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Polo kinase inhibits protein phosphatase 1 to promote the spindle assembly checkpoint and prevent aneuploidy

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1. scibot 23 Oct 2025
  
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  DOI: 10.1016/j.cub.2025.09.049
  
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sciencedirect.com/science/article/pii/S0960982225012497
Oct 2025
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Local delivery of IL-15 and anti-PD-L1 nanobody by in vitro-transcribed circILNb elicits superior antitumor immunity in cold tumors

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1. scibot 11 Oct 2025
  
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  DOI: 10.1016/j.xcrm.2025.102413
  
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sciencedirect.com/science/article/pii/S2666379125004860
Sep 2025
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An isoform-specific RUNX1C–BTG2 axis governs AML quiescence and chemoresistance.

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1. scibot 07 Sep 2025
  
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  DOI: 10.1158/2643-3230.BCD-24-0327
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12405853/
Aug 2025
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RNA Pol II inhibition activates cell death independently from the loss of transcription

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1. scibot 19 Aug 2025
  
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  DOI: 10.1016/j.cell.2025.07.034
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12406974/
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Evidence for human kisspeptin receptor homo-oligomerisation and its functional relevance

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  DOI: 10.1530/JME-25-0043
  
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sciencedirect.com/org/science/article/pii/S1479681325000172
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AI-generated MLH1 small binder improves prime editing efficiency

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  DOI: 10.1016/j.cell.2025.07.010
  
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sciencedirect.com/science/article/pii/S0092867425007998
Jul 2025
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PELP1 coordinates the modular assembly and enzymatic activity of the rixosome complex

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1. scibot 30 Jul 2025
  
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  DOI: 10.1126/sciadv.adw4603
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12292926/
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Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice

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1. scibot 30 Jul 2025
  
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  DOI: 10.1101/2025.07.23.666448
  
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biorxiv.org/content/10.1101/2025.07.23.666448v1
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PELP1 coordinates the modular assembly and enzymatic activity of the rixosome complex

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1. scibot 29 Jul 2025
  
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  DOI: 10.1126/sciadv.adw4603
  
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science.org/doi/10.1126/sciadv.adw4603
Apr 2025
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The E3 ubiquitin ligase MGRN1 targets melanocortin receptors MC1R and MC4R via interactions with transmembrane adapters

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1. scibot 03 Apr 2025
  
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  DOI: 10.1101/2025.03.25.645338
  
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biorxiv.org/content/10.1101/2025.03.25.645338v1
Feb 2025
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BPS Publications

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1. scibot 20 Feb 2025
  
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  DOI: 10.1111/bph.17463
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17463
Jan 2025
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DDX50 cooperates with STAU1 to effect stabilization of pro-differentiation RNAs

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1. scibot 09 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115174
  
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sciencedirect.com/science/article/pii/S2211124724015250
Sep 2024
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Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/Stat3 attenuation

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1. scibot 18 Sep 2024
  
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  DOI: 10.1038/s41523-024-00687-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11401886/
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A nature-inspired HIF stabilizer derived from a highland-adaptation insertion of plateau pika Epas1 protein

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1. scibot 13 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114727
  
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sciencedirect.com/science/article/pii/S2211124724010787
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Streamlined regulation of chloroplast development in the liverwort Marchantia polymorpha

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1. scibot 06 Sep 2024
  
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  DOI: 10.1016/j.celrep.2024.114696
  
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sciencedirect.com/science/article/pii/S2211124724010477
Aug 2024
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The Ubiquitin Ligase Adaptor NDFIP1 Interacts with TRESK and Negatively Regulates the Background K+ Current

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1. scibot 30 Aug 2024
  
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  DOI: 10.3390/ijms25168879
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11355008/
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Disruption of nuclear speckle integrity dysregulates RNA splicing in C9ORF72-FTD/ALS

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1. scibot 27 Aug 2024
  
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  DOI: 10.1016/j.neuron.2024.07.025
  
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sciencedirect.com/science/article/pii/S0896627324005701
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Rpsa Signaling Regulates Cortical Neuronal Morphogenesis via Its Ligand, PEDF, and Plasma Membrane Interaction Partner, Itga6

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1. scibot 02 Aug 2024
  
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  DOI: 10.1093/cercor/bhab242
  
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academic.oup.com/cercor/advance-article-abstract/doi/10.1093/cercor/bhab242/6338536
Jul 2024
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Hfq mediates transcriptome-wide RNA structurome reprogramming under virulence-inducing conditions in a phytopathogen

