106 Matching Annotations
  1. Sep 2024
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    TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.celrep.2019.05.061

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    sciencedirect.com/science/article/pii/S2211124719306904
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    Promoter DNA methylation and transcription factor condensation are linked to transcriptional memory in mammalian cells
    1
    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.cels.2024.08.007

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    sciencedirect.com/science/article/pii/S2405471224002370
  4. Aug 2024
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    FRA1 controls acinar cell plasticity during murine KrasG12D-induced pancreatic acinar to ductal metaplasia
    1
    1. scibot 23 Aug 2024
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      DOI: 10.1016/j.devcel.2024.07.021

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    sciencedirect.com/science/article/pii/S1534580724004830
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Feedforward cysteine regulation maintains melanoma differentiation state and limits metastatic spread
    1
    1. scibot 21 Aug 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11316253/
  7. Jul 2024
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    Acetyl-CoA metabolism maintains histone acetylation for syncytialization of human placental trophoblast stem cells
    1
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    sciencedirect.com/science/article/pii/S1934590924002534
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    Mammalian SWI/SNF complex activity regulates POU2F3 and constitutes a targetable dependency in small cell lung cancer
    1
    1. scibot 25 Jul 2024
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    sciencedirect.com/science/article/pii/S153561082400237X
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    IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma
    1
    1. scibot 24 Jul 2024
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    sciencedirect.com/science/article/pii/S1535610824002174
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication
    1
    1. scibot 14 Jul 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11233922/
  12. Jun 2024
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    CRISPR activation screens identify the SWI/SNF ATPases as suppressors of ferroptosis
    1
    1. scibot 21 Jun 2024
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    sciencedirect.com/science/article/pii/S2211124724006739
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    Inhibition of HDAC activity directly reprograms murine embryonic stem cells to trophoblast stem cells
    1
    1. scibot 04 Jun 2024
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    sciencedirect.com/science/article/pii/S1534580724003265
  15. May 2024
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    Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng
    2
    1. scibot 31 May 2024
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      DOI: 10.1016/j.immuni.2024.05.006

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    sciencedirect.com/science/article/pii/S1074761324002590
  17. www.nature.com www.nature.com
    Epigenetic activation of SOX11 is associated with recurrence and progression of ductal carcinoma in situ to invasive breast cancer
    1
    1. scibot 30 May 2024
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      DOI: 10.1038/s41416-024-02697-5

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    nature.com/articles/s41416-024-02697-5
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    Single-cell multiomics profiling reveals heterogeneous transcriptional programs and microenvironment in DSRCTs
    1
    1. scibot 23 May 2024
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      DOI: 10.1016/j.xcrm.2024.101582

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    sciencedirect.com/science/article/pii/S266637912400274X
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    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
    1
    1. scibot 14 May 2024
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      DOI: 10.1016/j.cell.2024.04.023

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    sciencedirect.com/science/article/pii/S0092867424004483
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    Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma
    1
    1. scibot 09 May 2024
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      DOI: 10.1016/j.celrep.2024.114211

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    sciencedirect.com/science/article/pii/S2211124724005394
  21. Apr 2024
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    The Drosophila Hippo pathway transcription factor Scalloped and its co-factors alter each other’s chromatin binding dynamics and transcription in vivo
    1
    1. scibot 26 Apr 2024
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    sciencedirect.com/science/article/pii/S1534580724002314
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    Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity
    2
    1. scibot 18 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114094

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      DOI: 10.1016/j.celrep.2024.114094

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    sciencedirect.com/science/article/pii/S2211124724004224
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    SP6 controls human cytotrophoblast fate decisions and trophoblast stem cell establishment by targeting MSX2 regulatory elements
    1
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      DOI: 10.1016/j.devcel.2024.03.025

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    sciencedirect.com/science/article/pii/S153458072400193X
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    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
    1
    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114065

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    sciencedirect.com/science/article/pii/S2211124724003930
  26. Mar 2024
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    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
    1
    1. scibot 29 Mar 2024
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      DOI: 10.1016/j.molcel.2024.02.032

