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mTORC1 suppression by Trp53 mutation drives resistance to immune checkpoint blockade

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pmc.ncbi.nlm.nih.gov/articles/PMC13620114/
Sep 2026
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Evolution of SPP1+ cavity macrophage-mediated immunotherapy resistance in peritoneal metastasis of colorectal cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC13522804/
Aug 2026
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A macrophage-intestinal organoid co-culture model captures balanced epithelial homeostasis and inflammation

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sciencedirect.com/science/article/pii/S2213671126002560
Jul 2026
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Engineering oral commensal nanovaccines to activate mucosal-systemic immune cascades against tumor

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Targeting p21-High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

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  DOI: 10.1002/advs.76384
  
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advanced.onlinelibrary.wiley.com/doi/10.1002/advs.76384
Jun 2026
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BPS Publications

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YB-1 inhibition suppresses osteosarcoma growth and reverses tumor immunosuppression

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STAT3 interference-driven nanomodulators reverse lipid metabolism-associated chemoresistance and potentiate metalloimmunotherapy in breast cancer

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Targeting the macrophage mechanosensing regulator CKAP4 accelerates the inflammatory-to-proliferative transition in wound healing

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sciencedirect.com/science/article/pii/S2211124726004730
May 2026
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IL-1R2 Deficiency Unleashes Neutrophil-Mediated Antitumor Potential in Sarcoma

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aacrjournals.org/cancerimmunolres/article/14/5/751/784456/IL1R2-Deficiency-Unleashes-Neutrophil-Mediated
Apr 2026
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Tumor-intrinsic FDFT1 determines coordinated macrophage anti-tumor immunity

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1. scibot 30 Apr 2026
  
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Dual-targeted microspheres reshape the metabolic-immune microenvironment to reverse post-embolization dilemmas in hepatocellular carcinoma

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Integrated analysis of stemness-associated immune modulatory circuits in squamous cell carcinomas

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1. scibot 10 Apr 2026
  
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  DOI: 10.64898/2026.04.02.716182
  
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biorxiv.org/content/10.64898/2026.04.02.716182v1
Mar 2026
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Synthetic M13 phage engagers expand CAR-T cell antigen recognition to overcome tumor heterogeneity

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sciencedirect.com/science/article/pii/S0167779926000478
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RORγt Inhibition Reduces Pro-Tumor Inflammation and Decreases Tumor Growth in Experimental Models of Lung Cancer

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  DOI: 10.1158/2326-6066.CIR-24-1128
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12288671/
Feb 2026
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Sensory neuron production of substance P and TAFA4 promotes disease tolerance during viral infection

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1. scibot 26 Feb 2026
  
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  DOI: 10.1016/j.immuni.2026.01.022
  
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Hepatocyte PLAGL2 deficiency alleviates MASH through MYD88-licensed inactivation of inflammasome

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1. scibot 20 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.116942
  
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sciencedirect.com/science/article/pii/S2211124726000203
Dec 2025
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BPS Publications

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1. scibot 06 Dec 2025
  
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  DOI: 10.1111/bph.70277
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70277
Oct 2025
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Cannabidivarin directly targets the immunosuppressive activity of regulatory myeloid cells in tumors

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1. scibot 28 Oct 2025
  
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sciencedirect.com/science/article/pii/S0753332225008911
Sep 2025
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Adoptive macrophages suppress glioblastoma growth by reversing immunosuppressive microenvironment through programmed phenotype repolarization

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Synergically enhanced anti-tumor immunity of in vivo panCAR by circRNA vaccine boosting

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pmc.ncbi.nlm.nih.gov/articles/PMC12432353/
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Sensory neurons shape local macrophage identity via TGF-β signaling

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Aug 2025
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CHI3L3+ immature neutrophils inhibit anti-tumor immunity and impede immune checkpoint blockade therapy in bone metastases

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  DOI: 10.1016/j.ccell.2025.07.007
  
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Interleukin-4 induces CD11c+ microglia leading to amelioration of neuropathic pain in mice

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  DOI: 10.7554/eLife.105087
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12316456/
Jul 2025
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Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity

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May 2025
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Tumor microenvironment-associated oxidative stress impairs SIRT1 secretion to suppress anti-tumor immune response

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Jan 2025
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The bacterial microbiome modulates the initiation of brain metastasis by impacting the gut-to-brain axis

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52.53.155.43/7d89da942243a2eaf4b37b3c4318db932749cf0d/1-s2.0-S2589004225001348-main-html.html
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Phenotypic plasticity and increased infiltration of peripheral blood-derived TREM1+ mono-macrophages following radiotherapy in rectal cancer

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Nov 2024
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can-24-1817-html.html

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52.53.155.43/65dca824591f5654591dc592fd6476e0cd35e8bf/can-24-1817-html.html
Sep 2024
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Myeloid beta-arrestin 2 depletion attenuates metabolic dysfunction-associated steatohepatitis via the metabolic reprogramming of macrophages

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Tumour-associated mesenchymal stromal cells modulate macrophage phagocytosis in stromal-rich colorectal cancer via PD-1 signalling.

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Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell

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Type I interferon signaling regulates myeloid and T cell crosstalk in the glioblastoma tumor microenvironment

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pmc.ncbi.nlm.nih.gov/articles/PMC11404196/
Aug 2024
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Artificial mucus layer formed in response to ROS for the oral treatment of inflammatory bowel disease

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  DOI: 10.1126/sciadv.ado8222
  
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science.org/doi/10.1126/sciadv.ado8222
Jul 2024
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Artificial mucus layer formed in response to ROS for the oral treatment of inflammatory bowel disease

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  DOI: 10.1126/sciadv.ado8222
  
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Investigation of a fluorescent reporter microenvironment niche labeling strategy in experimental brain metastasis

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Engineering an energy-dissipating hybrid tissue in vivo for obesity treatment

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Tumour microenvironment programming by an RNA–RNA-binding protein complex creates a druggable vulnerability in IDH-wild-type glioblastoma

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Macrophage-coated tumor cluster aggravates hepatoma invasion and immunotherapy resistance via generating local immune deprivation

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Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells

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Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity

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Rebalancing liver-infiltrating CCR3+ and CD206+ monocytes improves diet-induced NAFLD

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Engineer a double team of short-lived and glucose-sensing bacteria for cancer eradication

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Tissue-specific metabolic profile drives iNKT cell function during obesity and liver injury

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Targeted Rejuvenation of Exhausted Chimeric Antigen Receptor T-cells Regresses Refractory Solid Tumors

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Maintenance of glutamine synthetase expression alleviates endotoxin-induced sepsis via alpha-ketoglutarate-mediated demethylation

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BPS Publications

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A20 deficiency in myeloid cells protects mice from diet-induced obesity and insulin resistance due to increased fatty acid metabolism

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Isolation of mouse Kupffer cells for phenotypic and functional studies

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Senescent immune cells release grancalcin to promote skeletal aging

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A subset of Kupffer cells regulates metabolism through the expression of CD36

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Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming

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Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy

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Untitled document

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  DOI: 10.1016/j.ccell.2017.03.006
  
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May 2021
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Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection

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Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver

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Innate Lymphoid Cells in the Induction of Obesity

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Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis

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Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression

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