54 Matching Annotations
  1. Aug 2024
  2. jbiomedsci.biomedcentral.com jbiomedsci.biomedcentral.com
    Proteasome inhibitors restore the STAT1 pathway and enhance the expression of MHC class I on human colon cancer cells
    1
    1. scibot 02 Aug 2024
      8478

      DOI: 10.1186/s12929-021-00769-9

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    jbiomedsci.biomedcentral.com/articles/10.1186/s12929-021-00769-9
  3. Jul 2024
  4. www.sciencedirect.com www.sciencedirect.com
    The canonical antiviral protein oligoadenylate synthetase 1 elicits antibacterial functions by enhancing IRF1 translation
    1
    1. scibot 19 Jul 2024
      AB_10949108

      DOI: 10.1016/j.immuni.2024.06.003

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    sciencedirect.com/science/article/pii/S1074761324003091
  5. Jun 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dynamic control of gene expression by ISGF3 and IRF1 during IFNβ and IFNγ signaling
    1
    1. scibot 08 Jun 2024
      RRID:AB_10949108

      DOI: 10.1038/s44318-024-00092-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC11148166/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity
    1
    1. scibot 04 Jun 2024
      RRID:AB_10949108

      DOI: 10.1016/j.celrep.2024.114289

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    ncbi.nlm.nih.gov/pmc/articles/PMC11315447/
  8. www.sciencedirect.com www.sciencedirect.com
    IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility
    1
    1. scibot 02 Jun 2024
      RRID:AB_10949108

      DOI: 10.1016/j.celrep.2021.108891

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    sciencedirect.com/science/article/pii/S2211124721002059
  9. Mar 2024
  10. www.sciencedirect.com www.sciencedirect.com
    SMARCA4 is a haploinsufficient B cell lymphoma tumor suppressor that fine-tunes centrocyte cell fate decisions
    2
    1. scibot 08 Mar 2024
      RRID:AB_10949108

      DOI: 10.1016/j.ccell.2024.02.011

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    2. scibot 08 Mar 2024
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    sciencedirect.com/science/article/pii/S1535610824000552
  11. www.sciencedirect.com www.sciencedirect.com
    Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon
    2
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.devcel.2024.02.005

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    2. scibot 06 Mar 2024
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    sciencedirect.com/science/article/pii/S1534580724000765
  12. Feb 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Dietary elaidic acid boosts tumoral antigen presentation and cancer immunity via ACSL5
    2
    1. scibot 14 Feb 2024
      RRID:AB_10949108

      DOI: 10.1016/j.cmet.2024.01.012

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    2. scibot 13 Feb 2024
      RRID:AB_10949108

      DOI: 10.1016/j.cmet.2024.01.012

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    sciencedirect.com/science/article/pii/S1550413124000123
  14. Nov 2023
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
    2
    1. scibot 04 Nov 2023
      RRID:AB_10949108

      DOI: 10.1126/science.adh5021

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    2. scibot 04 Nov 2023
      RRID:AB_10949108

      DOI: 10.1126/science.adh5021

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    ncbi.nlm.nih.gov/pmc/articles/PMC10617673/
  16. Oct 2023
  17. www.science.org www.science.org
    The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
    1
    1. scibot 17 Oct 2023
      RRID:AB_10949108

      DOI: 10.1126/science.adh5021

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    science.org/doi/10.1126/science.adh5021
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
    1
    1. scibot 14 Oct 2023
      RRID:AB_10949108

      DOI: 10.1016/j.xcrm.2023.101214

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    pmc.ncbi.nlm.nih.gov/articles/PMC10591052/
  19. www.sciencedirect.com www.sciencedirect.com
    High-throughput identification of Toxoplasma gondii effector proteins that target host cell transcription
    1
    1. scibot 13 Oct 2023
      RRID:AB_10949108

      DOI: 10.1016/j.chom.2023.09.003

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    sciencedirect.com/science/article/pii/S1931312823003700
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor–Positive Breast Cancer
    1
    1. scibot 06 Oct 2023
      RRID:AB_10949108

      DOI: 10.1158/0008-5472.CAN-23-1711

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    ncbi.nlm.nih.gov/pmc/articles/PMC10543960/
  21. Jul 2023
  22. www.sciencedirect.com www.sciencedirect.com
    MEF2A suppresses stress responses that trigger DDX41-dependent IFN production
    1
    1. scibot 21 Jul 2023
      RRID:AB_10949108

      DOI: 10.1016/j.celrep.2023.112805

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    sciencedirect.com/science/article/pii/S2211124723008161
  23. Jun 2023
  24. www.sciencedirect.com www.sciencedirect.com
    NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs
    1
    1. scibot 02 Jun 2023
      RRID:AB_10949108

