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Evaluation of anti-tumor drugs by simulating physiological absorption and metabolism with a multi-organoid system

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  DOI: 10.1016/j.cels.2026.101734
  
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sciencedirect.com/science/article/pii/S2405471226002164
Aug 2026
journals.physiology.org journals.physiology.org

Therapeutic zinc targets dysregulated GC-C signaling and restores ileal defects in a preclinical model of familial diarrheal disease

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1. scibot 11 Aug 2026
  
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  DOI: 10.1152/ajpgi.00049.2026
  
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2. scibot 01 Aug 2026
  
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  DOI: 10.1152/ajpgi.00049.2026
  
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journals.physiology.org/doi/full/10.1152/ajpgi.00049.2026
journals.physiology.org journals.physiology.org

Therapeutic zinc targets dysregulated GC-C signaling and restores ileal defects in a preclinical model of familial diarrheal disease

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journals.physiology.org/doi/10.1152/ajpgi.00049.2026
Jul 2026
54.241.53.176 54.241.53.176

bose-et-al-2026-therapeutic-zinc-targets-dysregulated-gc-c-signaling-and-restores-ileal-defects-in-a-preclinical-model-html.html

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1. scibot 02 Jul 2026
  
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  DOI: 10.6084/m9.figshare.32306769
  
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54.241.53.176/e42851046a96e5aa0aecb071a4888a4d468522ed/bose-et-al-2026-therapeutic-zinc-targets-dysregulated-gc-c-signaling-and-restores-ileal-defects-in-a-preclinical-model-html.html
Jun 2026
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A progenitor cell population contributes to prenatal injury repair and neonatal antimicrobial defense in the small intestine

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1. scibot 05 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117503
  
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sciencedirect.com/science/article/pii/S2211124726005814
May 2026
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eIF4G2-mediated selective translation of chromatin regulators safeguards adult intestinal stem cell identity and differentiation

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1. scibot 01 May 2026
  
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  DOI: 10.1016/j.stem.2026.04.006
  
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sciencedirect.com/science/article/pii/S1934590926001463
Apr 2026
journals.sagepub.com journals.sagepub.com

Clostridium butyricum Restores Intestinal Barrier Integrity via the IL-22/Reg3 Pathway Following Traumatic Brain Injury in Mice

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1. scibot 24 Apr 2026
  
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  DOI: 10.1177/08977151251367404
  
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journals.sagepub.com/doi/10.1177/08977151251367404
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Metabolic stress sensing by epithelial RXRα links westernization of diet with Crohn’s disease

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1. scibot 01 Apr 2026
  
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  DOI: 10.1016/j.cmet.2025.11.008
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13034575/
Nov 2025
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Paneth-like transition drives resistance to dual targeting of KRAS and EGFR in colorectal cancer

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1. scibot 15 Nov 2025
  
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sciencedirect.com/science/article/pii/S1535610825004519
Oct 2025
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The E3 ligase RNF32 controls the IκB kinase complex and NF-κB signaling in intestinal stem cells

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1. scibot 30 Oct 2025
  
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  DOI: 10.1016/j.molcel.2025.10.005
  
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sciencedirect.com/science/article/pii/S1097276525008226
Sep 2025
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Targeting lysozyme 2 in endocardium promotes rapid recovery by modulating remote injury signals

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1. scibot 18 Sep 2025
  
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  DOI: 10.1016/j.stem.2025.08.015
  
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sciencedirect.com/science/article/pii/S1934590925003303
www.liebertpub.com www.liebertpub.com

Clostridium butyricum Restores Intestinal Barrier Integrity via the IL-22/Reg3 Pathway Following Traumatic Brain Injury in Mice

1
1. scibot 03 Sep 2025
  
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  DOI: 10.https://home.liebertpub.com/neu
  
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liebertpub.com/doi/10.1177/08977151251367404
Jul 2025
www.embopress.org www.embopress.org

Genetic disruption of the circadian gene Bmal1 in the intestinal epithelium reduces colonic inflammation

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1. scibot 17 Jul 2025
  
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  DOI: 10.1038/s44319-025-00464-y
  
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embopress.org/doi/full/10.1038/s44319-025-00464-y
Feb 2025
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The balance between IFN-γ and ERK/MAPK signaling activities ensures lifelong maintenance of intestinal stem cells

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1. scibot 14 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115286
  
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sciencedirect.com/science/article/pii/S2211124725000579
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Alterations in Ileal Secretory Cells of The DSS-Induced Colitis Model Mice

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1. scibot 24 Jan 2025
  
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  DOI: 10.1267/ahc.24-00049
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11703563/
Dec 2024
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Frizzled5 controls murine intestinal epithelial cell plasticity through organization of chromatin accessibility

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1. scibot 06 Dec 2024
  
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  DOI: 10.1016/j.devcel.2024.10.021
  
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sciencedirect.com/science/article/pii/S1534580724006610
Jul 2024
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The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells

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1. scibot 23 Jul 2024
  
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  DOI: 10.1016/j.devcel.2024.06.001
  
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sciencedirect.com/science/article/pii/S1534580724003794
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Cbl and Cbl-b ubiquitin ligases are essential for intestinal epithelial stem cell maintenance

1
1. scibot 19 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.109912
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11225835/
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An immunohistochemical atlas of necroptotic pathway expression

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1. scibot 18 Jul 2024
  
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  DOI: 10.1038/s44321-024-00074-6
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11250867/
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Construction of multilayered small intestine-like tissue by reproducing interstitial flow

