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130 Matching Annotations

Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection

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1. scibot 19 Aug 2025
  
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  DOI: 10.1126/sciadv.adx6587
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12356262/
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Targeting lipid scrambling potentiates ferroptosis and triggers tumor immune rejection

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  DOI: 10.1126/sciadv.adx6587
  
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Cannabichromene: integrative modulation of apoptosis, ferroptosis, and endocannabinoid signaling in pancreatic cancer therapy

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1. scibot 14 Aug 2025
  
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  DOI: 10.1038/s41420-025-02674-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12340112/
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TRIM65 as a key regulator of ferroptosis and glycolysis in lactate-driven renal tubular injury and diabetic kidney disease

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1. scibot 01 Aug 2025
  
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Jul 2025
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SESN2 maintains cartilage homeostasis by SREBP1-mediated lipid metabolism during osteoarthritis progression

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1. scibot 29 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.113097
  
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Oxidative stress and Kras mutation in Mist1+ cells act in a double-hit manner to drive gastric tumorigenesis

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  DOI: 10.1016/j.celrep.2025.116014
  
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Jun 2025
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Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research

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  DOI: 10.4103/1673-5374.339491
  
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journals.lww.com/nrronline/fulltext/2026/04000/the_cullin3_ring_e3_ubiquitin_ligase_complex_and.44.aspx
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The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis

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  DOI: 10.1016/j.cell.2025.05.029
  
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sciencedirect.com/science/article/pii/S0092867425006166
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Engineered Extracellular Vesicle-Delivered CRISPR/Cas9 for Radiotherapy Sensitization of Glioblastoma

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  DOI: 10.1021/acsnano.2c12857
  
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pubs.acs.org/doi/full/10.1021/acsnano.2c12857
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Pannexin-1 Aggravates Inflammatory Bowel Disease via Unbalancing Macrophage Polarisation and Triggering Ferroptosis in Mice

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1. scibot 11 Jun 2025
  
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  DOI: 10.1111/imm.13948
  
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onlinelibrary.wiley.com/doi/10.1111/imm.13948
52.53.155.43 52.53.155.43

Inhibition of NAD-GPx4 axis and MEK triggers ferroptosis to suppress pancreatic ductal adenocarcinoma

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1. scibot 05 Jun 2025
  
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  DOI: 10.1016/j.ymthe.2025.05.037
  
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52.53.155.43/971823f8b21eb8d89d5a30c0b92ea104b80dbdce/PDF-html.html
May 2025
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Bromodomain-containing protein 4 knockdown promotes... : Neural Regeneration Research

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1. scibot 30 May 2025
  
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  DOI: 10.4103/NRR.NRR-D-24-00147
  
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journals.lww.com/nrronline/fulltext/2026/02000/bromodomain_containing_protein_4_knockdown.41.aspx
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Dysregulation of Labile Iron Predisposes Chemotherapy Resistant Cancer Cells to Ferroptosis

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1. scibot 21 May 2025
  
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  DOI: 10.3390/ijms26094193
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12072162/
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Mitochondrial CCN1 drives ferroptosis via fatty acid β-oxidation

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.devcel.2025.04.004
  
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sciencedirect.com/science/article/pii/S1534580725002060
Apr 2025
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Cytosolic cytochrome c represses ferroptosis

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.cmet.2025.03.014
  
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sciencedirect.com/science/article/pii/S1550413125001494
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Developmental Programming: Mechanisms of Early Exposure to Real-Life Chemicals in Biosolids on Offspring Ovarian Dynamics

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1. scibot 10 Apr 2025
  
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  DOI: 10.1093/biolre/ioaf053
  
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52.53.155.43/01affc2e74b31ccd26976fa83a1f0404cb1ac361/ioaf053-html.html
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1-s2.0-S2589004225006248-main-html.html

1
1. scibot 10 Apr 2025
  
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  DOI: 10.1016/j.isci.2025.112363
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12053632/
Mar 2025
www.cell.com www.cell.com