      DOI: 10.1016/j.cell.2023.05.005

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    sciencedirect.com/science/article/pii/S009286742300524X
  25. May 2023
  26. www.mdpi.com www.mdpi.com
    Comparative Analysis of Six IRF Family Members in Alveolar Epithelial Cell-Intrinsic Antiviral Responses
    1
    1. scibot 06 May 2023
      RRID: AB_10949108

      DOI: 10.3390/cells10102600

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    mdpi.com/2073-4409/10/10/2600/htm
  27. Apr 2023
  28. www.sciencedirect.com www.sciencedirect.com
    MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer
    1
    1. scibot 12 Apr 2023
      RRID:AB_10949108

      DOI: 10.1016/j.xcrm.2023.101006

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    sciencedirect.com/science/article/pii/S2666379123001167
  29. www.nature.com www.nature.com
    Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy
    1
    1. scibot 11 Apr 2023
      RRID:AB_10949108

      DOI: 10.1038/s41467-023-37617-3

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    nature.com/articles/s41467-023-37617-3
  30. Feb 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria
    1
    1. scibot 03 Feb 2023
      RRID:AB_10949108

      DOI: 10.1016/j.cell.2022.12.038

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    sciencedirect.com/science/article/pii/S0092867422015811
  32. Nov 2022
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Manganese enhances DNA- or RNA-mediated innate immune response by inducing phosphorylation of TANK-binding kinase 1
    1
    1. scibot 04 Nov 2022
      RRID:AB_10949108

      DOI: 10.1016/j.isci.2022.105352

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    ncbi.nlm.nih.gov/pmc/articles/PMC9619380/
  34. Aug 2022
  35. www.sciencedirect.com www.sciencedirect.com
    Cancer genes disfavoring T cell immunity identified via integrated systems approach
    1
    1. scibot 06 Aug 2022
      RRID:AB_10949108

      DOI: 10.1016/j.celrep.2022.111153

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    sciencedirect.com/science/article/pii/S2211124722009627
  36. Jun 2022
  37. 52.53.155.43 52.53.155.43
    cd-21-1022-html.html
    3
    1. scibot 30 Jun 2022
      RRID:AB_10949108

      DOI: 10.1158/2159-8290.CD-21-1022

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    2. scibot 25 Jun 2022
      RRID:AB_10949108

      DOI: 10.1158/2159-8290.cd-21-1022

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    3. scibot 25 Jun 2022
      RRID:AB_10949108

      DOI: 10.1158/2159-8290.cd-21-1022

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    52.53.155.43/dae3a722cb0f412060233d3b16799226aa47507e/cd-21-1022-html.html
  38. Apr 2022
  39. www.sciencedirect.com www.sciencedirect.com
    EMT alterations in the solute carrier landscape uncover SLC22A10/A15 imposed vulnerabilities in pancreatic cancer
    1
    1. scibot 15 Apr 2022
      RRID:AB_10949108

      DOI: 10.1016/j.isci.2022.104193

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    sciencedirect.com/science/article/pii/S2589004222004631
  40. Mar 2022
  41. www.sciencedirect.com www.sciencedirect.com
    CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4
    1
    1. scibot 02 Mar 2022
      RRID:AB_10949108

      DOI: 10.1016/j.ccell.2022.02.003

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    sciencedirect.com/science/article/pii/S1535610822000368
  42. Feb 2022
  43. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction
    1
    1. scibot 23 Feb 2022
      RRID:AB_10949108

      DOI: 10.1016/j.celrep.2022.110420

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    pubmed.ncbi.nlm.nih.gov/35196494/
  44. www.sciencedirect.com www.sciencedirect.com
    Poxviruses and paramyxoviruses use a conserved mechanism of STAT1 antagonism to inhibit interferon signaling
    1
    1. scibot 23 Feb 2022
      RRID:AB_10949108

      DOI: 10.1016/j.chom.2022.01.014

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    sciencedirect.com/science/article/pii/S1931312822000506
  45. Jan 2022
  46. elifesciences.org elifesciences.org
    Overexpression screen of interferon-stimulated genes identifies RARRES3 as a restrictor of Toxoplasma gondii infection
    1
    1. scibot 29 Jan 2022
      RRID:AB_10949108

      DOI: 10.7554/eLife.73137

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    elifesciences.org/articles/73137
  47. Aug 2021
  48. www.sciencedirect.com www.sciencedirect.com
    Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis
    1
    1. scibot 16 Aug 2021
      RRID:AB_10949108

      DOI: 10.1016/j.isci.2021.102845

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    sciencedirect.com/science/article/pii/S2589004221008130
  49. www.sciencedirect.com www.sciencedirect.com
    Reshaping of the Dendritic Cell Chromatin Landscape and Interferon Pathways during HIV Infection
    1
    1. scibot 04 Aug 2021
      RRID:AB_10949108

