58 Matching Annotations
  1. Sep 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/Stat3 attenuation
    1
    1. scibot 18 Sep 2024
      AB_10891442

      DOI: 10.1038/s41523-024-00687-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11401886/
  3. Jul 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systems modeling of oncogenic G-protein and GPCR signaling reveals unexpected differences in downstream pathway activation
    1
    1. scibot 20 Jul 2024
      RRID:AB_10891442

      DOI: 10.1038/s41540-024-00400-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11252164/
  5. www.sciencedirect.com www.sciencedirect.com
    The extracellular matrix integrates mitochondrial homeostasis
    1
    1. scibot 19 Jul 2024
      AB_10891442

      DOI: 10.1016/j.cell.2024.05.057

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    sciencedirect.com/science/article/pii/S009286742400638X
  6. Jun 2024
  7. www.sciencedirect.com www.sciencedirect.com
    FAK regulates tension transmission to the nucleus and endothelial transcriptome independent of kinase activity
    1
    1. scibot 04 Jun 2024
      RRID:AB_10891442

      DOI: 10.1016/j.celrep.2024.114297

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    sciencedirect.com/science/article/pii/S2211124724006259
  8. May 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A proteomics approach to isolating neuropilin-dependent α5 integrin trafficking pathways: neuropilin 1 and 2 co-traffic α5 integrin through endosomal p120RasGAP to promote polarised fibronectin fibrillogenesis in endothelial cells
    1
    1. scibot 30 May 2024
      RRID:AB_10891442

      DOI: 10.1038/s42003-024-06320-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC11126613/
  10. www.sciencedirect.com www.sciencedirect.com
    Alarmin S100A8 imparts chemoresistance of esophageal cancer by reprogramming cancer-associated fibroblasts
    1
    1. scibot 23 May 2024
      RRID:AB_10891442

      DOI: 10.1016/j.xcrm.2024.101576

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    sciencedirect.com/science/article/pii/S2666379124002684
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repurposing homoharringtonine for thyroid cancer treatment through TIMP1/FAK/PI3K/AKT signaling pathway
    1
    1. scibot 23 May 2024
      RRID:AB_10891442

      DOI: 10.1016/j.isci.2024.109829

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    ncbi.nlm.nih.gov/pmc/articles/PMC11103377/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ATG9B regulates bacterial internalization via actin rearrangement
    1
    1. scibot 05 May 2024
      RRID:AB_10891442

      DOI: 10.1016/j.isci.2024.109623

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    ncbi.nlm.nih.gov/pmc/articles/PMC11066431/
  13. Apr 2024
  14. aacrjournals.org aacrjournals.org
    Sarcoma cells secrete hypoxia-modified collagen VI to weaken the lung endothelial barrier and promote metastasis
    1
    1. scibot 19 Apr 2024
      RRID:AB_10891442

      DOI: 10.1158/0008-5472.CAN-23-0910

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    aacrjournals.org/cancerres/article/84/7/977/742043/Sarcoma-Cells-Secrete-Hypoxia-Modified-Collagen-VI
  15. Mar 2024
  16. www.sciencedirect.com www.sciencedirect.com
    IQGAP1 and NWASP promote human cancer cell dissemination and metastasis by regulating β1-integrin via FAK and MRTF/SRF
    2
    1. scibot 28 Mar 2024
      RRID:AB_10891442

      DOI: 10.1016/j.celrep.2024.113989

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    2. scibot 28 Mar 2024
      RRID:AB_10891442

      DOI: 10.1016/j.celrep.2024.113989

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    sciencedirect.com/science/article/pii/S2211124724003176
  17. Jan 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Mechanosensitive hormone signaling promotes mammary progenitor expansion and breast cancer risk
    1
    1. scibot 11 Jan 2024
      RRID:AB_10891442

      DOI: 10.1016/j.stem.2023.12.002

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    sciencedirect.com/science/article/pii/S1934590923004320
  19. Dec 2023
  20. www.biorxiv.org www.biorxiv.org
    Together, Neuropilin 1 and Neuropilin 2 direct α5 integrin trafficking through GTPase-activating-protein p120RasGAP in endothelial cells to promote fibronectin fibrillogenesis
    1
    1. scibot 02 Dec 2023
      RRID:AB_10891442

      DOI: 10.1101/2023.11.28.568967

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    biorxiv.org/content/10.1101/2023.11.28.568967v1
  21. Nov 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Brain metastasis-associated fibroblasts secrete fucosylated PVR/CD155 that induces breast cancer invasion
    1
    1. scibot 28 Nov 2023
      RRID:AB_10891442

