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Targeting RPL4 improves the therapeutic efficacy of PD-L1 blockade in liver fibrosis

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1. scibot 24 Sep 2026
  
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  DOI: 10.1016/j.xcrm.2026.103056
  
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Sep 2026
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Nuclear body assembly by a viral repeat RNA promotes Kaposi’s sarcoma-associated herpesvirus gene expression

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  DOI: 10.1016/j.molcel.2026.08.022
  
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5-Azacytosine induces cytotoxicity via 5-methylcytosine depletion on chromatin-associated RNA in leukemia

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  DOI: 10.1016/j.molcel.2026.08.018
  
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Aug 2026
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CDK1 regulates NRF2 stability through phosphorylation of USP29 and inhibits neuronal ferroptosis after traumatic brain injury

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Jul 2026
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2026.07.11.737985.full-html.html

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54.241.53.176/abdd4fd49c7ff7fe062e3f7e97d1cb52de6bbb37/2026.07.11.737985.full-html.html
Jun 2026
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Poising and connectivity of emergent human developmental enhancers in the transition from naive to primed pluripotency

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  DOI: 10.1016/j.celrep.2026.117402
  
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A multi-subunit autophagic capture complex facilitates degradation of ER-stalled MHC class I in pancreatic cancer

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May 2026
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TLR4-paxillin-Rac1 signaling mediates LPS-induced dysregulation of keratinocyte function

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1. scibot 22 May 2026
  
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Estrogen Receptor Alpha and Beta Chromatin Interactions Govern Ovarian Folliculogenesis but Dissipate During Ovulation

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1. scibot 21 May 2026
  
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  DOI: 10.1210/endocr/bqag052
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13184623/
Mar 2026
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Host-transposon mutualism supports regeneration in planarians

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  DOI: 10.1016/j.devcel.2026.03.001
  
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STUB1-VCP/p97 complex regulates mitophagy via fine-tuning of PINK1 levels

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1. scibot 31 Mar 2026
  
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  DOI: 10.1016/j.celrep.2026.117183
  
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ROME, an Ancient Gene with a Novel Function in Vertebrates, Is a Key Modulator of Embryonal Development and Cancer Metastasis

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1. scibot 26 Mar 2026
  
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  DOI: 10.1158/2767-9764.CRC-26-0068
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13012068/
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FBXO3-mediated DUSP9 ubiquitination promotes leukemia stem cell maintenance and tyrosine kinase inhibitor resistance in chronic myeloid leukemia

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1. scibot 20 Mar 2026
  
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  DOI: 10.1016/j.xcrm.2026.102686
  
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CircRNA-encoded RIPK1-98 protein drives lung adenocarcinoma progression

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1. scibot 13 Mar 2026
  
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  DOI: 10.1016/j.devcel.2026.02.014
  
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Jan 2026
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Protocol for identification of protein citrullination by immunoprecipitation followed by mass spectrometry

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1. scibot 16 Jan 2026
  
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  DOI: 10.1016/j.xpro.2025.104326
  
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Ubiquitination and degradation of CD47 enhances macrophage phagocytosis of hemolytic erythrocytes

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.isci.2025.114499
  
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Nov 2025
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Chromatin remodeler Chd7 regulates reactive astrogliosis after ischemic stroke

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1. scibot 22 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116590
  
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Oct 2025
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Targeted citrullination enables p53 binding to non-canonical sites

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.molcel.2025.09.004
  
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YEATS4 reads histone crotonylation to promote fatty acid metabolism and cancer cell stemness

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1. scibot 08 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116400
  
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Sep 2025
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2025.09.04.674332v2.full-html.html

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1. scibot 18 Sep 2025
  
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  DOI: 10.1101/2025.09.04.674332
  
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52.53.155.43/304402c0b5b5e8844bb324b2732dfcb1e481f20c/2025.09.04.674332v2.full-html.html
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A pathological role of O-GlcNAcylation-driven TR11B production and function in lung adenocarcinoma

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Jul 2025
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1-s2.0-S2589004225013203-main-html.html

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1. scibot 08 Jul 2025
  
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52.53.155.43/cf5e79d9430fe2c0516d8255d5ed63fff73c6faf/1-s2.0-S2589004225013203-main-html.html
Jun 2025
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Altered cofactor recruitment and nucleosome dynamics underlie bisphenol A’s impact on ERα-mediated transcriptional bursting

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112864
  
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Vault RNAs aid RNA virus infection by facilitating cytoplasmic localization of hnRNP C and ELAVL1

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PDF-html.html

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  DOI: 10.1158/1535-7163.mct-24-0944
  
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52.53.155.43/ede022ae23233744b77af4278ec3faa8fd0a91c6/PDF-html.html
May 2025
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Circular RNA circATM binds PARP1 to suppress Wnt/β-catenin signaling and induce cell cycle arrest in gastric cancer cells

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  DOI: 10.1016/j.jare.2025.04.033
  
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Mitochondrial CCN1 drives ferroptosis via fatty acid β-oxidation

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  DOI: 10.1016/j.devcel.2025.04.004
  
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Apr 2025
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Cytosolic cytochrome c represses ferroptosis

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  DOI: 10.1016/j.cmet.2025.03.014
  
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Mar 2025
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Ginsenoside Rg1 alleviates chronic stress-induced depression in rats by targeting Cx43-YAP axis

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  DOI: 10.1038/s41401-025-01515-9
  
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link.springer.com/article/10.1038/s41401-025-01515-9
Feb 2025
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USP5 stabilizes YTHDF1 to control cancer immune surveillance through mTORC1-mediated phosphorylation

