76 Matching Annotations
  1. Sep 2026
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    FoxO transcription factors coordinate the urea cycle and gluconeogenesis by controlling Ass1
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  3. Jul 2026
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    2026.07.11.737985.full-html.html
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    AI-driven therapeutic antisense oligonucleotide for processing-deficient progeroid laminopathies
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    Arc mediates intercellular tau transmission via extracellular vesicles
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  7. May 2026
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    Transcription and cohesin direct domain boundary spatial positioning and are linked to Friedreich’s ataxia
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  9. Apr 2026
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  11. Mar 2026
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    Generation of the human induced pluripotent stem cell (hiPSC) line AUMCi015-A from a heterozygous carrier of the LMNA p.Q493X rare pathogenic variant
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  13. Feb 2026
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    Single-cell multi-omic analyses highlight the essential role of NKX2.2-CLEC16A/endosomal pathway for human pancreatic differentiation and function
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  15. Jan 2026
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    Extracellular matrix stiffness drives post-mitotic nuclear pore complex assembly to promote neuroblastoma pathogenesis
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    Calcium waves and nuclear tension changes coordinate mechanical stress dissipation in locally folded epithelia
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    RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria
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    pmc.ncbi.nlm.nih.gov/articles/PMC12952242/
  19. Dec 2025
  20. 54.241.53.176 54.241.53.176
    2025.11.26.690669v1.full-html.html
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  21. Nov 2025
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    Phenotype specific nuclear lamina remodeling in hiPSC derived cardiomyocytes bearing TNNT2 sarcomeric variants
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    Nuclear-lamin-guided plastic positioning and folding of the human genome
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  24. Oct 2025
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    Nuclear U1 snRNA facilitates the dimerization of hnRNPA2B1 to enhance anti-DNA viral innate immunity
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  26. Sep 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Recycling endosomes in mature epithelia restrain tumorigenic signaling
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  28. Aug 2025
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  30. Jul 2025
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    MSN/STAT3 drives cancer stemness and chemoresistance via IL-6/LPAR1 ligand receptor complex in triple-negative breast cancer
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    Protocol for induction and study of DNA double-strand breaks in mammalian cells using PALM microdissection and expansion microscopy
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  33. Jun 2025
  34. 52.53.155.43 52.53.155.43
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  35. Apr 2025
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    SLIRP amplifies antiviral signaling via positive feedback regulation and contributes to autoimmune diseases
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  37. Feb 2025
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    p27Kip1 and Tumors: Characterization of CDKN1B Variants Identified in MEN4 and Breast Cancer
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    Adipocyte-specific Steap4 deficiency reduced thermogenesis and energy expenditure in mice
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  40. Dec 2024
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    Peroxiredoxin 1-Toll-like receptor 4-p65 axis inhibits receptor activator of nuclear factor kappa-B ligand-mediated osteoclast differentiation
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  42. Sep 2024
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    Macrophage NRF1 promotes mitochondrial protein turnover via the ubiquitin proteasome system to limit mitochondrial stress and inflammation
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    Lamin chromatin binding is modulated by interactions of different LAP2α domains with lamins and chromatin
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  45. Jul 2024
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    RNA 5-methylcytosine marks mitochondrial double-stranded RNAs for degradation and cytosolic release
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    A mammalian model reveals inorganic polyphosphate channeling into the nucleolus and induction of a hyper-condensate state
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  48. Jun 2024
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    Pervasive nuclear envelope ruptures precede ECM signaling and disease onset without activating cGAS-STING in Lamin-cardiomyopathy mice
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  50. May 2024
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    Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite
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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cystatin C loaded in brain-derived extracellular vesicles rescues synapses after ischemic insult in vitro and in vivo
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  53. Apr 2024
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    Multi-omic profiling reveals the endogenous and neoplastic responses to immunotherapies in cutaneous T cell lymphoma
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  55. Mar 2024
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromatin-associated SIN3B protects cancer cells from genotoxic stress-induced apoptosis and dictates DNA damage repair pathway choice
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  57. Feb 2024
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    Alternative polyadenylation determines the functional landscape of inverted Alu repeats
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  59. Jan 2024
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    Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation
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    A membrane-sensing mechanism links lipid metabolism to protein degradation at the nuclear envelope
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  62. Sep 2023
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    Enhanced cell viscosity: A new phenotype associated with lamin A/C alterations
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  64. Aug 2023
