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133 Matching Annotations

Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Age-dependent topoisomerase I depletion alters recruitment of rDNA silencing complexes

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1. scibot 12 Aug 2025
  
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  DOI: 10.1101/2025.07.29.667507
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12324367/
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Principles of cotranslational mitochondrial protein import

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1. scibot 12 Aug 2025
  
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  DOI: 10.1016/j.cell.2025.07.021
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12396113/
52.53.155.43 52.53.155.43

1-s2.0-S2589004225015640-main-html.html

1
1. scibot 07 Aug 2025
  
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  DOI: 10.1016/j.isci.2025.113303
  
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52.53.155.43/bac317aedc80aa24da9dcbcc0da4fd2f5d6915e9/1-s2.0-S2589004225015640-main-html.html
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Evidence for human kisspeptin receptor homo-oligomerisation and its functional relevance

1
1. scibot 06 Aug 2025
  
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  DOI: 10.1530/JME-25-0043
  
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sciencedirect.com/org/science/article/pii/S1479681325000172
Jul 2025
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A mechanistic basis of fast myofiber vulnerability to neuromuscular diseases

1
1. scibot 09 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.115959
  
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sciencedirect.com/science/article/pii/S2211124725007302
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PARP1-NFATc1-PD1 pathway of maturation and stability of CD8+T cells is beneficial against chronic Trypanosoma cruzi infection

1
1. scibot 08 Jul 2025
  
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  DOI: 10.1016/j.isci.2025.112926
  
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sciencedirect.com/science/article/pii/S2589004225011873
Jun 2025
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Distinct cAMP Regulation in Scleroderma Lung and Skin Myofibroblasts Governs Their Dedifferentiation via p38α Inhibition

1
1. scibot 26 Jun 2025
  
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  DOI: 10.1096/fj.202500694RR
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12186599/
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Cell autonomous microglia defects in a stem cell model of frontotemporal dementia tau

1
1. scibot 18 Jun 2025
  
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  DOI: 10.1038/s41380-025-03073-2
  
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link.springer.com/article/10.1038/s41380-025-03073-2
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Conformational dynamics of a histidine molecular switch in a cation/proton antiporter

1
1. scibot 18 Jun 2025
  
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  DOI: 10.1016/j.bbabio.2025.149563
  
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sciencedirect.com/science/article/pii/S0005272825000295
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PDF-html.html

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1. scibot 17 Jun 2025
  
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  DOI: 10.1158/2159-8290.cd-24-1904
  
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52.53.155.43/fedd6ccff8c0b6494dbe8595a0c800e33e0860f7/PDF-html.html
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Differential Effects of Canonical Androgens and 11-Ketotestosterone on Reproductive Phenotypes and Folliculogenesis in Mouse Model of PCOS

1
1. scibot 12 Jun 2025
  
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  RRID:AB_10977387
  
  DOI: 10.3390/biomedicines13051077
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12109480/
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Muscle metabolic resilience and enhanced exercise adaptation by Esr1-induced remodeling of mitochondrial cristae-nucleoid architecture in males

1
1. scibot 11 Jun 2025
  
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  RRID:AB_10977387
  
  DOI: 10.1016/j.xcrm.2025.102116
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12147913/
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The cell-surface shared proteome of astrocytes and neurons and the molecular foundations of their multicellular interactions

1
1. scibot 11 Jun 2025
  
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  RRID:AB_10977387
  
  DOI: 10.1016/j.neuron.2025.05.019
  
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sciencedirect.com/science/article/pii/S0896627325003666
52.53.155.43 52.53.155.43

1-s2.0-S2589004225010934-main-html.html

1
1. scibot 11 Jun 2025
  
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  RRID:AB_10977387
  
  DOI: 10.1016/j.isci.2025.112832
  
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52.53.155.43/0f2fd8c15b0c5cf23f5185a8e61e308e4038793f/1-s2.0-S2589004225010934-main-html.html
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PIN1 serves as a prognostic and therapeutic biomarker in lung adenocarcinoma

1
1. scibot 11 Jun 2025
  
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  RRID:AB_10977387
  
  DOI: 10.1007/s10142-025-01629-7
  
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link.springer.com/article/10.1007/s10142-025-01629-7
Mar 2025
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siRNA-AGO2 complex inhibits bacterial gene translation: A promising therapeutic strategy for superbug infection

1
1. scibot 07 Mar 2025
  
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  RRID:AB_10977387
  
  DOI: 10.1016/j.xcrm.2025.101997
  
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sciencedirect.com/science/article/pii/S2666379125000709
Jan 2025
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Phospho-regulation of ASCL1-mediated chromatin opening during cellular reprogramming

