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  1. Last 7 days
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    MicroRNA-19b exacerbates systemic sclerosis through promoting Th9 cells
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  3. Jun 2024
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    The phosphorylation-deubiquitination positive feedback loop of the CHK2-USP7 axis stabilizes p53 under oxidative stress
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    The HRD1-SEL1L ubiquitin ligase regulates stress granule homeostasis in couple with distinctive signaling branches of ER stress
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    sciencedirect.com/science/article/pii/S2589004224014214
  6. May 2024
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    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
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    Ubiquitin-mediated regulation of APE2 protein abundance
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    sciencedirect.com/science/article/pii/S0021925824018386
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    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
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    ncbi.nlm.nih.gov/pmc/articles/PMC11068011/
  10. Apr 2024
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    O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
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    ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection
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  13. Mar 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation
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      DOI: 10.7554/eLife.87386

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    ncbi.nlm.nih.gov/pmc/articles/PMC10942603/
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    Aging-induced tRNAGlu-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization
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    sciencedirect.com/science/article/pii/S1550413124000573
  16. Feb 2024
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    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
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  18. Dec 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62
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    De novo NAD+ synthesis contributes to CD8+ T cell metabolic fitness and antitumor function
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  21. Nov 2023
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    RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks
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    FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation
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  24. Oct 2023
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    MLKL regulates Cx43 ubiquitinational degradation and mediates neuronal necroptosis in ipsilateral thalamus after focal cortical infarction
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      DOI: 10.1186/s13041-023-01064-4

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    PAICS ubiquitination recruits UBAP2 to trigger phase separation for purinosome assembly
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    sciencedirect.com/science/article/pii/S1097276523007554
  27. Sep 2023
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    TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation
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  29. Aug 2023
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    Molecular mechanism for activation of the 26S proteasome by ZFAND5
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  31. Jul 2023
  32. 52.53.155.43 52.53.155.43
    NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-condensation with p62
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      DOI: 10.1101/2023.06.05.543428

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  33. Jun 2023
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    UBE2M-mediated neddylation of TRIM21 regulates obesity-induced inflammation and metabolic disorders
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  35. May 2023
  36. www.nature.com www.nature.com
    Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance
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    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
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      DOI: 10.1002/cac2.12332

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  38. Apr 2023
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    PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1
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  40. Feb 2023
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    TRIM21-dependent target protein ubiquitination mediates cell-free Trim-Away
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    sciencedirect.com/science/article/pii/S2211124723001365
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    RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex
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  43. Jan 2023
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    Type I interferon/STAT1 signaling regulates UBE2M-mediated antiviral innate immunity in a negative feedback manner
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  45. Dec 2022
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    Excessive proteostasis contributes to pathology in fragile X syndrome
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      DOI: 10.1016/j.neuron.2022.11.012

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    sciencedirect.com/science/article/pii/S0896627322010352
  47. Nov 2022
  48. www.embopress.org www.embopress.org
    LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus
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      DOI: 10.15252/embj.2022112006

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    embopress.org/doi/10.15252/embj.2022112006
  49. Jul 2022
  50. www.nature.com www.nature.com
    Deubiquitinase OTUD6A promotes breast cancer progression by increasing TopBP1 stability and rendering tumor cells resistant to DNA-damaging therapy
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      DOI: 10.1038/s41418-022-01036-6

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    nature.com/articles/s41418-022-01036-6
  51. Mar 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Delicate regulation of IL-1β-mediated inflammation by cyclophilin A
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    sciencedirect.com/science/article/pii/S2211124722002492
  53. elifesciences.org elifesciences.org
    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
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      DOI: 10.7554/eLife.73150

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    elifesciences.org/articles/73150
  54. www.sciencedirect.com www.sciencedirect.com
    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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      Cell Signaling Tehnology cat# 8081

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  55. Feb 2022
  56. www.sciencedirect.com www.sciencedirect.com
    A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
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    sciencedirect.com/science/article/pii/S1097276522000879
  57. Dec 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Translocation of polyubiquitinated protein substrates by the hexameric Cdc48 ATPase
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  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation
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      DOI: 10.3389/fphys.2021.779547

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    ncbi.nlm.nih.gov/pmc/articles/PMC8669767/
  60. Aug 2021
  61. www.sciencedirect.com www.sciencedirect.com
    Feedback repression of PPARα signaling by Let-7 microRNA
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      DOI: 10.1016/j.celrep.2021.109506

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    sciencedirect.com/science/article/pii/S2211124721009360
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    Untitled document
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      DOI: 10.1016/j.celrep.2019.02.067

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    sciencedirect.com/science/article/pii/S2211124719302463
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    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
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      RRID:AB_10859893

      DOI: 10.1016/j.chom.2018.11.001

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    sciencedirect.com/science/article/pii/S1931312818305584
  64. Jun 2021
  65. www.cell.com www.cell.com
    Arginine monomethylation by PRMT7 controls MAVS-mediated antiviral innate immunity
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      DOI: 10.1016/j.molcel.2021.06.004

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00451-2
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    Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation
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      RRID:AB_10859893

      DOI: 10.1016/j.celrep.2021.109272

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    sciencedirect.com/science/article/pii/S2211124721006392
  67. May 2021
  68. www.sciencedirect.com www.sciencedirect.com
    Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation
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    1. scibot 07 May 2021
      RRID:AB_10859893

      DOI: 10.1016/j.molcel.2020.10.017

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    sciencedirect.com/science/article/pii/S1097276520307243
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    A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation
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    1. scibot 07 May 2021
      RRID:AB_10859893

      DOI: 10.1016/j.immuni.2020.11.020

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    sciencedirect.com/science/article/pii/S1074761320305070
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    Proteasome stress in skeletal muscle mounts a long-range protective response that delays retinal and brain aging
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      DOI: 10.1016/j.cmet.2021.03.005

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    sciencedirect.com/science/article/pii/S1550413121001121
  71. Nov 2020
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of ubiquitin Ser57 kinases regulating the oxidative stress response in yeast
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      DOI: 10.7554/eLife.58155

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  73. Sep 2020
  74. www.sciencedirect.com www.sciencedirect.com
    Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer
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      RRID:AB_10859893

      DOI: 10.1016/j.celrep.2020.107745

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    Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer
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      RRID:AB_10859893

      DOI: 10.1016/j.ccell.2020.02.003

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    Shifts in Ribosome Engagement Impact Key Gene Sets in Neurodevelopment and Ubiquitination in Rett Syndrome
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      DOI: 10.1016/j.celrep.2020.02.107

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    sciencedirect.com/science/article/pii/S2211124720302886
  77. Jan 2020
  78. www.sciencedirect.com www.sciencedirect.com
    Targeting Degradation of the Transcription Factor C/EBPβ Reduces Lung Fibrosis by Restoring Activity of the Ubiquitin-Editing Enzyme A20 in Macrophages
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    1. scibot 13 Jan 2020
      RRID:AB_10859893

      DOI: 10.1016/j.immuni.2019.06.014

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  79. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_10859893

      DOI: 10.1016/j.celrep.2019.01.072

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    sciencedirect.com/science/article/pii/S2211124719301019
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    Iruka Eliminates Dysfunctional Argonaute by Selective Ubiquitination of Its Empty State
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    1. scibot 12 Jan 2020
      RRID:AB_10859893

      DOI: 10.1016/j.molcel.2018.10.033

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    sciencedirect.com/science/article/pii/S1097276518308931