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    Reprogramming of fibroblasts into cancer-associated fibroblasts via IGF2-mediated autophagy promotes metastasis of lung cancer cells
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    sciencedirect.com/science/article/pii/S2589004224024945
  3. Nov 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Kaempferol attenuates hyperuricemia combined with gouty arthritis via urate transporters and NLRP3/NF-κB pathway modulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC11550584/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Insulin Mediates Lipopolysaccharide-Induced Inflammatory Responses and Oxidative Stress in BV2 Microglia
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    TREM-1 mediates interaction between substantia nigra microglia and peripheral neutrophils
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    ncbi.nlm.nih.gov/pmc/articles/PMC11467918/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antagonistic roles of cGAS/STING signaling in colorectal cancer chemotherapy
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  8. Oct 2024
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    Disruption of cellular plasticity by repeat RNAs in human pancreatic cancer
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    Overproduction of Gastrointestinal 5-HT Promotes Colitis-Associated Colorectal Cancer Progression via Enhancing NLRP3 Inflammasome Activation
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    aacrjournals.org/cancerimmunolres/article/9/9/1008/666146/Overproduction-of-Gastrointestinal-5-HT-Promotes
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    Conophylline Inhibits Hepatocellular Carcinoma by Inhibiting Activated Cancer-associated Fibroblasts Through Suppression of G Protein–coupled Receptor 68
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    aacrjournals.org/mct/article/20/6/1019/673256/Conophylline-Inhibits-Hepatocellular-Carcinoma-by
  12. Sep 2024
  13. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 27 Sep 2024
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      DOI: 10.1111/bph.17320

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17320
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    A novel inhibitor of class IIa histone deacetylases attenuates collagen-induced arthritis
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    1. scibot 27 Sep 2024
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    Myeloid beta-arrestin 2 depletion attenuates metabolic dysfunction-associated steatohepatitis via the metabolic reprogramming of macrophages
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    sciencedirect.com/science/article/pii/S1550413124003620
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    Sodium Butyrate Exacerbates Parkinson’s Disease by Aggravating Neuroinflammation and Colonic Inflammation in MPTP-Induced Mice Model
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    1. scibot 25 Sep 2024
      RRID:AB_2797709

      DOI: 10.1007/s11064-020-03074-3

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    MANF ablation causes prolonged activation of the UPR without neurodegeneration in the mouse midbrain dopamine system
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      DOI: 10.1523/ENEURO.0477-19.2019

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    Silencing of TXNIP attenuates oxidative stress injury in HEI-OC1 by inhibiting the activation of NLRP3 and NF-κB
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    Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma
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    sciencedirect.com/science/article/pii/S2211124724010726
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    E3 ubiquitin ligase ANKIB1 attenuates antiviral immune responses by promoting K48-linked polyubiquitination of MAVS
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    sciencedirect.com/science/article/pii/S2211124724010386
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    CD14 is a decision-maker between Fas-mediated death and inflammation
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    sciencedirect.com/science/article/pii/S2211124724010362
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    Beyond mitochondrial transfer, cell fusion rescues metabolic dysfunction and boosts malignancy in adenoid cystic carcinoma
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    sciencedirect.com/science/article/pii/S2211124724010039
  23. Aug 2024
  24. www.sciencedirect.com www.sciencedirect.com
    Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in atypical teratoid/rhabdoid tumors
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    sciencedirect.com/science/article/pii/S266637912400421X
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    Cordycepin exhibits both antiviral and anti-inflammatory effects against dengue virus infection
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    Macrophage ILF3 promotes abdominal aortic aneurysm by inducing inflammatory imbalance in male mice
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    Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection
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  28. pubs.rsc.org pubs.rsc.org
    Hexane Insoluble Fraction from Purple Rice Extract Improves Steatohepatitis and Fibrosis via Inhibition of NF-κB and JNK Signaling
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      DOI: 10.1039/D4FO00292J

