152 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Turnover of PPP1R15A mRNA encoding GADD34 controls responsiveness and adaptation to cellular stress
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    1. scibot 12 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114069

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    sciencedirect.com/science/article/pii/S2211124724003978
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis
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    1. scibot 03 Apr 2024
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      DOI: 10.3390/ijms25063343

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    ncbi.nlm.nih.gov/pmc/articles/PMC10970352/
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    Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome
    2
    1. scibot 02 Apr 2024
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      DOI: 10.1016/j.jare.2024.03.019

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    2. scibot 02 Apr 2024
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      DOI: 10.1016/j.jare.2024.03.019

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    sciencedirect.com/science/article/pii/S209012322400119X
  5. Mar 2024
  6. 52.53.155.43 52.53.155.43
    Human seminal extracellular vesicles enhance endometrial receptivity through leukemia inhibitory factor
    2
    1. scibot 29 Mar 2024
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      DOI: 10.1210/endocr/bqae035

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    2. scibot 29 Mar 2024
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      DOI: 10.1210/endocr/bqae035

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    52.53.155.43/ef706d7fedeb9d14a9f80c03d77786b7f4c289d6/bqae035-html.html
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis
    1
    1. scibot 19 Mar 2024
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      DOI: 10.1038/s41467-024-46602-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10944492/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer's and related dementias
    1
    1. scibot 16 Mar 2024
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      DOI: 10.1038/s44319-024-00077-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10933458/
  9. Feb 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Gut microbial co-metabolite 2-methylbutyrylcarnitine exacerbates thrombosis via binding to and activating integrin α2β1
    1
    1. scibot 27 Feb 2024
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      DOI: 10.1016/j.cmet.2024.01.014

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    sciencedirect.com/science/article/abs/pii/S1550413124000147
  11. www.embopress.org www.embopress.org
    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer’s and related dementias
    1
    1. scibot 15 Feb 2024
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      DOI: 10.1038/s44319-024-00077-x

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    embopress.org/doi/10.1038/s44319-024-00077-x
  12. www.sciencedirect.com www.sciencedirect.com
    Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.cmet.2023.10.018

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    sciencedirect.com/science/article/pii/S1550413123004126
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OVOL2 induces autophagy-mediated epithelial-mesenchymal transition by the ERK1/2 MAPK signaling in lung adenocarcinoma
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.isci.2024.108873

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    ncbi.nlm.nih.gov/pmc/articles/PMC10838806/
  14. Jan 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
    1
    1. scibot 23 Jan 2024
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      DOI: 10.1016/j.xcrm.2023.101388

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    sciencedirect.com/science/article/pii/S2666379123006171
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    O6-Methylguanine DNA Methyltransferase Regulates β-glucan-induced Trained Immunity of Macrophages via Farnesoid X Receptor and AMPK
    1
    1. scibot 20 Jan 2024
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      DOI: 10.1016/j.isci.2023.108733

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    ncbi.nlm.nih.gov/pmc/articles/PMC10792243/
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    Selective induction of human renal interstitial progenitor-like cell lineages from iPSCs reveals development of mesangial and EPO-producing cells
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113602

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    sciencedirect.com/science/article/pii/S2211124723016145
  18. www.sciencedirect.com www.sciencedirect.com
    Metformin inhibits cell proliferation and ACTH secretion in AtT20 cells via regulating the MAPK pathway
    2
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.mce.2023.112140

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      DOI: 10.1016/j.mce.2023.112140

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    sciencedirect.com/science/article/pii/S0303720723002915
  19. Nov 2023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways
    1
    1. scibot 30 Nov 2023
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      DOI: 10.1186/s40779-023-00494-4

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    ncbi.nlm.nih.gov/pmc/articles/PMC10675918/
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    Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.isci.2023.108399

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    sciencedirect.com/science/article/pii/S2589004223024768
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ANKRD49 promotes the metastasis of NSCLC via activating JNK-ATF2/c-Jun-MMP-2/9 axis
    1
    1. scibot 16 Nov 2023
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      DOI: 10.1186/s12885-023-11612-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10644579/
  23. Oct 2023
  24. www.sciencedirect.com www.sciencedirect.com
    CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.cmet.2023.09.012

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    sciencedirect.com/science/article/pii/S1550413123003686
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the JNK/COX-2/HIF-1α axis promotes M1 macrophage via glycolytic shift in HIV-1 infection
    1
    1. scibot 12 Oct 2023
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      DOI: 10.26508/lsa.202302148

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    ncbi.nlm.nih.gov/pmc/articles/PMC10556724/
  26. aiche.onlinelibrary.wiley.com aiche.onlinelibrary.wiley.com
    Mechanochemical coupling of MGF mediates periodontal regeneration
    1
    1. scibot 09 Oct 2023
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      DOI: 10.1002/btm2.10603

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    aiche.onlinelibrary.wiley.com/doi/10.1002/btm2.10603
  27. www.cell.com www.cell.com
    The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113081

