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Epigenomic profiling of neuroendocrine lung cancers identifies a classical-neuroendocrine ASCL1/NKX2-1 subtype and a SOX11-associated differentiation axis linked to reduced immunogenicity

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1. scibot 19 May 2026
  
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  DOI: 10.1016/j.lungcan.2026.109464
  
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sciencedirect.com/science/article/pii/S0169500226005258
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Reconstructing epigenomic dynamics through a single-cell multi-epigenome data integration framework

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  DOI: 10.1038/s41467-025-67016-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12711870/
Aug 2025
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Androgen receptor–mediated assisted loading of the glucocorticoid receptor modulates transcriptional responses in prostate cancer cells

1
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  DOI: 10.1101/gr.280224.124
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12315708/
Dec 2024
www.cell.com www.cell.com

EOMES establishes mesoderm and endoderm differentiation potential through SWI/SNF-mediated global enhancer remodeling

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1. scibot 12 Dec 2024
  
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  DOI: 10.1016/j.devcel.2024.11.014
  
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cell.com/developmental-cell/fulltext/S1534-5807(24)00696-8
Jul 2024
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Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer

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sciencedirect.com/science/article/pii/S153561082400237X
Jun 2024
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CUX1 regulates human hematopoietic stem cell chromatin accessibility via the BAF complex

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  DOI: 10.1016/j.celrep.2024.114227
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11163479/
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Collaboration between distinct SWI/SNF chromatin remodeling complexes directs enhancer selection and activation of macrophage inflammatory genes

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sciencedirect.com/science/article/pii/S1074761324002620
May 2024
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ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity

1
1. scibot 21 May 2024
  
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  DOI: 10.1016/j.cell.2024.04.025
  
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sciencedirect.com/science/article/pii/S0092867424004513
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Novel therapeutic strategies targeting bypass pathways and mitochondrial dysfunction to combat resistance to RET inhibitors in NSCLC

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1. scibot 21 May 2024
  
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  DOI: 10.1016/j.bbadis.2024.167249
  
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sciencedirect.com/science/article/pii/S0925443924002382
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Molecular and pathological characterization of YAP1-expressing small cell lung cancer cell lines leads to reclassification as SMARCA4-deficient malignancies

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  DOI: 10.1158/1078-0432.CCR-23-2360
  
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aacrjournals.org/clincancerres/article/30/9/1846/743134/Molecular-and-Pathologic-Characterization-of-YAP1
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SMARCA4 loss and mutated β-catenin induce proliferative lesions in the murine embryonic cerebellum

1
1. scibot 03 May 2024
  
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  DOI: 10.1523/JNEUROSCI.1605-23.2024
  
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jneurosci.org/content/44/15/e1605232024
Apr 2024
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SP6 controls human cytotrophoblast fate decisions and trophoblast stem cell establishment by targeting MSX2 regulatory elements

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1. scibot 09 Apr 2024
  
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sciencedirect.com/science/article/pii/S153458072400193X
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Enhancer switching in cell lineage priming is linked to eRNA, Brg1’s AT-hook, and SWI/SNF recruitment

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1. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.molcel.2024.03.013
  
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sciencedirect.com/science/article/pii/S1097276524002235
Mar 2024
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SMARCA4 is a haploinsufficient B cell lymphoma tumor suppressor that fine-tunes centrocyte cell fate decisions

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1. scibot 08 Mar 2024
  
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  DOI: 10.1016/j.ccell.2024.02.011
  
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The transcription factor NF-κB orchestrates nucleosome remodeling during the primary response to Toll-like receptor 4 signaling

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1. scibot 05 Mar 2024
  
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  DOI: 10.1016/j.immuni.2024.02.004
  
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sciencedirect.com/science/article/pii/S1074761324000803
Feb 2024
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d1-html.html

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1. scibot 29 Feb 2024
  
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  DOI: 10.1158/1078-0432.ccr-23-2360
  
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52.53.155.43/9d9c84a50a37d03d2f105a9516b773f31c793012/d1-html.html
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JNEUROSCI.1605-23.2024.full-html.html

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1. scibot 29 Feb 2024
  
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  DOI: 10.1523/jneurosci.1605-23.2024
  
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2. scibot 22 Feb 2024
  
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52.53.155.43/a2ff2f36d75df7a296c08e6dbda516d47b790121/JNEUROSCI.1605-23.2024.full (1)-html.html
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BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or Menin inhibitor

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  DOI: 10.1101/2023.09.28.560054
  
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biorxiv.org/content/10.1101/2023.09.28.560054v1
Nov 2023
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Global identification of SWI/SNF targets reveals compensation by EP400

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sciencedirect.com/science/article/pii/S0092867423010887
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MYC overexpression and SMARCA4 loss cooperate to drive medulloblastoma formation in mice

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  DOI: 10.1186/s40478-023-01654-2
  
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link.springer.com/article/10.1186/s40478-023-01654-2
Sep 2023
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Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis

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1. scibot 30 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113171
  
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sciencedirect.com/science/article/pii/S221112472301183X
Jun 2023
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Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer

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  DOI: 10.1016/j.ccell.2023.05.016
  
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Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation

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1. scibot 07 Jun 2023
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10501989/
Dec 2022
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BAF complex maintains glioma stem cells in pediatric H3K27M-glioma

