193 Matching Annotations
  1. Aug 2025
  2. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225016578-main-html.html
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    Nitroxoline upregulates low-density lipoprotein receptors expression, enhances lipid metabolism, and reduces hepatic steatosis and atherosclerosis in Apoe−/− mice
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    sciencedirect.com/science/article/pii/S0925443925003643
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    Microglia mediated by LAG3 regulate astrocyte morphogenesis in the brain white matter
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    sciencedirect.com/science/article/pii/S2211124725008836
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Scavenger Receptor CD36 in Tumor-Associated Macrophages Promotes Cancer Progression by Dampening Type I Interferon Signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC11788022/
  6. Jul 2025
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    Alistipes finegoldii augments the efficacy of immunotherapy against solid tumors
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    sciencedirect.com/science/article/pii/S1535610825002739
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    Using computational pharmacology and experimental verification to decode mechanism of Qing-Wei-San in treating periodontitis
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    link.springer.com/article/10.1186/s12906-025-04967-y
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NOD1 promotes leukocyte clearance and limits inflammation in female mice during obesity‐associated acute lung injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC12227658/
  10. Jun 2025
  11. www.sciencedirect.com www.sciencedirect.com
    Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy
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    sciencedirect.com/science/article/pii/S1074761325002274
  12. May 2025
  13. www.nature.com www.nature.com
    Decoding post-transcriptional regulatory networks by RNA-linked CRISPR screening in human cells
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    nature.com/articles/s41592-025-02702-6
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TNF‐α‐Driven Changes in Polarized EGF Receptor Trafficking Facilitate Phosphatidylinositol 3‐Kinase/Protein Kinase B Signaling From the Apical Surface of MDCK Epithelial Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12052438/
  15. Apr 2025
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    Scutellaria barbata ameliorates acute respiratory distress syndrome by inhibiting neutrophil-mediated inflammatory responses
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    sciencedirect.com/science/article/pii/S037887412500337X
  17. Mar 2025
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    Macrophage-specific PHGDH protects against MAFLD by suppressing TAK1
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    sciencedirect.com/science/article/pii/S2211124725001974
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    ENKD1 modulates innate immune responses through enhanced geranylgeranyl pyrophosphate synthase activity
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    sciencedirect.com/science/article/pii/S2211124725001688
  20. Feb 2025
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    Taste receptor type 1 member 3 in osteoclasts regulates osteoclastogenesis via detection of glucose
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    sciencedirect.com/science/article/pii/S0021925825001218
  22. Jan 2025
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    Negative regulation of lymphangiogenesis by Tenascin-C delays the resolution of inflammation
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    sciencedirect.com/science/article/pii/S258900422500015X
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    Histone acetylation alteration by KAT6A inhibitor WM-1119 suppresses IgE-mediated mast cell activation and allergic inflammation via reduction in AP-1 signaling
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    sciencedirect.com/science/article/pii/S0006295224007330
  25. Dec 2024
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    IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages
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    sciencedirect.com/science/article/pii/S2211124724013901
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    A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor
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    sciencedirect.com/science/article/pii/S0092867424013266
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    Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer
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    science.org/doi/10.1126/scisignal.adp1375
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    Integrative pathway analysis across humans and 3D cellular models identifies the p38 MAPK-MK2 axis as a therapeutic target for Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S0896627324008006
  30. Nov 2024
  31. www.sciencedirect.com www.sciencedirect.com
    HucMSCs can alleviate abnormal vasculogenesis induced by high glucose through the MAPK signaling pathway
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    sciencedirect.com/science/article/pii/S2589004224025793
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Microglia-derived ADAM9 promote GHRH neurons pyroptosis by Mad2L2-JNK-caspase-1 pathway in subarachnoid hemorrhage
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    pmc.ncbi.nlm.nih.gov/articles/PMC11575213/
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    A PROTAC degrader suppresses oncogenic functions of PTK6 inducing apoptosis of breast cancer cells
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    sciencedirect.com/science/article/pii/S2451945624004434
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Insulin Mediates Lipopolysaccharide-Induced Inflammatory Responses and Oxidative Stress in BV2 Microglia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11539848/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neurons enhance blood–brain barrier function via upregulating claudin-5 and VE-cadherin expression due to glial cell line-derived neurotrophic factor secretion
