86 Matching Annotations
  1. Jun 2024
  2. www.nature.com www.nature.com
    A single infusion of engineered long-lived and multifunctional T cells confers durable remission of asthma in mice
    1
    1. scibot 06 Jun 2024
      RRID:AB_1107624

      DOI: 10.1038/s41590-024-01834-9

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    nature.com/articles/s41590-024-01834-9
  3. May 2024
  4. www.sciencedirect.com www.sciencedirect.com
    T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells
    1
    1. scibot 23 May 2024
      RRID:AB_1107624

      DOI: 10.1016/j.celrep.2024.114258

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    sciencedirect.com/science/article/pii/S2211124724005862
  5. www.sciencedirect.com www.sciencedirect.com
    One-carbon unit supplementation fuels purine synthesis in tumor-infiltrating T cells and augments checkpoint blockade
    1
    1. scibot 17 May 2024
      RRID:AB_1107624

      DOI: 10.1016/j.chembiol.2024.04.007

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    sciencedirect.com/science/article/pii/S2451945624001697
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect
    1
    1. scibot 15 May 2024
      RRID:AB_1107624

      DOI: 10.1084/jem.20221122

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    ncbi.nlm.nih.gov/pmc/articles/PMC11082451/
  7. www.sciencedirect.com www.sciencedirect.com
    Chemoradiotherapy-induced ACKR2+ tumor cells drive CD8+ T cell senescence and cervical cancer recurrence
    1
    1. scibot 09 May 2024
      RRID:AB_1107624

      DOI: 10.1016/j.xcrm.2024.101550

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    sciencedirect.com/science/article/pii/S2666379124002428
  8. www.sciencedirect.com www.sciencedirect.com
    A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification
    1
    1. scibot 02 May 2024
      RRID:AB_1107624

      DOI: 10.1016/j.immuni.2024.04.007

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    sciencedirect.com/science/article/pii/S1074761324002127
  9. Apr 2024
  10. www.sciencedirect.com www.sciencedirect.com
    25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages
    1
    1. scibot 19 Apr 2024
      BioXcellCat# BE0015

      DOI: 10.1016/j.immuni.2024.03.021

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    sciencedirect.com/science/article/pii/S1074761324001420
  11. Feb 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Sensory nerve release of CGRP increases tumor growth in HNSCC by suppressing TILs
    1
    1. scibot 29 Feb 2024
      BioXCellCat# BE0015-1

      DOI: 10.1016/j.medj.2024.02.002

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    sciencedirect.com/science/article/pii/S2666634024000746
  13. www.sciencedirect.com www.sciencedirect.com
    The CD27/CD70 pathway negatively regulates visceral adipose tissue-resident Th2 cells and controls metabolic homeostasis
    1
    1. scibot 22 Feb 2024
      RRID:AB_1107624

      DOI: 10.1016/j.celrep.2024.113824

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    sciencedirect.com/science/article/pii/S2211124724001529
  14. Jan 2024
  15. dx.doi.org dx.doi.org
    Formate supplementation enhances anti-tumor CD8+ T cell fitness and efficacy of PD-1 blockade
    1
    1. scibot 11 Jan 2024
      RRID:AB_1107624

      DOI: 10.1158/2159-8290.CD-22-1301

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    dx.doi.org/10.1158/2159-8290.CD-22-1301
  16. Dec 2023
  17. 52.53.155.43 52.53.155.43
    cd-22-1301-html.html
    1
    1. scibot 01 Dec 2023
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      DOI: 10.1158/2159-8290.cd-22-1301

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    52.53.155.43/ed2c7eab61775ee4a9efbdfa91d6b4b18a13354a/cd-22-1301-html.html
  18. Nov 2023
  19. www.biorxiv.org www.biorxiv.org
    Induction of immortal-like and functional CAR-T cells by defined factors
    1
    1. scibot 17 Nov 2023
      RRID:AB_1107624

      DOI: 10.1101/2023.11.06.565785

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    biorxiv.org/content/10.1101/2023.11.06.565785v1
  20. www.biorxiv.org www.biorxiv.org
    One infusion of engineered long-lasting and multifunctional T cells cures asthma in mice
    1
    1. scibot 17 Nov 2023
      RRID:AB_1107624

