379 Matching Annotations
  1. Dec 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Nuclear respiratory factor-1 negatively regulates TGF-β1 and attenuates pulmonary fibrosis
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    sciencedirect.com/science/article/pii/S2589004221015066
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    Toxoplasma gondii SAG1 Targeting Host Cell S100A6 for Parasite Invasion and Host Immunity
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    sciencedirect.com/science/article/pii/S2589004221014851
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    CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism
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    sciencedirect.com/science/article/pii/S2589004221015091
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8633968/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism
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      DOI: 10.7554/eLife.73215

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    ncbi.nlm.nih.gov/pmc/articles/PMC8635982/
  7. www.sciencedirect.com www.sciencedirect.com
    Phospholipid nanoparticles: Therapeutic potentials against atherosclerosis via reducing cholesterol crystals and inhibiting inflammation
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    sciencedirect.com/science/article/pii/S2352396421005193
  8. www.nature.com www.nature.com
    Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer
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      DOI: 10.1038/s42003-021-02842-3

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    nature.com/articles/s42003-021-02842-3
  9. Nov 2021
  10. www.sciencedirect.com www.sciencedirect.com
    LARP7 ameliorates cellular senescence and aging by allosterically enhancing SIRT1 deacetylase activity
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    sciencedirect.com/science/article/pii/S2211124721015205
  11. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The multicellular signalling network of ovarian cancer metastases
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      DOI: 10.1002/ctm2.633

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    onlinelibrary.wiley.com/doi/10.1002/ctm2.633
  12. www.sciencedirect.com www.sciencedirect.com
    m6A mRNA methylation-directed myeloid cell activation controls progression of NAFLD and obesity
    1
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    sciencedirect.com/science/article/pii/S2211124721014479
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetyl-CoA derived from hepatic mitochondrial fatty acid β-oxidation aggravates inflammation by enhancing p65 acetylation
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    1. scibot 09 Nov 2021
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    ncbi.nlm.nih.gov/pmc/articles/PMC8551082/
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    Resolving macrophage polarization through distinct Ca2+ entry channel that maintains intracellular signaling and mitochondrial bioenergetics
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    sciencedirect.com/science/article/pii/S2589004221013080
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    IRF3-binding lncRNA-ISIR strengthens interferon production in viral infection and autoinflammation
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    sciencedirect.com/science/article/pii/S2211124721013991
  16. Oct 2021
  17. journals.physiology.org journals.physiology.org
    Vitamin D/VDR signaling inhibits colitis by suppressing HIF-1α activation in colonic epithelial cells
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    1. scibot 20 Oct 2021
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      DOI: 10.1152/ajpgi.00061.2021

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    journals.physiology.org/doi/abs/10.1152/ajpgi.00061.2021
  18. www.sciencedirect.com www.sciencedirect.com
    Regulation of CYLD activity and specificity by phosphorylation and ubiquitin-binding CAP-Gly domains
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    sciencedirect.com/science/article/pii/S2211124721012316
  19. Sep 2021
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    Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming
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    sciencedirect.com/science/article/pii/S1550413121004216
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    AIM/CD5L attenuates DAMPs in the injured brain and thereby ameliorates ischemic stroke
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    sciencedirect.com/science/article/pii/S2211124721011402
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    SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages
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    sciencedirect.com/science/article/pii/S2211124721011062
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    Activating a collaborative innate-adaptive immune response to control metastasis
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    sciencedirect.com/science/article/pii/S1535610821004451
  24. Aug 2021
  25. www.sciencedirect.com www.sciencedirect.com
    Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy
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      DOI: 10.1016/j.cell.2021.07.020

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    sciencedirect.com/science/article/pii/S0092867421008795
  26. www.immunohorizons.org www.immunohorizons.org
    3-Hydroxykynurenine Regulates Lipopolysaccharide-Stimulated IL-6 Production and Protects against Endotoxic Shock in Mice
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      DOI: 10.4049/immunohorizons.2100028

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    immunohorizons.org/content/5/6/523
  27. academic.oup.com academic.oup.com
    Differential Actions of Estrogen Receptor α and β via Non-Genomic Signaling in Human Prostate Stem and Progenitor Cells
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    1. scibot 14 Aug 2021
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      DOI: 10.1210/en.2019-00177

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    academic.oup.com/endo/article/160/11/2692/5551999
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD36 initiates the secretory phenotype during the establishment of cellular senescence
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      DOI: 10.15252/embr.201745274

