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  1. Last 7 days
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    The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening
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    1. scibot 19 Jul 2024
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    sciencedirect.com/science/article/pii/S1550413124002316
  3. Jun 2024
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    Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells
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  5. Apr 2024
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    Oct4 controls basement membrane development during human embryogenesis
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    Harnessing developmental dynamics of spinal cord extracellular matrix improves regenerative potential of spinal cord organoids
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  8. Jan 2024
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    Selective induction of human renal interstitial progenitor-like cell lineages from iPSCs reveals development of mesangial and EPO-producing cells
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    sciencedirect.com/science/article/pii/S2211124723016145
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    Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer
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    Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells
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  12. Dec 2023
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    Human iPSC-derived renal collecting duct organoid model cystogenesis in ADPKD
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  14. Nov 2023
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    Highly-parallel production of designer organoids by mosaic patterning of progenitors
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    biorxiv.org/content/10.1101/2023.10.25.564017v1
  16. Sep 2023
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    3D-cultured blastoids model human embryogenesis from pre-implantation to early gastrulation stages
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    sciencedirect.com/science/article/pii/S1934590923002886
  18. Jun 2023
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    Spatially resolved multi-omics single-cell analyses inform mechanisms of immune-dysfunction in pancreatic cancer
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    Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation
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    sciencedirect.com/science/article/pii/S1074761323002273
  21. May 2023
  22. 52.53.155.43 52.53.155.43
    Efficient self-organization of blastoids solely from mouse ESCs is facilitated by transient reactivation of 2C gene network
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    Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture
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    Establishment of bovine trophoblast stem cells
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    sciencedirect.com/science/article/pii/S2211124723004503
  25. Apr 2023
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    Integrative dissection of gene regulatory elements at base resolution
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    sciencedirect.com/science/article/pii/S2666979X23000861
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    A genome-wide CRISPR screen maps endogenous regulators of PPARG gene expression in bladder cancer
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    sciencedirect.com/science/article/pii/S2589004223006028
  28. Mar 2023
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    Polarity inversion reorganizes the stem cell compartment of the trophoblast lineage
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    sciencedirect.com/science/article/pii/S2211124723003248
  30. Nov 2022
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    Protocol to isolate mature thymic T cell subsets using fluorescence-activated cell sorting for assessing gene expression by RNA-seq and transcription factor binding across the genome by CUT&RUN
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    sciencedirect.com/science/article/pii/S2666166722007195
  32. Sep 2022
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    Single-cell analysis of embryoids reveals lineage diversification roadmaps of early human development
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  34. Aug 2022
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    Single-cell and spatial mapping Identify cell types and signaling Networks in the human ureter
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  36. Jun 2022
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    Protocol for the generation and expansion of human iPS cell-derived ureteric bud organoids
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    sciencedirect.com/science/article/pii/S2666166722003641
  38. Apr 2022
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    Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma
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    sciencedirect.com/science/article/pii/S2211124722004533
  40. Mar 2022
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    dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
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    sciencedirect.com/science/article/pii/S221112472200184X
  42. Sep 2021
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells
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      DOI: 10.7554/eLife.67259

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    ncbi.nlm.nih.gov/pmc/articles/PMC8410071/
  44. Mar 2021
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    Systematic characterization of mutations altering protein degradation in human cancers
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    sciencedirect.com/science/article/pii/S109727652100040X
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    GATA transcription factors, SOX17 and TFAP2C, drive the human germ-cell specification program
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      DOI: 10.26508/lsa.202000974

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    ncbi.nlm.nih.gov/pmc/articles/PMC7918644/
  47. Feb 2021
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Two distinct trophectoderm lineage stem cells from human pluripotent stem cells
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      DOI: 10.1016/j.jbc.2021.100386

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    ncbi.nlm.nih.gov/pmc/articles/PMC7948510/
  49. Dec 2020
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    High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures
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      DOI: 10.7554/eLife.59445

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    ncbi.nlm.nih.gov/pmc/articles/PMC7728446/
  51. Sep 2020
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    A Modular Differentiation System Maps Multiple Human Kidney Lineages from Pluripotent Stem Cells
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    sciencedirect.com/science/article/pii/S2211124720303545
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    Gata3-controlled nucleosome eviction drives Myc enhancer activity in T-cell development and leukemia
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      DOI: 10.1158/2159-8290.CD-19-0471

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    cancerdiscovery.aacrjournals.org/content/9/12/1774
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    GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells
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    Expansion of Human iPSC-Derived Ureteric Bud Organoids with Repeated Branching Potential
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      DOI: 10.1016/j.celrep.2020.107963

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    sciencedirect.com/science/article/pii/S221112472030944X
  56. Aug 2020
  57. www.sciencedirect.com www.sciencedirect.com
    Evolution of the immune landscape during progression of pancreatic intraductal papillary mucinous neoplasms to invasive cancer
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      DOI: 10.1016/j.ebiom.2020.102714

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    sciencedirect.com/science/article/pii/S235239642030089X
  58. Jan 2020
  59. www.sciencedirect.com www.sciencedirect.com
    Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer
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      DOI: 10.1016/j.celrep.2019.08.076

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    sciencedirect.com/science/article/pii/S2211124719311313
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    A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis
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    1. scibot 12 Jan 2020
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      DOI: 10.1016/j.ccell.2018.10.004

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    sciencedirect.com/science/article/pii/S1535610818304707
  61. Nov 2018
  62. www.sciencedirect.com www.sciencedirect.com
    Derivation of Human Trophoblast Stem Cells
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    sciencedirect.com/science/article/pii/S1934590917304563
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    Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency
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    sciencedirect.com/science/article/pii/S1535610817303483