172 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microglia-derived ADAM9 promote GHRH neurons pyroptosis by Mad2L2-JNK-caspase-1 pathway in subarachnoid hemorrhage
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    1. scibot 21 Nov 2024
      AB_10999090

      DOI: 10.1186/s12974-024-03299-x

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    pmc.ncbi.nlm.nih.gov/articles/PMC11575213/
  3. Nov 2024
  4. www.sciencedirect.com www.sciencedirect.com
    A PROTAC degrader suppresses oncogenic functions of PTK6 inducing apoptosis of breast cancer cells
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    1. scibot 14 Nov 2024
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      DOI: 10.1016/j.chembiol.2024.10.008

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    sciencedirect.com/science/article/pii/S2451945624004434
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Insulin Mediates Lipopolysaccharide-Induced Inflammatory Responses and Oxidative Stress in BV2 Microglia
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    1. scibot 10 Nov 2024
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      DOI: 10.2147/JIR.S481101

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    pmc.ncbi.nlm.nih.gov/articles/PMC11539848/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neurons enhance blood–brain barrier function via upregulating claudin-5 and VE-cadherin expression due to glial cell line-derived neurotrophic factor secretion
    1
    1. scibot 07 Nov 2024
      RRID:AB_10999090

      DOI: 10.7554/eLife.96161

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  7. Sep 2024
  8. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    1. scibot 25 Sep 2024
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      DOI: 10.1111/bph.15169

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    2. scibot 25 Sep 2024
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      DOI: 10.1111/bph.15169

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      Curator comments: Phospho-p38 MAPK (Thr180/Tyr182) (D3F9) XP Rabbit mAb antibody Cell Signaling Technology Cat# 4511

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15169
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hesperetin but not ellagic acid increases myosin heavy chain expression and cell fusion in C2C12 myoblasts in the presence of oxidative stress
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    1. scibot 18 Sep 2024
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      DOI: 10.3389/fnut.2024.1377071

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    ncbi.nlm.nih.gov/pmc/articles/PMC11402829/
  10. www.sciencedirect.com www.sciencedirect.com
    Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma
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    1. scibot 12 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114721

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    sciencedirect.com/science/article/pii/S2211124724010726
  11. Aug 2024
  12. www.sciencedirect.com www.sciencedirect.com
    MOF-mediated PRDX1 acetylation regulates inflammatory macrophage activation
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    1. scibot 29 Aug 2024
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    sciencedirect.com/science/article/pii/S2211124724010337
  13. Jul 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apocynin Prevents Cigarette Smoke-Induced Anxiety-Like Behavior and Preserves Microglial Profiles in Male Mice
    1
    1. scibot 30 Jul 2024
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      DOI: 10.3390/antiox13070855

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    ncbi.nlm.nih.gov/pmc/articles/PMC11274253/
  15. Jun 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 envelope protein regulates innate immune tolerance
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    1. scibot 08 Jun 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11140213/
  17. www.sciencedirect.com www.sciencedirect.com
    Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1
    1
    1. scibot 08 Jun 2024
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      DOI: 10.1016/j.isci.2024.109828

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    sciencedirect.com/science/article/pii/S2589004224010502
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress
    1
    1. scibot 03 Jun 2024
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  19. May 2024
  20. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Monocarboxylate transporter 4 deficiency enhances high-intensity interval training-induced metabolic adaptations in skeletal muscle
    1
    1. scibot 24 May 2024
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      DOI: 10.1113/JP285719

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP285719
  21. 52.53.155.43 52.53.155.43
    TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis
    2
    1. scibot 17 May 2024
      RRID:AB_10999090

      DOI: 10.20944/preprints202402.1027.v1

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      DOI: 10.20944/preprints202402.1027.v1

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    52.53.155.43/86d6d1effc82110b06a7585d839c944adff76cc8/preprints202402.1027.v1-html.html
  22. www.biorxiv.org www.biorxiv.org
    Neurons enhance blood-brain barrier function via upregulating claudin-5 and VE-cadherin expression due to GDNF secretion
    2
    1. scibot 10 May 2024
      RRID:AB_10999090

