62 Matching Annotations
  1. Aug 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression
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    sciencedirect.com/science/article/pii/S1534580724004866
  3. www.mdpi.com www.mdpi.com
    TCF19 Impacts a Network of Inflammatory and DNA Damage Response Genes in the Pancreatic β-Cell
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    mdpi.com/2218-1989/11/8/513/htm
  4. Jul 2024
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    A human commensal-pathogenic fungus suppresses host immunity via targeting TBK1
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    sciencedirect.com/science/article/pii/S1931312824002622
  6. www.cell.com www.cell.com
    Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1-mediated immunity in the liver
    1
    1. scibot 19 Jul 2024
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    cell.com/cell-reports/abstract/S2211-1247(24)00728-9
  7. Jun 2024
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    The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies
    1
    1. scibot 21 Jun 2024
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    sciencedirect.com/science/article/pii/S1074761324002711
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An integrative epigenome-based strategy for unbiased functional profiling of clinical kinase inhibitors
    1
    1. scibot 09 Jun 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11148061/
  10. May 2024
  11. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial RelA empowers mtDNA G-quadruplex formation for hypoxia adaptation in cancer cells
    1
    1. scibot 31 May 2024
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    sciencedirect.com/science/article/pii/S2451945624001818
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    ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity
    1
    1. scibot 21 May 2024
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    sciencedirect.com/science/article/pii/S0092867424004513
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    Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation
    1
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    sciencedirect.com/science/article/pii/S1934590924001425
  14. Apr 2024
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    Endothelial cell expression of a STING gain-of-function mutation initiates pulmonary lymphocytic infiltration
    1
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    sciencedirect.com/science/article/pii/S221112472400442X
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    Oncostatin M signaling drives cancer-associated skeletal muscle wasting
    1
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  17. Mar 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Type I gamma phosphatidylinositol phosphate 5-kinase i5 controls cell sensitivity to interferon
    2
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    sciencedirect.com/science/article/pii/S1534580724000765
  19. Feb 2024
  20. www.sciencedirect.com www.sciencedirect.com
    PRMT1 acts as a suppressor of MHC-I and anti-tumor immunity
    1
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    sciencedirect.com/science/article/pii/S2211124724001591
  21. aacrjournals.org aacrjournals.org
    Engagement of CD99 activates distinct programs in Ewing sarcoma and macrophages
    3
    1. scibot 27 Feb 2024
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      DOI: 10.1158/2326-6066.CIR-23-0440

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    aacrjournals.org/cancerimmunolres/article/12/2/247/733768/Engagement-of-CD99-Activates-Distinct-Programs-in
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    The HIF transcription network exerts innate antiviral activity in neurons and limits brain inflammation
    1
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    sciencedirect.com/science/article/pii/S2211124724001207
  23. Dec 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Apoptosis releases hydrogen sulfide to inhibit Th17 cell differentiation
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    1. scibot 19 Dec 2023
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    sciencedirect.com/science/article/pii/S1550413123004448
  25. Nov 2023
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    Gadd45β is critical for regulation of type I interferon signaling by facilitating G3BP-mediated stress granule formation
    1
    1. scibot 03 Nov 2023
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    sciencedirect.com/science/article/pii/S2211124723013700
  27. Oct 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MEK inhibitors increase the mortality rate in mice with LPS-induced inflammation through IL-12-NO signaling
    1
    1. scibot 18 Oct 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10575927/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
    1
    1. scibot 14 Oct 2023
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      DOI: 10.1016/j.xcrm.2023.101214

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    pmc.ncbi.nlm.nih.gov/articles/PMC10591052/
  30. www.embopress.org www.embopress.org
    Immune–epithelial cell cross-talk enhances antiviral responsiveness to SARS-CoV-2 in children
    1
    1. scibot 13 Oct 2023
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      DOI: 10.15252/embr.202357912

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    embopress.org/doi/full/10.15252/embr.202357912
  31. Aug 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Combating pan-coronavirus infection by indomethacin through simultaneously inhibiting viral replication and inflammatory response
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    1. scibot 27 Aug 2023
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    sciencedirect.com/science/article/pii/S258900422301708X
  33. www.sciencedirect.com www.sciencedirect.com
    Tryptophan metabolism promotes immune evasion in human pancreatic β cells
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    sciencedirect.com/science/article/pii/S2352396423003055
  34. Jul 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
    1
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  36. Jun 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity
    1
    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.cell.2023.05.039