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1. scibot 30 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114544
  
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cell.com/cell-reports/abstract/S2211-1247(24)00873-8
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1-s2.0-S2589004224017851-main-html.html

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1. scibot 25 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110560
  
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52.53.155.43/28f1f0cd51770599356cfb72d036c0e468b38b34/1-s2.0-S2589004224017851-main-html.html
Jun 2024
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Dzip1 is dynamically expressed in the vertebrate germline and regulates the development of Xenopus primordial germ cells

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.ydbio.2024.06.003
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11934228/
May 2024
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CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia

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1. scibot 16 May 2024
  
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  DOI: 10.1016/j.xcrm.2024.101572
  
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sciencedirect.com/science/article/pii/S2666379124002647
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A dynamin superfamily-like pseudoenzyme coordinates with MICOS to promote cristae architecture

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1. scibot 01 May 2024
  
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  DOI: 10.1016/j.cub.2024.04.028
  
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Apr 2024
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Enhancer switching in cell lineage priming is linked to eRNA, Brg1’s AT-hook, and SWI/SNF recruitment

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1. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.molcel.2024.03.013
  
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sciencedirect.com/science/article/pii/S1097276524002235
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Human V-ATPase function is positively and negatively regulated by TLDc proteins

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1. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.str.2024.03.009
  
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2. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.str.2024.03.009
  
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sciencedirect.com/science/article/pii/S0969212624000911
Jan 2024
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Identifying Transmembrane Interactions in Receptor Protein Tyrosine Phosphatase Homodimerization and Heterodimerization

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1. scibot 11 Jan 2024
  
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  DOI: 10.1007/978-1-0716-3569-8_13
  
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link.springer.com/protocol/10.1007/978-1-0716-3569-8_13
Dec 2023
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Synonymous codon usage regulates translation initiation

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  DOI: 10.1016/j.celrep.2023.113413
  
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Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase

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1. scibot 15 Dec 2023
  
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  DOI: 10.7554/eLife.87098
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10708890/
Nov 2023
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Macrophage autophagy deficiency-induced CEBPB accumulation alleviates atopic dermatitis via impairing M2 polarization

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.celrep.2023.113430
  
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RBFOX2 regulated EYA3 isoforms partner with SIX4 or ZBTB1 to control transcription during myogenesis

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1. scibot 04 Nov 2023
  
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  DOI: 10.1016/j.isci.2023.108258
  
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52.53.155.43/45fd8e5f649eeab4d04cc2e63a0e9be19b005cef/1-s2.0-S2589004223023350-main-html.html
Oct 2023
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SorCS2 binds progranulin to regulate motor neuron development

1
1. scibot 28 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113333
  
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An evolutionarily nascent architecture underlying the formation and emergence of biomolecular condensates

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1. scibot 06 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.112955
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10529244/
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High-volume hybridoma sequencing on the NeuroMabSeq platform enables efficient generation of recombinant monoclonal antibodies and scFvs for neuroscience research

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1. scibot 05 Oct 2023
  
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  DOI: 10.1038/s41598-023-43233-4
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10533561/
Sep 2023
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Promoting the activity of a receptor tyrosine phosphatase with a novel pH‐responsive transmembrane agonist inhibits cancer‐associated phenotypes

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1. scibot 02 Sep 2023
  
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  DOI: 10.1002/pro.4742
  
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NeuroMabSeq: high volume acquisition, processing, and curation of hybridoma sequences and their use in generating recombinant monoclonal antibodies and scFvs for neuroscience research

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  DOI: 10.1101/2023.06.28.546392
  
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A Proximity Labeling Strategy Enables Proteomic Analysis of Inter-organelle Membrane Contacts

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May 2023
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FEBS Press

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Dissecting the effects of GTPase and kinase domain mutations on LRRK2 endosomal localization and activity

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Mar 2023
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LIN28 and histone H3K4 methylase induce TLR4 to generate tumor-initiating stem-like cells

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Recruitment of Polo-like kinase couples synapsis to meiotic progression via inactivation of CHK-2

1
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All-optical physiology resolves a synaptic basis for behavioral timescale plasticity

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Glucose dissociates DDX21 dimers to regulate mRNA splicing and tissue differentiation

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Global profiling identifies a stress-responsive tyrosine site on EDC3 regulating biomolecular condensate formation

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Spatial epitope barcoding reveals clonal tumor patch behaviors

