52 Matching Annotations
  1. Jul 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer
    1
    1. scibot 25 Jul 2024
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      DOI: 10.1016/j.ccell.2024.06.012

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    sciencedirect.com/science/article/pii/S153561082400237X
  3. Jun 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CUX1 regulates human hematopoietic stem cell chromatin accessibility via the BAF complex
    1
    1. scibot 13 Jun 2024
      RRID:AB_10861578

      DOI: 10.1016/j.celrep.2024.114227

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    ncbi.nlm.nih.gov/pmc/articles/PMC11163479/
  5. www.sciencedirect.com www.sciencedirect.com
    Collaboration between distinct SWI/SNF chromatin remodeling complexes directs enhancer selection and activation of macrophage inflammatory genes
    1
    1. scibot 06 Jun 2024
      RRID:AB_10861578

      DOI: 10.1016/j.immuni.2024.05.008

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    sciencedirect.com/science/article/pii/S1074761324002620
  6. May 2024
  7. www.sciencedirect.com www.sciencedirect.com
    ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity
    1
    1. scibot 21 May 2024
      RRID:AB_10861578

      DOI: 10.1016/j.cell.2024.04.025

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    sciencedirect.com/science/article/pii/S0092867424004513
  8. www.sciencedirect.com www.sciencedirect.com
    Novel therapeutic strategies targeting bypass pathways and mitochondrial dysfunction to combat resistance to RET inhibitors in NSCLC
    1
    1. scibot 21 May 2024
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      DOI: 10.1016/j.bbadis.2024.167249

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    sciencedirect.com/science/article/pii/S0925443924002382
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular and pathological characterization of YAP1-expressing small cell lung cancer cell lines leads to reclassification as SMARCA4-deficient malignancies
    1
    1. scibot 03 May 2024
      RRID:AB_10861578

      DOI: 10.1158/1078-0432.CCR-23-2360

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    ncbi.nlm.nih.gov/pmc/articles/PMC11061608/
  10. www.jneurosci.org www.jneurosci.org
    SMARCA4 loss and mutated β-catenin induce proliferative lesions in the murine embryonic cerebellum
    1
    1. scibot 03 May 2024
      RRID:AB_10861578

      DOI: 10.1523/JNEUROSCI.1605-23.2024

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    jneurosci.org/content/44/15/e1605232024
  11. Apr 2024
  12. www.sciencedirect.com www.sciencedirect.com
    SP6 controls human cytotrophoblast fate decisions and trophoblast stem cell establishment by targeting MSX2 regulatory elements
    1
    1. scibot 09 Apr 2024
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      DOI: 10.1016/j.devcel.2024.03.025

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    sciencedirect.com/science/article/pii/S153458072400193X
  13. www.sciencedirect.com www.sciencedirect.com
    Enhancer switching in cell lineage priming is linked to eRNA, Brg1’s AT-hook, and SWI/SNF recruitment
    1
    1. scibot 09 Apr 2024
      RRID:AB_10861578

      DOI: 10.1016/j.molcel.2024.03.013

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    sciencedirect.com/science/article/pii/S1097276524002235
  14. Mar 2024
  15. www.sciencedirect.com www.sciencedirect.com
    SMARCA4 is a haploinsufficient B cell lymphoma tumor suppressor that fine-tunes centrocyte cell fate decisions
    2
    1. scibot 08 Mar 2024
      RRID:AB_10861578

      DOI: 10.1016/j.ccell.2024.02.011

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    2. scibot 08 Mar 2024
      RRID:AB_10861578

      DOI: 10.1016/j.ccell.2024.02.011

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    sciencedirect.com/science/article/pii/S1535610824000552
  16. www.sciencedirect.com www.sciencedirect.com
    The transcription factor NF-κB orchestrates nucleosome remodeling during the primary response to Toll-like receptor 4 signaling
    1
    1. scibot 05 Mar 2024
      RRID:AB_10861578

      DOI: 10.1016/j.immuni.2024.02.004

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    sciencedirect.com/science/article/pii/S1074761324000803
  17. Feb 2024
  18. 52.53.155.43 52.53.155.43
    d1-html.html
    1
    1. scibot 29 Feb 2024
      RRID:AB_10861578

      DOI: 10.1158/1078-0432.ccr-23-2360

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    52.53.155.43/9d9c84a50a37d03d2f105a9516b773f31c793012/d1-html.html
  19. 52.53.155.43 52.53.155.43
    JNEUROSCI.1605-23.2024.full-html.html
    3
    1. scibot 29 Feb 2024
      RRID:AB_10861578