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    sciencedirect.com/science/article/pii/S0092867423005913
  38. www.sciencedirect.com www.sciencedirect.com
    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
    1
    1. scibot 08 Jun 2023
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  39. May 2023
  40. journals.aai.org journals.aai.org
    cGAS Mediates Inflammation by Polarizing Macrophages to M1 Phenotype via the mTORC1 Pathway
    1
    1. scibot 13 May 2023
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      DOI: 10.4049/jimmunol.2200351

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    journals.aai.org/jimmunol/article/210/8/1098/263495/cGAS-Mediates-Inflammation-by-Polarizing
  41. Mar 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive protocols for culturing and molecular biological analysis of IBD patient-derived colon epithelial organoids
    1
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      DOI: 10.3389/fimmu.2023.1097383

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  43. Dec 2022
  44. www.sciencedirect.com www.sciencedirect.com
    Structurally distinct PARP7 inhibitors provide new insights into the function of PARP7 in regulating nucleic acid-sensing and IFN-β signaling
    1
    1. scibot 18 Dec 2022
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    sciencedirect.com/science/article/pii/S2451945622004184
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blockage of Lamin-A/C loss diminishes the pro-inflammatory macrophage response
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      DOI: 10.1016/j.isci.2022.105528

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    ncbi.nlm.nih.gov/pmc/articles/PMC9708799/
  46. Nov 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis
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    sciencedirect.com/science/article/pii/S2352396422004947
  48. Oct 2022
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    Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation
    1
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    sciencedirect.com/science/article/pii/S221112472201275X
  50. Sep 2022
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    Myeloid cell interferon secretion restricts Zika flavivirus infection of developing and malignant human neural progenitor cells
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    sciencedirect.com/science/article/pii/S0896627322008078
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    SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA
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  53. Aug 2022
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-low Induction of Therapy Resistance
    1
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      DOI: 10.1158/1541-7786.MCR-21-0014

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    ncbi.nlm.nih.gov/pmc/articles/PMC8349875/
  55. May 2022
  56. www.sciencedirect.com www.sciencedirect.com
    The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis
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      DOI: 10.1016/j.immuni.2022.04.006

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    sciencedirect.com/science/article/pii/S1074761322001777
  57. Apr 2022
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular Nicotinamide Phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4
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    ncbi.nlm.nih.gov/pmc/articles/PMC8990213/
  59. Mar 2022
  60. www.sciencedirect.com www.sciencedirect.com
    Restriction factor screening identifies RABGAP1L-mediated disruption of endocytosis as a host antiviral defense
    1
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    Kynurenine importation by SLC7A11 propagates anti-ferroptotic signaling
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    sciencedirect.com/science/article/pii/S1097276522001125
  62. Feb 2022
  63. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction
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    1. scibot 23 Feb 2022
      RRID:AB_1095097

      DOI: 10.1016/j.celrep.2022.110420

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  64. Jan 2022
  65. www.sciencedirect.com www.sciencedirect.com
    Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses
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    1. scibot 11 Jan 2022
      RRID:AB_11220426

      DOI: 10.1016/j.molcel.2021.12.006

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    sciencedirect.com/science/article/pii/S1097276521010686
  66. Oct 2021
  67. www.sciencedirect.com www.sciencedirect.com
    ADAR1 restricts ZBP1-mediated immune response and PANoptosis to promote tumorigenesis
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    1. scibot 21 Oct 2021
      RRID:AB_10950970

      DOI: 10.1016/j.celrep.2021.109858

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    sciencedirect.com/science/article/pii/S2211124721013255
  68. Aug 2021
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins
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    1. scibot 14 Aug 2021
      RRID:AB_10950970

      DOI: 10.7554/eLife.44452

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    ncbi.nlm.nih.gov/pmc/articles/PMC6615860/
  70. Jul 2021
  71. www.sciencedirect.com www.sciencedirect.com
    Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING
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    1. scibot 23 Jul 2021
      RRID:AB_10950970

      DOI: 10.1016/j.celrep.2021.109412

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    sciencedirect.com/science/article/pii/S2211124721008251
  72. Jun 2021
  73. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Mutations in the IFNγ-JAK-STAT pathway causing resistance to immune checkpoint inhibitors in melanoma increase sensitivity to oncolytic virus treatment.
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    1. scibot 29 Jun 2021
      RRID:AB_10950970