      DOI: 10.1016/j.chom.2018.01.012

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    sciencedirect.com/science/article/pii/S1931312818300477
  50. Jul 2021
  51. www.embopress.org www.embopress.org
    A genome‐wide screen identifies IRF2 as a key regulator of caspase‐4 in human cells
    1
    1. scibot 29 Jul 2021
      rabbit monoclonal anti‐IRF1

      DOI: 10.15252/embr.201948235

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    embopress.org/doi/full/10.15252/embr.201948235
  52. elifesciences.org elifesciences.org
    A comprehensive analysis of coregulator recruitment, androgen receptor function and gene expression in prostate cancer
    1
    1. scibot 27 Jul 2021
      8478S

      DOI: 10.7554/eLife.28482

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    elifesciences.org/articles/28482
  53. Jun 2021
  54. www.sciencedirect.com www.sciencedirect.com
    A PGE2-MEF2A axis enables context-dependent control of inflammatory gene expression
    1
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      RRID:AB_10949108

      DOI: 10.1016/j.immuni.2021.05.016

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    sciencedirect.com/science/article/pii/S1074761321002223
  55. May 2021
  56. www.sciencedirect.com www.sciencedirect.com
    Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation
    1
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      RRID:AB_10949108

      DOI: 10.1016/j.molcel.2021.01.010

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    sciencedirect.com/science/article/pii/S1097276521000101
  57. Apr 2021
  58. www.sciencedirect.com www.sciencedirect.com
    NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion
    1
    1. scibot 30 Apr 2021
      RRID:AB_10949108

      DOI: 10.1016/j.cmet.2020.10.021

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    sciencedirect.com/science/article/pii/S1550413120305544
  59. Mar 2021
  60. www.sciencedirect.com www.sciencedirect.com
    IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility
    1
    1. scibot 24 Mar 2021
      RRID:AB_10949108

      DOI: 10.1016/j.celrep.2021.108891

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    sciencedirect.com/science/article/pii/S2211124721002059
  61. Feb 2021
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer
    1
    1. scibot 26 Feb 2021
      RRID:AB_10949108

      DOI: 10.7554/eLife.58810

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    ncbi.nlm.nih.gov/pmc/articles/PMC7447441/
  63. Nov 2020
  64. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Activation of Clustered IFNγ Target Genes Drives Cohesin-Controlled Transcriptional Memory
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      RRID:AB_10949108

      DOI: 10.1016/j.molcel.2020.10.005

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  65. Sep 2020
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell RNA-sequencing reveals distinct patterns of cell state heterogeneity in mouse models of breast cancer
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      DOI: 10.7554/eLife.58810

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    ncbi.nlm.nih.gov/pmc/articles/PMC7447441/
  67. Jan 2020
  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Decreased levels of constitutive proteasomes in experimental autoimmune encephalomyelitis may be caused by a combination of subunit displacement and reduced Nfe2l1 expression
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      AB_10949108

      DOI: 10.1111/jnc.14912

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14912
  69. www.sciencedirect.com www.sciencedirect.com
    An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer
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    1. scibot 13 Jan 2020
      RRID:AB_10949108

      DOI: 10.1016/j.ccell.2019.08.008

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    sciencedirect.com/science/article/pii/S1535610819303769
  70. www.sciencedirect.com www.sciencedirect.com
    The Cytoplasmic DNA Sensor cGAS Promotes Mitotic Cell Death
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      RRID:AB_10949108

      DOI: 10.1016/j.cell.2019.05.035

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    sciencedirect.com/science/article/pii/S009286741930563X
  71. www.sciencedirect.com www.sciencedirect.com
    Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and III Interferons
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    1. scibot 13 Jan 2020
      RRID:AB_10949108

      DOI: 10.1016/j.immuni.2019.07.007

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    sciencedirect.com/science/article/pii/S1074761319303231
  72. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions
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    1. scibot 13 Jan 2020
      RRID:AB_10949108

      DOI: 10.1016/j.molcel.2019.07.034

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    sciencedirect.com/science/article/pii/S1097276519305891
  73. www.nature.com www.nature.com
    IL-36 promotes anti-viral immunity by boosting sensitivity to IFN-α/β in IRF1 dependent and independent manners
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      DOI: 10.1038/s41467-019-12318-y

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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.7554/eLife.41159

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    ncbi.nlm.nih.gov/pmc/articles/PMC6389286/
  75. www.sciencedirect.com www.sciencedirect.com
    The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons
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      RRID:AB_10949108

      DOI: 10.1016/j.immuni.2018.11.017

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    sciencedirect.com/science/article/pii/S1074761318305259
  76. Nov 2018
  77. www.sciencedirect.com www.sciencedirect.com
    An Antiviral Branch of the IL-1 Signaling Pathway Restricts Immune-Evasive Virus Replication
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  78. Nov 2017
  79. www.sciencedirect.com www.sciencedirect.com
    IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes
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    sciencedirect.com/science/article/pii/S0092867416312454