68 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission
    1
    1. scibot 16 Apr 2024
      RRID:AB_10950494

      DOI: 10.1016/j.celrep.2021.108883

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    sciencedirect.com/science/article/pii/S2211124721001972
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    NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo
    1
    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.stem.2024.03.003

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    sciencedirect.com/science/article/pii/S1934590924000845
  4. dx.doi.org dx.doi.org
    Wnt16 Promotes Vascular Smooth Muscle Contractile Phenotype and Function via Taz(Wwtr1) Activation in Male LDLR-/- Mice
    1
    1. scibot 04 Apr 2024
      RRID:AB_10950494

      DOI: 10.1210/endocr/bqad192

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    dx.doi.org/10.1210/endocr/bqad192
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defects of renal tubular homeostasis and cystogenesis in the Pkhd1-knockout
    1
    1. scibot 03 Apr 2024
      RRID:AB_10950494

      DOI: 10.1016/j.isci.2024.109487

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    ncbi.nlm.nih.gov/pmc/articles/PMC10973142/
  6. Mar 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TEAD1 is crucial for developmental myelination, Remak bundles, and functional regeneration of peripheral nerves
    1
    1. scibot 27 Mar 2024
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      DOI: 10.7554/eLife.87394

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959528/
  8. Jan 2024
  9. www.science.org www.science.org
    RHOAL57V drives the development of diffuse gastric cancer through IGF1R-PAK1-YAP1 signaling
    3
    1. scibot 20 Jan 2024
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      DOI: 10.1126/scisignal.adg5289

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    2. scibot 12 Jan 2024
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    3. scibot 12 Jan 2024
      RRID:AB_10950494

      DOI: 10.1126/scisignal.adg5289

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    science.org/doi/10.1126/scisignal.adg5289
  10. Sep 2023
  11. www.sciencedirect.com www.sciencedirect.com
    Discordant interactions between YAP1 and polycomb group protein SCML2 determine cell fate
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.isci.2023.107964

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    sciencedirect.com/science/article/pii/S2589004223020412
  12. Aug 2023
  13. www.sciencedirect.com www.sciencedirect.com
    The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway
    1
    1. scibot 05 Aug 2023
      RRID:AB_10950494

      DOI: 10.1016/j.isci.2023.107449

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    sciencedirect.com/science/article/pii/S2589004223015262
  14. Jun 2023
  15. aacrjournals.org aacrjournals.org
    Olig1/2-expressing intermediate lineage progenitors are predisposed to PTEN/p53-loss-induced gliomagenesis and harbor specific therapeutic vulnerabilities
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1158/0008-5472.CAN-22-1577

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    aacrjournals.org/cancerres/article/83/6/890/718574/Olig1-2-Expressing-Intermediate-Lineage
  16. Apr 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload
    1
    1. scibot 15 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112399

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    sciencedirect.com/science/article/pii/S2211124723004102
  18. www.sciencedirect.com www.sciencedirect.com
    Lysine long-chain fatty acylation regulates the TEAD transcription factor
    1
    1. scibot 15 Apr 2023
      RRID:AB_10950494

      DOI: 10.1016/j.celrep.2023.112388

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    sciencedirect.com/science/article/pii/S2211124723003996
  19. www.sciencedirect.com www.sciencedirect.com
    Matrix stiffness regulates tumor cell intravasation through expression and ESRP1-mediated alternative splicing of MENA
    1
    1. scibot 08 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112338

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    sciencedirect.com/science/article/pii/S2211124723003492
  20. Mar 2023
  21. www.embopress.org www.embopress.org
    Two Hippo signaling modules orchestrate liver size and tumorigenesis
    2
    1. scibot 16 Mar 2023
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      DOI: 10.15252/embj.2022112126

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    2. scibot 16 Mar 2023
      RRID:AB_10950494

      DOI: 10.15252/embj.2022112126

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    embopress.org/doi/10.15252/embj.2022112126
  22. www.sciencedirect.com www.sciencedirect.com
    Biophysical forces mediated by respiration maintain lung alveolar epithelial cell fate
    1
    1. scibot 04 Mar 2023
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      DOI: 10.1016/j.cell.2023.02.010

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    sciencedirect.com/science/article/pii/S0092867423001277
  23. Dec 2022
  24. www.science.org www.science.org
    Cross-talk between TSC2 and the extracellular matrix controls pulmonary vascular proliferation and pulmonary hypertension
    1
    1. scibot 13 Dec 2022
      RRID:AB_10950494

