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IDO1 methylation by EZH2 confers resistance to its targeted therapy in colorectal cancer through tryptophan-kynurenine metabolic rewiring

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1. scibot 07 Nov 2026
  
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  DOI: 10.1016/j.celrep.2026.118237
  
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sciencedirect.com/science/article/pii/S2211124726013161
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A competitive PDLIM1-USP14 axis destabilizes ACTN4 to disturb the invasive homeostasis of trophoblast in preeclampsia

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1. scibot 05 Nov 2026
  
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  DOI: 10.1016/j.celrep.2026.118211
  
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sciencedirect.com/science/article/pii/S2211124726012908
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Stress hyperglycemia impairs FOXK2-dependent macrophage cardiac repair after myocardial infarction

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1. scibot 05 Nov 2026
  
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  DOI: 10.1016/j.celrep.2026.118203
  
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sciencedirect.com/science/article/pii/S2211124726012829
Jul 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FAM134B-mediated ER-phagy degrades APP and suppresses Alzheimer’s disease pathology

1
1. scibot 08 Jul 2026
  
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  DOI: 10.1038/s44318-026-00818-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13324857/
Jun 2026
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Lactylation Converts ABHD6 into a Mitochondrial Regulator That Drives Lenvatinib Resistance in Hepatocellular Carcinoma

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1. scibot 17 Jun 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-4282
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13266342/
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P5CS represses tumor progression via inhibiting assembly of 48S pre-translation initiation complex

1
1. scibot 17 Jun 2026
  
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  DOI: 10.1016/j.devcel.2026.05.011
  
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sciencedirect.com/science/article/pii/S1534580726001954
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Deacetylated PCBP1 licenses PARP1 activity for DNA damage repair

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1. scibot 04 Jun 2026
  
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  DOI: 10.1016/j.molcel.2026.05.008
  
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sciencedirect.com/science/article/pii/S109727652600314X
Jan 2026
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Endometrial stromal cell-derived TMAO sustains decidualization to prevent recurrent spontaneous abortion

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.cmet.2025.11.014
  
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sciencedirect.com/science/article/pii/S1550413125005285
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B cells disrupt tertiary lymphoid structure formation and suppress anti-tumor immunity

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.ccell.2025.12.011
  
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sciencedirect.com/science/article/pii/S1535610825005458
Dec 2025
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A gut-secreted histidine methyltransferase enforces cross-kingdom catalytic antifungal defense

1
1. scibot 18 Dec 2025
  
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  RRID:AB_11042316
  
  DOI: 10.1016/j.chom.2025.11.015
  
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sciencedirect.com:5037/science/article/pii/S1931312825004755
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TOM1 G307D variant impairs interaction with TOLLIP, autophagosome-lysosome fusion and regulation of innate immunity

1
1. scibot 16 Oct 2025
  
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  RRID:AB_11042316
  
  DOI: 10.1242/dmm.052140
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12519566/
Jul 2025
www.cell.com www.cell.com

TBK1 phagosomal recruitment enhances antifungal immunity via positive feedback regulation with SRC

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.celrep.2025.115972
  
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cell.com/cell-reports/abstract/S2211-1247(25)00743-0
Mar 2025
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Macrophage-specific PHGDH protects against MAFLD by suppressing TAK1

1
1. scibot 20 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115426
  
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sciencedirect.com/science/article/pii/S2211124725001974
Feb 2025
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STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma

1
1. scibot 11 Feb 2025
  
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  DOI: 10.1016/j.devcel.2025.01.014
  
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sciencedirect.com/science/article/pii/S1534580725000346
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Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3

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1. scibot 04 Feb 2025
  
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  DOI: 10.1016/j.celrep.2025.115250
  
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sciencedirect.com/science/article/pii/S221112472500021X
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Sirtuin 1/sirtuin 3 are robust lysine delactylases and sirtuin 1-mediated delactylation regulates glycolysis

1
1. scibot 05 Oct 2024
  
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  DOI: 10.1016/j.isci.2024.110911
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11440250/
May 2024
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Protocol for identifying OXCT1-mediated LACTB succinylation sites in vitro

1
1. scibot 30 May 2024
  
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  RRID:AB_11042316
  
  DOI: 10.1016/j.xpro.2024.103088
  
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sciencedirect.com/science/article/pii/S2666166724002533
Mar 2024
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PDGFRα+ITGA11+ fibroblasts foster early-stage cancer lymphovascular invasion and lymphatic metastasis via ITGA11-SELE interplay

2
1. scibot 01 Mar 2024
  
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  DOI: 10.1016/j.ccell.2024.02.002
  
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2. scibot 01 Mar 2024
  
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  DOI: 10.1016/j.ccell.2024.02.002
  
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sciencedirect.com/science/article/pii/S1535610824000461
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men

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1. scibot 03 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.108858
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10830871/
Jan 2024
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OXCT1 functions as a succinyltransferase, contributing to hepatocellular carcinoma via succinylating LACTB

1
1. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.molcel.2023.11.042
  
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sciencedirect.com/science/article/pii/S1097276523010195
Nov 2023
www.embopress.org www.embopress.org

MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression

1
1. scibot 03 Nov 2023
  
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  DOI: 10.15252/embj.2023114558
  
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embopress.org/doi/full/10.15252/embj.2023114558
May 2023
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MTHFD2 reprograms macrophage polarization by inhibiting PTEN

1
1. scibot 11 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112481
  
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sciencedirect.com/science/article/pii/S2211124723004928
Apr 2023
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CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth

1
1. scibot 06 Apr 2023
  
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  DOI: 10.1016/j.celrep.2023.112316
  
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sciencedirect.com/science/article/pii/S2211124723003273
Mar 2023
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Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS

1
1. scibot 28 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112309
  
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sciencedirect.com/science/article/pii/S2211124723003200
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Fam72a functions as a cell-cycle-controlled gene during proliferation and antagonizes apoptosis through reprogramming PP2A substrates

1
1. scibot 03 Mar 2023
  
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  DOI: 10.1016/j.devcel.2023.02.006
  
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sciencedirect.com/science/article/pii/S1534580723000485
Oct 2022
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Cytoplasmic SIRT6-mediated ACSL5 deacetylation impedes nonalcoholic fatty liver disease by facilitating hepatic fatty acid oxidation

1
1. scibot 09 Oct 2022
  
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  DOI: 10.1016/j.molcel.2022.09.018
  
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sciencedirect.com/science/article/pii/S1097276522009078
Dec 2020
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Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions

1
1. scibot 23 Dec 2020
  
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  RRID:AB_1104231
  
  DOI: 10.1016/j.celrep.2020.108538
  
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  Curator: @Naa003
  
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  RRID:AB_11042316 RRIDCUR:Unresolved RRIDCUR:Incorrect
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sciencedirect.com/science/article/pii/S2211124720315278
Jan 2020
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An Oxygen-Dependent Interaction between FBXL5 and the CIA-Targeting Complex Regulates Iron Homeostasis

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.molcel.2019.05.020
  
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  RRID:AB_11042316 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276519303922
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Type-I-IFN-Stimulated Gene TRIM5γ Inhibits HBV Replication by Promoting HBx Degradation

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.11.041
  
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  RRID:AB_11042316 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719315232
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Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.immuni.2019.11.015
  
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  RRID:AB_11042316 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1074761319304960
Nov 2017
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FGF13 Selectively Regulates Heat Nociception by Interacting with Nav1.7

1
1. scibot 08 Nov 2017
  
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  AB_11042316
  
  Curator: @Zeljana_Babic
  
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  RRID:AB_11042316 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0896627317300338