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    sciencedirect.com/science/article/pii/S1097276524001758
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    Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice
    2
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113875

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    sciencedirect.com/science/article/pii/S2211124724002031
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    Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability
    2
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      DOI: 10.1016/j.cmet.2024.02.004

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    sciencedirect.com/science/article/pii/S1550413124000500
  30. Feb 2024
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    Canonical Wnt signaling directs the generation of functional human PSC-derived atrioventricular canal cardiomyocytes in bioprinted cardiac tissues
    1
    1. scibot 24 Feb 2024
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      DOI: 10.1016/j.stem.2024.01.008

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    sciencedirect.com/science/article/pii/S1934590924000389
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    Selection of epigenetically privileged HIV-1 proviruses during treatment with panobinostat and interferon-α2a
    2
    1. scibot 21 Feb 2024
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      DOI: 10.1016/j.cell.2024.01.037

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    sciencedirect.com/science/article/pii/S0092867424001053
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    Lactic acid induces transcriptional repression of macrophage inflammatory response via histone acetylation
    1
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    sciencedirect.com/science/article/pii/S2211124724000743
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    H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in pediatric high-grade glioma cells
    2
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    sciencedirect.com/science/article/pii/S2211124724000354
  35. Jan 2024
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    Lysine acetyltransferase 6A maintains CD4+ T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity
    1
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    sciencedirect.com/science/article/pii/S1550413123004679
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-15-dependent immune crosstalk between natural killer cells and dendritic cells in HIV-1 elite controllers
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10765318/
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    Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression
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    sciencedirect.com/science/article/pii/S2211124723015875
  39. Dec 2023
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mof plays distinct roles in hepatic lipid metabolism under healthy or non-alcoholic fatty liver conditions
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    ncbi.nlm.nih.gov/pmc/articles/PMC10687339/
  41. www.science.org www.science.org
    KDM6B drives epigenetic reprogramming associated with lymphoid stromal cell early commitment and immune properties
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      DOI: 10.1126/sciadv.adh2708

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      DOI: 10.1126/sciadv.adh2708

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    science.org/doi/10.1126/sciadv.adh2708
  42. Oct 2023
  43. 52.53.155.43 52.53.155.43
    PIIS0092867423009650-html.html
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      DOI: 10.1016/j.cell.2023.08.032

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  44. Sep 2023
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    Discordant interactions between YAP1 and polycomb group protein SCML2 determine cell fate
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      DOI: 10.1016/j.isci.2023.107964

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    sciencedirect.com/science/article/pii/S2589004223020412
  46. Aug 2023
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    The two enantiomers of 2-hydroxyglutarate differentially regulate cytotoxic T cell function
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      DOI: 10.1016/j.celrep.2023.113013

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    sciencedirect.com/science/article/pii/S2211124723010240
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    NFYC-37 promotes tumor growth by activating the mevalonate pathway in bladder cancer
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      DOI: 10.1016/j.celrep.2023.112963

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    52.53.155.43/eb7aace05cf7a189f4453bfbeb3bcf344412f769/mmc4-html.html
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    Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer
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  68. Jan 2023
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    Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1
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  73. Dec 2022
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  78. Nov 2022
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  83. Aug 2022
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  85. Jul 2022
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  96. Mar 2022
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  100. Oct 2021
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    Pharmacological preconditioning by TERT inhibitor BIBR1532 confers neuronal ischemic tolerance through TERT-mediated transcriptional reprogramming
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  102. Aug 2021
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    Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements
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  104. Jul 2021
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    Glutamine Metabolism Controls Chondrocyte Identity and Function
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  108. Apr 2021
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    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
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      DOI: 10.1016/j.ccell.2020.07.008

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  110. www.sciencedirect.com www.sciencedirect.com
    The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells
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  111. www.sciencedirect.com www.sciencedirect.com
    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
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      DOI: 10.1016/j.ccell.2020.04.014

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  112. www.sciencedirect.com www.sciencedirect.com
    Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG
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      DOI: 10.1016/j.celrep.2021.108994

