99 Matching Annotations
  1. Jul 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication
    1
    1. scibot 14 Jul 2024
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      DOI: 10.1016/j.isci.2024.110144

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    ncbi.nlm.nih.gov/pmc/articles/PMC11233922/
  3. Jun 2024
  4. www.sciencedirect.com www.sciencedirect.com
    CRISPR activation screens identify the SWI/SNF ATPases as suppressors of ferroptosis
    1
    1. scibot 21 Jun 2024
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    sciencedirect.com/science/article/pii/S2211124724006739
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    Inhibition of HDAC activity directly reprograms murine embryonic stem cells to trophoblast stem cells
    1
    1. scibot 04 Jun 2024
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    sciencedirect.com/science/article/pii/S1534580724003265
  6. May 2024
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    Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng
    2
    1. scibot 31 May 2024
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      DOI: 10.1016/j.immuni.2024.05.006

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    2. scibot 31 May 2024
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      DOI: 10.1016/j.immuni.2024.05.006

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    sciencedirect.com/science/article/pii/S1074761324002590
  8. www.nature.com www.nature.com
    Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer
    1
    1. scibot 30 May 2024
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      DOI: 10.1038/s41416-024-02697-5

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    nature.com/articles/s41416-024-02697-5
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    Single-cell multiomics profiling reveals heterogeneous transcriptional programs and microenvironment in DSRCTs
    1
    1. scibot 23 May 2024
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    sciencedirect.com/science/article/pii/S266637912400274X
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    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
    1
    1. scibot 14 May 2024
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      DOI: 10.1016/j.cell.2024.04.023

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    sciencedirect.com/science/article/pii/S0092867424004483
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    Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma
    1
    1. scibot 09 May 2024
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    sciencedirect.com/science/article/pii/S2211124724005394
  12. Apr 2024
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    The Drosophila Hippo pathway transcription factor Scalloped and its co-factors alter each other’s chromatin binding dynamics and transcription in vivo
    1
    1. scibot 26 Apr 2024
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    sciencedirect.com/science/article/pii/S1534580724002314
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    Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity
    2
    1. scibot 18 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724004224
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    SP6 controls human cytotrophoblast fate decisions and trophoblast stem cell establishment by targeting MSX2 regulatory elements
    1
    1. scibot 09 Apr 2024
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    sciencedirect.com/science/article/pii/S153458072400193X
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    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
    1
    1. scibot 05 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724003930
  17. Mar 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
    1
    1. scibot 29 Mar 2024
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      DOI: 10.1016/j.molcel.2024.02.032

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    sciencedirect.com/science/article/pii/S1097276524001758
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    Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice
    2
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113875

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    sciencedirect.com/science/article/pii/S2211124724002031
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    Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability
    2
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.cmet.2024.02.004

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    sciencedirect.com/science/article/pii/S1550413124000500
  21. Feb 2024
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    Canonical Wnt signaling directs the generation of functional human PSC-derived atrioventricular canal cardiomyocytes in bioprinted cardiac tissues
    1
    1. scibot 24 Feb 2024
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      DOI: 10.1016/j.stem.2024.01.008

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    sciencedirect.com/science/article/pii/S1934590924000389
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    Selection of epigenetically privileged HIV-1 proviruses during treatment with panobinostat and interferon-α2a
    2
    1. scibot 21 Feb 2024
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      DOI: 10.1016/j.cell.2024.01.037

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      DOI: 10.1016/j.cell.2024.01.037

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    sciencedirect.com/science/article/pii/S0092867424001053
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    Lactic acid induces transcriptional repression of macrophage inflammatory response via histone acetylation
    1
    1. scibot 09 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113746

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    sciencedirect.com/science/article/pii/S2211124724000743
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    H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in pediatric high-grade glioma cells
    2
    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113707

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      DOI: 10.1016/j.celrep.2024.113707

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    sciencedirect.com/science/article/pii/S2211124724000354
  26. Jan 2024
  27. www.sciencedirect.com www.sciencedirect.com
    Lysine acetyltransferase 6A maintains CD4+ T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.cmet.2023.12.016