      DOI: 10.1101/2024.02.07.579396

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      DOI: 10.1101/2024.02.07.579396

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    biorxiv.org/content/10.1101/2024.02.07.579396v1
  23. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 03 May 2024
      RRID:AB_10999090

      DOI: 10.1111/bph.16356

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16356
  24. Apr 2024
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling
    1
    1. scibot 27 Apr 2024
      AB_10999090

      DOI: 10.7554/eLife.94265

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    ncbi.nlm.nih.gov/pmc/articles/PMC11045221/
  26. www.sciencedirect.com www.sciencedirect.com
    Turnover of PPP1R15A mRNA encoding GADD34 controls responsiveness and adaptation to cellular stress
    1
    1. scibot 12 Apr 2024
      RRID:AB_10999090

      DOI: 10.1016/j.celrep.2024.114069

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    sciencedirect.com/science/article/pii/S2211124724003978
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis
    1
    1. scibot 03 Apr 2024
      RRID:AB_10999090

      DOI: 10.3390/ijms25063343

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    ncbi.nlm.nih.gov/pmc/articles/PMC10970352/
  28. www.sciencedirect.com www.sciencedirect.com
    Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome
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    1. scibot 02 Apr 2024
      RRID:AB_10999090

      DOI: 10.1016/j.jare.2024.03.019

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      DOI: 10.1016/j.jare.2024.03.019

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    sciencedirect.com/science/article/pii/S209012322400119X
  29. Mar 2024
  30. 52.53.155.43 52.53.155.43
    Human seminal extracellular vesicles enhance endometrial receptivity through leukemia inhibitory factor
    2
    1. scibot 29 Mar 2024
      AB_10999090

      DOI: 10.1210/endocr/bqae035

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      DOI: 10.1210/endocr/bqae035

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    52.53.155.43/ef706d7fedeb9d14a9f80c03d77786b7f4c289d6/bqae035-html.html
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis
    1
    1. scibot 19 Mar 2024
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      DOI: 10.1038/s41467-024-46602-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10944492/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer's and related dementias
    1
    1. scibot 16 Mar 2024
      RRID:AB_10999090

      DOI: 10.1038/s44319-024-00077-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10933458/
  33. Feb 2024
  34. www.sciencedirect.com www.sciencedirect.com
    Gut microbial co-metabolite 2-methylbutyrylcarnitine exacerbates thrombosis via binding to and activating integrin α2β1
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    1. scibot 27 Feb 2024
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      DOI: 10.1016/j.cmet.2024.01.014

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    sciencedirect.com/science/article/abs/pii/S1550413124000147
  35. www.embopress.org www.embopress.org
    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer’s and related dementias
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    1. scibot 15 Feb 2024
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      DOI: 10.1038/s44319-024-00077-x

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    embopress.org/doi/10.1038/s44319-024-00077-x
  36. www.sciencedirect.com www.sciencedirect.com
    Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans
    1
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      DOI: 10.1016/j.cmet.2023.10.018

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    sciencedirect.com/science/article/pii/S1550413123004126
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OVOL2 induces autophagy-mediated epithelial-mesenchymal transition by the ERK1/2 MAPK signaling in lung adenocarcinoma
    1
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      DOI: 10.1016/j.isci.2024.108873

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    ncbi.nlm.nih.gov/pmc/articles/PMC10838806/
  38. Jan 2024
  39. www.sciencedirect.com www.sciencedirect.com
    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
    1
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      DOI: 10.1016/j.xcrm.2023.101388

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    sciencedirect.com/science/article/pii/S2666379123006171
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    O6-Methylguanine DNA Methyltransferase Regulates β-glucan-induced Trained Immunity of Macrophages via Farnesoid X Receptor and AMPK
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    1. scibot 20 Jan 2024
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      DOI: 10.1016/j.isci.2023.108733

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    ncbi.nlm.nih.gov/pmc/articles/PMC10792243/
  41. www.sciencedirect.com www.sciencedirect.com
    Selective induction of human renal interstitial progenitor-like cell lineages from iPSCs reveals development of mesangial and EPO-producing cells
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      DOI: 10.1016/j.celrep.2023.113602