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    ncbi.nlm.nih.gov/pmc/articles/PMC5989758/
  29. embor.embopress.org embor.embopress.org
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  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5711380/
  31. elifesciences.org elifesciences.org
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      DOI: 10.7554/eLife.22871

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  32. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S2211124718316462
  33. www.frontiersin.org www.frontiersin.org
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      DOI: 10.3389/fimmu.2018.01425

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    frontiersin.org/article/10.3389/fimmu.2018.01425/full
  34. academic.oup.com academic.oup.com
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    academic.oup.com/endo/article/158/10/3592/4056264
  35. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Spinal Nrf2 translocation may inhibit neuronal NF-κB activation and alleviate allodynia in a rat model of bone cancer pain
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15468
  36. www.sciencedirect.com www.sciencedirect.com
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    Reshaping of the Dendritic Cell Chromatin Landscape and Interferon Pathways during HIV Infection
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      DOI: 10.1016/j.chom.2018.01.012

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    sciencedirect.com/science/article/pii/S1931312818300477
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5659692/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Plasminogen Activator Inhibitor-1 Promotes the Recruitment and Polarization of Macrophages in Cancer
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    sciencedirect.com/science/article/pii/S2211124718316863
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    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
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    sciencedirect.com/science/article/pii/S1931312818305584
  43. Jul 2021
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.7554/eLife.24425

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    ncbi.nlm.nih.gov/pmc/articles/PMC5484619/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6205837/
  46. mbio.asm.org mbio.asm.org
    TREM-1 Protects HIV-1-Infected Macrophages from Apoptosis through Maintenance of Mitochondrial Function
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      DOI: 10.1128/mBio.02638-19

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  47. www.jbc.org www.jbc.org
    Large-conductance calcium-activated potassium channels mediate lipopolysaccharide-induced activation of murine microglia
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      DOI: 10.1074/jbc.RA118.006425

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  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Curcumin attenuates proangiogenic and proinflammatory factors in human eutopic endometrial stromal cells through the NF‐κB signaling pathway
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      DOI: 10.1002/jcp.27360

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  59. Jun 2021
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    Table 2 | Saussureae Radix Attenuates Neuroinflammation in LPS-Stimulated Mouse BV2 Microglia via HO-1/Nrf-2 Induction and Inflammatory Pathway Inhibition
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  67. May 2021
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    The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation
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    Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling
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    Inhibition of fibroblast IL-6 production by ACKR4 deletion alleviates cardiac remodeling after myocardial infarction
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  86. Mar 2021
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    Proteogenomics of glioblastoma associates molecular patterns with survival
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  89. Feb 2021
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    Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies
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    Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation via HMGB1/TLR4/NF‐κB and TNF‐α/TNFR1/NF‐κB pathways
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    The enhancer RNA lnc-SLC4A1-1 epigenetically regulates unexplained recurrent pregnancy loss (URPL) by activating CXCL8 and NF-kB pathway
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    Muscone suppresses inflammatory responses and neuronal damage in a rat model of cervical spondylotic myelopathy by regulating Drp1‐dependent mitochondrial fission
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  95. www.liebertpub.com www.liebertpub.com
    NF-κB/Cartilage Acidic Protein 1 Promotes Ultraviolet B Irradiation-Induced Apoptosis of Human Lens Epithelial Cells
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    Iron Potentiates Microglial Interleukin‐1β Secretion Induced by Amyloid‐β
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  97. Jan 2021
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    Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation
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    A Nuclear Export Signal Is Required for cGAS to Sense Cytosolic DNA
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  102. Nov 2020
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  104. www.frontiersin.org www.frontiersin.org
    Polyunsaturated Fatty Acids Influence LPS-Induced Inflammation of Fish Macrophages Through Differential Modulation of Pathogen Recognition and p38 MAPK/NF-κB Signaling
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  105. Oct 2020
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-Transcriptional and Translational Function of Canonical NF-κB Signaling in Activating ERK1/2 in IL-1β-Induced COX-2 Expression in Synovial Fibroblasts
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  107. link.springer.com link.springer.com
    Uric acid drives intestinal barrier dysfunction through TSPO-mediated NLRP3 inflammasome activation
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  108. link.springer.com link.springer.com
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      NFκB (p65)