1
1. scibot 24 Jan 2025
  
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  RRID:AB_10977387
  
  DOI: 10.1242/dev.204329
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11664170/
52.53.155.43 52.53.155.43

can-23-2194-html.html

1
1. scibot 04 Jan 2025
  
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  RRID:AB_10977387
  
  DOI: 10.1158/0008-5472.can-23-2194
  
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52.53.155.43/bd8889ff5443fd583f7250d78b553c7707371669/PDF-html.html
Dec 2024
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 29 Dec 2024
  
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  RRID:AB_10977387
  
  DOI: 10.1101/2024.12.20.629634
  
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52.53.155.43/8a7c3f6b8aff86a064d8132c6cfc5572d2ac9598/PDF-html.html
52.53.155.43 52.53.155.43

can-23-2194-html.html

1
1. scibot 24 Dec 2024
  
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  RRID:AB_10977387
  
  DOI: 10.1158/0008-5472.can-23-2194
  
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52.53.155.43/bd8889ff5443fd583f7250d78b553c7707371669/PDF-html.html
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Interleukin-1α release during necrotic-like cell death generates myeloid-driven immunosuppression that restricts anti-tumor immunity

1
1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.ccell.2024.10.014
  
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sciencedirect.com/science/article/pii/S1535610824004021
Nov 2024
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Sleep deprivation leads to non-adaptive alterations in sleep microarchitecture and amyloid-β accumulation in a murine Alzheimer model

1
1. scibot 20 Nov 2024
  
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  DOI: 10.1016/j.celrep.2024.114977
  
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sciencedirect.com/science/article/pii/S2211124724013287
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CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity

1
1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.stem.2024.10.007
  
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sciencedirect.com/science/article/pii/S1934590924003692
Oct 2024
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The TMEM132B-GABAA receptor complex controls alcohol actions in the brain

2
1. scibot 02 Oct 2024
  
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  DOI: 10.1016/j.cell.2024.09.006
  
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2. scibot 02 Oct 2024
  
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  AB_10977387
  
  DOI: 10.1016/j.cell.2024.09.006
  
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sciencedirect.com/science/article/pii/S0092867424010249
Sep 2024
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mCAUSE: Prioritizing Mitochondrial Targets that Alleviate Pancreatic Cancer Cell Phenotypes

1
1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.isci.2024.110880
  
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sciencedirect.com/science/article/pii/S2589004224021059
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Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes

1
1. scibot 25 Sep 2024
  
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  RRID:AB_2537659
  
  DOI: 10.1016/j.celrep.2020.107925
  
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sciencedirect.com/science/article/pii/S2211124720309062
Aug 2024
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Mechanism of homology search expansion during recombinational DNA break repair in Saccharomyces cerevisiae

1
1. scibot 23 Aug 2024
  
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  DOI: 10.1016/j.molcel.2024.08.003
  
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sciencedirect.com/science/article/pii/S1097276524006579
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Viral hijacking of hnRNPH1 unveils a G-quadruplex-driven mechanism of stress control

1
1. scibot 18 Aug 2024
  
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  DOI: 10.1016/j.chom.2024.07.006
  
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sciencedirect.com/science/article/pii/S1931312824002658
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions

1
1. scibot 30 Jul 2024
  
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  DOI: 10.1016/j.neuron.2024.06.002
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11377155/
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An ankyrin G–binding motif mediates TRAAK periodic localization at axon initial segments of hippocampal pyramidal neurons

1
1. scibot 30 Jul 2024
  
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  RRID:AB_10977387
  
  DOI: 10.1073/pnas.2310120121
  
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pnas.org/doi/abs/10.1073/pnas.2310120121
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Zinc Finger RNA-Binding Protein Zn72D Regulates ADAR-Mediated RNA Editing in Neurons

1
1. scibot 20 Jul 2024
  
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  DOI: 10.1016/j.celrep.2020.107654
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7306179/
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Genome-wide quantification of RNA flow across subcellular compartments reveals determinants of the mammalian transcript life cycle

1
1. scibot 16 Jul 2024
  
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  RRID:AB_10977387
  
  DOI: 10.1016/j.molcel.2024.06.008
  
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cell.com/molecular-cell/fulltext/S1097-2765(24)00511-2
Jun 2024
www.cell.com www.cell.com

Human gut Actinobacteria boost drug absorption by secreting P-glycoprotein ATPase inhibitors

