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Discovery and preclinical validation of a translationally optimized mitochondrial complex I modulator for Alzheimer’s disease

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1. scibot 10 Sep 2026
  
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  RRID:AB_10828246
  
  DOI: 10.1038/s44386-026-00072-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13538682/
Jul 2026
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SIRT3 deficiency drives alveolar epithelial mitochondrial dysfunction in bronchopulmonary dysplasia via PDHA1 hyperacetylation

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1. scibot 03 Jul 2026
  
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  DOI: 10.1016/j.isci.2026.116552
  
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sciencedirect.com/science/article/pii/S2589004226019279
May 2026
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Mechanism of action of synaptic mitochondrial damage in delayed cognitive recovery

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1. scibot 29 May 2026
  
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  DOI: 10.4103/NRR.NRR-D-24-01126
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13211829/
Apr 2026
www.biorxiv.org www.biorxiv.org

Discovery and Preclinical Validation of a Clinically Optimized Mitochondrial Complex I Modulator for Alzheimer’s Disease

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1. scibot 24 Apr 2026
  
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  RRID:AB_10828246
  
  DOI: 10.64898/2026.04.10.717554
  
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biorxiv.org/content/10.64898/2026.04.10.717554v1
Oct 2025
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Combined HDAC and eIF4A inhibition: A novel epigenetic therapy for pancreatic ductal adenocarcinoma

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.drup.2025.101312
  
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sciencedirect.com/science/article/pii/S1368764625001153
Sep 2025
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Therapeutic assessment of a novel mitochondrial complex I inhibitor in in vitro and in vivo models of Alzheimer's disease

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1. scibot 16 Sep 2025
  
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  DOI: 10.1016/j.ebiom.2025.105924
  
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sciencedirect.com/science/article/pii/S2352396425003688
Mar 2025
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Therapeutic assessment of a novel mitochondrial complex I inhibitor in in vitro and in vivo models of Alzheimer’s disease

1
1. scibot 13 Mar 2025
  
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  RRID:AB_10828246
  
  DOI: 10.1101/2025.02.12.637918
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11870434/
Jan 2025
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The mitochondrial DNAJC co-chaperone TCAIM reduces α-ketoglutarate dehydrogenase protein levels to regulate metabolism

1
1. scibot 31 Jan 2025
  
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  DOI: 10.1016/j.molcel.2025.01.006
  
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sciencedirect.com/science/article/pii/S109727652500036X
Dec 2024
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Mitochondrial pyruvate transport regulates presynaptic metabolism and neurotransmission

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1. scibot 21 Dec 2024
  
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  RRID:AB_10828246
  
  DOI: 10.1126/sciadv.adp7423
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11567002/
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Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing

1
1. scibot 21 Dec 2024
  
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  RRID:AB_10828246
  
  DOI: 10.1038/s41586-024-08348-2
  
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nature.com/articles/s41586-024-08348-2
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Mitochondrial pyruvate transport regulates presynaptic metabolism and neurotransmission

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1. scibot 20 Dec 2024
  
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  RRID:AB_10828246
  
  DOI: 10.1126/sciadv.adp7423
  
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science.org/doi/10.1126/sciadv.adp7423
Oct 2024
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Mitochondria remodeling during endometrial stromal cell decidualization

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1. scibot 08 Oct 2024
  
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  AB_10828246
  
  DOI: 10.26508/lsa.202402627
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11452479/
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice

1
1. scibot 09 Jun 2024
  
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  RRID:AB_10828246
  
  DOI: 10.1016/j.isci.2024.109991
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11154205/
Mar 2024
link.springer.com link.springer.com

The NADase CD38 is a central regulator in gouty inflammation and a novel druggable therapeutic target

1
1. scibot 26 Mar 2024
  
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  RRID:AB_10828246
  
  DOI: 10.1007/s00011-024-01863-y
  
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link.springer.com/article/10.1007/s00011-024-01863-y
Feb 2024
52.53.155.43 52.53.155.43

bqae017-html.html

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1. scibot 15 Feb 2024
  
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  RRID:AB_10828246
  
  DOI: 10.1210/endocr/bqae017
  
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52.53.155.43/9c72c745490b3db285639bf374976e6a5c602912/bqae017-html.html
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The human OPA1delTTAG mutation induces adult onset and progressive auditory neuropathy in mice

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1. scibot 14 Feb 2024
  
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  RRID:AB_10828246
  
  DOI: 10.1007/s00018-024-05115-4
  
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link.springer.com/article/10.1007/s00018-024-05115-4
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Increased SIRT3 combined with PARP inhibition rescues motor function of SBMA mice

1
1. scibot 10 Aug 2023
  
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  RRID:AB_10828246
  
  DOI: 10.1016/j.isci.2023.107375
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10433013/
May 2023
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Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity

1
1. scibot 26 May 2023
  
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  RRID:AB_10828246
  
  DOI: 10.1016/j.ccell.2023.04.018
  
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sciencedirect.com/science/article/pii/S1535610823001629
Jan 2023
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 14 Jan 2023
  
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  RRID:AB_10828246
  
  DOI: 10.1111/bph.15980
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15980
Jul 2022
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The role and mechanism of CREBH regulating SIRT3 in metabolic associated fatty liver disease