      DOI: 10.1523/jneurosci.1605-23.2024

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    2. scibot 22 Feb 2024
      RRID:AB_10861578

      DOI: 10.1523/jneurosci.1605-23.2024

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    3. scibot 22 Feb 2024
      RRID:AB_10861578

      DOI: 10.1523/jneurosci.1605-23.2024

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    52.53.155.43/a2ff2f36d75df7a296c08e6dbda516d47b790121/JNEUROSCI.1605-23.2024.full (1)-html.html
  20. www.biorxiv.org www.biorxiv.org
    BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or Menin inhibitor
    1
    1. scibot 04 Feb 2024
      RRID:AB_10861578

      DOI: 10.1101/2023.09.28.560054

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    biorxiv.org/content/10.1101/2023.09.28.560054v1
  21. Nov 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Global identification of SWI/SNF targets reveals compensation by EP400
    1
    1. scibot 03 Nov 2023
      RRID:AB_10861578

      DOI: 10.1016/j.cell.2023.10.006

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    sciencedirect.com/science/article/pii/S0092867423010887
  23. link.springer.com link.springer.com
    MYC overexpression and SMARCA4 loss cooperate to drive medulloblastoma formation in mice
    1
    1. scibot 03 Nov 2023
      RRID:AB_10861578

      DOI: 10.1186/s40478-023-01654-2

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    link.springer.com/article/10.1186/s40478-023-01654-2
  24. Sep 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Myeloid BAF60a deficiency alters metabolic homeostasis and exacerbates atherosclerosis
    1
    1. scibot 30 Sep 2023
      RRID:AB_10861578

      DOI: 10.1016/j.celrep.2023.113171

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    sciencedirect.com/science/article/pii/S221112472301183X
  26. Jun 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Antiandrogen treatment induces stromal cell reprogramming to promote castration resistance in prostate cancer
    1
    1. scibot 23 Jun 2023
      RRID:AB_10861578

      DOI: 10.1016/j.ccell.2023.05.016

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    sciencedirect.com/science/article/pii/S1535610823001836
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation
    1
    1. scibot 07 Jun 2023
      AB_10861578

      DOI: 10.1016/j.immuni.2023.05.010

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    pmc.ncbi.nlm.nih.gov/articles/PMC10501989/
  29. Dec 2022
  30. aacrjournals.org aacrjournals.org
    BAF complex maintains glioma stem cells in pediatric H3K27M-glioma
    1
    1. scibot 03 Dec 2022
      RRID:AB_10861578

      DOI: 10.1158/2159-8290.CD-21-1491

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    aacrjournals.org/cancerdiscovery/article/12/12/2880/711164/BAF-Complex-Maintains-Glioma-Stem-Cells-in
  31. Oct 2022
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sensitive image-based chromatin binding assays using inducible ERα to rapidly characterize estrogenic chemicals and mixtures
    1
    1. scibot 14 Oct 2022
      RRID:AB_10861578

      DOI: 10.1016/j.isci.2022.105200

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    ncbi.nlm.nih.gov/pmc/articles/PMC9550643/
  33. www.nature.com www.nature.com
    A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo
    1
    1. scibot 11 Oct 2022
      RRID:AB_10861578

      DOI: 10.1038/s41467-022-33430-6

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    nature.com/articles/s41467-022-33430-6
  34. Aug 2022
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Smarca4 inactivation promotes lineage-specific transformation and early metastatic features in the lung
    1
    1. scibot 04 Aug 2022
      RRID:AB_10861578

      DOI: 10.1158/2159-8290.CD-21-0248

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    ncbi.nlm.nih.gov/pmc/articles/PMC8831463/
  36. Apr 2022
  37. www.sciencedirect.com www.sciencedirect.com
    Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma
    1
    1. scibot 07 Apr 2022
      RRID:AB_10861578

      DOI: 10.1016/j.celrep.2022.110637

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    sciencedirect.com/science/article/pii/S2211124722003898
  38. www.sciencedirect.com www.sciencedirect.com
    The FUS::DDIT3 fusion oncoprotein inhibits BAF complex targeting and activity in myxoid liposarcoma
    1
    1. scibot 07 Apr 2022
      RRID:AB_10861578

      DOI: 10.1016/j.molcel.2022.03.019

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    sciencedirect.com/science/article/pii/S109727652200257X
  39. Dec 2021
  40. www.sciencedirect.com www.sciencedirect.com
    IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer
    1
    1. scibot 22 Dec 2021
      RRID:AB_10861578

