Hypothesis

21 Matching Annotations

Jan 2026
54.241.53.176 54.241.53.176

2026.01.19.700398v1.full-html.html

1
1. scibot 27 Jan 2026
  
  in Public
  
  RRID:AB_10861978
  
  DOI: 10.64898/2026.01.19.700398
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

Annotators

scibot

URL

54.241.53.176/920dac77fb602c31bea028e2a56d4a986d400748/2026.01.19.700398v1.full-html.html
Jun 2025
www.sciencedirect.com www.sciencedirect.com

Cohesin supercoils DNA during loop extrusion

1
1. scibot 14 Jun 2025
  
  in Public
  
  AB_10861978
  
  DOI: 10.1016/j.celrep.2025.115856
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124725006278
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TOP1 Mutations and Cross-Resistance to Antibody–Drug Conjugates in Patients with Metastatic Breast Cancer

1
1. scibot 20 May 2025
  
  in Public
  
  AB_10861978
  
  DOI: 10.1158/1078-0432.CCR-24-2771
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12079096/
www.sciencedirect.com www.sciencedirect.com

Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors

1
1. scibot 16 May 2025
  
  in Public
  
  AB_10861978
  
  DOI: 10.1016/j.cell.2025.04.012
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867425004143
Apr 2025
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

Allosteric modulation of protein kinase A in individuals affected by NLPD-PKA, a neurodegenerative disease in which the PRKAR1B L50R variant is expressed

1
1. scibot 19 Apr 2025
  
  in Public
  
  RRID:AB_10861978
  
  DOI: 10.1111/febs.70098
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

Annotators

scibot

URL

febs.onlinelibrary.wiley.com/doi/10.1111/febs.70098
Feb 2025
aacrjournals.org aacrjournals.org

PARP7 Inhibitors and AHR Agonists Act Synergistically Across a Wide-Range of Cancer Models

1
1. scibot 13 Feb 2025
  
  in Public
  
  RRID:AB_10861978
  
  DOI: 10.1158/1535-7163.MCT-24-0211
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

Annotators

scibot

URL

aacrjournals.org/mct/article/24/1/56/750662/PARP7-Inhibitors-and-AHR-Agonists-Act
Jan 2025
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 05 Jan 2025
  
  in Public
  
  RRID:AB_10861978
  
  DOI: 10.1158/1078-0432.ccr-24-2771
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

Annotators

scibot

URL

52.53.155.43/840490bae2d41c14c5baad0f632c2c699ffc05d9/PDF-html.html
Aug 2024
www.sciencedirect.com www.sciencedirect.com

RNA interacts with topoisomerase I to adjust DNA topology

1
1. scibot 23 Aug 2024
  
  in Public
  
  AB_10861978
  
  DOI: 10.1016/j.molcel.2024.07.032
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276524006300
Jul 2024
www.biorxiv.org www.biorxiv.org

Allosteric modulation of protein kinase A in individuals affected by NLPD-PKA, a neurodegenerative disease in which the RIβ-L50R variant is expressed

1
1. scibot 16 Jul 2024
  
  in Public
  
  RRID:AB_10861978
  
  DOI: 10.1101/2024.06.30.601371
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

Annotators

scibot

URL

biorxiv.org/content/10.1101/2024.06.30.601371v1
May 2024
www.sciencedirect.com www.sciencedirect.com

TDP1 mutation causing SCAN1 neurodegenerative syndrome hampers the repair of transcriptional DNA double-strand breaks

1
1. scibot 21 May 2024
  
  in Public
  
  RRID:AB_10861978
  
  DOI: 10.1016/j.celrep.2024.114214
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124724005424
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality

1
1. scibot 20 Dec 2023
  
  in Public
  
  RRID:RRID:AB_10861978
  
  DOI: 10.1158/0008-5472.CAN-22-2948
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10722143/
Jan 2023
www.sciencedirect.com www.sciencedirect.com

Centromeres as universal hotspots of DNA breakage, driving RAD51-mediated recombination during quiescence

1
1. scibot 26 Jan 2023
  
  in Public
  
  RRID:AB_10861978
  
  DOI: 10.1016/j.molcel.2023.01.004
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276523000047
Aug 2022
www.sciencedirect.com www.sciencedirect.com

TOP1 CAD-seq: A protocol to map catalytically engaged topoisomerase 1 in human cells

1
1. scibot 04 Aug 2022
  
  in Public
  
  RRID:AB_10861978
  
  DOI: 10.1016/j.xpro.2022.101581
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666166722004610
Dec 2021
www.cell.com www.cell.com

MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”

1
1. scibot 10 Dec 2021
  
  in Public
  
  RRID:AB_10861978
  
  DOI: 10.1016/j.molcel.2021.11.016
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

Annotators

scibot

URL

cell.com/molecular-cell/fulltext/S1097-2765(21)00996-5
Nov 2021
www.sciencedirect.com www.sciencedirect.com

Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1

1
1. scibot 12 Nov 2021
  
  in Public
  
  RRID:AB_10861978
  
  DOI: 10.1016/j.molcel.2021.10.015
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276521009072
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 09 Aug 2021
  
  in Public
  
  RRID:AB_10861978
  
  DOI: 10.1016/j.stem.2018.10.017
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590918304983
Apr 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation

1
1. scibot 14 Apr 2021
  
  in Public
  
  RRID:AB_10861978
  
  DOI: 10.1016/j.cell.2021.03.051
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

RRIDCUR:Validated

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8008343/
www.sciencedirect.com www.sciencedirect.com

Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing

1
1. scibot 14 Apr 2021
  
  in Public
  
  RRID:AB_10861978
  
  DOI: 10.1016/j.celrep.2021.108977
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRIDCUR:Validated RRID:AB_10861978
Visit annotations in context

Tags

RRID:AB_10861978

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721002916
Sep 2020
www.nature.com www.nature.com

N 6 -methyladenosine regulates the stability of RNA:DNA hybrids in human cells

1
1. scibot 03 Sep 2020
  
  in Public
  
  Top1
  
  DOI: 10.1038/s41588-019-0549-x
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_10861978
  
  Curator comments: Topoisomerase I antibody [EPR5375] Abcam Cat# ab109374
  
  What is this?
  
  RRID:AB_10861978 RRIDCUR:Missing
Visit annotations in context

Tags

RRID:AB_10861978

RRIDCUR:Missing

Annotators

scibot

URL

nature.com/articles/s41588-019-0549-x
Jan 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genetic interactions of G-quadruplexes in humans

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_10861978
  
  DOI: 10.7554/eLife.46793
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_10861978

RRIDCUR:Validated

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6615864/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The chromatin structuring protein HMGA2 influences human subtelomere stability and cancer chemosensitivity

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_10861978
  
  DOI: 10.1371/journal.pone.0215696
  
  Resource: (Abcam Cat# ab109374, RRID:AB_10861978)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_10861978
  
  What is this?
  
  RRID:AB_10861978 RRIDCUR:Validated
Visit annotations in context

Tags

RRID:AB_10861978

RRIDCUR:Validated

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6505889/