      DOI: 10.1101/2023.11.06.565713

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    biorxiv.org/content/10.1101/2023.11.06.565713v1
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An essential role for miR-15/16 in Treg suppression and restriction of proliferation
    1
    1. scibot 02 Nov 2023
      RRID:AB_1107624

      DOI: 10.1016/j.celrep.2023.113298

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    ncbi.nlm.nih.gov/pmc/articles/PMC10664750/
  22. Oct 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation
    1
    1. scibot 28 Oct 2023
      RRID:AB_1107624

      DOI: 10.1016/j.celrep.2023.113323

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    sciencedirect.com/science/article/pii/S2211124723013359
  24. www.sciencedirect.com www.sciencedirect.com
    Progenitor-like exhausted SPRY1+CD8+ T cells potentiate responsiveness to neoadjuvant PD-1 blockade in esophageal squamous cell carcinoma
    1
    1. scibot 13 Oct 2023
      RRID:AB_1107624

      DOI: 10.1016/j.ccell.2023.09.011

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    sciencedirect.com/science/article/pii/S1535610823003276
  25. Aug 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Loss of CD4+ T cell-intrinsic arginase 1 accelerates Th1 response kinetics and reduces lung pathology during influenza infection
    1
    1. scibot 12 Aug 2023
      RRID:AB_1107624

      DOI: 10.1016/j.immuni.2023.07.014

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    sciencedirect.com/science/article/pii/S1074761323003278
  27. Jul 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Tumor aerobic glycolysis confers immune evasion through modulating sensitivity to T cell-mediated bystander killing via TNF-α
    1
    1. scibot 28 Jul 2023
      RRID:AB_1107624

      DOI: 10.1016/j.cmet.2023.07.001

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    sciencedirect.com/science/article/abs/pii/S1550413123002516
  29. www.sciencedirect.com www.sciencedirect.com
    Graded expression of the chemokine receptor CX3CR1 marks differentiation states of human and murine T cells and enables cross-species interpretation
    1
    1. scibot 27 Jul 2023
      RRID:AB_1107624

      DOI: 10.1016/j.immuni.2023.06.025

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    sciencedirect.com/science/article/pii/S1074761323002820
  30. www.sciencedirect.com www.sciencedirect.com
    Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity
    1
    1. scibot 07 Jul 2023
      AB_1107624

      DOI: 10.1016/j.cell.2023.06.002

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    sciencedirect.com/science/article/pii/S0092867423006426
  31. Mar 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut
    1
    1. scibot 16 Mar 2023
      RRID:AB_1107624

      DOI: 10.1016/j.immuni.2023.02.018

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    sciencedirect.com/science/article/pii/S1074761323000924
  33. www.sciencedirect.com www.sciencedirect.com
    Tissue-resident Lachnospiraceae family bacteria protect against colorectal carcinogenesis by promoting tumor immune surveillance
    1
    1. scibot 10 Mar 2023
      RRID:AB_1107624

      DOI: 10.1016/j.chom.2023.01.013

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    sciencedirect.com/science/article/pii/S1931312823000380
  34. Feb 2023
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell RNA sequencing reveals the suppressive effect of PPP1R15A inhibitor Sephin1 in antitumor immunity
    1
    1. scibot 01 Feb 2023
      RRID:AB_1107624

      DOI: 10.1016/j.isci.2023.105954

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    ncbi.nlm.nih.gov/pmc/articles/PMC9883195/
  36. Jan 2023
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    P2RX7 enhances tumor control by CD8+ T cells in adoptive cell therapy
    1
    1. scibot 06 Jan 2023
      RRID:AB_1107624

      DOI: 10.1158/2326-6066.CIR-21-0691

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    ncbi.nlm.nih.gov/pmc/articles/PMC9250641/
  38. Nov 2022
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiomics analysis couples mRNA turnover and translational control of glutamine metabolism to the differentiation of the activated CD4+ T cell
    1
    1. scibot 17 Nov 2022
      RRID:AB_1107624