      DOI: 10.1016/j.celrep.2023.113463

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    sciencedirect.com/science/article/pii/S2211124723014754
  23. Oct 2023
  24. www.sciencedirect.com www.sciencedirect.com
    High-throughput chemogenetic drug screening reveals PKC-RhoA/PKN as a targetable signaling vulnerability in GNAQ-driven uveal melanoma
    1
    1. scibot 28 Oct 2023
      RRID:AB_10891442

      DOI: 10.1016/j.xcrm.2023.101244

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    sciencedirect.com/science/article/pii/S2666379123004214
  25. www.sciencedirect.com www.sciencedirect.com
    Collagen 1-mediated CXCL1 secretion in tumor cells activates fibroblasts to promote radioresistance of esophageal cancer
    1
    1. scibot 27 Oct 2023
      RRID:AB_10891442

      DOI: 10.1016/j.celrep.2023.113270

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    sciencedirect.com/science/article/pii/S2211124723012822
  26. aiche.onlinelibrary.wiley.com aiche.onlinelibrary.wiley.com
    Mechanochemical coupling of MGF mediates periodontal regeneration
    1
    1. scibot 09 Oct 2023
      RRID:AB_10891442

      DOI: 10.1002/btm2.10603

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    aiche.onlinelibrary.wiley.com/doi/10.1002/btm2.10603
  27. Aug 2023
  28. www.sciencedirect.com www.sciencedirect.com
    CdGAP is a talin-binding protein and a target of TGF-β signaling that promotes HER2-positive breast cancer growth and metastasis
    1
    1. scibot 10 Aug 2023
      RRID:AB_10891442

      DOI: 10.1016/j.celrep.2023.112936

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    sciencedirect.com/science/article/pii/S2211124723009476
  29. Jul 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression
    1
    1. scibot 06 Jul 2023
      RRID:AB_10891442

      DOI: 10.1158/1535-7163.MCT-22-0147

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    ncbi.nlm.nih.gov/pmc/articles/PMC9812929/
  31. Jun 2023
  32. 52.53.155.43 52.53.155.43
    Macrophage-derived cathepsin S remodels the extracellular matrix to promote liver fibrogenesis
    1
    1. scibot 16 Jun 2023
      RRID:AB_10891442

      DOI: 10.1053/j.gastro.2023.05.039

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    52.53.155.43/6547da8aa0b8d7e491fdd14880a12803f28db0ef/1-s2.0-S0016508523008120-main-html.html
  33. Apr 2023
  34. aacrjournals.org aacrjournals.org
    CD142 Identifies Neoplastic Desmoid Tumor Cells, Uncovering Interactions Between Neoplastic and Stromal Cells That Drive Proliferation
    1
    1. scibot 28 Apr 2023
      RRID:AB_10891442

      DOI: 10.1158/2767-9764.CRC-22-0403

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    aacrjournals.org/cancerrescommun/article/3/4/697/726086/CD142-Identifies-Neoplastic-Desmoid-Tumor-Cells
  35. Mar 2023
  36. www.sciencedirect.com www.sciencedirect.com
    FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression
    1
    1. scibot 02 Mar 2023
      RRID:AB_10891442

      DOI: 10.1016/j.celrep.2023.112188

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    sciencedirect.com/science/article/pii/S2211124723001997
  37. Feb 2023
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells
    1
    1. scibot 17 Feb 2023
      RRID:AB_10891442

      DOI: 10.1126/scisignal.abj5879

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    ncbi.nlm.nih.gov/pmc/articles/PMC9528501/
  39. www.sciencedirect.com www.sciencedirect.com
    GPR143 controls ESCRT-dependent exosome biogenesis and promotes cancer metastasis
    1
    1. scibot 17 Feb 2023
      RRID:AB_10891442

      DOI: 10.1016/j.devcel.2023.01.006

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    sciencedirect.com/science/article/pii/S1534580723000370
  40. www.embopress.org www.embopress.org
    The mechanosensitive TRPV2 calcium channel promotes human melanoma invasiveness and metastatic potential
    1
    1. scibot 09 Feb 2023
      RRID:AB_10891442

      DOI: 10.15252/embr.202255069

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    embopress.org/doi/10.15252/embr.202255069
  41. Jan 2023
  42. www.sciencedirect.com www.sciencedirect.com
    GSNOR deficiency promotes tumor growth via FAK1 S-nitrosylation
    1
    1. scibot 19 Jan 2023
      RRID:AB_10891442

      DOI: 10.1016/j.celrep.2023.111997

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    sciencedirect.com/science/article/pii/S2211124723000086
  43. www.sciencedirect.com www.sciencedirect.com
    A Cdh3-β-catenin-laminin signaling axis in a subset of breast tumor leader cells control leader cell polarization and directional collective migration
    1
    1. scibot 11 Jan 2023
      RRID:AB_10891442