      DOI: 10.1126/scisignal.abn2743

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    science.org/doi/10.1126/scisignal.abn2743
  25. Nov 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Multiphase coalescence mediates Hippo pathway activation
    1
    1. scibot 03 Nov 2022
      RRID:AB_10950494

      DOI: 10.1016/j.cell.2022.09.036

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    sciencedirect.com/science/article/pii/S0092867422012557
  27. Aug 2022
  28. www.sciencedirect.com www.sciencedirect.com
    Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers
    1
    1. scibot 31 Aug 2022
      RRID:AB_10950494

      DOI: 10.1016/j.celrep.2022.111296

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    sciencedirect.com/science/article/pii/S2211124722011160
  29. Jul 2022
  30. www.sciencedirect.com www.sciencedirect.com
    Mislocalization of protein kinase A drives pathology in Cushing’s syndrome
    1
    1. scibot 13 Jul 2022
      RRID: AB_10950494

      DOI: 10.1016/j.celrep.2022.111073

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    sciencedirect.com/science/article/pii/S2211124722008713
  31. Jun 2022
  32. www.sciencedirect.com www.sciencedirect.com
    Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia
    1
    1. scibot 08 Jun 2022
      RRID:AB_10950494

      DOI: 10.1016/j.cmet.2022.05.004

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    sciencedirect.com/science/article/pii/S1550413122001863
  33. Apr 2022
  34. www.sciencedirect.com www.sciencedirect.com
    WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy
    1
    1. scibot 20 Apr 2022
      RRID:AB_10950494

      DOI: 10.1016/j.molcel.2022.03.027

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    sciencedirect.com/science/article/pii/S1097276522002659
  35. Mar 2022
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Division of Labor between YAP and TAZ in Non–Small Cell Lung Cancer
    1
    1. scibot 17 Mar 2022
      RRID:AB_10950494

      DOI: 10.1158/0008-5472.CAN-20-0125

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    ncbi.nlm.nih.gov/pmc/articles/PMC8916161/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deprogramming metabolism in pancreatic cancer with a bi-functional GPR55 inhibitor and biased β2 adrenergic agonist
    1
    1. scibot 11 Mar 2022
      RRID:AB_10950494

      DOI: 10.1038/s41598-022-07600-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC8901637/
  38. academic.oup.com academic.oup.com
    Mst1/2 is necessary for satellite cell differentiation to promote muscle regeneration
    1
    1. scibot 02 Mar 2022
      AB_10950494

      DOI: 10.1093/stmcls/sxab010

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    academic.oup.com/stmcls/advance-article/doi/10.1093/stmcls/sxab010/6511691
  39. Jan 2022
  40. www.sciencedirect.com www.sciencedirect.com
    Coordinate control of basal epithelial cell fate and stem cell maintenance by core EMT transcription factor Zeb1
    1
    1. scibot 12 Jan 2022
      RRID:AB_10950494

      DOI: 10.1016/j.celrep.2021.110240

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    sciencedirect.com/science/article/pii/S2211124721017496
  41. Dec 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Substratum stiffness regulates Erk signaling dynamics through receptor-level control
    1
    1. scibot 29 Dec 2021
      RRID:AB_10950494

      DOI: 10.1016/j.celrep.2021.110181

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    sciencedirect.com/science/article/pii/S2211124721016818
  43. Oct 2021
  44. www.sciencedirect.com www.sciencedirect.com
    Pan-cancer analysis of non-coding transcripts reveals the prognostic onco-lncRNA HOXA10-AS in gliomas
    1
    1. scibot 21 Oct 2021
      RRID:AB_10950494

      DOI: 10.1016/j.celrep.2021.109873

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    sciencedirect.com/science/article/pii/S2211124721013401
  45. Aug 2021
  46. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 10 Aug 2021
      RRID:AB_10950494

      DOI: 10.1016/j.cmet.2018.11.017

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    sciencedirect.com/science/article/pii/S1550413118307368
  47. www.mdpi.com www.mdpi.com
    Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC
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    1. scibot 07 Aug 2021
      RRID:AB_10950494

      DOI: 10.3390/ijms20102423

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    mdpi.com/1422-0067/20/10/2423
  48. www.sciencedirect.com www.sciencedirect.com
    Exocyst protein subnetworks integrate Hippo and mTOR signaling to promote virus detection and cancer
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    1. scibot 04 Aug 2021
      RRID:AB_10950494

      DOI: 10.1016/j.celrep.2021.109491

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    sciencedirect.com/science/article/pii/S2211124721009189
  49. Jul 2021
  50. www.sciencedirect.com www.sciencedirect.com
    The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number
    1
    1. scibot 30 Jul 2021
      RRID:AB_10950494

