptidase inhibitor of Trypanosoma cruzi prevents TMPRSS2-PAR2-TLR4 crosstalk downmodulating infection and inflammation

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1. scibot 11 Apr 2024
  
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  RRID:AB_10805519
  
  DOI: 10.1096/fj.202302091RR
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202302091RR
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Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection

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1. scibot 11 Apr 2024
  
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  RRID:AB_10805519
  
  DOI: 10.1016/j.celrep.2024.114007
  
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sciencedirect.com/science/article/pii/S2211124724003358
Jan 2024
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Fc-fused IL-7 provides broad antiviral effects against respiratory virus infections through IL-17A-producing pulmonary innate-like T cells

1
1. scibot 21 Jan 2024
  
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  RRID:AB_10805519
  
  DOI: 10.1016/j.xcrm.2023.101362
  
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sciencedirect.com/science/article/pii/S2666379123005797
Jul 2023
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks

1
1. scibot 21 Jul 2023
  
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  RRID:AB_10805519
  
  DOI: 10.1016/j.immuni.2023.06.020
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10433941/
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LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer

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1. scibot 13 Jul 2023
  
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  DOI: 10.1016/j.devcel.2023.06.006
  
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sciencedirect.com/science/article/pii/S1534580723003040
May 2023
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Integrating multiplex immunofluorescent and mass spectrometry imaging to map myeloid heterogeneity in its metabolic and cellular context

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1. scibot 05 May 2023
  
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  DOI: 10.1016/j.cmet.2022.06.012
  
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sciencedirect.com/science/article/pii/S1550413122002327
Jan 2023
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Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development

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1. scibot 28 Jan 2023
  
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  DOI: 10.1016/j.immuni.2022.11.013
  
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sciencedirect.com/science/article/pii/S1074761322006033
Dec 2022
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IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer

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1. scibot 17 Dec 2022
  
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  DOI: 10.1016/j.ccell.2022.11.014
  
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sciencedirect.com/science/article/pii/S153561082200561X
Jun 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Monocarboxylate transporter 1 deficiency impacts CD8+ T lymphocytes proliferation and recruitment to adipose tissue during obesity

1
1. scibot 15 Jun 2022
  
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  RRID:AB_10805519
  
  DOI: 10.1016/j.isci.2022.104435
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9189020/
Feb 2022
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Mucosal fungi promote gut barrier function and social behavior via Type 17 immunity

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1. scibot 18 Feb 2022
  
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  DOI: 10.1016/j.cell.2022.01.017
  
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sciencedirect.com/science/article/pii/S0092867422000757
Jan 2022
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Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches

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1. scibot 12 Jan 2022
  
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  RRID:AB_10805519
  
  DOI: 10.1016/j.cell.2021.12.018
  
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sciencedirect.com/science/article/pii/S0092867421014811
Dec 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting myeloid-derived suppressor cells to attenuate vasculogenic mimicry and synergistically enhance the anti-tumor effect of PD-1 inhibitor

1
1. scibot 01 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103392
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8605339/
Nov 2021
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Expanded renal lymphatics improve recovery following kidney injury

1
1. scibot 23 Nov 2021
  
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  AB_10805519
  
  DOI: 10.14814/phy2.15094
  
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physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.15094
Sep 2021
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A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism

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1. scibot 22 Sep 2021
  
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  DOI: 10.1016/j.celrep.2021.109748
  
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sciencedirect.com/science/article/pii/S221112472101202X
Aug 2021
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Environmental enteric dysfunction induces regulatory T cells that inhibit local CD4+ T cell responses and impair oral vaccine efficacy

1
1. scibot 15 Aug 2021
  
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  DOI: 10.1016/j.immuni.2021.07.005
  
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sciencedirect.com/science/article/pii/S1074761321002910
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Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT

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1. scibot 10 Aug 2021
  
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  DOI: 10.1016/j.immuni.2018.11.010
  
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sciencedirect.com/science/article/pii/S1074761318304928
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Untitled document

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1. scibot 09 Aug 2021
  
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  DOI: 10.1016/j.chom.2018.11.003
  
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sciencedirect.com/science/article/pii/S1931312818305602
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Response to Fungal Dysbiosis by Gut Resident CX3CR1+ Mononuclear Phagocytes Aggravates Allergic Airway Disease

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1. scibot 27 Jul 2021
  
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  DOI: 10.1016/j.chom.2018.11.003
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6292739/
Jan 2021
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Disrupted Iron Metabolism and Mortality during Co-infection with Malaria and an Intestinal Gram-Negative Extracellular Pathogen

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1. scibot 22 Jan 2021
  
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  RRID:AB_10805519
  
  DOI: 10.1016/j.celrep.2020.108613
  
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  Curator: @Naa003
  
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  RRID:AB_10805519 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124720316028
Oct 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dendritic Cells and Microglia Have Non-redundant Functions in the Inflamed Brain with Protective Effects of Type 1 cDCs

1
1. scibot 27 Oct 2020
  
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  DOI: 10.1016/j.celrep.2020.108291
  
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  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7578563/
Sep 2020
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Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver

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1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.immuni.2020.08.004
  
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Mouse Ovarian Cancer Models Recapitulate the Human Tumor Microenvironment and Patient Response to Treatment

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1. scibot 16 Sep 2020
  
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  DOI: 10.1016/j.celrep.2019.12.034
  
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Microbiota-Induced Type I Interferons Instruct a Poised Basal State of Dendritic Cells

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1. scibot 13 Sep 2020
  
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  DOI: 10.1016/j.cell.2020.04.022
  
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OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis

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1. scibot 03 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.01.028
  
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Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.08.017
  
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Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.09.067
  
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Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.11.042
  
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.02.017
  
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sciencedirect.com/science/article/pii/S2211124719301792
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Untitled document

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.chom.2019.02.004
  
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Nov 2018
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Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6365216/
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The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages

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1. scibot 05 Nov 2018
  
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LAG3+ Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1+ Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven Colitis

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1. scibot 05 Nov 2018
  
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Untitled document

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Co-inhibitory Molecule B7 Superfamily Member 1 Expressed by Tumor-Infiltrating Myeloid Cells Induces Dysfunction of Anti-tumor CD8+ T Cells

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1. scibot 05 Nov 2018
  
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