      DOI: 10.1016/j.devcel.2022.12.005

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    sciencedirect.com/science/article/pii/S1534580722008498
  44. Nov 2022
  45. academic.oup.com academic.oup.com
    CRABP2 is associated with thyroid cancer recurrence and promotes invasion via the integrin/FAK/AKT pathway
    1
    1. scibot 18 Nov 2022
      RRID:AB_10891442

      DOI: 10.1210/endocr/bqac171

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    academic.oup.com/endo/article-abstract/163/12/bqac171/6761323
  46. link.springer.com link.springer.com
    Dual anti-angiogenic and anti-metastatic activity of myriocin synergistically enhances the anti-tumor activity of cisplatin
    1
    1. scibot 05 Nov 2022
      RRID:AB_10891442

      DOI: 10.1007/s13402-022-00737-x

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    link.springer.com/article/10.1007/s13402-022-00737-x
  47. Oct 2022
  48. www.nature.com www.nature.com
    The Cancermuts software package for the prioritization of missense cancer variants: a case study of AMBRA1 in melanoma
    1
    1. scibot 18 Oct 2022
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      DOI: 10.1038/s41419-022-05318-2

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    nature.com/articles/s41419-022-05318-2
  49. www.sciencedirect.com www.sciencedirect.com
    Competition for endothelial cell polarity drives vascular morphogenesis in the mouse retina
    2
    1. scibot 11 Oct 2022
      RRID:AB_10891442

      DOI: 10.1016/j.devcel.2022.09.002

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      DOI: 10.1016/j.devcel.2022.09.002

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    sciencedirect.com/science/article/pii/S1534580722006323
  50. Jun 2022
  51. www.sciencedirect.com www.sciencedirect.com
    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
    1
    1. scibot 25 Jun 2022
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      DOI: 10.1016/j.molcel.2022.06.005

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    sciencedirect.com/science/article/pii/S109727652200541X
  52. Apr 2022
  53. link.springer.com link.springer.com
    Protrudin regulates FAK activation, endothelial cell migration and angiogenesis
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    1. scibot 05 Apr 2022
      RRID:AB_10891442

      DOI: 10.1007/s00018-022-04251-z

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    link.springer.com/article/10.1007/s00018-022-04251-z
  54. Feb 2022
  55. link.springer.com link.springer.com
    Angiopoietin-2-induced lymphatic endothelial cell migration drives lymphangiogenesis via the β1 integrin-RhoA-formin axis
    1
    1. scibot 02 Feb 2022
      RRID:AB_10891442

      DOI: 10.1007/s10456-022-09831-y

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    link.springer.com/article/10.1007/s10456-022-09831-y
  56. Jan 2022
  57. www.sciencedirect.com www.sciencedirect.com
    GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis
    1
    1. scibot 13 Jan 2022
      RRID:AB_10891442

      DOI: 10.1016/j.cell.2021.12.024

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    sciencedirect.com/science/article/pii/S0092867421014872
  58. Nov 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Deciphering cell signaling networks with massively multiplexed biosensor barcoding
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    1. scibot 30 Nov 2021
      RRID:AB_10891442

      DOI: 10.1016/j.cell.2021.11.005

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    sciencedirect.com/science/article/pii/S0092867421013209
  60. Sep 2021
  61. www.sciencedirect.com www.sciencedirect.com
    Senescent immune cells release grancalcin to promote skeletal aging
    1
    1. scibot 14 Sep 2021
      RRID:AB_10891442

      DOI: 10.1016/j.cmet.2021.08.009

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    sciencedirect.com/science/article/pii/S1550413121003727
  62. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Retraction fibers produced by fibronectin-integrin α5β1 interaction promote motility of brain tumor cells
    1
    1. scibot 09 Sep 2021
      8556

      DOI: 10.1096/fj.202100452RR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202100452RR
  63. Jul 2021
  64. www.sciencedirect.com www.sciencedirect.com
    Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling
    1
    1. scibot 28 Jul 2021
      RRID:AB_10891442

      DOI: 10.1016/j.ccell.2018.11.016

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    sciencedirect.com/science/article/pii/S1535610818305373
  65. May 2021
  66. www.sciencedirect.com www.sciencedirect.com
    Induction of cyclophilin A by influenza A virus infection facilitates group A Streptococcus coinfection
    1
    1. scibot 19 May 2021
      RRID:AB_10891442

      DOI: 10.1016/j.celrep.2021.109159

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    sciencedirect.com/science/article/pii/S2211124721005015
  67. www.nature.com www.nature.com
    Loss of Ambra1 promotes melanoma growth and invasion
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    1. scibot 12 May 2021
      RRID:AB_10891442