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    cell.com/cell-reports/abstract/S2211-1247(23)01092-6
  28. Sep 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    URAT1 is expressed in cardiomyocytes and dotinurad attenuates the development of diet-induced metabolic heart disease.
    1
    1. scibot 09 Sep 2023
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      DOI: 10.1016/j.isci.2023.107730

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    ncbi.nlm.nih.gov/pmc/articles/PMC10483053/
  30. www.sciencedirect.com www.sciencedirect.com
    CGK733 alleviates ovariectomy-induced bone loss through blocking RANKL-mediated Ca2+ oscillations and NF-κB/MAPK signaling pathways
    1
    1. scibot 08 Sep 2023
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      DOI: 10.1016/j.isci.2023.107760

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    sciencedirect.com/science/article/pii/S2589004223018370
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucose Transporter-2 Regulation of Male versus Female Hypothalamic Astrocyte MAPK Expression and Activation: Impact of Glucose
    1
    1. scibot 07 Sep 2023
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      DOI: 10.3390/neuroglia4030011

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    ncbi.nlm.nih.gov/pmc/articles/PMC10361449/
  32. Aug 2023
  33. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Yang-html.html
    1
    1. scibot 16 Aug 2023
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      DOI: 10.1111/bph.16217

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    52.53.155.43/ebaf450bc55b2dfbcc4f1c7a194e3583ce7f4fc5/British J Pharmacology - 2023 - Yang-html.html
  34. Jul 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia
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    1. scibot 27 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112869

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    sciencedirect.com/science/article/pii/S221112472300880X
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    Caffeoylquinic acids isolated from Lonicera japonica Thunb. as TAK1 inhibitors protects against LPS plus IFN-γ-stimulated inflammation by interacting with KEAP1-regulated NRF2 activation
    1
    1. scibot 07 Jul 2023
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      DOI: 10.1016/j.biopha.2023.115038

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    sciencedirect.com/science/article/pii/S0753332223008284
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    Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin
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    1. scibot 06 Jul 2023
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      DOI: 10.1016/j.immuni.2023.06.006

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    sciencedirect.com/science/article/pii/S1074761323002637
  38. Jun 2023
  39. www.mdpi.com www.mdpi.com
    Effects of Dietary Oleacein Treatment on Endothelial Dysfunction and Lupus Nephritis in Balb/C Pristane-Induced Mice
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    1. scibot 23 Jun 2023
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      DOI: 10.3390/antiox12061303

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    mdpi.com/2076-3921/12/6/1303
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    Identification of an IL-1 receptor mutation driving autoinflammation directs IL-1-targeted drug design
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      DOI: 10.1016/j.immuni.2023.05.014

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    sciencedirect.com/science/article/pii/S1074761323002315
  41. www.sciencedirect.com www.sciencedirect.com
    Acetate controls endothelial-to-mesenchymal transition
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      DOI: 10.1016/j.cmet.2023.05.010

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    sciencedirect.com/science/article/pii/S1550413123002036
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    UBE2M-mediated neddylation of TRIM21 regulates obesity-induced inflammation and metabolic disorders
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      DOI: 10.1016/j.cmet.2023.05.011

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    sciencedirect.com/science/article/pii/S1550413123002097
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    SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury
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      DOI: 10.1016/j.isci.2023.106953

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    sciencedirect.com/science/article/pii/S2589004223010301
  44. www.cell.com www.cell.com
    Secreted Akkermansia muciniphila threonyl-tRNA synthetase functions to monitor and modulate immune homeostasis
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      DOI: 10.1016/j.chom.2023.05.007

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    cell.com/cell-host-microbe/fulltext/S1931-3128(23)00200-7
  45. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.16080

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16080
  46. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Targeting formyl peptide receptor 1 by anteiso-C13-surfactin for neutrophil-dominant acute respiratory distress syndrome
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      DOI: 10.1111/bph.16073