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    sciencedirect.com/science/article/pii/S2211124721003089
  113. Feb 2021
  114. www.sciencedirect.com www.sciencedirect.com
    Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants
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      DOI: 10.1016/j.stem.2021.01.016

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  115. Jan 2021
  116. www.sciencedirect.com www.sciencedirect.com
    Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity
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      DOI: 10.1016/j.xcrm.2020.100188

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    sciencedirect.com/science/article/pii/S2666379120302433
  117. Nov 2020
  118. www.sciencedirect.com www.sciencedirect.com
    Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling
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      DOI: 10.1016/j.celrep.2020.108333

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  119. Oct 2020
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    Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors
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  121. Sep 2020
  122. www.sciencedirect.com www.sciencedirect.com
    Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells
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      DOI: 10.1016/j.molcel.2020.03.010

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  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Diverse nucleosome Site-Selectivity among histone deacetylase complexes
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  124. www.sciencedirect.com www.sciencedirect.com
    Tuning Transcription Factor Availability through Acetylation-Mediated Genomic Redistribution
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      DOI: 10.1016/j.molcel.2020.05.025

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    NeuroD1 Dictates Tumor Cell Differentiation in Medulloblastoma
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    Chromatin Hyperacetylation Impacts Chromosome Folding by Forming a Nuclear Subcompartment
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      DOI: 10.1016/j.molcel.2020.03.018

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    sciencedirect.com/science/article/pii/S1097276520301866
  127. Jan 2020
  128. www.sciencedirect.com www.sciencedirect.com
    One-Carbon Metabolism Supports S-Adenosylmethionine and Histone Methylation to Drive Inflammatory Macrophages
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      DOI: 10.1016/j.molcel.2019.06.039

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    sciencedirect.com/science/article/pii/S1097276519304964
  129. www.sciencedirect.com www.sciencedirect.com
    Rapid Generation of Somatic Mouse Mosaics with Locus-Specific, Stably Integrated Transgenic Elements
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      RRID:AB_10949887

      DOI: 10.1016/j.cell.2019.08.013

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  130. www.sciencedirect.com www.sciencedirect.com
    Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet
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      RRID:AB_10949503

      DOI: 10.1016/j.cell.2019.07.048

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    sciencedirect.com/science/article/pii/S0092867419308487
  131. www.sciencedirect.com www.sciencedirect.com
    A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2
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      RRID:AB_10949503

      DOI: 10.1016/j.celrep.2019.10.011

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    sciencedirect.com/science/article/pii/S2211124719313117
  132. www.sciencedirect.com www.sciencedirect.com
    p63 and SOX2 Dictate Glucose Reliance and Metabolic Vulnerabilities in Squamous Cell Carcinomas
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      RRID:AB_10949503

      DOI: 10.1016/j.celrep.2019.07.027

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    sciencedirect.com/science/article/pii/S2211124719309246
  133. www.sciencedirect.com www.sciencedirect.com
    The Short Chain Fatty Acid Butyrate Imprints an Antimicrobial Program in Macrophages
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    1. scibot 13 Jan 2020
      RRID:AB_10949503

      DOI: 10.1016/j.immuni.2018.12.018

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    sciencedirect.com/science/article/pii/S1074761318305661
  134. www.sciencedirect.com www.sciencedirect.com
    LRH1-driven transcription factor circuitry for hepatocyte identity: Super-enhancer cistromic analysis
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    1. scibot 13 Jan 2020
      RRID:AB_10949503

      DOI: 10.1016/j.ebiom.2018.12.056

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    sciencedirect.com/science/article/pii/S2352396418306339
  135. Nov 2018
  136. www.sciencedirect.com www.sciencedirect.com
    Mutant NPM1 Maintains the Leukemic State through HOX Expression
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1535610818303593
  137. www.sciencedirect.com www.sciencedirect.com
    SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function
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    sciencedirect.com/science/article/pii/S1934590918303850
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    A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer
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    sciencedirect.com/science/article/pii/S0092867418306494