95 Matching Annotations
  1. Oct 2024
  2. link.springer.com link.springer.com
    Multiplexed chromatin immunoprecipitation sequencing for quantitative study of histone modifications and chromatin factors
    1
    1. scibot 08 Oct 2024
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      DOI: 10.1038/s41596-024-01058-z

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    link.springer.com/article/10.1038/s41596-024-01058-z
  3. Aug 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Protocol for establishing inducible CRISPRd system for blocking transcription factor-binding sites in human pluripotent stem cells
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.xpro.2024.103233

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    sciencedirect.com/science/article/pii/S2666166724003988
  5. May 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Enhanced ApcMin/+ adenoma formation after epithelial CUL4B deletion by recruitment of myeloid-derived suppressor cells
    1
    1. scibot 21 May 2024
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      DOI: 10.1016/j.neo.2024.101005

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    sciencedirect.com/science/article/pii/S1476558624000472
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    Improved detection of DNA replication fork-associated proteins
    1
    1. scibot 07 May 2024
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      DOI: 10.1016/j.celrep.2024.114178

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    sciencedirect.com/science/article/pii/S2211124724005060
  8. Apr 2024
  9. rupress.org rupress.org
    DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response
    1
    1. scibot 25 Apr 2024
      RRID:AB_10891618

      DOI: 10.1083/jcb.202303141

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    rupress.org/jcb/article/223/5/e202303141/276604/DUX4-induced-HSATII-transcription-causes-KDM2A-B
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    H2AK119ub1 differentially fine-tunes gene expression by modulating canonical PRC1- and H1-dependent chromatin compaction
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.molcel.2024.02.017

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    sciencedirect.com/science/article/pii/S1097276524001369
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CBX7C•PHC2 interaction facilitates PRC1 assembly and modulates its phase separation properties
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.isci.2024.109548

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    ncbi.nlm.nih.gov/pmc/articles/PMC11004992/
  12. Jan 2024
  13. www.sciencedirect.com www.sciencedirect.com
    PCGF6 controls murine Tuft cell differentiation via H3K9me2 modification independently of Polycomb repression
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    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.devcel.2023.12.015

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    sciencedirect.com/science/article/pii/S1534580723006962
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    Pioneer and PRDM transcription factors coordinate bivalent epigenetic states to safeguard cell fate
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.molcel.2023.12.007

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    sciencedirect.com/science/article/pii/S1097276523010262
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    XIST directly regulates X-linked and autosomal genes in naive human pluripotent cells
    1
    1. scibot 05 Jan 2024
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      DOI: 10.1016/j.cell.2023.11.033

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    sciencedirect.com/science/article/pii/S0092867423013193
  16. Dec 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromosome-specific maturation of the epigenome in the Drosophila male germline
    1
    1. scibot 02 Dec 2023
      RRID:AB_10891618

      DOI: 10.7554/eLife.89373

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    ncbi.nlm.nih.gov/pmc/articles/PMC10688970/
  18. Oct 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Three-dimensional genome architecture coordinates key regulators of lineage specification in mammary epithelial cells
    1
    1. scibot 27 Oct 2023
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      DOI: 10.1016/j.xgen.2023.100424

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    sciencedirect.com/science/article/pii/S2666979X23002501
  20. Sep 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Discordant interactions between YAP1 and polycomb group protein SCML2 determine cell fate
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.isci.2023.107964

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    sciencedirect.com/science/article/pii/S2589004223020412
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    Multi-omics comparison of malignant and normal uveal melanocytes reveals molecular features of uveal melanoma
    1
    1. scibot 16 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113132

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    sciencedirect.com/science/article/pii/S2211124723011440
  23. Jul 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Proximity-dependent recruitment of Polycomb repressive complexes by the lncRNA Airn
    1
    1. scibot 13 Jul 2023
      RRID:AB_10891618

      DOI: 10.1016/j.celrep.2023.112803

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    sciencedirect.com/science/article/pii/S2211124723008148
  25. Jun 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Early chromosome condensation by XIST builds A-repeat RNA density that facilitates gene silencing
    1
    1. scibot 29 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112686

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    sciencedirect.com/science/article/pii/S2211124723006976
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis
    1
    1. scibot 24 Jun 2023
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      DOI: 10.7554/eLife.83004

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    ncbi.nlm.nih.gov/pmc/articles/PMC10287155/
  28. 52.53.155.43 52.53.155.43
    Disease Tolerance Acquired Through Repeated Plasmodium Infection Involves Epigenetic Reprogramming of Innate Immune Cells
    1
    1. scibot 01 Jun 2023
      RRID:AB_10891618

      DOI: 10.1101/2023.04.19.537546

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    52.53.155.43/5bbec45c5ee0125efd6c9cfa2bbd025875f2b7a1/2023.04.19.537546v1.full-html.html
  29. May 2023
  30. www.biorxiv.org www.biorxiv.org
    Epigenetic reprogramming of imprinting at meiosis
    1
    1. scibot 25 May 2023
      RRID:AB_10891618