      DOI: 10.1158/1078-0432.CCR-20-3365

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    clincancerres.aacrjournals.org/content/27/12/3432
  74. May 2021
  75. academic.oup.com academic.oup.com
    A case of Luscan-Lumish syndrome: Possible involvement of enhanced GH signaling
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    1. scibot 10 May 2021
      RRID:AB_10950970

      DOI: 10.1210/clinem/dgaa893

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    academic.oup.com/jcem/article/106/3/718/6009067
  76. www.sciencedirect.com www.sciencedirect.com
    An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
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    1. scibot 06 May 2021
      RRID:AB_10950970

      DOI: 10.1016/j.immuni.2020.06.016

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    sciencedirect.com/science/article/pii/S1074761320302715
  77. Apr 2021
  78. www.sciencedirect.com www.sciencedirect.com
    NAD+ Metabolism Maintains Inducible PD-L1 Expression to Drive Tumor Immune Evasion
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    1. scibot 30 Apr 2021
      RRID:AB_10950970

      DOI: 10.1016/j.cmet.2020.10.021

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    sciencedirect.com/science/article/pii/S1550413120305544
  79. Feb 2021
  80. www.sciencedirect.com www.sciencedirect.com
    microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP
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    1. scibot 28 Feb 2021
      RRID:AB_10950970

      DOI: 10.1016/j.molcel.2021.01.030

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  81. www.sciencedirect.com www.sciencedirect.com
    Evasion of type-I interferon by SARS-CoV-2
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    1. scibot 26 Feb 2021
      RRID:AB_10950970

      DOI: 10.1016/j.celrep.2020.108234

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    sciencedirect.com/science/article/pii/S2211124720312237
  82. Oct 2020
  83. www.sciencedirect.com www.sciencedirect.com
    Evasion of type-I interferon by SARS-CoV-2
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    1. scibot 01 Oct 2020
      RRID:AB_10950970

      DOI: 10.1016/j.celrep.2020.108234

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  84. Sep 2020
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-inflammatory, antioxidant and renoprotective effects of SOCS1 mimetic peptide in the BTBR ob/ob mouse model of type 2 diabetes
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    1. scibot 23 Sep 2020
      RRID:AB_10950970

      DOI: 10.1136/bmjdrc-2020-001242

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  86. rupress.org rupress.org
    Glioma stem-like cells evade interferon suppression through MBD3/NuRD complex–mediated STAT1 downregulation
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    1. scibot 11 Sep 2020
      RRID:AB_10950970

      DOI: 10.1084/jem.20191340

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    rupress.org/jem/article/217/5/e20191340/151561/Glioma-stem-like-cells-evade-interferon
  87. www.sciencedirect.com www.sciencedirect.com
    Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
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    1. scibot 04 Sep 2020
      RRID:AB_10950970

      DOI: 10.1016/j.cell.2020.03.040

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    sciencedirect.com/science/article/pii/S0092867420303330
  88. Jan 2020
  89. www.sciencedirect.com www.sciencedirect.com
    Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses
    1
    1. scibot 13 Jan 2020
      RRID:AB_11220426

      DOI: 10.1016/j.immuni.2019.06.007

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    sciencedirect.com/science/article/pii/S1074761319302778
  90. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Activation of peroxisome proliferator‐activated receptor delta suppresses BACE1 expression by up‐regulating SOCS1 in a JAK2/STAT1‐dependent manner
    1
    1. scibot 13 Jan 2020
      RRID:AB_10950970

      DOI: 10.1111/jnc.14715

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14715
  91. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions
    1
    1. scibot 13 Jan 2020
      RRID:AB_10950970

      DOI: 10.1016/j.molcel.2019.07.034

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    sciencedirect.com/science/article/pii/S1097276519305891
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_10950970

      DOI: 10.7554/eLife.41159

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    ncbi.nlm.nih.gov/pmc/articles/PMC6389286/
  93. Nov 2018
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Efficacy of the Interferon Alpha/Beta Response versus Arboviruses Is Temperature Dependent
    1
    1. scibot 05 Nov 2018
      RRID:AB_10950970

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    ncbi.nlm.nih.gov/pmc/articles/PMC5915735/
  95. europepmc.org europepmc.org
    Untitled document
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      RRID:AB_10950970

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    europepmc.org/articles/PMC5915735/