18 Matching Annotations
  1. Feb 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting
    1
    1. scibot 21 Feb 2024
      RRID:AB_10835146

      DOI: 10.1016/j.molcel.2024.01.022

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    sciencedirect.com/science/article/pii/S1097276524000893
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting BET proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML
    1
    1. scibot 02 Feb 2024
      RRID:AB_10835146

      DOI: 10.1158/1078-0432.CCR-22-3929

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524644/
  4. Jan 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bromodomain inhibitor i-BET858 triggers a unique transcriptional response coupled to enhanced DNA damage, cell cycle arrest and apoptosis in high-grade ovarian carcinoma cells
    1
    1. scibot 26 Jan 2024
      AB_10835146

      DOI: 10.1186/s13148-023-01477-x

      Resource: (Cell Signaling Technology Cat# 5848, RRID:AB_10835146)

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    ncbi.nlm.nih.gov/pmc/articles/PMC10105475/
  6. Aug 2023
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BET Inhibitors Target the SCLC-N subtype of Small Cell Lung Cancer by Blocking NEUROD1 Transactivation
    1
    1. scibot 02 Aug 2023
      RRID:AB_10835146

      DOI: 10.1158/1541-7786.MCR-22-0594

      Resource: (Cell Signaling Technology Cat# 5848, RRID:AB_10835146)

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    ncbi.nlm.nih.gov/pmc/articles/PMC9898120/
  8. Apr 2023
  9. www.science.org www.science.org
    Targeting BRD3 eradicates nuclear TYRO3-induced colorectal cancer metastasis
    2
    1. scibot 20 Apr 2023
      RRID:AB_10835146

      DOI: 10.1126/sciadv.ade3422

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    2. scibot 14 Apr 2023
      RRID:AB_10835146

      DOI: 10.1126/sciadv.ade3422

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    science.org/doi/10.1126/sciadv.ade3422
  10. Feb 2023
  11. 52.53.155.43 52.53.155.43
    91-html.html
    1
    1. scibot 11 Feb 2023
      RRID:AB_10835146

      DOI: 10.1158/1541-7786.MCR-22-0594

      Resource: (Cell Signaling Technology Cat# 5848, RRID:AB_10835146)

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    52.53.155.43/67ba005538cc0cc62d34c50598f914c3efc88864/91-html.html
  12. Jan 2023
  13. aacrjournals.org aacrjournals.org
    Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non–Small Cell Lung Cancer Cells
    1
    1. scibot 14 Jan 2023
      RRID:AB_10835146

      DOI: 10.1158/1541-7786.MCR-21-1000

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    aacrjournals.org/mcr/article/20/12/1785/710999/Loss-of-VOPP1-Contributes-to-BET-Inhibitor
  14. Sep 2022
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CTCF DNA-binding domain undergoes dynamic and selective protein–protein interactions
    1
    1. scibot 22 Sep 2022
      RRID:AB_10835146

      DOI: 10.1016/j.isci.2022.105011

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    ncbi.nlm.nih.gov/pmc/articles/PMC9474293/
  16. Jul 2021
  17. mcr.aacrjournals.org mcr.aacrjournals.org
    Intron 1-Mediated Regulation of EGFR Expression In EGFR-Dependent Malignancies is Mediated by AP-1 and BET Proteins
    1
    1. scibot 31 Jul 2021
      anti-BRD2

      DOI: 10.1158/1541-7786.MCR-19-0747

      Resource: (Cell Signaling Technology Cat# 5848, RRID:AB_10835146)

      Curator: @Naa003

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      RRID:AB_10835146 RRIDCUR:Missing
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    mcr.aacrjournals.org/content/17/11/2208
  18. May 2021
  19. www.sciencedirect.com www.sciencedirect.com
    Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
    1
    1. scibot 21 May 2021
      RRID:AB_10835146

      DOI: 10.1016/j.molcel.2021.04.015

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    sciencedirect.com/science/article/pii/S1097276521003208
  20. www.sciencedirect.com www.sciencedirect.com
    Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer
    1
    1. scibot 07 May 2021
      RRID:AB_10835146

      DOI: 10.1016/j.molcel.2020.04.027

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    sciencedirect.com/science/article/pii/S1097276520302690
  21. Mar 2021
  22. www.sciencedirect.com www.sciencedirect.com
    TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains
    1
    1. scibot 29 Mar 2021
      RRID:AB_10835146

      DOI: 10.1016/j.molcel.2021.01.023

      Resource: (Cell Signaling Technology Cat# 5848, RRID:AB_10835146)

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    sciencedirect.com/science/article/pii/S1097276521000435
  23. Feb 2021
  24. academic.oup.com academic.oup.com
    BET inhibition by JQ1 produces divergent transcriptional regulation of SOCS genes in adipocytes
    1
    1. scibot 24 Feb 2021
      RRID:AB_10835146

      DOI: 10.1210/endocr/bqz034

      Resource: (Cell Signaling Technology Cat# 5848, RRID:AB_10835146)

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    academic.oup.com/endo/article/161/2/bqz034/5686880
  25. Sep 2020
  26. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    BRD4 Prevents R-Loop Formation and Transcription-Replication Conflicts by Ensuring Efficient Transcription Elongation
    1
    1. scibot 25 Sep 2020
      RRID:AB_10835146

      DOI: 10.1016/j.celrep.2020.108166

      Resource: (Cell Signaling Technology Cat# 5848, RRID:AB_10835146)

      Curator: @Naa003

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      RRIDCUR:Validated RRID:AB_10835146
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    pubmed.ncbi.nlm.nih.gov/32966794/
  27. Jan 2020
  28. www.sciencedirect.com www.sciencedirect.com
    A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor
    1
    1. scibot 13 Jan 2020
      RRID:AB_10835146

      DOI: 10.1016/j.ccell.2019.06.002

      Resource: (Cell Signaling Technology Cat# 5848, RRID:AB_10835146)

      Curator: @ethanbadger

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      RRID:AB_10835146 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610819302934
  29. Nov 2018
  30. www.sciencedirect.com www.sciencedirect.com
    Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy
    1
    1. scibot 05 Nov 2018
      RRID:AB_10835146

      Curator: @Jmenke

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      (Cell Signaling Technology Cat# 5848S, RRID:AB_10835146)

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      RRID:AB_10835146 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S009286741831239X
  31. www.sciencedirect.com www.sciencedirect.com
    BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency
    1
    1. scibot 05 Nov 2018
      RRID:AB_10835146

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      (Cell Signaling Technology Cat# 5848S, RRID:AB_10835146)

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      RRID:AB_10835146
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    sciencedirect.com/science/article/pii/S1535610818300199