44 Matching Annotations
  1. May 2024
  2. www.sciencedirect.com www.sciencedirect.com
    A RIPK1-specific PROTAC degrader achieves potent antitumor activity by enhancing immunogenic cell death
    1
    1. scibot 24 May 2024
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      DOI: 10.1016/j.immuni.2024.04.025

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    sciencedirect.com/science/article/pii/S1074761324002309
  3. www.mdpi.com www.mdpi.com
    IL17A Suppresses IGFBP1 in Human Endometrial Stromal Cells
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    1. scibot 03 May 2024
      RRID:AB_11024092

      DOI: 10.3390/reprodmed5020006

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    mdpi.com/2673-3897/5/2/6
  4. www.sciencedirect.com www.sciencedirect.com
    N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation
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    1. scibot 02 May 2024
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      DOI: 10.1016/j.immuni.2024.04.004

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    sciencedirect.com/science/article/pii/S1074761324002097
  5. Mar 2024
  6. link.springer.com link.springer.com
    Edaravone dexborneol promotes M2 microglia polarization against lipopolysaccharide-induced inflammation via suppressing TLR4/MyD88/NF-κB pathway
    1
    1. scibot 20 Mar 2024
      RRID:AB_11024092

      DOI: 10.1007/s00210-024-03045-3

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    link.springer.com/article/10.1007/s00210-024-03045-3
  7. Feb 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
    1
    1. scibot 06 Feb 2024
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      DOI: 10.1158/2159-8290.CD-22-1401

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    ncbi.nlm.nih.gov/pmc/articles/PMC10524254/
  9. Jan 2024
  10. www.sciencedirect.com www.sciencedirect.com
    CHCHD4-TRIAP1 regulation of innate immune signaling mediates skeletal muscle adaptation to exercise
    1
    1. scibot 07 Jan 2024
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      DOI: 10.1016/j.celrep.2023.113626

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    sciencedirect.com/science/article/pii/S2211124723016376
  11. Nov 2023
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins
    2
    1. scibot 11 Nov 2023
      AB_11024092

      DOI: 10.1097/BS9.0000000000000168

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      AB_11024092

      DOI: 10.1097/BS9.0000000000000168

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    ncbi.nlm.nih.gov/pmc/articles/PMC10629731/
  13. Oct 2023
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-Psychoactive Phytocannabinoids Inhibit Inflammation-Related Changes of Human Coronary Artery Smooth Muscle and Endothelial Cells
    1
    1. scibot 18 Oct 2023
      RRID:AB_11024092

      DOI: 10.3390/cells12192389

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    ncbi.nlm.nih.gov/pmc/articles/PMC10571842/
  15. www.cell.com www.cell.com
    15-keto-PGE2 Alleviates Nonalcoholic Steatohepatitis through its Covalent Modification of NF-κB Factors
    1
    1. scibot 06 Oct 2023
      RRID:AB_11024092

      DOI: 10.1016/j.isci.2023.107997

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    cell.com/iscience/abstract/S2589-0042(23)02074-6
  16. Aug 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IRP1 Mediated Ferroptosis Reverses Temozolomide Resistance in Glioblastoma via Affecting LCN2/FPN1 Signaling Axis Depended on NFKB2
    1
    1. scibot 01 Aug 2023
      RRID:AB_11024092

      DOI: 10.1016/j.isci.2023.107377

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    ncbi.nlm.nih.gov/pmc/articles/PMC10374607/
  18. Jun 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Sublethal necroptosis signaling promotes inflammation and liver cancer
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.immuni.2023.05.017

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    sciencedirect.com/science/article/pii/S1074761323002340
  20. Apr 2023
  21. www.sciencedirect.com www.sciencedirect.com
    Combating breast cancer progression through combination therapy with hypomethylating agent and glucocorticoid
    1
    1. scibot 21 Apr 2023
      RRID:AB_11024092

      DOI: 10.1016/j.isci.2023.106597

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    sciencedirect.com/science/article/pii/S2589004223006740
  22. www.sciencedirect.com www.sciencedirect.com
    PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1
    1
    1. scibot 08 Apr 2023
      RRID:AB_11024092