      DOI: 10.1101/2023.05.17.541143

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    biorxiv.org/content/10.1101/2023.05.17.541143v1
  31. www.sciencedirect.com www.sciencedirect.com
    Depletion of CUL4B in macrophages ameliorates diabetic kidney disease via miR-194-5p/ITGA9 axis
    1
    1. scibot 24 May 2023
      RRID:AB_10891618

      DOI: 10.1016/j.celrep.2023.112550

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    sciencedirect.com/science/article/pii/S2211124723005612
  32. 52.53.155.43 52.53.155.43
    mcr-22-1012-html.html
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    1. scibot 11 May 2023
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      DOI: 10.1158/1541-7786.MCR-22-1012

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    52.53.155.43/f1c718492b613520e7ca38a872e493e24e232a60/mcr-22-1012-html.html
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BAP1 loss is associated with higher ASS1 expression in epithelioid mesothelioma: implications for therapeutic stratification.
    1
    1. scibot 04 May 2023
      RRID:AB_10891618

      DOI: 10.1158/1541-7786.MCR-22-0635

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    ncbi.nlm.nih.gov/pmc/articles/PMC10150242/
  34. Apr 2023
  35. www.sciencedirect.com www.sciencedirect.com
    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
    1
    1. scibot 29 Apr 2023
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      DOI: 10.1016/j.molcel.2023.04.005

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    sciencedirect.com/science/article/pii/S1097276523002496
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    PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1
    1
    1. scibot 08 Apr 2023
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      DOI: 10.1016/j.molcel.2023.03.018

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    sciencedirect.com/science/article/pii/S1097276523002083
  37. Feb 2023
  38. www.sciencedirect.com www.sciencedirect.com
    Recycling of modified H2A-H2B provides short-term memory of chromatin states
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    1. scibot 09 Feb 2023
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      DOI: 10.1016/j.cell.2023.01.007

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    sciencedirect.com/science/article/pii/S0092867423000077
  39. Jan 2023
  40. www.nature.com www.nature.com
    Targeting Menin disrupts the KMT2A/B and polycomb balance to paradoxically activate bivalent genes
    1
    1. scibot 19 Jan 2023
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      DOI: 10.1038/s41556-022-01056-x

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    nature.com/articles/s41556-022-01056-x
  41. Nov 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Essential role of MESP1-RING1A complex in cardiac differentiation
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    1. scibot 22 Nov 2022
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      DOI: 10.1016/j.devcel.2022.10.009

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    sciencedirect.com/science/article/pii/S1534580722007614
  43. Oct 2022
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes
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    1. scibot 12 Oct 2022
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      DOI: 10.1158/2643-3230.BCD-21-0115

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    ncbi.nlm.nih.gov/pmc/articles/PMC9414116/
  45. Aug 2022
  46. www.sciencedirect.com www.sciencedirect.com
    A small RNA-guided PRC2 complex eliminates DNA as an extreme form of transposon silencing
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    1. scibot 26 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111263

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    sciencedirect.com/science/article/pii/S2211124722010816
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    Chromosome silencing in vitro reveals trisomy 21 causes cell-autonomous deficits in angiogenesis and early dysregulation in Notch signaling
    1
    1. scibot 10 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111174

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    sciencedirect.com/science/article/pii/S2211124722009871
  48. Jun 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas
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    1. scibot 18 Jun 2022
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      DOI: 10.1016/j.molcel.2022.05.023

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    sciencedirect.com/science/article/pii/S1097276522004907
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    Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
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      DOI: 10.1016/j.isci.2022.104519

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    sciencedirect.com/science/article/pii/S2589004222007908
  51. May 2022
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Binary outcomes of enhancer activity underlie stable random monoallelic expression
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    1. scibot 28 May 2022
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      DOI: 10.7554/eLife.74204

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    ncbi.nlm.nih.gov/pmc/articles/PMC9135403/
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    XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation
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      DOI: 10.1016/j.cell.2022.04.034

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    sciencedirect.com/science/article/pii/S0092867422005323
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    Nde1 is required for heterochromatin compaction and stability in neocortical neurons
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      DOI: 10.1016/j.isci.2022.104354

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    sciencedirect.com/science/article/pii/S2589004222006253
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    Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1
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    1. scibot 19 May 2022
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      DOI: 10.1016/j.celrep.2022.110830

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    sciencedirect.com/science/article/pii/S2211124722006015
  56. Apr 2022
  57. www.sciencedirect.com www.sciencedirect.com
    L3MBTL2-mediated CGA transcriptional suppression promotes pancreatic cancer progression through modulating autophagy
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    1. scibot 26 Apr 2022
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      DOI: 10.1016/j.isci.2022.104249

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    sciencedirect.com/science/article/pii/S2589004222005193
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    Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis
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    1. scibot 06 Apr 2022
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      DOI: 10.1016/j.celrep.2022.110587

