Hypothesis

20 Matching Annotations

Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

YAP/TAZ transcriptional co-activators create therapeutic vulnerability to verteporfin in EGFR mutant glioblastoma

1
1. scibot 08 Nov 2025
  
  in Public
  
  AB_1080602
  
  DOI: 10.1158/1078-0432.CCR-20-0018
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602
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RRID:AB_1080602

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC8440125/
Sep 2025
www.sciencedirect.com www.sciencedirect.com

Endogenous YAP/TAZ partitioning in TEAD condensates orchestrates the Hippo response

1
1. scibot 06 Sep 2025
  
  in Public
  
  AB_1080602
  
  DOI: 10.1016/j.molcel.2025.08.014
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602
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RRID:AB_1080602

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scibot

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sciencedirect.com/science/article/pii/S1097276525006641
Aug 2025
www.science.org www.science.org

Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

1
1. scibot 14 Aug 2025
  
  in Public
  
  RRID:AB_1080602
  
  DOI: 10.1126/sciadv.abf9141
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602
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RRID:AB_1080602

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scibot

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science.org/doi/10.1126/sciadv.abf9141
Jul 2024
www.cell.com www.cell.com

Human trophectoderm becomes multi-layered by internalization at the polar region

1
1. scibot 18 Jul 2024
  
  in Public
  
  RRID:AB_1080602
  
  DOI: 10.1016/j.devcel.2024.05.028
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602
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scibot

URL

cell.com/developmental-cell/abstract/S1534-5807(24)00362-9
Mar 2024
www.sciencedirect.com www.sciencedirect.com

Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling

1
1. scibot 29 Mar 2024
  
  in Public
  
  RRID:AB_1080602
  
  DOI: 10.1016/j.chembiol.2024.02.013
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602
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sciencedirect.com/science/article/pii/S2451945624000874
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hippo signaling impairs alveolar epithelial regeneration in pulmonary fibrosis

1
1. scibot 27 May 2023
  
  in Public
  
  RRID:AB_1080602
  
  DOI: 10.7554/eLife.85092
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602
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URL

ncbi.nlm.nih.gov/pmc/articles/PMC10208641/
Mar 2023
www.embopress.org www.embopress.org

Two Hippo signaling modules orchestrate liver size and tumorigenesis

2
1. scibot 16 Mar 2023
  
  in Public
  
  RRID:AB_1080602
  
  DOI: 10.15252/embj.2022112126
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602
2. scibot 16 Mar 2023
  
  in Public
  
  RRID:AB_1080602
  
  DOI: 10.15252/embj.2022112126
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602
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RRID:AB_1080602

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embopress.org/doi/10.15252/embj.2022112126
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers

1
1. scibot 31 Aug 2022
  
  in Public
  
  RRID:AB_1080602
  
  DOI: 10.1016/j.celrep.2022.111296
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602
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sciencedirect.com/science/article/pii/S2211124722011160
Jun 2022
www.sciencedirect.com www.sciencedirect.com

YAP1 maintains active chromatin state in head and neck squamous cell carcinomas that promotes tumorigenesis through cooperation with BRD4

1
1. scibot 15 Jun 2022
  
  in Public
  
  RRID:AB_1080602
  
  DOI: 10.1016/j.celrep.2022.110970
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602
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sciencedirect.com/science/article/pii/S2211124722007562
Apr 2022
www.sciencedirect.com www.sciencedirect.com

WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy

1
1. scibot 20 Apr 2022
  
  in Public
  
  RRID:AB_1080602
  
  DOI: 10.1016/j.molcel.2022.03.027
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602
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sciencedirect.com/science/article/pii/S1097276522002659
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines

1
1. scibot 15 Aug 2021
  
  in Public
  
  RRID:AB_1080602
  
  DOI: 10.1016/j.isci.2021.102807
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602
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ncbi.nlm.nih.gov/pmc/articles/PMC8313754/
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis

1
1. scibot 14 Jul 2021
  
  in Public
  
  RRID:AB_1080602
  
  DOI: 10.1016/j.celrep.2021.109347
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602
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RRID:AB_1080602

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sciencedirect.com/science/article/pii/S2211124721007233
Jun 2021
www.science.org www.science.org

Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

1
1. scibot 17 Jun 2021
  
  in Public
  
  RRID:AB_1080602
  
  DOI: 10.1126/sciadv.abf9141
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602
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RRID:AB_1080602

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URL

science.org/doi/10.1126/sciadv.abf9141
Feb 2021
elifesciences.org elifesciences.org

Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade

1
1. scibot 25 Feb 2021
  
  in Public
  
  RRID:AB_1080602
  
  DOI: 10.7554/eLife.43996
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602
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URL

elifesciences.org/articles/43996
Jan 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_1080602
  
  DOI: 10.7554/eLife.40167
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_1080602

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6307859/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:AB_1080602
  
  DOI: 10.7554/eLife.43996
  
  Resource: (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_1080602
  
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  RRID:AB_1080602 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_1080602

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6461440/
Nov 2018
academic.oup.com academic.oup.com

Targeted Disruption of YAP and TAZ Impairs the Maintenance of the Adrenal Cortex

1
1. scibot 05 Nov 2018
  
  in Public
  
  AB_1080602
  
  Curator: @evieth
  
  Resource used:
  
  (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  SciCrunch record: RRID:AB_1080602
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_1080602 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_1080602

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scibot

URL

academic.oup.com/endo/article/158/11/3738/4158185
Nov 2017
www.sciencedirect.com www.sciencedirect.com

An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_1080602
  
  Curator: @ifroman
  
  Resource used:
  
  (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  SciCrunch record: RRID:AB_1080602
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_1080602 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_1080602

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scibot

URL

sciencedirect.com/science/article/pii/S1934590917300942
www.sciencedirect.com www.sciencedirect.com

TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_1080602
  
  Curator: @kaitlinsung
  
  Resource used:
  
  (Sigma-Aldrich Cat# HPA007415, RRID:AB_1080602)
  
  SciCrunch record: RRID:AB_1080602
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:AB_1080602 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:AB_1080602

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scibot

URL

sciencedirect.com/science/article/pii/S1535610817301034