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  DOI: 10.1038/s41467-025-56564-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11791202/
Dec 2024
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DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states

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1. scibot 05 Dec 2024
  
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  DOI: 10.1016/j.molcel.2024.11.009
  
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Nov 2024
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miRNA-mediated control of gephyrin synthesis drives sustained inhibitory synaptic plasticity

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1. scibot 14 Nov 2024
  
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  DOI: 10.1038/s44319-024-00253-z
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11549329/
Jul 2024
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A Kinome-Wide Synthetic Lethal CRISPR/Cas9 Screen Reveals That mTOR Inhibition Prevents Adaptive Resistance to CDK4/CDK6 Blockade in HNSCC

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1. scibot 31 Jul 2024
  
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  DOI: 10.1158/2767-9764.CRC-24-0247
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11284272/
Apr 2024
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AIbZIP/CREB3L4 Promotes Cell Proliferation via the SKP2-p27 Axis in Luminal Androgen Receptor Subtype Triple Negative Breast Cancer

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1. scibot 05 Apr 2024
  
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  DOI: 10.1158/1541-7786.MCR-23-0629
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10985479/
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TMC7 functions as a suppressor of Piezo2 in primary sensory neurons blunting peripheral mechanotransduction

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1. scibot 04 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114014
  
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The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury

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Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation

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Single-cell functional genomics reveals determinants of sensitivity and resistance to natural killer cells in blood cancers

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MORG1 limits mTORC1 signaling by inhibiting Rag GTPases

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TET3 plays a critical role in white adipose development and diet-induced remodeling

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Molecular basis for nuclear accumulation and targeting of the inhibitor of apoptosis BIRC2

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Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice

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Selective activation of PPARα maintains thermogenic capacity of beige adipocytes

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The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity

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Nuclear translocation of an aminoacyl-tRNA synthetase may mediate a chronic “integrated stress response”

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Hypoxia-induced loss of SRSF2-dependent DNA methylation promotes CTCF-mediated alternative splicing of VEGFA in breast cancer

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Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia

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UTP18-mediated p21 mRNA instability drives adenoma-carcinoma progression in colorectal cancer

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STING activation in platelets aggravates septic thrombosis by enhancing platelet activation and granule secretion

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Phosphoenolpyruvate regulates the Th17 transcriptional program and inhibits autoimmunity

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The insulin and IGF signaling pathway sustains breast cancer stem cells by IRS2/PI3K-mediated regulation of MYC

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RSPO2 promotes progression of ovarian cancer through dual receptor-mediated FAK/Src signaling activation

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Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation

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Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6‐dependent pathway

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Tissue remodeling by an opportunistic pathogen triggers allergic inflammation

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Wnt signaling is boosted during intestinal regeneration by a CD44-positive feedback loop

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CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities

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Overriding impaired FPR chemotaxis signaling in diabetic neutrophil stimulates infection control in murine diabetic wound

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Matrix remodeling controls a nuclear lamin A/C-emerin network that directs Wnt-regulated stem cell fate

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Distal and proximal cis-regulatory elements sense X chromosome dosage and developmental state at the Xist locus

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Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation

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ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis

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NRF2 promotes urothelial cell response to bacterial infection by regulating reactive oxygen species and RAB27B expression

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Enhanced eosinophil-mediated inflammation associated with antibody and complement-dependent pneumonic insults in critical COVID-19

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Transcriptional control of brain tumor stem cells by a carbohydrate binding protein

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Untitled document

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An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion

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A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing

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ncbi.nlm.nih.gov/pmc/articles/PMC8186904/
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ELAVL1 primarily couples mRNA stability with the 3′ UTRs of interferon-stimulated genes

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  DOI: 10.1016/j.celrep.2021.109178
  
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  DOI: 10.1111/bph.15340
  
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Targeting KDM4A epigenetically activates tumor-cell-intrinsic immunity by inducing DNA replication stress

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  DOI: 10.1111/bph.15378
  
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Local miRNA-Dependent Translational Control of GABAAR Synthesis during Inhibitory Long-Term Potentiation

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cell.com/cell-reports/fulltext/S2211-1247(20)30765-8
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Discovery of Widespread Host Protein Interactions with the Pre-replicated Genome of CHIKV Using VIR-CLASP

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Inactivation of the tyrosine phosphatase SHP-2 drives vascular dysfunction in Sepsis

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Parvovirus Minute Virus of Mice Interacts with Sites of Cellular DNA Damage to Establish and Amplify its Lytic Infection

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Pbrm1 Steers Mesenchymal Stromal Cell Osteolineage Differentiation by Integrating PBAF-Dependent Chromatin Remodeling and BMP/TGF-β Signaling

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RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer

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Fructose-1,6-Bisphosphatase 2 Inhibits Sarcoma Progression by Restraining Mitochondrial Biogenesis

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  DOI: 10.1016/j.cmet.2019.10.012
  
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  DOI: 10.1111/bph.14770
  
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bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.14770
Nov 2018
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A Chemical-Genetic Approach Reveals the Distinct Roles of GSK3α and GSK3β in Regulating Embryonic Stem Cell Fate.

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Neuronal activity‐dependent local activation of dendritic unfolded protein response promotes expression of brain‐derived neurotrophic factor in cell soma

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onlinelibrary.wiley.com/doi/10.1111/jnc.14221/full
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Untitled document

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Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer

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sciencedirect.com/science/article/pii/S0092867417312448
Nov 2017
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Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function

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sciencedirect.com/science/article/pii/S109727651730312X

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