      DOI: 10.1016/j.devcel.2018.09.021

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    sciencedirect.com/science/article/pii/S1534580718307810
  51. www.sciencedirect.com www.sciencedirect.com
    Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity
    1
    1. scibot 22 Jul 2021
      RRID:AB_10950494

      DOI: 10.1016/j.ccell.2021.06.016

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    sciencedirect.com/science/article/pii/S153561082100338X
  52. www.sciencedirect.com www.sciencedirect.com
    Yap/Taz inhibit goblet cell fate to maintain lung epithelial homeostasis
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    1. scibot 14 Jul 2021
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      DOI: 10.1016/j.celrep.2021.109347

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    sciencedirect.com/science/article/pii/S2211124721007233
  53. Jun 2021
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver
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      RRID:AB_10950494

      DOI: 10.1126/sciadv.abf9141

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    ncbi.nlm.nih.gov/pmc/articles/PMC8177709/
  55. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    G protein-coupled receptors can control the Hippo/YAP pathway through Gq signaling
    1
    1. scibot 17 Jun 2021
      RRID:AB_10950494

      DOI: 10.1096/fj.202002159R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202002159R
  56. May 2021
  57. www.sciencedirect.com www.sciencedirect.com
    Differentiated Daughter Cells Regulate Stem Cell Proliferation and Fate through Intra-tissue Tension
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    1. scibot 09 May 2021
      RRID:AB_10950494

      DOI: 10.1016/j.stem.2020.11.002

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    sciencedirect.com/science/article/pii/S1934590920305403
  58. Apr 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations
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    1. scibot 30 Apr 2021
      RRID:AB_10950494

      DOI: 10.1016/j.ccell.2021.03.012

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    sciencedirect.com/science/article/pii/S1535610821001707
  60. www.sciencedirect.com www.sciencedirect.com
    Localized EMT reprograms glial progenitors to promote spinal cord repair
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    1. scibot 17 Apr 2021
      RRID:AB_10950494

      DOI: 10.1016/j.devcel.2021.01.017

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    sciencedirect.com/science/article/pii/S1534580721000757
  61. www.sciencedirect.com www.sciencedirect.com
    Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer
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    1. scibot 17 Apr 2021
      RRID:AB_10950494

      DOI: 10.1016/j.ccell.2020.05.005

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  62. Mar 2021
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    EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission
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  64. Dec 2020
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2
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  66. Oct 2020
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    A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis
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      DOI: 10.1016/j.celrep.2020.108284

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  68. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Schwannoma development is mediated by Hippo pathway dysregulation and modified by RAS/MAPK signaling
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      DOI: 10.1172/jci.insight.141514

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  69. Sep 2020
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    Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription
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    Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Axon-dependent expression of YAP/TAZ mediates Schwann cell remyelination but not proliferation after nerve injury
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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin
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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recycling endosomes in mature epithelia restrain tumorigenic signaling
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    Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation
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  76. Jan 2020
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    A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis
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  78. www.sciencedirect.com www.sciencedirect.com
    The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma
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      DOI: 10.1016/j.celrep.2019.07.107

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  79. elifesciences.org elifesciences.org
    CCN1 interlinks integrin and Hippo pathway to autoregulate tip cell activity
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    TAZ Is a Negative Regulator of PPARγ Activity in Adipocytes and TAZ Deletion Improves Insulin Sensitivity and Glucose Tolerance
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      DOI: 10.1016/j.cmet.2019.10.003

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  81. www.sciencedirect.com www.sciencedirect.com
    YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression
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      DOI: 10.1016/j.celrep.2019.03.021

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  82. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.cell.2019.01.019

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  84. www.sciencedirect.com www.sciencedirect.com
    OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ
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      DOI: 10.1016/j.molcel.2018.10.030

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  85. Nov 2018
  86. www.sciencedirect.com www.sciencedirect.com
    Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy
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    Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction
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    Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS
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    Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis
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    Differential Expression of NF2 in Neuroepithelial Compartments Is Necessary for Mammalian Eye Development
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  91. Nov 2017
  92. www.sciencedirect.com www.sciencedirect.com
    YAP/TAZ and Hedgehog Coordinate Growth and Patterning in Gastrointestinal Mesenchyme
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    The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity
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    YAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis
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  95. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    LIX1 regulates YAP1 activity and controls the proliferation and differentiation of stomach mesenchymal progenitors
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