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    sciencedirect.com/science/article/pii/S221112472200331X
  59. Mar 2022
  60. www.sciencedirect.com www.sciencedirect.com
    BMI-1 regulates DNA end resection and homologous recombination repair
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    1. scibot 23 Mar 2022
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  61. Feb 2022
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    Bivalent-histone-marked immediate-early gene regulation is vital for VEGF-responsive angiogenesis
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  63. Jan 2022
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Establishment of developmental gene silencing by ordered polycomb complex recruitment in early zebrafish embryos
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  65. Dec 2021
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    Distal and proximal cis-regulatory elements sense X chromosome dosage and developmental state at the Xist locus
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  67. Nov 2021
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    Inherent genomic properties underlie the epigenomic heterogeneity of human induced pluripotent stem cells
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  70. Oct 2021
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  75. Aug 2021
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    The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes
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  82. Jul 2021
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    SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States
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  87. Jun 2021
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    BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation
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    H3K27 demethylases are dispensable for activation of Polycomb-regulated injury response genes in peripheral nerve.
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  90. May 2021
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    BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse
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    The USP7-TRIM27 axis mediates non-canonical PRC1.1 function and is a druggable target in leukemia
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  94. Apr 2021
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  96. Feb 2021
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  98. Oct 2020
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    Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG
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  100. Sep 2020
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  103. Jan 2020
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    lncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA
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    PRC1 Catalytic Activity Is Central to Polycomb System Function
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    Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression
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    Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7
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    Polycomb Group Proteins Regulate Chromatin Architecture in Mouse Oocytes and Early Embryos
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    Epigenetic silencing of a multifunctional plant stress regulator
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    sciencedirect.com/science/article/pii/S1097276518310700
  114. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 13 Jan 2020
      RRID:AB_10891618

      DOI: 10.1016/j.molcel.2019.03.024

      Resource: (Cell Signaling Technology Cat# 8240, RRID:AB_10891618)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S109727651930228X
  115. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_10891618

      DOI: 10.1016/j.molcel.2019.04.002

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    sciencedirect.com/science/article/pii/S1097276519302722
  116. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 13 Jan 2020
      RRID:AB_10891618

      DOI: 10.1016/j.stem.2019.04.017

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    sciencedirect.com/science/article/pii/S1934590919301663
  117. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_10891618

      DOI: 10.1016/j.molcel.2019.03.018

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    sciencedirect.com/science/article/pii/S1097276519302229
  118. www.sciencedirect.com www.sciencedirect.com
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    1. scibot 12 Jan 2020
      RRID:AB_10891618

      DOI: 10.1016/j.devcel.2019.03.011

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    sciencedirect.com/science/article/pii/S1534580719301881
  119. Nov 2018
  120. www.sciencedirect.com www.sciencedirect.com
    Genetic Modulation of RNA Splicing with a CRISPR-Guided Cytidine Deaminase
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      Curator: @Jmenke

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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes
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      Curator: @evieth

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  122. www.sciencedirect.com www.sciencedirect.com
    A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities
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    sciencedirect.com/science/article/pii/S1097276518301862
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    sciencedirect.com/science/article/pii/S2405471217304350
  124. www.sciencedirect.com www.sciencedirect.com
    A Non-canonical BCOR-PRC1.1 Complex Represses Differentiation Programs in Human ESCs
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      RRID:AB_10891618

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    sciencedirect.com/science/article/pii/S1934590917305027
  125. Nov 2017
  126. www.sciencedirect.com www.sciencedirect.com
    ASF1a Promotes Non-homologous End Joining Repair by Facilitating Phosphorylation of MDC1 by ATM at Double-Strand Breaks
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    1. scibot 08 Nov 2017
      RRID:AB_10891618

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276517306184
  127. www.sciencedirect.com www.sciencedirect.com
    Polycomb Repressive Complex 1 Generates Discrete Compacted Domains that Change during Differentiation
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    1. scibot 08 Nov 2017
      RRID:AB_10891618

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    sciencedirect.com/science/article/pii/S1097276517300357
  128. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin Modification by the E3 Ligase/ADP-Ribosyltransferase Dtx3L/Parp9
    1
    1. scibot 08 Nov 2017
      Ub-H2ACell Signaling Technology8240

      Curator: @Jmenke

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      RRID:AB_10891618 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1097276517303131
  129. elifesciences.org elifesciences.org
    PCGF6-PRC1 suppresses premature differentiation of mouse embryonic stem cells by regulating germ cell-related genes
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    1. scibot 08 Nov 2017
      AB_10891618

      Curator: @kaitlinsung

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    elifesciences.org/content/6/e21064
  130. www.sciencedirect.com www.sciencedirect.com
    Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways
    1
    1. scibot 08 Nov 2017
      AB_10891618

      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S1097276517300564
  131. www.sciencedirect.com www.sciencedirect.com
    RNA Helicase DDX5 Inhibits Reprogramming to Pluripotency by miRNA-Based Repression of RYBP and its PRC1-Dependent and -Independent Functions
    1
    1. scibot 08 Nov 2017
      AB_10891618

      Curator: @gabimpine

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      (Cell Signaling Technology Cat# 8240, RRID:AB_10891618)

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      RRID:AB_10891618 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1934590916304581