Hypothesis

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Hypoxia promotes airway differentiation in the human lung epithelium

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1. scibot 11 Oct 2025
  
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  DOI: 10.1016/j.stem.2025.09.007
  
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sciencedirect.com/science/article/pii/S1934590925003388
Mar 2025
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The pro-inflammatory cytokine IL6 suppresses mitochondrial function via the gp130-JAK1/STAT1/3-HIF1α/ERRα axis

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1. scibot 11 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115403
  
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sciencedirect.com/science/article/pii/S2211124725001743
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy

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1. scibot 04 Mar 2025
  
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  DOI: 10.1016/j.cell.2025.01.046
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11988688/
Jan 2025
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Conserved patterns of transcriptional dysregulation, heterogeneity, and cell states in clear cell kidney cancer

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1. scibot 14 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115169
  
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sciencedirect.com/science/article/pii/S2211124724015201
Jan 2024
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Kinome-wide siRNA screen identifies a DCLK2-TBK1 oncogenic signaling axis in clear cell renal cell carcinoma

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1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.molcel.2023.12.010
  
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sciencedirect.com/science/article/pii/S1097276523010298
Dec 2023
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MORG1 limits mTORC1 signaling by inhibiting Rag GTPases

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1. scibot 16 Dec 2023
  
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  DOI: 10.1016/j.molcel.2023.11.023
  
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sciencedirect.com/science/article/pii/S1097276523009681
May 2023
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KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells

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1. scibot 05 May 2023
  
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  DOI: 10.1016/j.celrep.2022.111077
  
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sciencedirect.com/science/article/pii/S2211124722008750
Nov 2022
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Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature

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1. scibot 16 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111652
  
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sciencedirect.com/science/article/pii/S2211124722015236
Oct 2022
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Circadian lncRNA ADIRF-AS1 binds PBAF and regulates renal clear cell tumorigenesis

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1. scibot 20 Oct 2022
  
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  DOI: 10.1016/j.celrep.2022.111514
  
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sciencedirect.com/science/article/pii/S221112472201364X
Jun 2022
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An oncogenic JMJD6-DGAT1 axis tunes the epigenetic regulation of lipid droplet formation in clear cell renal cell carcinoma

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1. scibot 29 Jun 2022
  
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  DOI: 10.1016/j.molcel.2022.06.003
  
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sciencedirect.com/science/article/pii/S1097276522005391
Sep 2021
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A strategy to assess the cellular activity of E3 ligase components against neo-substrates using electrophilic probes

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1. scibot 09 Sep 2021
  
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  RRID:AB_10898028
  
  DOI: 10.1016/j.chembiol.2021.08.007
  
  Resource: (Cell Signaling Technology Cat# 7096, RRID:AB_10898028)
  
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sciencedirect.com/science/article/pii/S2451945621003962
Nov 2018
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Hypoxic Induction of Vasorin Regulates Notch1 Turnover to Maintain Glioma Stem-like Cells

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1. scibot 05 Nov 2018
  
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  (Cell Signaling Technology Cat# 7096S, RRID:AB_10898028)
  
  SciCrunch record: RRID:AB_10898028
  
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sciencedirect.com/science/article/pii/S1934590917304228