Realigned transsulfuration drives BRAF-V600E-targeted therapy resistance in melanoma

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1. scibot 07 Mar 2025
  
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  DOI: 10.1016/j.cmet.2025.01.021
  
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cell.com/cell-metabolism/fulltext/S1550-4131(25)00021-X
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Treadmill exercise in combination with acousto-optic and... : Neural Regeneration Research

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  DOI: 10.4103/NRR.NRR-D-23-01681
  
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journals.lww.com/nrronline/fulltext/2025/09000/treadmill_exercise_in_combination_with.31.aspx
Feb 2025
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Nrg4 Secreted by Brown Adipose Tissue Suppresses Ferroptosis of Sepsis-Induced Liver Injury

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1. scibot 20 Feb 2025
  
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  DOI: 10.1007/s10753-024-02230-z
  
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link.springer.com/article/10.1007/s10753-024-02230-z
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SaaS sRNA promotes the interfering effect of Salmonella on hepatic iron metabolism via modulating ferroportin 1

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  DOI: 10.1016/j.isci.2024.111660
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11810840/
Jan 2025
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Targeting pancreatic cancer glutamine dependency confers vulnerability to GPX4-dependent ferroptosis

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1. scibot 30 Jan 2025
  
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  DOI: 10.1016/j.xcrm.2025.101928
  
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Predictive and prognostic value of ACSL4 and GPX4 in patients with esophageal squamous cell carcinoma receiving post-operative radiotherapy

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1. scibot 24 Jan 2025
  
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  DOI: 10.21037/jtd-24-1193
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11740077/
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HMOX1-LDHB interaction promotes ferroptosis by inducing mitochondrial dysfunction in foamy macrophages during advanced atherosclerosis

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  DOI: 10.1016/j.devcel.2024.12.011
  
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sciencedirect.com/science/article/pii/S1534580724007330
Dec 2024
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Nuclear receptor 4A1 facilitates complete Freund’s adjuvant-induced inflammatory pain in rats by promoting ferroptosis in spinal glial cells

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  DOI: 10.1016/j.bbi.2024.12.152
  
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Iron regulatory protein 1 deficient mice exhibit hypospermatogenesis

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  DOI: 10.1016/j.jbc.2024.108067
  
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sciencedirect.com/science/article/pii/S0021925824025699
Nov 2024
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PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization

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1. scibot 21 Nov 2024
  
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  DOI: 10.1016/j.molcel.2024.10.028
  
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Microbiota-derived lysophosphatidylcholine alleviates Alzheimer’s disease pathology via suppressing ferroptosis

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  DOI: 10.1016/j.cmet.2024.10.006
  
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Melatonin protects against particulate matter-induced ovarian dysfunction by activating the Nrf2 signaling pathway to alleviate ferroptosis

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  DOI: 10.1016/j.lfs.2024.123200
  
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Glutamate Transport Proteins and Metabolic Enzymes are Poor Prognostic Factors in Invasive Lobular Carcinoma

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  DOI: 10.1101/2024.09.29.615681
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11507668/
Sep 2024
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Hydrogen sulfide-mediated persulfidation regulates homocysteine metabolism and enhances ferroptosis in non-small cell lung cancer

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1. scibot 26 Sep 2024
  
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  DOI: 10.1016/j.molcel.2024.08.035
  
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Aug 2024
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Design, synthesis and biological evaluation of N-salicyloyl tryptamine derivatives as multifunctional neuroprotectants for the treatment of ischemic stroke

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1. scibot 28 Aug 2024
  
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  DOI: 10.1016/j.ejmech.2024.116795
  
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sciencedirect.com/science/article/pii/S0223523424006767
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Decursin ameliorates neurotoxicity induced by glutamate through restraining ferroptosis by up-regulating FTH1 in SH-SY5Y neuroblastoma cells

