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    PRMT1 promotes epigenetic reprogramming associated with acquired chemoresistance in pancreatic cancer
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    Edaravone Dexborneol mitigates pathology in animal and cell culture models of Alzheimer’s disease by inhibiting neuroinflammation and neuronal necroptosis
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    Exogenous non-coding dsDNA-dependent trans-activation of phagocytes augments anti-tumor immunity
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    Conditional deletion of Zeb1 in Csf1r+ cells reduces inflammatory response of the cornea to alkali burn
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    Chang-Kang-Fang alleviates diarrhea predominant irritable bowel syndrome (IBS-D) through inhibiting TLR4/NF-κB/NLRP3 pathway
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    6-O-angeloylplenolin inhibits osteoclastogenesis in vitro via suppressing c-Src/NF-κB/NFATc1 pathways and ameliorates bone resorption in collagen-induced arthritis mouse model
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    Semaphorin3C identified as mediator of neuroinflammation and microglia polarization after spinal cord injury
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    The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia
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    SWI/SNF complex-mediated chromatin remodelling in Candida glabrata promotes immune evasion
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    CircTMEM165 facilitates endothelial repair by modulating mitochondrial fission via miR-192/SCP2 in vitro and in vivo
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    Oncostatin M signaling drives cancer-associated skeletal muscle wasting
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    Niche inflammatory signals control oscillating mammary regeneration and protect stem cells from cytotoxic stress
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    Subventricular zone stem cell niche injury is associated with intestinal perforation in preterm infants and predicts future motor impairment
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    Pooled CRISPR screening of high-content cellular phenotypes using ghost cytometry
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    Diosgenin protects against cationic bovine serum albumin-induced membranous glomerulonephritis by attenuating oxidative stress and renal inflammation via the NF-κB pathway
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    Lupenone improves motor dysfunction in spinal cord injury mice through inhibiting the inflammasome activation and pyroptosis in microglia via the nuclear factor kappa B pathway
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    Edaravone dexborneol promotes M2 microglia polarization against lipopolysaccharide-induced inflammation via suppressing TLR4/MyD88/NF-κB pathway
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    Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis
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    Iron overload in hypothalamic AgRP neurons contributes to obesity and related metabolic disorders
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    ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis
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    Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice
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    Targeting aberrant glycosylation to modulate microglial response and improve cognition in models of Alzheimer’s disease
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    The transcription factor NF-κB orchestrates nucleosome remodeling during the primary response to Toll-like receptor 4 signaling
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    HERC5-catalyzed ISGylation potentiates cGAS-mediated innate immunity
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    Maternal inflammation regulates fetal emergency myelopoiesis
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    CYP7B1-mediated 25-hydroxycholesterol degradation maintains quiescence-activation balance and improves therapeutic potential of mesenchymal stem cells
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    Mycobacterial Rv1804c binds to the PEST domain of IκBα and activates macrophage-mediated proinflammatory responses
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    In vivo CRISPR knockout screen identifies p47 as a suppressor of HER2+ breast cancer metastasis by regulating NEMO trafficking and autophagy flux
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    ATG5 attenuates inflammatory signaling in mouse embryonic stem cells to control differentiation
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    Inhibition of mGluR5/PI3K-AKT Pathway Alleviates Alzheimer’s Disease-Like Pathology Through the Activation of Autophagy in 5XFAD Mice
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    Gut-Brain Axis Interplay via STAT3 pathway: Implications of Helicobacter pylori derived secretome on inflammation and Alzheimer's disease
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    Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress
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    Allosteric inhibitor of SHP2 enhances macrophage endocytosis and bacteria elimination by increasing caveolae activation and protects against bacterial sepsis
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    The relevance between abnormally elevated serum ceramide and cognitive impairment in Alzheimer’s disease model mice and its mechanism
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  39. Jan 2024
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    MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning
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    Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling
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    Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors
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    miRNA-194-3p represses NF-κB in gliomas to attenuate iPSC genes and proneural to mesenchymal transition.
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    hRpn13 shapes the proteome and transcriptome through epigenetic factors HDAC8, PADI4, and transcription factor NF-κB p50
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  48. Dec 2023
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    NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62
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    Aedes aegypti saliva modulates inflammasome activation and facilitates flavivirus infection in vitro
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    Nanocurcumin attenuates pyroptosis and inflammation through inhibiting NF-κB/GSDMD signal in high altitude-associated acute liver injury
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    Blockade of CCR5 suppresses paclitaxel-induced peripheral neuropathic pain caused by increased deoxycholic acid
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    Transcriptomic analysis of sorted lung cells revealed a proviral activity of the NF-κB pathway toward SARS-CoV-2
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    Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins
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    Culin5 aggravates hypoxic pulmonary hypertension by activating TRAF6/NF-κB/HIF-1α/VEGF
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    MEK inhibitors increase the mortality rate in mice with LPS-induced inflammation through IL-12-NO signaling
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    Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor–Positive Breast Cancer
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    Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis
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    Neuronal AR regulates glucose homeostasis and energy expenditure in lean female mice with androgen excess