      DOI: 10.1038/s41467-021-22772-2

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    nature.com/articles/s41467-021-22772-2
  68. Dec 2020
  69. www.sciencedirect.com www.sciencedirect.com
    Gain-of-function hot spot mutant p53R248Q regulation of integrin/FAK/ERK signaling in esophageal squamous cell carcinoma
    1
    1. scibot 15 Dec 2020
      phospho-FAK

      DOI: 10.1016/j.tranon.2020.100982

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    sciencedirect.com/science/article/pii/S1936523320304745
  70. Oct 2020
  71. www.cell.com www.cell.com
    Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex
    1
    1. scibot 16 Oct 2020
      RRID:AB_10891442

      DOI: 10.1016/j.devcel.2020.05.031

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    cell.com/developmental-cell/abstract/S1534-5807(20)30420-2
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis
    1
    1. scibot 13 Oct 2020
      RRID:AB_10891442

      DOI: 10.7554/eLife.59442

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    ncbi.nlm.nih.gov/pmc/articles/PMC7541088/
  73. Sep 2020
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Arginine methylation of SHANK2 by PRMT7 promotes human breast cancer metastasis through activating endosomal FAK signalling
    1
    1. scibot 23 Sep 2020
      RRID:AB_10891442

      DOI: 10.7554/eLife.57617

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    ncbi.nlm.nih.gov/pmc/articles/PMC7494359/
  75. link.springer.com link.springer.com
    Targeting the Tie2–α v β 3 integrin axis with bi-specific reagents for the inhibition of angiogenesis
    1
    1. scibot 14 Sep 2020
      RRID:AB_10891442

      DOI: 10.1186/s12915-018-0557-9

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    link.springer.com/article/10.1186/s12915-018-0557-9
  76. www.sciencedirect.com www.sciencedirect.com
    Secreted Pyruvate Kinase M2 Promotes Lung Cancer Metastasis through Activating the Integrin Beta1/FAK Signaling Pathway
    1
    1. scibot 08 Sep 2020
      RRID:AB_10891442

      DOI: 10.1016/j.celrep.2020.01.037

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    sciencedirect.com/science/article/pii/S2211124720300528
  77. www.sciencedirect.com www.sciencedirect.com
    OVA66 promotes tumour angiogenesis and progression through enhancing autocrine VEGF-VEGFR2 signalling
    1
    1. scibot 04 Sep 2020
      RRID: AB_10891442

      DOI: 10.1016/j.ebiom.2019.02.051

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    sciencedirect.com/science/article/pii/S2352396419301306
  78. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel role for CRK adaptor proteins as essential components of SRC/FAK signaling for epithelial‐mesenchymal transition and colorectal cancer aggressiveness
    1
    1. scibot 04 Sep 2020
      Y397 phospho‐FAK

      DOI: 10.1002/ijc.32955

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    onlinelibrary.wiley.com/doi/10.1002/ijc.32955
  79. Jan 2020
  80. www.sciencedirect.com www.sciencedirect.com
    Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets
    1
    1. scibot 13 Jan 2020
      RRID:AB_10891442

      DOI: 10.1016/j.chembiol.2019.06.003

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    sciencedirect.com/science/article/pii/S2451945619302041
  81. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_10891442

      DOI: 10.1016/j.ccell.2019.01.009

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    sciencedirect.com/science/article/pii/S1535610819300431
  82. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 12 Jan 2020
      RRID:AB_10891442

      DOI: 10.1016/j.devcel.2019.04.007

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    sciencedirect.com/science/article/pii/S1534580719302771
  83. Nov 2018
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      RRID:AB_10891442

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    ncbi.nlm.nih.gov/pmc/articles/PMC6097439/
  85. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    Untitled document
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      RRID:AB_10891442

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    bmcbiol.biomedcentral.com/articles/10.1186/s12915-018-0557-9
  86. academic.oup.com academic.oup.com
    Insulinlike Growth Factor–Binding Protein-1 Improves Vascular Endothelial Repair in Male Mice in the Setting of Insulin Resistance
    1
    1. scibot 05 Nov 2018
      AB_10891442

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    academic.oup.com/endo/article/159/2/696/4657266
  87. www.jneurosci.org www.jneurosci.org
    Untitled document
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    1. scibot 05 Nov 2018
      RRID:AB_10891442

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    jneurosci.org/content/37/46/11271
  88. Nov 2017
  89. www.sciencedirect.com www.sciencedirect.com
    Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma
    1
    1. scibot 08 Nov 2017
      AB_10891442

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S1934590917301376