1
1. scibot 27 Jul 2022
  
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  RRID:AB_10828246
  
  DOI: 10.1016/j.lfs.2022.120838
  
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sciencedirect.com/science/article/pii/S0024320522005380
Jun 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

High-intensity interval training remodels the proteome and acetylome of human skeletal muscle

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1. scibot 04 Jun 2022
  
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  RRID:AB_10828246
  
  DOI: 10.7554/eLife.69802
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9154743/
Apr 2022
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SENP1-Sirt3 signaling promotes α-ketoglutarate production during M2 macrophage polarization

1
1. scibot 14 Apr 2022
  
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  RRID:AB_10828246
  
  DOI: 10.1016/j.celrep.2022.110660
  
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sciencedirect.com/science/article/pii/S2211124722004120
Mar 2022
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A reversible metabolic stress-sensitive regulation of CRMP2A orchestrates EMT/stemness and increases metastatic potential in cancer

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1. scibot 16 Mar 2022
  
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  RRID:AB_10828246
  
  DOI: 10.1016/j.celrep.2022.110511
  
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sciencedirect.com/science/article/pii/S2211124722002479
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Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake

1
1. scibot 16 Mar 2022
  
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  RRID:AB_10828246
  
  DOI: 10.1016/j.celrep.2022.110509
  
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sciencedirect.com/science/article/pii/S2211124722002455
Nov 2021
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Interplay between protein acetylation and ubiquitination controls MCL1 protein stability

1
1. scibot 10 Nov 2021
  
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  RRID:AB_10828246
  
  DOI: 10.1016/j.celrep.2021.109988
  
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sciencedirect.com/science/article/pii/S2211124721014674
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communication

1
1. scibot 15 Aug 2021
  
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  RRID:AB_10828246
  
  DOI: 10.7554/eLife.59828
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8331182/
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Annexin A1 Tripeptide Mimetic Increases Sirtuin-3 and Augments Mitochondrial Function to Limit Ischemic Kidney Injury

1
1. scibot 17 Jul 2021
  
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  RRID:AB_10828246
  
  DOI: 10.3389/fphys.2021.683098
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8281307/
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SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis

1
1. scibot 14 Jul 2021
  
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  RRID:AB_10828246
  
  DOI: 10.1016/j.celrep.2021.109345
  
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sciencedirect.com/science/article/pii/S221112472100721X
May 2021
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Mitochondrial SIRT3 confers neuroprotection in Huntington’s disease by regulation of oxidative challenges and mitochondrial dynamics

1
1. scibot 13 May 2021
  
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  SIRT3 (D22A3) (anti-rabbit)
  
  DOI: 10.1016/j.freeradbiomed.2020.11.031
  
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sciencedirect.com/science/article/pii/S0891584920316440
Jan 2021
elifesciences.org elifesciences.org

Remodeling of whole-body lipid metabolism and a diabetic-like phenotype caused by loss of CDK1 and hepatocyte division

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1. scibot 05 Jan 2021
  
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  RRID:AB_10828246
  
  DOI: 10.7554/eLife.63835
  
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  RRID:AB_10828246 RRIDCUR:Validated
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elifesciences.org/articles/63835
Dec 2020
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HIV TAT-mediated microglial senescence: Role of SIRT3-dependent mitochondrial oxidative stress

1
1. scibot 30 Dec 2020
  
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  Rabbit monoclonal anti-SIRT3
  
  DOI: 10.1016/j.redox.2020.101843
  
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sciencedirect.com/science/article/pii/S221323172031048X
Oct 2020
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Impaired flickering of the permeability transition pore causes SPG7 spastic paraplegia

1
1. scibot 13 Oct 2020
  
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  RRID:AB_10828246
  
  DOI: 10.1016/j.ebiom.2020.103050
  
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sciencedirect.com/science/article/pii/S2352396420304266
Sep 2020
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 16 Sep 2020
  
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  RRID:AB_10828246
  
  DOI: 10.1111/bph.15159
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15159
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1

1
1. scibot 13 Jan 2020
  
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  RRID:AB_10828246
  
  DOI: 10.1016/j.molcel.2019.07.023
  
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  Curator: @ethanbadger
  
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  RRID:AB_10828246 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276519305532
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Low-Level Saturated Fatty Acid Palmitate Benefits Liver Cells by Boosting Mitochondrial Metabolism via CDK1-SIRT3-CPT2 Cascade

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1. scibot 13 Jan 2020
  
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  RRID:AB_10828246
  
  DOI: 10.1016/j.devcel.2019.11.012
  
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  Curator: @ethanbadger
  
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  RRID:AB_10828246 RRIDCUR:Validated
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SENP1-Sirt3 Signaling Controls Mitochondrial Protein Acetylation and Metabolism

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  DOI: 10.1016/j.molcel.2019.06.008
  
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Non-oncogene Addiction to SIRT3 Plays a Critical Role in Lymphomagenesis

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  DOI: 10.1016/j.ccell.2019.05.002
  
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Untitled document

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Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3‐dependent mechanism in male mice

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  DOI: 10.1002/jnr.24397
  
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Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations

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