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1. scibot 28 Aug 2024
  
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  DOI: 10.1016/j.neuroscience.2024.08.035
  
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CRISPR screening identifies PRMT1 as a key pro-ferroptotic gene via a two-layer regulatory mechanism

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1. scibot 23 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114662
  
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MMP9 drives ferroptosis by regulating GPX4 and iron signaling

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Spliceosomal GTPase Eftud2 deficiency-triggered ferroptosis leads to Purkinje cell degeneration

1
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OPA1 promotes ferroptosis by augmenting mitochondrial ROS and suppressing an integrated stress response

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Dopaminylation of endothelial TPI1 suppresses ferroptotic angiocrine signals to promote lung regeneration over fibrosis

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Bradykinin induces acute kidney injury after hypothermic circulatory arrest through repression of the Nrf2-xCT pathway

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BPS Publications

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Eupalinolide B suppresses pancreatic cancer by ROS generation and potential cuproptosis

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Ferroptosis induces nucleolar stress as revealed by live-cell imaging using thioflavin T

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The role of JMJD2A in immune evasion and malignant behavior of esophageal squamous cell carcinoma

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STING orchestrates the neuronal inflammatory stress response in multiple sclerosis

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HIF-1 induced tiRNA-Lys-CTT-003 is protective against cisplatin induced ferroptosis of renal tubular cells in mouse AKI model

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Bradykinin induces acute kidney injury after hypothermic circulatory arrest through repression of the Nrf2-xCT pathway

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USP7 upregulated by TGF-β1 promotes ferroptosis via inhibiting LATS1-YAP axis in sepsis-induced acute lung injury

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Targeting the Ferroptosis and Endoplasmic Reticulum Stress Signaling Pathways by CBX7 in Myocardial Ischemia/reperfusion Injury

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Fatal COVID-19 pulmonary disease involves ferroptosis

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  DOI: 10.1038/s41467-024-48055-0
  
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Metformin alleviates spinal cord injury by inhibiting nerve cell ferroptosis through upregulation of heme oxygenase-1 expression

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p38 MAPK inhibitor SB202190 suppresses ferroptosis in the glutamate-induced retinal excitotoxicity glaucoma model

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A mechanism linking p53-mediated ferroptosis and NCOA4-mediated ferritinophagy in melatonin-related improvement of diabetic brain injury

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Baicalein improves renal interstitial fibrosis by inhibiting the ferroptosis in vivo and in vitro

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Induction of stearoyl-CoA desaturase confers cell density-dependent ferroptosis resistance in melanoma

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Metaplastic regeneration in the mouse stomach requires a reactive oxygen species pathway

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A tangible method to assess native ferroptosis suppressor activity

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Osteoclast-Cancer Cell Metabolic Crosstalk Confers PARP Inhibitor Resistance in Bone Metastatic Breast Cancer

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Phospholipids with two polyunsaturated fatty acyl tails promote ferroptosis

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PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression

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Metformin alleviates hepatic iron overload and ferroptosis through AMPK-ferroportin pathway in HFD-induced NAFLD

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TXNDC12 inhibits lipid peroxidation and ferroptosis

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SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation

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Sbp2l contributes to oligodendrocyte maturation through translational control in Tcf7l2 signaling

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ABHD12 contributes to tumorigenesis and sorafenib resistance by preventing ferroptosis in hepatocellular carcinoma

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Fucoxanthin ameliorates traumatic brain injury by suppressing the blood brain barrier disruption

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Oct 2023
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bqad159-html.html

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  DOI: 10.1210/endocr/bqad159
  
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Glutathione dynamics is a potential predictive and therapeutic trait for neoadjuvant chemotherapy response in bladder cancer

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  DOI: 10.1016/j.xcrm.2023.101224
  
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AMER1 deficiency promotes the distant metastasis of colorectal cancer by inhibiting SLC7A11- and FTL-mediated ferroptosis