      DOI: 10.1016/j.celrep.2023.112340

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    sciencedirect.com/science/article/pii/S2211124723003510
  23. Feb 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise
    1
    1. scibot 23 Feb 2023
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      DOI: 10.1016/j.cmet.2023.01.011

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    sciencedirect.com/science/article/pii/S1550413123000116
  25. Jan 2023
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice
    1
    1. scibot 06 Jan 2023
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      DOI: 10.1016/j.isci.2022.105769

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    ncbi.nlm.nih.gov/pmc/articles/PMC9804112/
  27. Nov 2022
  28. www.science.org www.science.org
    Caspase-8 inactivation drives autophagy-dependent inflammasome activation in myeloid cells
    1
    1. scibot 15 Nov 2022
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      DOI: 10.1126/sciadv.abn9912

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    science.org/doi/10.1126/sciadv.abn9912
  29. Oct 2022
  30. www.sciencedirect.com www.sciencedirect.com
    Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation
    1
    1. scibot 26 Oct 2022
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      DOI: 10.1016/j.chembiol.2022.10.002

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    sciencedirect.com/science/article/pii/S2451945622003567
  31. May 2022
  32. www.nature.com www.nature.com
    Effects of interleukin 1β on long noncoding RNA and mRNA expression profiles of human synovial fluid derived mesenchymal stem cells
    1
    1. scibot 21 May 2022
      RRID:AB_11024092

      DOI: 10.1038/s41598-022-12190-9

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    nature.com/articles/s41598-022-12190-9
  33. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
    1
    1. scibot 05 May 2022
      RRID:AB_11024092

      DOI: 10.1016/j.cell.2022.04.014

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    cell.com/cell/fulltext/S0092-8674(22)00461-5
  34. Mar 2022
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SHP2 allosteric inhibitor TK-453 alleviates psoriasis-like skin inflammation in mice via inhibition of IL-23/Th17 axis
    1
    1. scibot 23 Mar 2022
      RRID:AB_11024092

      DOI: 10.1016/j.isci.2022.104009

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    ncbi.nlm.nih.gov/pmc/articles/PMC8927994/
  36. Jan 2022
  37. www.sciencedirect.com www.sciencedirect.com
    Self-developed NF-κB inhibitor 270 protects against LPS-induced acute kidney injury and lung injury through improving inflammation
    1
    1. scibot 11 Jan 2022
      #8943

      DOI: 10.1016/j.biopha.2022.112615

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    sciencedirect.com/science/article/pii/S0753332222000038
  38. www.sciencedirect.com www.sciencedirect.com
    Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses
    1
    1. scibot 11 Jan 2022
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      DOI: 10.1016/j.molcel.2021.12.006

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    sciencedirect.com/science/article/pii/S1097276521010686
  39. Dec 2021
  40. www.nature.com www.nature.com
    A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
    1
    1. scibot 21 Dec 2021
      RRID:AB_11024092

      DOI: 10.1038/s41467-021-27452-9

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    nature.com/articles/s41467-021-27452-9
  41. Aug 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 01 Aug 2021
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      DOI: 10.1016/j.celrep.2018.11.048

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    sciencedirect.com/science/article/pii/S2211124718318114
  43. Jul 2021
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Curcumin attenuates proangiogenic and proinflammatory factors in human eutopic endometrial stromal cells through the NF‐κB signaling pathway
    1
    1. scibot 31 Jul 2021
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      DOI: 10.1002/jcp.27360

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    ncbi.nlm.nih.gov/pmc/articles/PMC6344303/
  45. www.sciencedirect.com www.sciencedirect.com
    Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell
    1
    1. scibot 07 Jul 2021
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      DOI: 10.1016/j.celrep.2021.109364

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    sciencedirect.com/science/article/pii/S2211124721007622
  46. May 2021
  47. www.sciencedirect.com www.sciencedirect.com
    The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation
    1
    1. scibot 26 May 2021
      RRID:AB_11024092

      DOI: 10.1016/j.immuni.2021.04.027

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    sciencedirect.com/science/article/pii/S1074761321001898
  48. www.sciencedirect.com www.sciencedirect.com
    N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation
    1
    1. scibot 05 May 2021
      RRID:AB_11024092