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1. scibot 12 Jul 2024
  
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  DOI: 10.1016/j.stem.2024.06.012
  
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sciencedirect.com/science/article/pii/S1934590924002200
May 2024
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Enterococcus-derived tyramine hijacks α2A-adrenergic receptor in intestinal stem cells to exacerbate colitis

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1. scibot 24 May 2024
  
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  DOI: 10.1016/j.chom.2024.04.020
  
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sciencedirect.com/science/article/pii/S1931312824001409
Nov 2023
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Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.isci.2023.108399
  
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sciencedirect.com/science/article/pii/S2589004223024768
www.biorxiv.org www.biorxiv.org

An immunohistochemical atlas of necroptotic pathway expression

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1. scibot 10 Nov 2023
  
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  RRID:AB_10861277
  
  DOI: 10.1101/2023.10.31.565039
  
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biorxiv.org/content/10.1101/2023.10.31.565039v1
Oct 2023
link.springer.com link.springer.com

Itaconate inhibits SYK through alkylation and suppresses inflammation against hvKP induced intestinal dysbiosis

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1. scibot 31 Oct 2023
  
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  RRID:AB_10861277
  
  DOI: 10.1007/s00018-023-04971-w
  
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link.springer.com/article/10.1007/s00018-023-04971-w
Sep 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Innate Mechanism of Mucosal Barrier Erosion in the Pathogenesis of Acquired Colitis

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1. scibot 28 Sep 2023
  
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  DOI: 10.1016/j.isci.2023.107883
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10518488/
Aug 2023
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Distinct molecular profiles of skull bone marrow in health and neurological disorders

2
1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.cell.2023.07.009
  
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2. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.cell.2023.07.009
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10443631/
Sep 2022
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Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal

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  DOI: 10.1016/j.stem.2022.08.008
  
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sciencedirect.com/science/article/pii/S1934590922003447
Apr 2022
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High-fat diet disrupts REG3γ and gut microbial rhythms promoting metabolic dysfunction

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1. scibot 21 Apr 2022
  
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  DOI: 10.1016/j.chom.2022.03.030
  
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sciencedirect.com/science/article/pii/S1931312822001603
Jan 2022
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Adaptive differentiation promotes intestinal villus recovery

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  DOI: 10.1016/j.devcel.2021.12.012
  
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sciencedirect.com/science/article/abs/pii/S1534580721010327
Nov 2021
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Insular cortex neurons encode and retrieve specific immune responses

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1. scibot 09 Nov 2021
  
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  DOI: 10.1016/j.cell.2021.10.013
  
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sciencedirect.com/science/article/pii/S009286742101223X
Sep 2021
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Distinct human Langerhans cell subsets orchestrate reciprocal functions and require different developmental regulation

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1. scibot 11 Sep 2021
  
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  DOI: 10.1016/j.immuni.2021.08.012
  
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sciencedirect.com/science/article/pii/S1074761321003447
Jul 2021
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Lysozyme Counteracts β-Lactam Antibiotics by Promoting the Emergence of L-Form Bacteria

2
1. scibot 29 Jul 2021
  
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  RRID:AB_10861277
  
  DOI: 10.1016/j.cell.2018.01.021
  
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2. scibot 29 Jul 2021
  
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  RRID:AB_10861277
  
  DOI: 10.1016/j.cell.2018.01.021
  
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  Curator: @evieth
  
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  RRIDCUR:Validated RRID:AB_10861277
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sciencedirect.com/science/article/pii/S0092867418300588
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Club cells form lung adenocarcinomas and maintain the alveoli of adult mice

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1. scibot 28 Jul 2021
  
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  RRID:AB_10861277
  
  DOI: 10.7554/eLife.45571
  
  Resource: (Abcam Cat# ab108508, RRID:AB_10861277)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6606035/
Jan 2020
elifesciences.org elifesciences.org

Mutationally-activated PI3’-kinase-α promotes de-differentiation of lung tumors initiated by the BRAFV600E oncoprotein kinase

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1. scibot 13 Jan 2020
  
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  RRID:AB_10861277
  
  DOI: 10.7554/eLife.43668
  
  Resource: (Abcam Cat# ab108508, RRID:AB_10861277)
  
  Curator: @Naa003
  
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elifesciences.org/articles/43668
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Gut microbiota from colorectal cancer patients enhances the progression of intestinal adenoma in Apcmin/+ mice

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1. scibot 13 Jan 2020
  
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  RRID:AB_10861277
  
  DOI: 10.1016/j.ebiom.2019.09.021
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2352396419306255
Nov 2018
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PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and Tumorigenesis

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1. scibot 05 Nov 2018
  
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  RRID:AB_10861277
  
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sciencedirect.com/science/article/pii/S1534580718301059
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Fiber-Mediated Nourishment of Gut Microbiota Protects against Diet-Induced Obesity by Restoring IL-22-Mediated Colonic Health

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1. scibot 05 Nov 2018
  
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  RRID:AB_10861277
  
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sciencedirect.com/science/article/pii/S1931312817304973
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Unsupervised Trajectory Analysis of Single-Cell RNA-Seq and Imaging Data Reveals Alternative Tuft Cell Origins in the Gut

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1. scibot 05 Nov 2018
  
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  AB_10861277
  
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  (Abcam Cat# ab108508, RRID:AB_10861277)
  
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sciencedirect.com/science/article/pii/S2405471217304490