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MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis

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bvad117-html.html

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Mechanism of SOX10 in ferroptosis of hippocampal neurons after intracerebral hemorrhage via the miR-29a-3p/ACSL4 axis

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Mitoquinone alleviates osteoarthritis progress by activating the NRF2-Parkin axis

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Unraveling Vulnerabilities in Endocrine Therapy-Resistant HER2+/ER+ Breast Cancer

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Effectors Enabling Adaptation to Mitochondrial Complex I Loss in Hürthle Cell Carcinoma

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Ferroptosis inhibition protects vascular endothelial cells and maintains integrity of the blood-spinal cord barrier after spinal cord injury

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Marchf6 E3 ubiquitin ligase critically regulates endoplasmic reticulum stress, ferroptosis, and metabolic homeostasis in POMC neurons

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Immunometabolic coevolution defines unique microenvironmental niches in ccRCC

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Metronomic capecitabine inhibits liver transplant rejection in rats by triggering recipients’ T cell ferroptosis

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Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones

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Activation of Nrf2 signaling pathway by Tectoridin protects against ferroptosis in particulate matter-induced lung injury

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AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells

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C5a-licensed phagocytes drive sterilizing immunity during systemic fungal infection

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Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis

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BPS Publications

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KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells

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Upregulation of CDGSH iron sulfur domain 2 attenuates cerebral ischemia/reperfusion injury

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Prolonged maternal exposure to glucocorticoids alters selenoprotein expression in the developing brain

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Melatonin inhibits ferroptosis and delays age-related cataract by regulating SIRT6/p-Nrf2/GPX4 and SIRT6/NCOA4/FTH1 pathways

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m6A modification of circSPECC1 suppresses RPE oxidative damage and maintains retinal homeostasis

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Sex differences in resilience to ferroptosis underlie sexual dimorphism in kidney injury and repair

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Ferroptosis inhibition by lysosome-dependent catabolism of extracellular protein

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Selenium modulates cancer cell response to pharmacologic ascorbate

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Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy

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Single cell RNA-seq analysis identifies ferroptotic chondrocyte cluster and reveals TRPV1 as an anti-ferroptotic target in osteoarthritis

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Intrathecal liproxstatin-1 delivery inhibits ferroptosis... : Neural Regeneration Research

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Low ferroptosis score predicts chemotherapy responsiveness and immune-activation in colorectal cancer

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Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity

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DL-3-n-butylphthalide alleviates motor disturbance by... : Neural Regeneration Research

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Efficiently suppress of ferroptosis using deferoxamine nanoparticles as a new method for retinal ganglion cell protection after traumatic optic neuropathy

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BPS Publications

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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15834
Mar 2022
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Selenoprotein P-mediated reductive stress impairs cold-induced thermogenesis in brown fat

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  DOI: 10.1016/j.celrep.2022.110566
  
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sciencedirect.com/science/article/pii/S2211124722003102
Feb 2022
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Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression

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  DOI: 10.1016/j.ebiom.2022.103847
  
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  DOI: 10.1016/j.ebiom.2022.103847
  
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sciencedirect.com/science/article/pii/S2352396422000317
Sep 2021
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Predictive and prognostic impact of ferroptosis-related genes ACSL4 and GPX4 on breast cancer treated with neoadjuvant chemotherapy

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  DOI: 10.1016/j.ebiom.2021.103560
  
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sciencedirect.com/science/article/pii/S2352396421003534
Aug 2021
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Newcastle-disease-virus-induced ferroptosis through nutrient deprivation and ferritinophagy in tumor cells

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  DOI: 10.1016/j.isci.2021.102837
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8326413/
chemistry-europe.onlinelibrary.wiley.com chemistry-europe.onlinelibrary.wiley.com

Forward chemical genetic screen for oxygen-dependent cytotoxins uncovers new covalent fragments that target GPX4