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    sciencedirect.com/science/article/pii/S2211124723016145
  42. www.sciencedirect.com www.sciencedirect.com
    Metformin inhibits cell proliferation and ACTH secretion in AtT20 cells via regulating the MAPK pathway
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      DOI: 10.1016/j.mce.2023.112140

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      DOI: 10.1016/j.mce.2023.112140

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    sciencedirect.com/science/article/pii/S0303720723002915
  43. Nov 2023
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways
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    1. scibot 30 Nov 2023
      RRID:AB_10999090

      DOI: 10.1186/s40779-023-00494-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10675918/
  45. www.sciencedirect.com www.sciencedirect.com
    Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer
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      DOI: 10.1016/j.isci.2023.108399

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    sciencedirect.com/science/article/pii/S2589004223024768
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ANKRD49 promotes the metastasis of NSCLC via activating JNK-ATF2/c-Jun-MMP-2/9 axis
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      DOI: 10.1186/s12885-023-11612-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10644579/
  47. Oct 2023
  48. www.sciencedirect.com www.sciencedirect.com
    CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression
    1
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    Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma
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    Proteomic-Based Approach Reveals the Involvement of Apolipoprotein A-I in Related Phenotypes of Autism Spectrum Disorder in the BTBR Mouse Model
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  95. Nov 2022
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    Inhibition of glutaminolysis restores mitochondrial function in senescent stem cells
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    TREM2 improves neurological dysfunction and attenuates neuroinflammation, TLR signaling and neuronal apoptosis in the acute phase of intracerebral hemorrhage
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  103. Sep 2022
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    cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells
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  114. Apr 2022
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    The GADD45G/p38 MAPK/CDC25B signaling pathway enhances neurite outgrowth by promoting microtubule polymerization
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    Bone erosion in inflammatory arthritis is attenuated by Trichinella spiralis through inhibiting M1 monocyte/macrophage polarization
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  123. Feb 2022
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  130. Nov 2021
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  133. Oct 2021
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  135. Sep 2021
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    Nitric Oxide Induces a Janus Kinase-1-Dependent Inflammatory Response in Primary Murine Astrocytes - John D. Nowery, Rylee N. Cisney, Jacob W. Feldmann, Gordon P. Meares, 2021
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  137. Aug 2021
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    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
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  144. Jul 2021
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    ANGPTL2 Promotes Inflammation via Integrin α5β1 in Chondrocytes - Mami Takano, Naoto Hirose, Chikako Sumi, Makoto Yanoshita, Sayuri Nishiyama, Azusa Onishi, Yuki Asakawa, Kotaro Tanimoto,
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    Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8
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  149. www.sciencedirect.com www.sciencedirect.com
    Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2
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      RRID:AB_1099909

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  150. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuronal activity‐dependent local activation of dendritic unfolded protein response promotes expression of brain‐derived neurotrophic factor in cell soma
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      RRID:AB_10998134

      DOI: 10.1111/jnc.14221

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  151. www.sciencedirect.com www.sciencedirect.com
    An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress
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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-17 Inhibits Oligodendrocyte Progenitor Cell Proliferation and Differentiation by Increasing K+ Channel Kv1.3
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      DOI: 10.3389/fncel.2021.679413

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  153. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  154. www.cell.com www.cell.com
    Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer
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  155. Jun 2021
  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Flightless I is a catabolic factor of chondrocytes that promotes hypertrophy and cartilage degeneration in osteoarthritis
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  157. www.sciencedirect.com www.sciencedirect.com
    Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma
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  158. May 2021
  159. www.sciencedirect.com www.sciencedirect.com
    The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation
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    SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells
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    Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation
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    Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation
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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hydroxychloroquine Inhibits Macrophage Activation and Attenuates Renal Fibrosis After Ischemia-Reperfusion Injury
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  164. Apr 2021
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    Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer
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  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optogenetic activation of spinal microglia triggers chronic pain in mice
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  167. Mar 2021
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    Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock
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  169. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  170. Feb 2021
  171. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Astaxanthin ameliorates oxidative stress and neuronal apoptosis via SIRT1/Nrf2/Prx2/ASK1/P38 after traumatic brain injury in mice
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  172. www.sciencedirect.com www.sciencedirect.com
    Induction of UCP1 and thermogenesis by a small molecule via AKAP1/PKA modulation
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      total p38 MAPK