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    sciencedirect.com/science/article/pii/S1550413123004679
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-15-dependent immune crosstalk between natural killer cells and dendritic cells in HIV-1 elite controllers
    1
    1. scibot 12 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113530

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    ncbi.nlm.nih.gov/pmc/articles/PMC10765318/
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    Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113575

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    sciencedirect.com/science/article/pii/S2211124723015875
  30. Dec 2023
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions
    1
    1. scibot 02 Dec 2023
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      DOI: 10.1016/j.isci.2023.108446

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    ncbi.nlm.nih.gov/pmc/articles/PMC10687339/
  32. www.science.org www.science.org
    KDM6B drives epigenetic reprogramming associated with lymphoid stromal cell early commitment and immune properties
    2
    1. scibot 02 Dec 2023
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      DOI: 10.1126/sciadv.adh2708

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      DOI: 10.1126/sciadv.adh2708

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    science.org/doi/10.1126/sciadv.adh2708
  33. Oct 2023
  34. 52.53.155.43 52.53.155.43
    PIIS0092867423009650-html.html
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    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.cell.2023.08.032

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  35. Sep 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Discordant interactions between YAP1 and polycomb group protein SCML2 determine cell fate
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.isci.2023.107964

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    sciencedirect.com/science/article/pii/S2589004223020412
  37. Aug 2023
  38. www.sciencedirect.com www.sciencedirect.com
    The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function
    1
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      DOI: 10.1016/j.celrep.2023.113013

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    sciencedirect.com/science/article/pii/S2211124723010240
  39. 52.53.155.43 52.53.155.43
    NFYC-37 promotes tumor growth by activating the mevalonate pathway in bladder cancer
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      DOI: 10.1016/j.celrep.2023.112963

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    52.53.155.43/eb7aace05cf7a189f4453bfbeb3bcf344412f769/mmc4-html.html
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    Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer
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    sciencedirect.com/science/article/pii/S1535610823002453
  41. Jul 2023
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    Ketolysis drives CD8+ T cell effector function through effects on histone acetylation
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      DOI: 10.1016/j.immuni.2023.07.002

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    sciencedirect.com/science/article/pii/S107476132300314X
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    A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression
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    sciencedirect.com/science/article/pii/S2211124723008446
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    Single-cell dissection of Merkel cell carcinoma heterogeneity unveils transcriptomic plasticity and therapeutic vulnerabilities
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    sciencedirect.com/science/article/pii/S2666379123002203
  45. Jun 2023
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    Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation
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    sciencedirect.com/science/article/pii/S1074761323002273
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    Complex regulation of Eomes levels mediated through distinct functional features of the Meteor long non-coding RNA locus
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    sciencedirect.com/science/article/pii/S2211124723005806
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    (A) Elevated expression of histone deacetylase HDAC8 suppresses arginine-proline metabolism in necrotizing enterocolitis
    1
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    Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling
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      DOI: 10.1016/j.celrep.2020.108333

      Resource: (Cell Signaling Technology Cat# 8173, RRID:AB_10949503)

      Curator: @Naa003

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    sciencedirect.com/science/article/pii/S221112472031322X
  110. Oct 2020
  111. www.sciencedirect.com www.sciencedirect.com
    Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors
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    1. scibot 27 Oct 2020
      RRID:AB_10949503

      DOI: 10.1016/j.chembiol.2020.10.001

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    sciencedirect.com/science/article/pii/S2451945620303809
  112. Sep 2020
  113. www.sciencedirect.com www.sciencedirect.com
    Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells
    1
    1. scibot 26 Sep 2020
      RRID:AB_10949503

      DOI: 10.1016/j.molcel.2020.03.010

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    sciencedirect.com/science/article/pii/S1097276520301581
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Diverse nucleosome Site-Selectivity among histone deacetylase complexes
    1
    1. scibot 16 Sep 2020
      RRID:AB_10949503

      DOI: 10.7554/eLife.57663

      Resource: (Cell Signaling Technology Cat# 8173, RRID:AB_10949503)