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    pmc.ncbi.nlm.nih.gov/articles/PMC11524583/
  36. Sep 2024
  37. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15169
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hesperetin but not ellagic acid increases myosin heavy chain expression and cell fusion in C2C12 myoblasts in the presence of oxidative stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC11402829/
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    Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma
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  40. Aug 2024
  41. www.sciencedirect.com www.sciencedirect.com
    MOF-mediated PRDX1 acetylation regulates inflammatory macrophage activation
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  42. Jul 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apocynin Prevents Cigarette Smoke-Induced Anxiety-Like Behavior and Preserves Microglial Profiles in Male Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11274253/
  44. Jun 2024
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 envelope protein regulates innate immune tolerance
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    Metallo-protease Peptidase M84 from Bacillus altitudinis induces ROS-dependent apoptosis in ovarian cancer cells by targeting PAR-1
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  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC11140209/
  48. May 2024
  49. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Monocarboxylate transporter 4 deficiency enhances high-intensity interval training-induced metabolic adaptations in skeletal muscle
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP285719
  50. 52.53.155.43 52.53.155.43
    TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis
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    52.53.155.43/86d6d1effc82110b06a7585d839c944adff76cc8/preprints202402.1027.v1-html.html
  51. www.biorxiv.org www.biorxiv.org
    Neurons enhance blood-brain barrier function via upregulating claudin-5 and VE-cadherin expression due to GDNF secretion
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    biorxiv.org/content/10.1101/2024.02.07.579396v1
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16356
  53. Apr 2024
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tgif1-deficiency impairs cytoskeletal architecture in osteoblasts by activating PAK3 signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11045221/
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    Turnover of PPP1R15A mRNA encoding GADD34 controls responsiveness and adaptation to cellular stress
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    sciencedirect.com/science/article/pii/S2211124724003978
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIM2 Selectively Regulates Inflammation-Driven Pathological Angiogenesis without Affecting Physiological Hypoxia-Mediated Angiogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10970352/
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    Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome
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    sciencedirect.com/science/article/pii/S209012322400119X
  58. Mar 2024
  59. 52.53.155.43 52.53.155.43
    Human seminal extracellular vesicles enhance endometrial receptivity through leukemia inhibitory factor
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    52.53.155.43/ef706d7fedeb9d14a9f80c03d77786b7f4c289d6/bqae035-html.html
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10944492/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer's and related dementias
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    ncbi.nlm.nih.gov/pmc/articles/PMC10933458/
  62. Feb 2024
  63. www.sciencedirect.com www.sciencedirect.com
    Gut microbial co-metabolite 2-methylbutyrylcarnitine exacerbates thrombosis via binding to and activating integrin α2β1
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    sciencedirect.com/science/article/abs/pii/S1550413124000147
  64. www.embopress.org www.embopress.org
    Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer’s and related dementias
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    embopress.org/doi/10.1038/s44319-024-00077-x
  65. www.sciencedirect.com www.sciencedirect.com
    Hepatocyte CHRNA4 mediates the MASH-promotive effects of immune cell-produced acetylcholine and smoking exposure in mice and humans
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    sciencedirect.com/science/article/pii/S1550413123004126
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OVOL2 induces autophagy-mediated epithelial-mesenchymal transition by the ERK1/2 MAPK signaling in lung adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10838806/
  67. Jan 2024
  68. www.sciencedirect.com www.sciencedirect.com
    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
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    sciencedirect.com/science/article/pii/S2666379123006171
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    O6-Methylguanine DNA Methyltransferase Regulates β-glucan-induced Trained Immunity of Macrophages via Farnesoid X Receptor and AMPK
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    ncbi.nlm.nih.gov/pmc/articles/PMC10792243/
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    Selective induction of human renal interstitial progenitor-like cell lineages from iPSCs reveals development of mesangial and EPO-producing cells
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    sciencedirect.com/science/article/pii/S2211124723016145
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    Metformin inhibits cell proliferation and ACTH secretion in AtT20 cells via regulating the MAPK pathway
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    sciencedirect.com/science/article/pii/S0303720723002915
  72. Nov 2023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-κB pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC10675918/
  74. www.sciencedirect.com www.sciencedirect.com
    Functional and spatial proteomics profiling reveals intra- and intercellular signaling crosstalk in colorectal cancer