1
1. scibot 30 Jun 2024
  
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  RRID:AB_10977387
  
  DOI: 10.1016/j.isci.2024.110122
  
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cell.com/iscience/abstract/S2589-0042(24)01347-6
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CGG repeats in the human FMR1 gene regulate mRNA localization and cellular stress in developing neurons

1
1. scibot 21 Jun 2024
  
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  RRID:AB_10977387
  
  DOI: 10.1016/j.celrep.2024.114330
  
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Cell autonomous microglia defects in a stem cell model of frontotemporal dementia

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May 2024
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Systemic Phospho-Defective and Phospho-Mimetic Drp1 Mice Exhibit Normal Growth and Development with Altered Anxiety-like Behavior

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Apr 2024
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Numb positively regulates Hedgehog signaling at the ciliary pocket

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  DOI: 10.1038/s41467-024-47244-1
  
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Feb 2024
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Targeted delivery of immune-stimulating bispecific RNA, inducing apoptosis and anti-tumor immunity in cancer cells

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  DOI: 10.1016/j.isci.2024.109068
  
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Gut-Brain Axis Interplay via STAT3 pathway: Implications of Helicobacter pylori derived secretome on inflammation and Alzheimer's disease

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  DOI: 10.1080/21505594.2024.2303853
  
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LDO proteins and Vac8 form a vacuole-lipid droplet contact site to enable starvation-induced lipophagy in yeast

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  DOI: 10.1016/j.devcel.2024.01.014
  
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Single-molecule imaging of stochastic interactions that drive dynein activation and cargo movement in cells

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TALK-1-mediated alterations of β-cell mitochondrial function and insulin secretion impair glucose homeostasis on a diabetogenic diet

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Metabolomic analysis of a selective ABCA1 inducer in obesogenic challenge provides a rationale for therapeutic development

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  DOI: 10.1016/j.ebiom.2021.103287
  
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Erythroid Differentiation Dependent Interaction of VPS13A with XK at the Plasma Membrane of K562 Cells

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  DOI: 10.1177/25152564231215133
  
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Structures and roles of BcsD and partner scaffold proteins in proteobacterial cellulose secretion

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Ovarian ERβ cistrome and transcriptome reveal chromatin interaction with LRH-1

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Relevance of augmented kisspeptin signaling through H364 KISS1R in central precocious puberty

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Nov 2023
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Single-molecule quantitation of RNA-binding protein occupancy and stoichiometry defines a role for Yra1 (Aly/REF) in nuclear mRNP organization

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Oct 2023
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GLUT-1 changes in paediatric Huntington disease brain cortex and fibroblasts: an observational case-control study

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Long non-coding RNA SNHG8 drives stress granule formation in tauopathies

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  DOI: 10.1038/s41380-023-02237-2
  
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Aug 2023
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Metformin rescues migratory deficits of cells derived from patients with periventricular heterotopia

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  DOI: 10.15252/emmm.202216908
  
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Erythroid differentiation dependent interaction of VPS13A with XK at the plasma membrane of K562 cells

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  DOI: 10.1101/2023.08.09.552634
  
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Chaperone-mediated autophagy in neuronal dendrites utilizes activity-dependent lysosomal exocytosis for protein disposal

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  DOI: 10.1016/j.celrep.2023.112998
  
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A dynamic actin cytoskeleton is required to prevent constitutive VDAC-dependent MAPK signalling and aberrant lipid homeostasis

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  DOI: 10.1016/j.isci.2023.107539
  
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Jul 2023
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Super-resolution imaging unveils the self-replication of tau aggregates upon seeding

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Jun 2023
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Ectopically Expressed Meiosis-Specific Cancer Testis Antigen HORMAD1 Promotes Genomic Instability in Squamous Cell Carcinomas

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  DOI: 10.3390/cells12121627
  
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May 2023
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Investigating the NRAS 5′ UTR as a target for small molecules

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The RhoA-ROCK1/ROCK2 Pathway Exacerbates Inflammatory Signaling in Immortalized and Primary Microglia

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Apr 2023
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Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation

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  DOI: 10.1007/s00401-023-02568-y
  
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Mar 2023
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PQBP1 regulates striatum development through balancing striatal progenitor proliferation and differentiation

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  DOI: 10.1016/j.celrep.2023.112277
  
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Smad4-mediated angiogenesis facilitates the beiging of white adipose tissue in mice

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  DOI: 10.1016/j.isci.2023.106272
  
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Feb 2023
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Role of human HSPE1 for OPA1 processing independent of HSPD1

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Bradykinin 2 Receptors Contribute to the Exaggerated Exercise Pressor Reflex in a Rat Model of Simulated Peripheral Artery Disease