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  29. www.mdpi.com www.mdpi.com
    TCF19 Impacts a Network of Inflammatory and DNA Damage Response Genes in the Pancreatic β-Cell
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  30. Jul 2024
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    A human commensal-pathogenic fungus suppresses host immunity via targeting TBK1
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    sciencedirect.com/science/article/pii/S1931312824002622
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Parkin-regulated metabolomic change in cartilage in the treatment of osteoarthritis
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  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monoacylglycerol acyltransferase-2 inhibits colorectal carcinogenesis in APCmin+/− mice
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    Targeting type I DED interactions at the DED filament serves as a sensitive switch for cell fate decisions
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    Both enantiomers of β-aminoisobutyric acid BAIBA regulate Fgf23 via MRGPRD receptor by activating distinct signaling pathways in osteocytes
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    sciencedirect.com/science/article/pii/S2211124724007253
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The SASP factor IL-6 sustains cell-autonomous senescent cells via a cGAS-STING-NFκB intracrine senescent noncanonical pathway
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    onlinelibrary.wiley.com/doi/10.1111/acel.14258
  37. www.sciencedirect.com www.sciencedirect.com
    A new neuroprotective candidate TJ1 targeting amyloidogenesis in 5xFAD Alzheimer’s disease mice
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    sciencedirect.com/science/article/pii/S1567576924011743
  38. www.cell.com www.cell.com
    DOT1L/H3K79me2 represses HIV-1 reactivation via recruiting DCAF1
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    cell.com/cell-reports/fulltext/S2211-1247(24)00696-X
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication
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    ncbi.nlm.nih.gov/pmc/articles/PMC11233922/
  40. Jun 2024
  41. www.sciencedirect.com www.sciencedirect.com
    Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer
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    sciencedirect.com/science/article/pii/S155041312400189X
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    Monomethyl fumarate attenuates lung Ischemia/Reperfusion injury by disrupting the GAPDH/Siah1 signaling cascade
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    Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells
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    sciencedirect.com/science/article/pii/S1934590924001851
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    TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons
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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional Synergy in Human Aortic Endothelial Cells is Vulnerable to Combination p300/CBP and BET Bromodomain Inhibition
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    ncbi.nlm.nih.gov/pmc/articles/PMC11167439/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 envelope protein regulates innate immune tolerance
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    CYP7B1-mediated 25-hydroxycholesterol degradation maintains quiescence-activation balance and improves therapeutic potential of mesenchymal stem cells
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    Mycobacterial Rv1804c binds to the PEST domain of IκBα and activates macrophage-mediated proinflammatory responses
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    In vivo CRISPR knockout screen identifies p47 as a suppressor of HER2+ breast cancer metastasis by regulating NEMO trafficking and autophagy flux
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    Inhibition of mGluR5/PI3K-AKT Pathway Alleviates Alzheimer’s Disease-Like Pathology Through the Activation of Autophagy in 5XFAD Mice
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    Gut-Brain Axis Interplay via STAT3 pathway: Implications of Helicobacter pylori derived secretome on inflammation and Alzheimer's disease
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    Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress
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    Allosteric inhibitor of SHP2 enhances macrophage endocytosis and bacteria elimination by increasing caveolae activation and protects against bacterial sepsis
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    Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling
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    Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors
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    miRNA-194-3p represses NF-κB in gliomas to attenuate iPSC genes and proneural to mesenchymal transition.
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    hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50
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    Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins
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    Culin5 aggravates hypoxic pulmonary hypertension by activating TRAF6/NF-κB/HIF-1α/VEGF
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    Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis
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    Deubiquitylating Enzyme OTUB1 Facilitates Neuronal Survival After Intracerebral Hemorrhage Via Inhibiting NF-κB-triggered Apoptotic Cascades
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    The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation
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    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice
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    IRP1 Mediated Ferroptosis Reverses Temozolomide Resistance in Glioblastoma via Affecting LCN2/FPN1 Signaling Axis Depended on NFKB2
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  136. Jul 2023
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    Ketogenic diet alleviates cognitive dysfunction and neuroinflammation in APP/PS1 mice via the Nrf2/HO-1 and NF-κB signaling pathways
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    Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice
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    Caffeoylquinic acids isolated from Lonicera japonica Thunb. as TAK1 inhibitors protects against LPS plus IFN-γ-stimulated inflammation by interacting with KEAP1-regulated NRF2 activation
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    Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses
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    Statins enhances antitumor effect of oxaliplatin in KRAS-mutated colorectal cancer cells and inhibits oxaliplatin-induced neuropathy
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  183. Mar 2023
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    A high-sucrose diet exacerbates the left ventricular phenotype in a high fat-fed streptozotocin rat model of diabetic cardiomyopathy
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    Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity
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    Periostin deficiency reduces PD-1+ tumor-associated macrophage infiltration and enhances anti-PD-1 efficacy in colorectal cancer
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    Linear ubiquitination induces NEMO phase separation to activate NF-κB signaling
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    CDK1 bridges NF-κB and β-catenin signaling in response to H. pylori infection in gastric tumorigenesis
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    Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma
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    Streptolysin S targets the sodium-bicarbonate cotransporter NBCn1 to induce inflammation and cytotoxicity in human keratinocytes during Group A Streptococcal infection
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    STAT3 is activated by CTGF-mediated tumor-stroma cross talk to promote HCC progression.
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    sciencedirect.com/science/article/pii/S2352345X22001989