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    Deubiquitylating Enzyme OTUB1 Facilitates Neuronal Survival After Intracerebral Hemorrhage Via Inhibiting NF-κB-triggered Apoptotic Cascades
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    The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation
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    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
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    TPL2 kinase activity regulates microglial inflammatory responses and promotes neurodegeneration in tauopathy mice
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    IRP1 Mediated Ferroptosis Reverses Temozolomide Resistance in Glioblastoma via Affecting LCN2/FPN1 Signaling Axis Depended on NFKB2
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  78. Jul 2023
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    Ketogenic diet alleviates cognitive dysfunction and neuroinflammation in APP/PS1 mice via the Nrf2/HO-1 and NF-κB signaling pathways
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    NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-condensation with p62
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    PARP2 downregulation in T cells ameliorates lipopolysaccharide-induced inflammation of the large intestine
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    Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice
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    Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
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    Tissue factor is a critical regulator of radiation therapy-induced glioblastoma remodeling
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    HIV-1 Tat Upregulates TREM1 Expression in Human Microglia
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    Caffeoylquinic acids isolated from Lonicera japonica Thunb. as TAK1 inhibitors protects against LPS plus IFN-γ-stimulated inflammation by interacting with KEAP1-regulated NRF2 activation
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  130. Feb 2023
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    Beta-coronaviruses exploit cellular stress responses by modulating TFEB and TFE3 activity
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    Gestational palmitic acid suppresses embryonic GATA-binding protein 4 signaling and causes congenital heart disease
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  133. journals.lww.com journals.lww.com
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    Periostin deficiency reduces PD-1+ tumor-associated macrophage infiltration and enhances anti-PD-1 efficacy in colorectal cancer
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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Linear ubiquitination induces NEMO phase separation to activate NF-κB signaling
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  137. Jan 2023
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    CDK1 bridges NF-κB and β-catenin signaling in response to H. pylori infection in gastric tumorigenesis
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    Type I interferon/STAT1 signaling regulates UBE2M-mediated antiviral innate immunity in a negative feedback manner
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    Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes
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  143. 52.53.155.43 52.53.155.43
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    Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma
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    Exosomal miR-27b-3p secreted by visceral adipocytes contributes to endothelial inflammation and atherogenesis
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    NF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancer
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    ATP6V0D1 promotes alkaliptosis by blocking STAT3-mediated lysosomal pH homeostasis
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  148. Dec 2022
  149. www.embopress.org www.embopress.org
    DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma
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    Allicin ameliorates IMQ-induced psoriasis-like skin inflammation via disturbing the interaction of keratinocytes with IL-17A
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    Neuroprotective and Anti-Neuroinflammatory Properties of Vignae Radiatae Semen in Neuronal HT22 and Microglial BV2 Cell Lines
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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  153. Nov 2022
  154. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus
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    NF-κB-regulated VentX expression mediates tumoricidal effects of chemotherapeutics at noncytotoxic concentrations
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    Streptolysin S targets the sodium-bicarbonate cotransporter NBCn1 to induce inflammation and cytotoxicity in human keratinocytes during Group A Streptococcal infection
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    STAT3 is activated by CTGF-mediated tumor-stroma cross talk to promote HCC progression.
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    Dual anti-angiogenic and anti-metastatic activity of myriocin synergistically enhances the anti-tumor activity of cisplatin
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    The epigenetic state of IL-4-polarized macrophages enables inflammatory cistromic expansion and extended synergistic response to TLR ligands
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  162. Oct 2022
  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    COMPREHENSIVE DRUG RESPONSE PROFILING AND PAN-OMIC ANALYSIS IDENTIFIED THERAPEUTIC CANDIDATES AND PROGNOSTIC BIOMARKERS FOR ASIAN CHOLANGIOCARCINOMA
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  166. Sep 2022
  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    cGAS-STING Activation by Cytosolic Mitochondrial DNA Contributes to Podocyte Injury in Diabetic Kidney Disease
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    Obesity induces extracellular vesicle release from the endothelium as a contributor to brain damage after cerebral ischemia in rats
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    Pretreatment of the ROS Inhibitor Phenyl-N-tert-butylnitrone Alleviates Sleep Deprivation-Induced Hyperalgesia by Suppressing Microglia Activation and NLRP3 Inflammasome Activity in the Spinal Dorsal Cord
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    The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
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  171. Aug 2022
  172. www.sciencedirect.com www.sciencedirect.com
    Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade
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    Butyrate-producing Eubacterium rectale suppresses lymphomagenesis by alleviating the TNF-induced TLR4/MyD88/NF-κB axis
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    Neuroinflammatory disease disrupts the blood-CNS barrier via crosstalk between proinflammatory and endothelial-to-mesenchymal-transition signaling
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  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BCL10 mutations define distinct dependencies guiding precision therapy for DLBCL
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    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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      RRID:AB_10859369

      DOI: 10.1016/j.isci.2021.103434

      Resource: (Cell Signaling Technology Cat# 8242, RRID:AB_10859369)

      Curator: @scibot

      SciCrunch record: RRID:AB_10859369

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      RRID:AB_10859369
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    ncbi.nlm.nih.gov/pmc/articles/PMC8633968/