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    ncbi.nlm.nih.gov/pmc/articles/PMC7316510/
  115. www.sciencedirect.com www.sciencedirect.com
    Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution
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    1. scibot 15 Sep 2020
      RRID:AB_2616015

      DOI: 10.1016/j.molcel.2020.05.025

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    sciencedirect.com/science/article/pii/S1097276520303452
  116. www.sciencedirect.com www.sciencedirect.com
    NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma
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    1. scibot 08 Sep 2020
      RRID:AB_10949503

      DOI: 10.1016/j.celrep.2020.107782

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    sciencedirect.com/science/article/pii/S2211124720307622
  117. www.sciencedirect.com www.sciencedirect.com
    Chromatin Hyperacetylation Impacts Chromosome Folding by Forming a Nuclear Subcompartment
    1
    1. scibot 08 Sep 2020
      RRID:AB_10949503

      DOI: 10.1016/j.molcel.2020.03.018

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    sciencedirect.com/science/article/pii/S1097276520301866
  118. Jan 2020
  119. www.sciencedirect.com www.sciencedirect.com
    One-Carbon Metabolism Supports S-Adenosylmethionine and Histone Methylation to Drive Inflammatory Macrophages
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949503

      DOI: 10.1016/j.molcel.2019.06.039

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    sciencedirect.com/science/article/pii/S1097276519304964
  120. www.sciencedirect.com www.sciencedirect.com
    Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949887

      DOI: 10.1016/j.cell.2019.08.013

      Resource: (Cell Signaling Technology Cat# 8173, RRID:AB_10949503)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S0092867419309018
  121. www.sciencedirect.com www.sciencedirect.com
    Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949503

      DOI: 10.1016/j.cell.2019.07.048

      Resource: (Cell Signaling Technology Cat# 8173, RRID:AB_10949503)

      Curator: @ethanbadger

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      RRID:AB_10949503 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867419308487
  122. www.sciencedirect.com www.sciencedirect.com
    A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949503

      DOI: 10.1016/j.celrep.2019.10.011

      Resource: (Cell Signaling Technology Cat# 8173, RRID:AB_10949503)

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    sciencedirect.com/science/article/pii/S2211124719313117
  123. www.sciencedirect.com www.sciencedirect.com
    p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949503

      DOI: 10.1016/j.celrep.2019.07.027

      Resource: (Cell Signaling Technology Cat# 8173, RRID:AB_10949503)

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    sciencedirect.com/science/article/pii/S2211124719309246
  124. www.sciencedirect.com www.sciencedirect.com
    The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949503

      DOI: 10.1016/j.immuni.2018.12.018

      Resource: (Cell Signaling Technology Cat# 8173, RRID:AB_10949503)

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S1074761318305661
  125. www.sciencedirect.com www.sciencedirect.com
    LRH1-driven transcription factor circuitry for hepatocyte identity: Super-enhancer cistromic analysis
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949503

      DOI: 10.1016/j.ebiom.2018.12.056

      Resource: (Cell Signaling Technology Cat# 8173, RRID:AB_10949503)

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S2352396418306339
  126. Nov 2018
  127. www.sciencedirect.com www.sciencedirect.com
    Mutant NPM1 Maintains the Leukemic State through HOX Expression
    1
    1. scibot 05 Nov 2018
      RRID:AB_10949503

      Curator: @Jmenke

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      (Cell Signaling Technology Cat# 8173S, RRID:AB_10949503)

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    sciencedirect.com/science/article/pii/S1535610818303593
  128. www.sciencedirect.com www.sciencedirect.com
    SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function
    1
    1. scibot 05 Nov 2018
      RRID:AB_10949503

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    sciencedirect.com/science/article/pii/S1934590918303850
  129. www.sciencedirect.com www.sciencedirect.com
    A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer
    1
    1. scibot 05 Nov 2018
      RRID:AB_10949503

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      (Cell Signaling Technology Cat# 8173S, RRID:AB_10949503)

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    sciencedirect.com/science/article/pii/S0092867418306494