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  DOI: 10.1152/ajpregu.00274.2022
  
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Jan 2023
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Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation

1
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Nov 2022
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Chronic Trazodone and Citalopram Treatments Increase Trophic Factor and Circadian Rhythm Gene Expression in Rat Brain Regions Relevant for Antidepressant Efficacy

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Sep 2022
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Insulin and serine metabolism as sex-specific hallmarks of Alzheimer’s disease in the human hippocampus

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  DOI: 10.1016/j.celrep.2022.111271
  
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Loss of oligodendrocyte ErbB receptor signaling leads to hypomyelination, reduced density of parvalbumin-expressing interneurons, and inhibitory function in the auditory cortex

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  DOI: 10.1002/glia.24266
  
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Aug 2022
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Pressure and curvature control of the cell cycle in epithelia growing under spherical confinement

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  DOI: 10.1016/j.celrep.2022.111227
  
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Increasing cell size remodels the proteome and promotes senescence

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  DOI: 10.1016/j.molcel.2022.07.017
  
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Robust anti-SARS-CoV2 single domain antibodies cross neutralize multiple viruses

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The Parkinson’s disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability

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  DOI: 10.1016/j.cell.2022.05.008
  
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Cholesterol determines the cytosolic entry and seeded aggregation of tau

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SRSF3-mediated regulation of N6-methyladenosine modification-related lncRNA ANRIL splicing promotes resistance of pancreatic cancer to gemcitabine

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Apr 2022
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Novel mechanosensory role for acid sensing ion channel subtype 1a in evoking the exercise pressor reflex in rats with heart failure

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Loss of CDKL5 in glutamatergic neurons disrupts hippocampal microcircuitry and leads to memory impairment in mice

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Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation

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  DOI: 10.1038/s41418-022-00983-4
  
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Loss of Claudin-4 Reduces DNA Damage Repair and Increases Sensitivity to PARP Inhibitors

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Mar 2022
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A selective PPM1A inhibitor activates autophagy to restrict the survival of Mycobacterium tuberculosis

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Prevention and Regression of Megamitochondria and Steatosis by Blocking Mitochondrial Fusion in the Liver

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Feb 2022
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Autophagy and intracellular product degradation genes identified by systems biology analysis reduce aggregation of bispecific antibody in CHO cells

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CXCL4 drives fibrosis by promoting several key cellular and molecular processes

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A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis

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Robust Expression of Functional NMDA Receptors in Human Induced Pluripotent Stem Cell-Derived Neuronal Cultures Using an Accelerated Protocol

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Experiments from unfinished Registered Reports in the Reproducibility Project: Cancer Biology

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  DOI: 10.7554/eLife.73430
  
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TAOK2 is an ER-localized kinase that catalyzes the dynamic tethering of ER to microtubules

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  DOI: 10.1016/j.devcel.2021.11.015
  
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Multisite phosphorylation by Cdk1 initiates delayed negative feedback to control mitotic transcription

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USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma

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Adrenal Corticosteroid Perturbation by the Endocrine Disruptor BDE-47 in a Human Adrenocortical Cell Line and Male Rats

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Thromboxane A2 receptors contribute to the exaggerated exercise pressor reflex in male rats with heart failure

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KARATE: PKA-induced KRAS4B-RHOA-mTORC2 supercomplex phosphorylates AKT in insulin signaling and glucose homeostasis

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Development of mammalian cell logic gates controlled by unnatural amino acids

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Stimulus evoked ERK-dependent phosphorylation of activity-regulated cytoskeleton-associated protein (Arc) regulates its neuronal subcellular localization

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Methylation of dual-specificity phosphatase 4 controls cell differentiation

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Jul 2021
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Loss of the ribosomal RNA methyltransferase NSUN5 impairs global protein synthesis and normal growth

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A Conserved Cytoskeletal Signaling Cascade Mediates Neurotoxicity of FTDP-17 Tau Mutations In Vivo

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PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism

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  DOI: 10.1016/j.stem.2019.08.017
  
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Jun 2021
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Inhibition of the mTOR pathway and reprogramming of protein synthesis by MDM4 reduce ovarian cancer metastatic properties

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May 2021
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The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding

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The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake

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Cochlear supporting cells require GAS2 for cytoskeletal architecture and hearing

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  DOI: 10.1016/j.devcel.2021.04.017
  
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PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation

1
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  DOI: 10.1016/j.molcel.2021.01.032
  
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Drp1 Tubulates the ER in a GTPase-Independent Manner

