40 Matching Annotations
  1. Dec 2023
  2. www.sciencedirect.com www.sciencedirect.com
    MORG1 limits mTORC1 signaling by inhibiting Rag GTPases
    1
    1. scibot 16 Dec 2023
      RRID:AB_10829226

      DOI: 10.1016/j.molcel.2023.11.023

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    sciencedirect.com/science/article/pii/S1097276523009681
  3. www.sciencedirect.com www.sciencedirect.com
    Nutrient-regulated control of lysosome function by signaling lipid conversion
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    1. scibot 02 Dec 2023
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      DOI: 10.1016/j.cell.2023.09.027

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    sciencedirect.com/science/article/pii/S0092867423010814
  4. Aug 2023
  5. 52.53.155.43 52.53.155.43
    PIIS2589004223017029-html.html
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    1. scibot 18 Aug 2023
      RRID:AB_10829226

      DOI: 10.1016/j.isci.2023.107625

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    52.53.155.43/258d74bd1c79cf4d725c254c0f9188b69c056c90/PIIS2589004223017029-html.html
  6. Jun 2023
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Restored autophagy is protective against PAK3-induced cardiac dysfunction
    1
    1. scibot 17 Jun 2023
      RRID:AB_10829226

      DOI: 10.1016/j.isci.2023.106970

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    ncbi.nlm.nih.gov/pmc/articles/PMC10265534/
  8. aacrjournals.org aacrjournals.org
    Dysregulation of mitochondrial translation caused by CBFB deficiency cooperates with mutant PIK3CA and is a vulnerability in breast cancer
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1158/0008-5472.CAN-22-2525

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    aacrjournals.org/cancerres/article/83/8/1280/725099/Dysregulation-of-Mitochondrial-Translation-Caused
  9. May 2023
  10. www.sciencedirect.com www.sciencedirect.com
    Metamorphic proteins at the basis of human autophagy initiation and lipid transfer
    1
    1. scibot 20 May 2023
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      DOI: 10.1016/j.molcel.2023.04.026

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    sciencedirect.com/science/article/pii/S1097276523003210
  11. academic.oup.com academic.oup.com
    Whole-body and forearm muscle protein metabolism in patients with acromegaly before and after treatment
    1
    1. scibot 06 May 2023
      RRID:AB_10829226

      DOI: 10.1210/clinem/dgad190

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgad190/7111800
  12. Apr 2023
  13. www.sciencedirect.com www.sciencedirect.com
    CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth
    1
    1. scibot 06 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112316

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    sciencedirect.com/science/article/pii/S2211124723003273
  14. Feb 2023
  15. www.sciencedirect.com www.sciencedirect.com
    An affinity-directed phosphatase, AdPhosphatase, system for targeted protein dephosphorylation
    1
    1. scibot 02 Feb 2023
      RRID:AB_10829226

      DOI: 10.1016/j.chembiol.2023.01.003

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    sciencedirect.com/science/article/pii/S2451945623000260
  16. Dec 2022
  17. www.sciencedirect.com www.sciencedirect.com
    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
    1
    1. scibot 08 Dec 2022
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      DOI: 10.1016/j.celrep.2022.111653

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    sciencedirect.com/science/article/pii/S2211124722015248
  18. Oct 2022
  19. www.sciencedirect.com www.sciencedirect.com
    Destabilization of TP53 by USP10 is essential for neonatal autophagy and survival
    1
    1. scibot 05 Oct 2022
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      DOI: 10.1016/j.celrep.2022.111435

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    sciencedirect.com/science/article/pii/S2211124722012761
  20. Aug 2022
  21. 52.53.155.43 52.53.155.43
    can-22-0121-html.html
    1
    1. scibot 27 Aug 2022
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      DOI: 10.1158/0008-5472.can-22-0121

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  22. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial hyperfusion via metabolic sensing of regulatory amino acids
    1
    1. scibot 17 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111198

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    sciencedirect.com/science/article/pii/S2211124722010154
  23. Mar 2022
  24. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    DRAM-4 and DRAM-5 are compensatory regulators of autophagy and cell survival in nutrient-deprived conditions
    1
    1. scibot 03 Mar 2022
      RRID:AB_10829226

      DOI: 10.1111/febs.16365

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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.16365
  25. Feb 2022
  26. www.sciencedirect.com www.sciencedirect.com
    An AMPKα2-specific phospho-switch controls lysosomal targeting for activation
    1
    1. scibot 16 Feb 2022
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      DOI: 10.1016/j.celrep.2022.110365

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    sciencedirect.com/science/article/pii/S2211124722000869
  27. journals.plos.org journals.plos.org
    A feature of maternal sleep apnea during gestation causes autism-relevant neuronal and behavioral phenotypes in offspring
    1
    1. scibot 05 Feb 2022
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      DOI: 10.1371/journal.pbio.3001502

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    journals.plos.org/plosbiology/article
  28. Aug 2021
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 01 Aug 2021
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      DOI: 10.1016/j.celrep.2018.07.101

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    ncbi.nlm.nih.gov/pmc/articles/PMC6298213/
  30. Jul 2021
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 30 Jul 2021
      RRID:AB_10829226

      DOI: 10.1016/j.cmet.2018.08.013

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    ncbi.nlm.nih.gov/pmc/articles/PMC6331339/
  32. Jun 2021
  33. www.nature.com www.nature.com
    High-throughput screening for natural compound-based autophagy modulators reveals novel chemotherapeutic mode of action for arzanol
    1
    1. scibot 05 Jun 2021
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      DOI: 10.1038/s41419-021-03830-5