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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ANKRD49 promotes the metastasis of NSCLC via activating JNK-ATF2/c-Jun-MMP-2/9 axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10644579/
  76. Oct 2023
  77. www.cell.com www.cell.com
    CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression
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    cell.com/cell-metabolism/fulltext/S1550-4131(23)00368-6
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of the JNK/COX-2/HIF-1α axis promotes M1 macrophage via glycolytic shift in HIV-1 infection
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    ncbi.nlm.nih.gov/pmc/articles/PMC10556724/
  79. aiche.onlinelibrary.wiley.com aiche.onlinelibrary.wiley.com
    Mechanochemical coupling of MGF mediates periodontal regeneration
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    aiche.onlinelibrary.wiley.com/doi/10.1002/btm2.10603
  80. www.cell.com www.cell.com
    The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation
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    cell.com/cell-reports/abstract/S2211-1247(23)01092-6
  81. Sep 2023
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    URAT1 is expressed in cardiomyocytes and dotinurad attenuates the development of diet-induced metabolic heart disease.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10483053/
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    CGK733 alleviates ovariectomy-induced bone loss through blocking RANKL-mediated Ca2+ oscillations and NF-κB/MAPK signaling pathways
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    sciencedirect.com/science/article/pii/S2589004223018370
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucose Transporter-2 Regulation of Male versus Female Hypothalamic Astrocyte MAPK Expression and Activation: Impact of Glucose
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    ncbi.nlm.nih.gov/pmc/articles/PMC10361449/
  85. Aug 2023
  86. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Yang-html.html
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    52.53.155.43/ebaf450bc55b2dfbcc4f1c7a194e3583ce7f4fc5/British J Pharmacology - 2023 - Yang-html.html
  87. Jul 2023
  88. www.sciencedirect.com www.sciencedirect.com
    Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia
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    sciencedirect.com/science/article/pii/S221112472300880X
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    Caffeoylquinic acids isolated from Lonicera japonica Thunb. as TAK1 inhibitors protects against LPS plus IFN-γ-stimulated inflammation by interacting with KEAP1-regulated NRF2 activation
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    sciencedirect.com/science/article/pii/S0753332223008284
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    Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin
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    sciencedirect.com/science/article/pii/S1074761323002637
  91. Jun 2023
  92. www.mdpi.com www.mdpi.com
    Effects of Dietary Oleacein Treatment on Endothelial Dysfunction and Lupus Nephritis in Balb/C Pristane-Induced Mice
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    mdpi.com/2076-3921/12/6/1303
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    Identification of an IL-1 receptor mutation driving autoinflammation directs IL-1-targeted drug design
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    sciencedirect.com/science/article/pii/S1074761323002315
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    Acetate controls endothelial-to-mesenchymal transition
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    UBE2M-mediated neddylation of TRIM21 regulates obesity-induced inflammation and metabolic disorders
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    SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury
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  97. www.cell.com www.cell.com
    Secreted Akkermansia muciniphila threonyl-tRNA synthetase functions to monitor and modulate immune homeostasis
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    cell.com/cell-host-microbe/fulltext/S1931-3128(23)00200-7
  98. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16080
  99. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Targeting formyl peptide receptor 1 by anteiso-C13-surfactin for neutrophil-dominant acute respiratory distress syndrome
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16073
  100. May 2023
  101. www.sciencedirect.com www.sciencedirect.com
    Heat promotes melanogenesis by increasing the paracrine effects in keratinocytes via the TRPV3/Ca2+/Hh signaling pathway
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Overexpression of mitogen-activated protein kinase... : Neural Regeneration Research
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    ncbi.nlm.nih.gov/pmc/articles/PMC10154501/
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BACE1 regulates expression of Clusterin in astrocytes for enhancing clearance of β-amyloid peptides
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    ncbi.nlm.nih.gov/pmc/articles/PMC10161466/
  104. www.sciencedirect.com www.sciencedirect.com
    The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
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    sciencedirect.com/science/article/pii/S235239642200336X
  105. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The E3 Ligase TRIM4 Facilitates SET Ubiquitin-Mediated Degradation to Enhance ER-α Action in Breast Cancer
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    onlinelibrary.wiley.com/doi/10.1002/advs.202201701
  106. Apr 2023
  107. www.biorxiv.org www.biorxiv.org
    ANKRD49 promotes the metastasis of NCI-H1299 and NCI-H1703 cells via activating JNK-ATF2/c-Jun-MMP-2/9 axis
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    biorxiv.org/content/10.1101/2023.03.22.533821v1
  108. www.sciencedirect.com www.sciencedirect.com
    LBP1C-2 from Lycium barbarum maintains skeletal muscle satellite cell pool by interaction with FGFR1
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  109. www.sciencedirect.com www.sciencedirect.com
    Identification of a comprehensive alternative splicing function during epithelial-mesenchymal transition
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