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GSK3β Inhibition Is the Molecular Pivot That Underlies the Mir-210-Induced Attenuation of Intrinsic Apoptosis Cascade during Hypoxia

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Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS

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May 2022
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A highland-adaptation mutation of the Epas1 protein increases its stability and disrupts the circadian clock in the plateau pika

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Carbamazepine promotes surface expression of mutant Kir6.2-A28V ATP-sensitive potassium channels by modulating Golgi retention and autophagy

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Reconstitution System of NLRP3 Inflammasome in HEK293T Cells

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CTNNBL1 restricts HIV-1 replication by suppressing viral DNA integration into the cell genome

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Structural basis for channel conduction in the pump-like channelrhodopsin ChRmine

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Translocation of TMEM175 Lysosomal Potassium Channel to the Plasma Membrane by Dynasore Compounds

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Genome editing in archaeal viruses and endogenous viral protein purification

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δ-protocadherins regulate neural progenitor cell division by antagonizing Ryk and Wnt/β-catenin signaling

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Untitled document

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Untitled document

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A novel human Cdh1 mutation impairs anaphase promoting complex/cyclosome (APC/C) activity resulting in microcephaly, psychomotor retardation and epilepsy

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A Bifunctional Role for the UHRF1 UBL Domain in the Control of Hemi-methylated DNA-Dependent Histone Ubiquitylation

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The Diverged Trypanosome MICOS Complex as a Hub for Mitochondrial Cristae Shaping and Protein Import

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Apical intercalated cell cluster: A distinct sensory regulator in the amygdala

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  RRID:AB_1097802126183
  
  DOI: 10.1016/j.celrep.2021.109151
  
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Histone Deacetylase 3 Couples Mitochondria to Drive IL-1β-Dependent Inflammation by Configuring Fatty Acid Oxidation

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A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation

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A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development

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Ogt controls neural stem/progenitor cell pool and adult neurogenesis through modulating Notch signaling

1
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A Novel Cortical Mechanism for Top-Down Control of Water Intake

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cell.com/current-biology/abstract/S0960-9822(20)31342-7
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Molecular Basis of Zinc-Dependent Endocytosis of Human ZIP4 Transceptor

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Structural basis of substrate recognition by a polypeptide processing and secretion transporter

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  DOI: 10.7554/eLife.51492
  
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Evolutionary Persistence of DNA Methylation for Millions of Years after Ancient Loss of a De Novo Methyltransferase

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sciencedirect.com/science/article/pii/S0092867419313741
Jan 2020
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The Heat Shock Response in Yeast Maintains Protein Homeostasis by Chaperoning and Replenishing Proteins

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1. scibot 13 Jan 2020
  
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  RRID:AB_10978021
  
  DOI: 10.1016/j.celrep.2019.11.109
  
  Resource: (Thermo Fisher Scientific Cat# 26183, RRID:AB_10978021)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S2211124719316328
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Untitled document

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1. scibot 12 Jan 2020
  
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  RRID:AB_10978021
  
  DOI: 10.1016/j.molcel.2019.01.008
  
  Resource: (Thermo Fisher Scientific Cat# 26183, RRID:AB_10978021)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1097276519300085
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Lhx1-Ldb1 complex interacts with Furry to regulate microRNA expression during pronephric kidney development

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1. scibot 05 Nov 2018
  
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  RRID:AB_10978021
  
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  (Thermo Fisher Scientific Cat# 26183, RRID:AB_10978021)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6207768/
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A compartmentalized signaling network mediates crossover control in meiosis

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1. scibot 05 Nov 2018
  
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  RRID:AB_10978021
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5906097/
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The Augmented R-Loop Is a Unifying Mechanism for Myelodysplastic Syndromes Induced by High-Risk Splicing Factor Mutations

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1. scibot 05 Nov 2018
  
  in Public
  
  RRID:AB_10978021
  
  Curator: @Jmenke
  
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  (Thermo Fisher Scientific Cat# 26183, RRID:AB_10978021)
  
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Nov 2017
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Mitochondrial Ferredoxin Determines Vulnerability of Cells to Copper Excess

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1. scibot 08 Nov 2017
  
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  RRID:AB_10978021
  
  Curator: @Jmenke
  
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The RNA Surveillance Factor UPF1 Represses Myogenesis via Its E3 Ubiquitin Ligase Activity

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1. scibot 08 Nov 2017
  
  in Public
  
  Anti-HAThermo2-2.2.14, 26183
  
  Curator: @Jmenke
  
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