      DOI: 10.1016/j.devcel.2020.10.023

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    sciencedirect.com/science/article/pii/S1534580720308431
  49. Feb 2021
  50. www.cell.com www.cell.com
    Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies
    1
    1. scibot 27 Feb 2021
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      DOI: 10.1016/j.ccell.2020.08.001

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    cell.com/cancer-cell/abstract/S1535-6108(20)30375-5
  51. Jan 2021
  52. link.springer.com link.springer.com
    The inflammatory kinase IKKα phosphorylates and stabilizes c-Myc and enhances its activity
    1
    1. scibot 21 Jan 2021
      RRID:AB_11024092

      DOI: 10.1186/s12943-021-01308-8

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    link.springer.com/article/10.1186/s12943-021-01308-8
  53. Sep 2020
  54. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    BCR-Induced Ca2+ Signals Dynamically Tune Survival, Metabolic Reprogramming, and Proliferation of Naive B Cells
    1
    1. scibot 17 Sep 2020
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      DOI: 10.1016/j.celrep.2020.03.038

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    pubmed.ncbi.nlm.nih.gov/32294437/
  55. www.sciencedirect.com www.sciencedirect.com
    Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis
    1
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      DOI: 10.1016/j.celrep.2020.107990

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    sciencedirect.com/science/article/pii/S221112472030975X
  56. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 16 Sep 2020
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      DOI: 10.1111/bph.14972

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14972
  57. www.sciencedirect.com www.sciencedirect.com
    Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells
    1
    1. scibot 13 Sep 2020
      RRID:AB_11024092

      DOI: 10.1016/j.celrep.2020.03.029

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    sciencedirect.com/science/article/pii/S2211124720303430
  58. Jan 2020
  59. www.sciencedirect.com www.sciencedirect.com
    TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL
    1
    1. scibot 13 Jan 2020
      RRID:AB_11024092

      DOI: 10.1016/j.molcel.2019.05.022

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    sciencedirect.com/science/article/pii/S1097276519303946
  60. www.sciencedirect.com www.sciencedirect.com
    α-Ketoglutarate-Activated NF-κB Signaling Promotes Compensatory Glucose Uptake and Brain Tumor Development
    1
    1. scibot 13 Jan 2020
      RRID:AB_11024092

      DOI: 10.1016/j.molcel.2019.07.007

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    sciencedirect.com/science/article/pii/S1097276519305374
  61. Nov 2018
  62. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    1. scibot 05 Nov 2018
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    onlinelibrary.wiley.com/doi/full/10.1002/jcp.27360
  63. www.sciencedirect.com www.sciencedirect.com
    TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging
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    sciencedirect.com/science/article/pii/S0092867418309693
  64. www.sciencedirect.com www.sciencedirect.com
    Human Cytomegalovirus Protein UL31 Inhibits DNA Sensing of cGAS to Mediate Immune Evasion
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      RRID:AB_11024092
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    sciencedirect.com/science/article/pii/S1931312818302610
  65. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Antagonizing peroxisome proliferator‐activated receptor γ facilitates M1‐to‐M2 shift of microglia by enhancing autophagy via the LKB1–AMPK signaling pathway
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    1. scibot 05 Nov 2018
      RRID:AB_11024092

      Curator: @anp055

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      RRID:AB_11024092 RRIDCUR:Validated
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    onlinelibrary.wiley.com/doi/full/10.1111/acel.12774
  66. www.sciencedirect.com www.sciencedirect.com
    Vitamin D Switches BAF Complexes to Protect β Cells
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    1. scibot 05 Nov 2018
      RRID:AB_11024092

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      (Cell Signaling Technology Cat# 8943, RRID:AB_11024092)

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    sciencedirect.com/science/article/pii/S0092867418305063
  67. www.sciencedirect.com www.sciencedirect.com
    B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells
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    1. scibot 05 Nov 2018
      RRID:AB_11024092

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      (Cell Signaling Technology Cat# 8943, RRID:AB_11024092)

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      RRID:AB_11024092
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    sciencedirect.com/science/article/pii/S1074761318300293
  68. www.sciencedirect.com www.sciencedirect.com
    Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation
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    1. scibot 05 Nov 2018
      RRID:AB_11024092

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      (Cell Signaling Technology Cat# 8943, RRID:AB_11024092)

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      RRID:AB_11024092
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    sciencedirect.com/science/article/pii/S1931312818301331