      DOI: 10.1016/j.celrep.2021.110138

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    sciencedirect.com/science/article/pii/S221112472101634X
  41. Nov 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Developmental defects in Huntington’s disease show that axonal growth and microtubule reorganization require NUMA1
    1
    1. scibot 18 Nov 2021
      RRID:AB_10861578

      DOI: 10.1016/j.neuron.2021.10.033

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    sciencedirect.com/science/article/pii/S0896627321008631
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A role for SMARCB1 in synovial sarcomagenesis reveals that SS18-SSX induces canonical BAF destruction
    1
    1. scibot 09 Nov 2021
      RRID:AB_10861578

      DOI: 10.1158/2159-8290.CD-20-1219

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    ncbi.nlm.nih.gov/pmc/articles/PMC8567602/
  44. www.sciencedirect.com www.sciencedirect.com
    Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription
    1
    1. scibot 03 Nov 2021
      RRID:AB_10861578

      DOI: 10.1016/j.celrep.2021.109943

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    sciencedirect.com/science/article/pii/S2211124721014169
  45. Jul 2021
  46. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ATF3 modulates the macrophage immune response to Mycobacterium tuberculosis infection via reciprocal regulation of inflammatory genes and lipid body formation
    1
    1. scibot 31 Jul 2021
      BRG1

      DOI: 10.1111/cmi.13142

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    onlinelibrary.wiley.com/doi/full/10.1111/cmi.13142
  47. www.sciencedirect.com www.sciencedirect.com
    Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas
    1
    1. scibot 29 Jul 2021
      RRID: 10861578

      DOI: 10.1016/j.celrep.2019.10.083

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    sciencedirect.com/science/article/pii/S2211124719314056
  48. academic.oup.com academic.oup.com
    Thyroid Hormone Receptor β Suppression of RUNX2 is Mediated by Brahma Related Gene 1 Dependent Chromatin Remodeling
    1
    1. scibot 29 Jul 2021
      RRID:AB_10861578

      DOI: 10.1210/en.2018-00128

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    academic.oup.com/endo/article/159/6/2484/4993923
  49. May 2021
  50. www.sciencedirect.com www.sciencedirect.com
    Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
    1
    1. scibot 21 May 2021
      RRID:AB_10861578

      DOI: 10.1016/j.molcel.2021.04.015

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    sciencedirect.com/science/article/pii/S1097276521003208
  51. www.sciencedirect.com www.sciencedirect.com
    Intrinsically disordered Meningioma-1 stabilizes the BAF complex to cause AML
    1
    1. scibot 11 May 2021
      RRID:AB_10861578

      DOI: 10.1016/j.molcel.2021.04.014

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    sciencedirect.com/science/article/pii/S1097276521003191
  52. www.sciencedirect.com www.sciencedirect.com
    A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin
    1
    1. scibot 06 May 2021
      RRID:AB_10861578

      DOI: 10.1016/j.immuni.2020.10.009

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    sciencedirect.com/science/article/pii/S1074761320304507
  53. Apr 2021
  54. www.sciencedirect.com www.sciencedirect.com
    A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms
    2
    1. scibot 24 Apr 2021
      Rabbit Anti-SMARCA4 (BRG1) (EPNCIR111A) (WB)

      DOI: 10.1016/j.cell.2020.09.051

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    2. scibot 24 Apr 2021
      RRID:AB_10861578

      DOI: 10.1016/j.cell.2020.09.051

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    sciencedirect.com/science/article/pii/S0092867420312484
  55. Feb 2021
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Genome-wide CRISPR Screen Reveals a Role for the Non-Canonical Nucleosome-Remodeling BAF Complex in Foxp3 Expression and Regulatory T Cell Function
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      DOI: 10.1016/j.immuni.2020.06.011

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  57. Jan 2021
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism
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  59. Sep 2020
  60. www.sciencedirect.com www.sciencedirect.com
    Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma
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      DOI: 10.1016/j.ccell.2020.04.002

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  61. Jan 2020
  62. www.sciencedirect.com www.sciencedirect.com
    PRC1 Catalytic Activity Is Central to Polycomb System Function
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.molcel.2019.12.001

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  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle
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      DOI: 10.7554/eLife.50087

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    Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling
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      DOI: 10.1016/j.cell.2019.10.044

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      DOI: 10.1016/j.molcel.2019.03.024

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  66. Nov 2018
  67. www.sciencedirect.com www.sciencedirect.com
    Interrogation of Mammalian Protein Complex Structure, Function, and Membership Using Genome-Scale Fitness Screens
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    SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation
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    The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma
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    1. scibot 05 Nov 2018
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  70. Nov 2017
  71. www.sciencedirect.com www.sciencedirect.com
    The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin-Remodeling Complexes
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    Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation
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