1
1. scibot 03 Dec 2022
  
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  DOI: 10.1158/2159-8290.CD-21-1491
  
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aacrjournals.org/cancerdiscovery/article/12/12/2880/711164/BAF-Complex-Maintains-Glioma-Stem-Cells-in
Oct 2022
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Sensitive image-based chromatin binding assays using inducible ERα to rapidly characterize estrogenic chemicals and mixtures

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1. scibot 14 Oct 2022
  
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  DOI: 10.1016/j.isci.2022.105200
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9550643/
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A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo

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  DOI: 10.1038/s41467-022-33430-6
  
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nature.com/articles/s41467-022-33430-6
Aug 2022
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Smarca4 inactivation promotes lineage-specific transformation and early metastatic features in the lung

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  DOI: 10.1158/2159-8290.CD-21-0248
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8831463/
Apr 2022
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Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma

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  DOI: 10.1016/j.celrep.2022.110637
  
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sciencedirect.com/science/article/pii/S2211124722003898
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The FUS::DDIT3 fusion oncoprotein inhibits BAF complex targeting and activity in myxoid liposarcoma

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  DOI: 10.1016/j.molcel.2022.03.019
  
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sciencedirect.com/science/article/pii/S109727652200257X
Dec 2021
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IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer

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1. scibot 22 Dec 2021
  
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  DOI: 10.1016/j.celrep.2021.110138
  
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sciencedirect.com/science/article/pii/S221112472101634X
Nov 2021
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Developmental defects in Huntington’s disease show that axonal growth and microtubule reorganization require NUMA1

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1. scibot 18 Nov 2021
  
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  DOI: 10.1016/j.neuron.2021.10.033
  
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sciencedirect.com/science/article/pii/S0896627321008631
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A role for SMARCB1 in synovial sarcomagenesis reveals that SS18-SSX induces canonical BAF destruction

1
1. scibot 09 Nov 2021
  
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  DOI: 10.1158/2159-8290.CD-20-1219
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8567602/
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Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription

1
1. scibot 03 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.109943
  
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sciencedirect.com/science/article/pii/S2211124721014169
Jul 2021
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ATF3 modulates the macrophage immune response to Mycobacterium tuberculosis infection via reciprocal regulation of inflammatory genes and lipid body formation

1
1. scibot 31 Jul 2021
  
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  BRG1
  
  DOI: 10.1111/cmi.13142
  
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Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas

1
1. scibot 29 Jul 2021
  
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  RRID: 10861578
  
  DOI: 10.1016/j.celrep.2019.10.083
  
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Thyroid Hormone Receptor β Suppression of RUNX2 is Mediated by Brahma Related Gene 1 Dependent Chromatin Remodeling

1
1. scibot 29 Jul 2021
  
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  RRID:AB_10861578
  
  DOI: 10.1210/en.2018-00128
  
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Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition

1
1. scibot 21 May 2021
  
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  DOI: 10.1016/j.molcel.2021.04.015
  
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Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML

1
1. scibot 11 May 2021
  
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  RRID:AB_10861578
  
  DOI: 10.1016/j.molcel.2021.04.014
  
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A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin

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1. scibot 06 May 2021
  
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  RRID:AB_10861578
  
  DOI: 10.1016/j.immuni.2020.10.009
  
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Apr 2021
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A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms

2
1. scibot 24 Apr 2021
  
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  Rabbit Anti-SMARCA4 (BRG1) (EPNCIR111A) (WB)
  
  DOI: 10.1016/j.cell.2020.09.051
  
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2. scibot 24 Apr 2021
  
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  RRID:AB_10861578
  
  DOI: 10.1016/j.cell.2020.09.051
  
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Feb 2021
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A Genome-wide CRISPR Screen Reveals a Role for the Non-Canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function

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1. scibot 25 Feb 2021
  
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  DOI: 10.1016/j.immuni.2020.06.011
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7341821/
Jan 2021
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Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism

1
1. scibot 24 Jan 2021
  
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  RRID:AB_10861578
  
  DOI: 10.7554/eLife.59073
  
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Sep 2020
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Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma

1
1. scibot 06 Sep 2020
  
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  RRID:AB_10861578
  
  DOI: 10.1016/j.ccell.2020.04.002
  
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Jan 2020
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PRC1 Catalytic Activity Is Central to Polycomb System Function

1
1. scibot 13 Jan 2020
  
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  RRID:AB_10861578
  
  DOI: 10.1016/j.molcel.2019.12.001
  
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Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle

1
1. scibot 13 Jan 2020
  
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  RRID:AB_10861578
  
  DOI: 10.7554/eLife.50087
  
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Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling

1
1. scibot 13 Jan 2020
  
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  RRID:AB_10861578
  
  DOI: 10.1016/j.cell.2019.10.044
  
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:AB_10861578
  
  DOI: 10.1016/j.molcel.2019.03.024
  
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Nov 2018
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Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens

1
1. scibot 05 Nov 2018
  
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SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation

1
1. scibot 05 Nov 2018
  
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The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma

1
1. scibot 05 Nov 2018
  
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  RRID:AB_10861578
  
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Nov 2017
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The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin-Remodeling Complexes

1
1. scibot 08 Nov 2017
  
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  RRID:AB_10861578
  
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Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation

1
1. scibot 08 Nov 2017
  
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