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  ab125066
  
  DOI: 10.1002/cbic.202100253
  
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chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cbic.202100253
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Ferroptotic stress promotes the accumulation of pro-inflammatory proximal tubular cells in maladaptive renal repair

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1. scibot 06 Aug 2021
  
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  DOI: 10.7554/eLife.68603
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8318592/
Jul 2021
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Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

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1. scibot 31 Jul 2021
  
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  DOI: 10.1016/j.cmet.2019.01.020
  
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Untitled document

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1. scibot 30 Jul 2021
  
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  DOI: 10.1111/jnc.14604
  
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onlinelibrary.wiley.com/doi/full/10.1111/jnc.14604
Jun 2021
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The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity

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1. scibot 16 Jun 2021
  
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  DOI: 10.1016/j.celrep.2021.109235
  
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sciencedirect.com/science/article/pii/S2211124721005945
May 2021
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3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis

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1. scibot 07 May 2021
  
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  DOI: 10.1016/j.molcel.2020.10.010
  
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sciencedirect.com/science/article/pii/S1097276520306936
Apr 2021
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Inhibition of Acyl-CoA Synthetase Long-Chain Family Member 4 Facilitates Neurological Recovery After Stroke by Regulation Ferroptosis

1
1. scibot 17 Apr 2021
  
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  DOI: 10.3389/fncel.2021.632354
  
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frontiersin.org/article/10.3389/fncel.2021.632354/full
Mar 2021
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MGST1 is a redox-sensitive repressor of ferroptosis in pancreatic cancer cells

1
1. scibot 22 Mar 2021
  
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  AB_10973901
  
  DOI: 10.1016/j.chembiol.2021.01.006
  
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sciencedirect.com/science/article/pii/S2451945621000064
Feb 2021
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Polyamine pathway activity promotes cysteine essentiality in cancer cells

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1. scibot 26 Feb 2021
  
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  GPX4
  
  DOI: 10.1038/s42255-020-0253-2
  
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Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1

1
1. scibot 25 Feb 2021
  
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  RRID:AB_10973901
  
  DOI: 10.1016/j.molcel.2020.11.024
  
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cell.com/molecular-cell/fulltext/S1097-2765(20)30802-9
Dec 2020
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HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications

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1. scibot 13 Dec 2020
  
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  RRID:AB_10973901
  
  DOI: 10.1016/j.celrep.2020.108487
  
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sciencedirect.com/science/article/pii/S2211124720314765
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Comparative Proteomics Unveils LRRFIP1 as a New Player in the DAPK1 Interactome of Neurons Exposed to Oxygen and Glucose Deprivation

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1. scibot 07 Dec 2020
  
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  RRID:AB_10973901
  
  DOI: 10.3390/antiox9121202
  
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mdpi.com/2076-3921/9/12/1202
Jan 2020
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A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering

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1. scibot 13 Jan 2020
  
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  RRID:AB_10973901
  
  DOI: 10.1016/j.cell.2019.10.032
  
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sciencedirect.com/science/article/pii/S0092867419311821
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The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.07.107
  
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sciencedirect.com/science/article/pii/S221112471931023X
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Neuroprotective effects of Brazilian green propolis on oxytosis/ferroptosis in mouse hippocampal HT22 cells

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1. scibot 13 Jan 2020
  
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  RRID:AB_10973901
  
  DOI: 10.1016/j.fct.2019.110669
  
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Untitled document

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  DOI: 10.1016/j.chembiol.2018.11.016
  
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Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion

1
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  RRID:AB_10973901
  
  DOI: 10.1016/j.cmet.2019.01.020
  
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sciencedirect.com/science/article/pii/S1550413119300208
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency

1
1. scibot 05 Nov 2018
  
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AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0960982218307644
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Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency

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1. scibot 05 Nov 2018
  
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Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis

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sciencedirect.com/science/article/pii/S1931312818302634
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Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0092867417314381

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