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16073
  47. May 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Heat promotes melanogenesis by increasing the paracrine effects in keratinocytes via the TRPV3/Ca2+/Hh signaling pathway
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    Proteomic-Based Approach Reveals the Involvement of Apolipoprotein A-I in Related Phenotypes of Autism Spectrum Disorder in the BTBR Mouse Model
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    Involvement of CCN1 Protein and TLR2/4 Signaling Pathways in Intestinal Epithelial Cells Response to Listeria monocytogenes
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  99. Feb 2022
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oxysterols Protect Epithelial Cells Against Pore-Forming Toxins
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    Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression
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  102. Jan 2022
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    Inhibition of transcription factor NFAT activity in activated platelets enhances their aggregation and exacerbates gram-negative bacterial septicemia
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  104. Dec 2021
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    Interleukin-17 affects synaptic plasticity and cognition in an experimental model of multiple sclerosis
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  106. Nov 2021
  107. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  108. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Differential ER Stress as a Driver of Cell Fate following Ricin Toxin Exposure
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  109. Oct 2021
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bletinib ameliorates neutrophilic inflammation and lung injury by inhibiting Src family kinase phosphorylation and activity
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  111. Sep 2021
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    Nitric Oxide Induces a Janus Kinase-1-Dependent Inflammatory Response in Primary Murine Astrocytes - John D. Nowery, Rylee N. Cisney, Jacob W. Feldmann, Gordon P. Meares, 2021
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  113. Aug 2021
  114. www.sciencedirect.com www.sciencedirect.com
    Mutations in the transcription factor FOXO1 mimic positive selection signals to promote germinal center B cell expansion and lymphomagenesis
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin G1 promotes pancreatic tumorigenesis through cancer associated fibroblast driven nutritional support and immunosuppression
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  116. academic.oup.com academic.oup.com
    Differential Actions of Estrogen Receptor α and β via Non-Genomic Signaling in Human Prostate Stem and Progenitor Cells
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    Mitogen‐activated protein kinase signaling mediates opioid‐induced presynaptic NMDA receptor activation and analgesic tolerance
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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
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  120. Jul 2021
  121. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Activation of spinal PDGFRβ in microglia promotes neuronal autophagy via p38 MAPK pathway in morphine-tolerant rats
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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  123. journals.sagepub.com journals.sagepub.com
    ANGPTL2 Promotes Inflammation via Integrin α5β1 in Chondrocytes - Mami Takano, Naoto Hirose, Chikako Sumi, Makoto Yanoshita, Sayuri Nishiyama, Azusa Onishi, Yuki Asakawa, Kotaro Tanimoto,
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  124. www.sciencedirect.com www.sciencedirect.com
    Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8
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    Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2
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  126. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuronal activity‐dependent local activation of dendritic unfolded protein response promotes expression of brain‐derived neurotrophic factor in cell soma
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      RRID:AB_10998134

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    An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress
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  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-17 Inhibits Oligodendrocyte Progenitor Cell Proliferation and Differentiation by Increasing K+ Channel Kv1.3
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  129. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  130. www.cell.com www.cell.com
    Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer
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  131. Jun 2021
  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Flightless I is a catabolic factor of chondrocytes that promotes hypertrophy and cartilage degeneration in osteoarthritis
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    Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma
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  134. May 2021
  135. www.sciencedirect.com www.sciencedirect.com
    The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation
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    SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells
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    Stabilization of ERK-Phosphorylated METTL3 by USP5 Increases m6A Methylation
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    Proline Hydroxylation Primes Protein Kinases for Autophosphorylation and Activation
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  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hydroxychloroquine Inhibits Macrophage Activation and Attenuates Renal Fibrosis After Ischemia-Reperfusion Injury
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  140. Apr 2021
  141. www.sciencedirect.com www.sciencedirect.com
    Neurons Release Serine to Support mRNA Translation in Pancreatic Cancer
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optogenetic activation of spinal microglia triggers chronic pain in mice
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  143. Mar 2021
  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pin1 Promotes NLRP3 Inflammasome Activation by Phosphorylation of p38 MAPK Pathway in Septic Shock
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  145. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  146. Feb 2021
  147. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Astaxanthin ameliorates oxidative stress and neuronal apoptosis via SIRT1/Nrf2/Prx2/ASK1/P38 after traumatic brain injury in mice
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  148. www.sciencedirect.com www.sciencedirect.com
    Induction of UCP1 and thermogenesis by a small molecule via AKAP1/PKA modulation
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      total p38 MAPK

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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  151. Nov 2020
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    Polyunsaturated Fatty Acids Influence LPS-Induced Inflammation of Fish Macrophages Through Differential Modulation of Pathogen Recognition and p38 MAPK/NF-κB Signaling
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  153. Oct 2020
  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-Transcriptional and Translational Function of Canonical NF-κB Signaling in Activating ERK1/2 in IL-1β-Induced COX-2 Expression in Synovial Fibroblasts
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    Activation of EphrinB2 Signaling Promotes Adaptive Venous Remodeling in Murine Arteriovenous Fistulae
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  156. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
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  157. Sep 2020
  158. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
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    Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2
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    Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling
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  163. Jan 2020
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    Immune Sensing of Cell Death through Recognition of Histone Sequences by C-Type Lectin-Receptor-2d Causes Inflammation and Tissue Injury
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    Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling
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    Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy
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    Dynamic UTR Usage Regulates Alternative Translation to Modulate Gap Junction Formation during Stress and Aging
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    High expression of glutamate‐ammonia ligase is associated with unfavorable prognosis in patients with ovarian cancer
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  183. Nov 2017
  184. www.sciencedirect.com www.sciencedirect.com
    Divergent JNK Phosphorylation of HDAC3 in Triple-Negative Breast Cancer Cells Determines HDAC Inhibitor Binding and Selectivity
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    A Dual Role of Caspase-8 in Triggering and Sensing Proliferation-Associated DNA Damage, a Key Determinant of Liver Cancer Development
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    Integrin α7 Is a Functional Marker and Potential Therapeutic Target in Glioblastoma
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    A simple optogenetic MAPK inhibitor design reveals resonance between transcription-regulating circuitry and temporally-encoded inputs
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