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    nature.com/articles/s41419-021-03830-5
  34. May 2021
  35. www.sciencedirect.com www.sciencedirect.com
    Cell size homeostasis is maintained by CDK4-dependent activation of p38 MAPK
    1
    1. scibot 22 May 2021
      RRID:AB_10829226

      DOI: 10.1016/j.devcel.2021.04.030

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    sciencedirect.com/science/article/pii/S1534580721003993
  36. www.sciencedirect.com www.sciencedirect.com
    Akt-mTOR hypoactivity in bipolar disorder gives rise to cognitive impairments associated with altered neuronal structure and function
    1
    1. scibot 08 May 2021
      RRID:AB_10829226

      DOI: 10.1016/j.neuron.2021.03.008

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    sciencedirect.com/science/article/pii/S0896627321001562
  37. Apr 2021
  38. www.sciencedirect.com www.sciencedirect.com
    Pharmacological Targeting of Vacuolar H+-ATPase via Subunit V1G Combats Multidrug-Resistant Cancer
    1
    1. scibot 27 Apr 2021
      RRID:AB_10829226

      DOI: 10.1016/j.chembiol.2020.06.011

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    sciencedirect.com/science/article/pii/S2451945620302348
  39. www.sciencedirect.com www.sciencedirect.com
    Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer
    1
    1. scibot 24 Apr 2021
      RRID:AB_10829226

      DOI: 10.1016/j.cell.2020.10.016

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    sciencedirect.com/science/article/pii/S0092867420313222
  40. Mar 2021
  41. www.sciencedirect.com www.sciencedirect.com
    Amino acids-Rab1A-mTORC1 signaling controls whole-body glucose homeostasis
    1
    1. scibot 17 Mar 2021
      RRID:AB_10829226

      DOI: 10.1016/j.celrep.2021.108830

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    sciencedirect.com/science/article/pii/S2211124721001443
  42. www.sciencedirect.com www.sciencedirect.com
    Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy
    1
    1. scibot 01 Mar 2021
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      DOI: 10.1016/j.cell.2020.11.018

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    sciencedirect.com/science/article/pii/S009286742031535X
  43. Sep 2020
  44. elifesciences.org elifesciences.org
    Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination
    1
    1. scibot 26 Sep 2020
      RRID:AB_10829226

      DOI: 10.7554/eLife.56811

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    elifesciences.org/articles/56811
  45. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Inducible Degradation of Target Proteins through a Tractable Affinity-Directed Protein Missile System
    1
    1. scibot 23 Sep 2020
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      DOI: 10.1016/j.chembiol.2020.06.013

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    pubmed.ncbi.nlm.nih.gov/32668203/
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
    H63D variant of the homeostatic iron regulator (HFE) gene alters α‐synuclein expression, aggregation, and toxicity
    1
    1. scibot 23 Sep 2020
      RRID:AB_10829226

      DOI: 10.1111/jnc.15107

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15107
  47. www.sciencedirect.com www.sciencedirect.com
    Glycolysis-Independent Glucose Metabolism Distinguishes TE from ICM Fate during Mammalian Embryogenesis
    1
    1. scibot 12 Sep 2020
      RRID:AB_10829226

      DOI: 10.1016/j.devcel.2020.02.015

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    sciencedirect.com/science/article/pii/S1534580720301428
  48. Jan 2020
  49. elifesciences.org elifesciences.org
    Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons
    1
    1. scibot 13 Jan 2020
      RRID:AB_10829226

      DOI: 10.7554/eLife.44219

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    elifesciences.org/articles/44219
  50. www.sciencedirect.com www.sciencedirect.com
    IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration
    1
    1. scibot 13 Jan 2020
      RRID:AB_10829226

      DOI: 10.1016/j.celrep.2019.02.013

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    sciencedirect.com/science/article/pii/S2211124719301755
  51. www.sciencedirect.com www.sciencedirect.com
    Transmembrane 4 L Six Family Member 5 Senses Arginine for mTORC1 Signaling
    1
    1. scibot 12 Jan 2020
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      DOI: 10.1016/j.cmet.2019.03.005

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    sciencedirect.com/science/article/pii/S1550413119301330
  52. Nov 2018
  53. www.sciencedirect.com www.sciencedirect.com
    Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A
    1
    1. scibot 05 Nov 2018
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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S155041311830514X
  54. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S2211124718312348
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC5926201/
  56. www.jneurosci.org www.jneurosci.org
    Untitled document
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    jneurosci.org/content/38/4/1015
  57. Nov 2017
  58. www.sciencedirect.com www.sciencedirect.com
    TREM2 Maintains Microglial Metabolic Fitness in Alzheimer’s Disease
    1
    1. scibot 08 Nov 2017
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0092867417308309
  59. elifesciences.org elifesciences.org
    LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs
    1
    1. scibot 08 Nov 2017
      AB_10829226

      Curator: @chewbeccax

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    elifesciences.org/articles/25237
  60. elifesciences.org elifesciences.org
    Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator
    1
    1. scibot 08 Nov 2017
      AB_10829226

      Curator: @kaitlinsung

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    elifesciences.org/articles/23063
  61. elifesciences.org elifesciences.org
    Dynamics of mTORC1 activation in response to amino acids
    1
    1. scibot 08 Nov 2017
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      Curator: @bandrow

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    elifesciences.org/articles/19960