      DOI: 10.1074/jbc.RA120.013322

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  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-L1 Reverse Signaling in Dermal Dendritic Cells Promotes Dendritic Cell Migration Required for Skin Immunity
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    Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination
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  175. Nov 2020
  176. www.frontiersin.org www.frontiersin.org
    Polyunsaturated Fatty Acids Influence LPS-Induced Inflammation of Fish Macrophages Through Differential Modulation of Pathogen Recognition and p38 MAPK/NF-κB Signaling
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  177. Oct 2020
  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-Transcriptional and Translational Function of Canonical NF-κB Signaling in Activating ERK1/2 in IL-1β-Induced COX-2 Expression in Synovial Fibroblasts
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    Activation of EphrinB2 Signaling Promotes Adaptive Venous Remodeling in Murine Arteriovenous Fistulae
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      RRID:AB_10999090

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  180. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    The p38 signaling pathway mediates the TGF‐β1‐induced increase in type I collagen deposition in human granulosa cells
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      DOI: 10.1096/fj.202001377R

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  181. Sep 2020
  182. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Arctigenin protects mice from thioglycollate‐induced acute peritonitis
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  183. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FGF21 impedes peripheral myelin development by stimulating p38 MAPK/c‐Jun axis
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  184. academic.oup.com academic.oup.com
    Chaperone-mediated autophagy governs progression of papillary thyroid carcinoma via PPARγ-SDF1/CXCR4 signaling
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    Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2
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    Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling
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  187. Jan 2020
  188. www.sciencedirect.com www.sciencedirect.com
    Immune Sensing of Cell Death through Recognition of Histone Sequences by C-Type Lectin-Receptor-2d Causes Inflammation and Tissue Injury
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    CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation
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    Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK
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    Hepatic nitric oxide synthase 1 adaptor protein regulates glucose homeostasis and hepatic insulin sensitivity in obese mice depending on its PDZ binding domain
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    GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis
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    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
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    Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy
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    Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis
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      DOI: 10.1016/j.cmet.2019.11.013

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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Natural molecules induce and synergize to boost expression of the human antimicrobial peptide β-defensin-3
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      DOI: 10.1073/pnas.1805298115

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  197. www.nature.com www.nature.com
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  198. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      DOI: 10.1002/jcp.28051

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  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.3389/fneur.2019.00099

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  200. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.chembiol.2019.03.009

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  201. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.devcel.2019.04.015

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  202. www.sciencedirect.com www.sciencedirect.com
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  203. www.sciencedirect.com www.sciencedirect.com
    Dynamic UTR Usage Regulates Alternative Translation to Modulate Gap Junction Formation during Stress and Aging
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      DOI: 10.1016/j.celrep.2019.04.114

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  204. elifesciences.org elifesciences.org
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      DOI: 10.7554/eLife.40396

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  205. Nov 2018
  206. onlinelibrary.wiley.com onlinelibrary.wiley.com
    High expression of glutamate‐ammonia ligase is associated with unfavorable prognosis in patients with ovarian cancer
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  207. Nov 2017
  208. www.sciencedirect.com www.sciencedirect.com
    Divergent JNK Phosphorylation of HDAC3 in Triple-Negative Breast Cancer Cells Determines HDAC Inhibitor Binding and Selectivity
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  209. www.sciencedirect.com www.sciencedirect.com
    A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
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  210. www.sciencedirect.com www.sciencedirect.com
    Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma
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  211. onlinelibrary.wiley.com onlinelibrary.wiley.com
    GLUL Promotes Cell Proliferation in Breast Cancer
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    onlinelibrary.wiley.com/doi/10.1002/jcb.25775/full
  212. www.nature.com www.nature.com
    A simple optogenetic MAPK inhibitor design reveals resonance between transcription-regulating circuitry and temporally-encoded inputs
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      Curator: @Zeljana_Babic

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