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  66. Jul 2023
  67. www.cell.com www.cell.com
    Human embryo live imaging reveals nuclear DNA shedding during blastocyst expansion and biopsy
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    cell.com/cell/fulltext/S0092-8674(23)00643-8
  68. Feb 2023
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    Human IRF1 governs macrophagic IFN-γ immunity to mycobacteria
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  70. Jan 2023
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    EMC3 regulates mesenchymal cell survival via control of the mitotic spindle assembly
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    ncbi.nlm.nih.gov/pmc/articles/PMC9823123/
  72. Sep 2022
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    Confined migration induces heterochromatin formation and alters chromatin accessibility
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  74. Aug 2022
  75. www.nature.com www.nature.com
    Isolation of mitochondria-derived mitovesicles and subpopulations of microvesicles and exosomes from brain tissues
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    nature.com/articles/s41596-022-00719-1
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    Mitochondrial double-stranded RNAs govern the stress response in chondrocytes to promote osteoarthritis development
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  77. Jul 2022
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    Sex Differentially Alters Secretion of Brain Extracellular Vesicles During Aging: A Potential Mechanism for Maintaining Brain Homeostasis
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    link.springer.com/article/10.1007/s11064-022-03701-1
  79. May 2022
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    Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging
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  81. Mar 2022
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    The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity
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  83. Feb 2022
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    SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage
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  85. Dec 2021
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    Defective brown adipose tissue thermogenesis and impaired glucose metabolism in mice lacking Letmd1
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  88. Oct 2021
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    Global chromatin relabeling accompanies spatial inversion of chromatin in rod photoreceptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC8462898/
  90. Sep 2021
  91. www.science.org www.science.org
    Global chromatin relabeling accompanies spatial inversion of chromatin in rod photoreceptors
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    science.org/doi/abs/10.1126/sciadv.abj3035
  92. Aug 2021
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    The non-muscle ADF/cofilin-1 controls sarcomeric actin filament integrity and force production in striated muscle laminopathies
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  94. Jul 2021
  95. www.nature.com www.nature.com
    Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction
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    nature.com/articles/s41422-019-0213-0
  96. May 2021
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    Pathogenic LMNA variants disrupt cardiac lamina-chromatin interactions and de-repress alternative fate genes
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  98. Apr 2021
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    Acetylation of Cytidine Residues Boosts HIV-1 Gene Expression by Increasing Viral RNA Stability
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    Telomere Stress Potentiates STING-Dependent Anti-tumor Immunity
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    Impact of chromatin context on Cas9-induced DNA double-strand break repair pathway balance
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    ncbi.nlm.nih.gov/pmc/articles/PMC8153251/
  102. Mar 2021
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early postnatal interactions between beige adipocytes and sympathetic neurites regulate innervation of subcutaneous fat
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    ncbi.nlm.nih.gov/pmc/articles/PMC7990502/
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LAP2alpha maintains a mobile and low assembly state of A-type lamins in the nuclear interior
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    ncbi.nlm.nih.gov/pmc/articles/PMC7939549/
  105. Feb 2021
  106. academic.oup.com academic.oup.com
    Multisystem Progeroid Syndrome With Lipodystrophy, Cardiomyopathy, and Nephropathy Due to an LMNA p.R349W Variant
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    academic.oup.com/jes/article/4/10/bvaa104/5876856
  107. www.cell.com www.cell.com
    Nuclear Deformation Causes DNA Damage by Increasing Replication Stress
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    cell.com/current-biology/fulltext/S0960-9822(20)31748-6
  108. Dec 2020
  109. www.sciencedirect.com www.sciencedirect.com
    Human VAPome Analysis Reveals MOSPD1 and MOSPD3 as Membrane Contact Site Proteins Interacting with FFAT-Related FFNT Motifs
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  110. Nov 2020
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    De Novo VPS4A Mutations Cause Multisystem Disease with Abnormal Neurodevelopment
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  112. Sep 2020
  113. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Recycling endosomes in mature epithelia restrain tumorigenic signaling
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  114. www.sciencedirect.com www.sciencedirect.com
    Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria
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    SFTSV Infection Induces BAK/BAX-Dependent Mitochondrial DNA Release to Trigger NLRP3 Inflammasome Activation
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sodium butyrate inhibits high cholesterol-induced neuronal amyloidogenesis by modulating NRF2 stabilization-mediated ROS levels: involvement of NOX2 and SOD1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7303181/
  117. Jan 2020
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    H3K9me2 orchestrates inheritance of spatial positioning of peripheral heterochromatin through mitosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC6795522/
  119. www.cell.com www.cell.com
    miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer
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    cell.com/cell-reports/fulltext/S2211-1247(19)31576-1
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    TATA-Box Binding Protein O-GlcNAcylation at T114 Regulates Formation of the B-TFIID Complex and Is Critical for Metabolic Gene Regulation
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    AUTACs: Cargo-Specific Degraders Using Selective Autophagy
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