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  109. Sep 2020
  110. onlinelibrary.wiley.com onlinelibrary.wiley.com
    microRNA‐9‐5p alleviates blood‐brain barrier damage and neuroinflammation after traumatic brain injury
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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  112. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  113. www.sciencedirect.com www.sciencedirect.com
    Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1
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  114. www.sciencedirect.com www.sciencedirect.com
    The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis
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  115. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
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  116. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Enhanced Akt/GSK‐3β/CREB signaling mediates the anti‐inflammatory actions of mGluR5 positive allosteric modulators in microglia and following traumatic brain injury in male mice
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    Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity
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  118. www.cell.com www.cell.com
    PRMT1 Is Recruited via DNA-PK to Chromatin Where It Sustains the Senescence-Associated Secretory Phenotype in Response to Cisplatin
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    Loratadine, an antihistamine drug, exhibits anti-inflammatory activity through suppression of the NF-kB pathway
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    Glioblastoma Cell Resistance to EGFR and MET Inhibition Can Be Overcome via Blockade of FGFR-SPRY2 Bypass Signaling
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    Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells
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    Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
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    A novel compound DBZ ameliorates neuroinflammation in LPS-stimulated microglia and ischemic stroke rats: Role of Akt(Ser473)/GSK3β(Ser9)-mediated Nrf2 activation
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  126. www.cell.com www.cell.com
    Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia
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    Inactivation of the tyrosine phosphatase SHP-2 drives vascular dysfunction in Sepsis
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      rabbit NF-κB p65 (D14E12) XP™

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    Lysophosphatidic Acid-Mediated GPR35 Signaling in CX3CR1+ Macrophages Regulates Intestinal Homeostasis
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  129. www.liebertpub.com www.liebertpub.com
    NF-κB/Cartilage Acidic Protein 1 Promotes Ultraviolet B Irradiation-Induced Apoptosis of Human Lens Epithelial Cells | DNA and Cell Biology
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  130. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    IKKε and TBK1 in diffuse large B‐cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF‐κB and IL‐10 signalling
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      RELA

      DOI: 10.1111/jcmm.15774

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  131. jvi.asm.org jvi.asm.org
    Middle East respiratory syndrome coronavirus nucleocapsid protein suppresses type I and type III interferon induction by targeting RIG-I signaling
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      NF-κB p65

      DOI: 10.1128/JVI.00099-20

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  132. www.jci.org www.jci.org
    Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT
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      anti–NF-κB p65

      DOI: 10.1172/JCI128994

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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Vitamin D Supplementation Rescues Aberrant NF-κB Pathway Activation and Partially Ameliorates Rett Syndrome Phenotypes in Mecp2 Mutant Mice
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      RRID:AB_10859369

      DOI: 10.1523/ENEURO.0167-20.2020

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  134. Jan 2020
  135. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Decreased levels of constitutive proteasomes in experimental autoimmune encephalomyelitis may be caused by a combination of subunit displacement and reduced Nfe2l1 expression
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      AB_10859369

      DOI: 10.1111/jnc.14912

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    Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion
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    Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells
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    Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation
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    Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress
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    CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness
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    Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection
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  178. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis
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    IL-1β Inhibits Connexin 43 and Disrupts Decidualization of Human Endometrial Stromal Cells Through ERK1/2 and p38 MAP Kinase
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  182. Nov 2017
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    Dipeptidyl Peptidase-4 Inhibition With Saxagliptin Ameliorates Angiotensin II–Induced Cardiac Diastolic Dysfunction in Male Mice
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  184. www.sciencedirect.com www.sciencedirect.com
    Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity
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  185. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Protein kinase D exerts neuroprotective functions during oxidative stress via Nuclear Factor kappaB‐independent signaling pathways
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    Anaphylatoxin C5a Regulates 6-Sulfo-LacNAc Dendritic Cell Function in Human through Crosstalk with Toll-Like Receptor-Induced CREB Signaling
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  187. journal.frontiersin.org journal.frontiersin.org
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  188. www.jneurosci.org www.jneurosci.org
    An Agonist of the Protective Factor SIRT1 Improves Functional Recovery and Promotes Neuronal Survival by Attenuating Inflammation after Spinal Cord Injury
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  189. elifesciences.org elifesciences.org
    Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses
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    The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior
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    Astrocytic Process Plasticity and IKKβ/NF-κB in Central Control of Blood Glucose, Blood Pressure, and Body Weight
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  192. elifesciences.org elifesciences.org
    The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration
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    Lipid Desaturation Is a Metabolic Marker and Therapeutic Target of Ovarian Cancer Stem Cells
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  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes
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