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Genome‐Wide Estrogen Receptor β Chromatin Binding in Human Colon Cancer Cells Reveals its Tumor Suppressor Activity

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  DOI: 10.1002/ijc.33573
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33573
Apr 2021
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Cell Lineage-Based Stratification for Glioblastoma

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  DOI: 10.1016/j.ccell.2020.06.003
  
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Ogt controls neural stem/progenitor cell pool and adult neurogenesis through modulating Notch signaling

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Metabolomic analysis of a selective ABCA1 inducer in obesogenic challenge provides a rationale for therapeutic development

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  DOI: 10.1016/j.ebiom.2021.103287
  
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HspB5/αB‐crystallin phosphorylation at S45 and S59 is essential for protection of the dendritic tree of rat hippocampal neurons

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Development of a potent and selective chemical probe for the pleiotropic kinase CK2

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Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling

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No effect of endoperoxide 4 or thromboxane A2 receptor blockade on static mechanoreflex activation in rats with heart failure

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  RRID:AB_10977387
  
  DOI: 10.1113/EP088835
  
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The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo

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  DOI: 10.7554/eLife.56006
  
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Oncogenic Signaling Alters Cell Shape and Mechanics to Facilitate Cell Division under Confinement

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  DOI: 10.1016/j.devcel.2020.01.004
  
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A Dimeric Structural Scaffold for PRC2-PCL Targeting to CpG Island Chromatin

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  DOI: 10.1016/j.molcel.2019.12.019
  
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Fibroblast-Derived STC-1 Modulates Tumor-Associated Macrophages and Lung Adenocarcinoma Development

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  DOI: 10.1016/j.celrep.2020.107802
  
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Crosstalk between Lys63- and Lys11-polyubiquitin signaling at DNA damage sites is driven by Cezanne

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  GAPDH
  
  DOI: 10.1101/gad.332395.119
  
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Zinc Finger RNA-Binding Protein Zn72D Regulates ADAR-Mediated RNA Editing in Neurons

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  DOI: 10.1016/j.celrep.2020.107654
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7306179/
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The E3 Ubiquitin Ligase Mind Bomb 1 Controls Adenovirus Genome Release at the Nuclear Pore Complex

1
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  DOI: 10.1016/j.celrep.2019.11.064
  
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PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism

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  RRID:AB_10977387
  
  DOI: 10.1016/j.stem.2019.08.017
  
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A Simple DMSO-Based Method for Cryopreservation of Primary Hippocampal and Cortical Neurons

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  AB_10977387
  
  DOI: 10.1016/j.jneumeth.2019.108578
  
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Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase

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  RRID:AB_10977387
  
  DOI: 10.1016/j.str.2019.06.005
  
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Altered NMDAR signaling underlies autistic-like features in mouse models of CDKL5 deficiency disorder

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  RRID:AB_10977387
  
  DOI: 10.1038/s41467-019-10689-w
  
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Untitled document

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  DOI: 10.1016/j.molcel.2019.04.010
  
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Dynamic Processing of Displacement Loops during Recombinational DNA Repair

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  DOI: 10.1016/j.molcel.2019.01.005
  
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Untitled document

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  RRID:AB_10977387
  
  DOI: 10.1016/j.molcel.2019.02.017
  
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sciencedirect.com/science/article/pii/S1097276519301078
Nov 2018
onlinelibrary.wiley.com onlinelibrary.wiley.com

Untitled document

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onlinelibrary.wiley.com/doi/full/10.1111/jnc.14448
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Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease

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Centella asiatica increases hippocampal synaptic density and improves memory and executive function in aged mice

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onlinelibrary.wiley.com/doi/full/10.1002/brb3.1024
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Inhibition of Bacterial Gene Transcription with an RpoN-Based Stapled Peptide

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pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1

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pubmed.ncbi.nlm.nih.gov/29804836/
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A Conserved Cytoskeletal Signaling Cascade Mediates Neurotoxicity of FTDP-17 Tau Mutations In Vivo

1
1. scibot 05 Nov 2018
  
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  Curator: @Zeljana_Babic
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5761430/
Nov 2017
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Untitled document

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1. scibot 08 Nov 2017
  
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  Curator: @patriciaelyse_
  
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jneurosci.org/content/37/31/7420
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Stimulus evoked ERK-dependent phosphorylation of activity-regulated cytoskeleton-associated protein (Arc) regulates its neuronal subcellular localization

1
1. scibot 08 Nov 2017
  
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  mouse anti-GAPDH (Thermo Scientific MA5-15738; Antibody Registry: AB_10977387
  
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sciencedirect.com/science/article/pii/S0306452217304967

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