      DOI: 10.1038/s41598-022-24132-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC9669047/
  40. www.researchsquare.com www.researchsquare.com
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    1
    1. scibot 11 Nov 2022
      RRID:AB_1107624

      DOI: 10.21203/rs.3.rs-658360/v1

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  41. Sep 2022
  42. www.sciencedirect.com www.sciencedirect.com
    Pak2-mediated phosphorylation promotes RORγt ubiquitination and inhibits colonic inflammation
    1
    1. scibot 15 Sep 2022
      RRID:AB_1107624

      DOI: 10.1016/j.celrep.2022.111345

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    sciencedirect.com/science/article/pii/S2211124722011731
  43. www.sciencedirect.com www.sciencedirect.com
    Balance between immunoregulatory B cells and plasma cells drives pancreatic tumor immunity
    1
    1. scibot 13 Sep 2022
      RRID:AB_1107624

      DOI: 10.1016/j.xcrm.2022.100744

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    sciencedirect.com/science/article/pii/S2666379122002932
  44. Aug 2022
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative Increase in T Regulatory Cells Enhances Bone Remodeling in Osteogenesis Imperfecta
    1
    1. scibot 27 Aug 2022
      RRID:AB_1107624

      DOI: 10.1016/j.isci.2022.104818

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    ncbi.nlm.nih.gov/pmc/articles/PMC9400089/
  46. www.sciencedirect.com www.sciencedirect.com
    Lung fibroblasts facilitate pre-metastatic niche formation by remodeling the local immune microenvironment
    1
    1. scibot 02 Aug 2022
      RRID:AB_1107624

      DOI: 10.1016/j.immuni.2022.07.001

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    sciencedirect.com/science/article/pii/S107476132200334X
  47. Jul 2022
  48. www.sciencedirect.com www.sciencedirect.com
    Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells
    1
    1. scibot 13 Jul 2022
      RRID:AB_1107624

      DOI: 10.1016/j.cmet.2022.06.008

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    sciencedirect.com/science/article/pii/S1550413122002285
  49. Jun 2022
  50. www.sciencedirect.com www.sciencedirect.com
    Neuropilin-1 cooperates with PD-1 in CD8+ T-cells predicting outcomes in melanoma patients treated with anti-PD1
    1
    1. scibot 17 Jun 2022
      RRID:AB_1107624

      DOI: 10.1016/j.isci.2022.104353

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    sciencedirect.com/science/article/pii/S2589004222006241
  51. aacrjournals.org aacrjournals.org
    Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function
    1
    1. scibot 01 Jun 2022
      RRID:AB_1107624

      DOI: 10.1158/0008-5472.CAN-21-3155

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    aacrjournals.org/cancerres/article/82/10/1969/696318/Carbon-Monoxide-Activates-PERK-Regulated-Autophagy
  52. Jan 2022
  53. www.nature.com www.nature.com
    Adenosine 2A receptor and TIM3 suppress cytolytic killing of tumor cells via cytoskeletal polarization
    1
    1. scibot 15 Jan 2022
      RRID:AB_1107624

      DOI: 10.1038/s42003-021-02972-8

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    nature.com/articles/s42003-021-02972-8
  54. Dec 2021
  55. www.sciencedirect.com www.sciencedirect.com
    Engagement of the costimulatory molecule ICOS in tissues promotes establishment of CD8+ tissue-resident memory T cells
    1
    1. scibot 21 Dec 2021
      RRID:AB_1107624

      DOI: 10.1016/j.immuni.2021.11.017

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    sciencedirect.com/science/article/pii/S1074761321005094
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation
    1
    1. scibot 08 Dec 2021
      RRID:AB_1107624

      DOI: 10.7554/eLife.70978

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    ncbi.nlm.nih.gov/pmc/articles/PMC8639145/
  57. Oct 2021
  58. www.sciencedirect.com www.sciencedirect.com
    Costimulation molecules differentially regulate the ERK-Zfp831 axis to shape T follicular helper cell differentiation
    1
    1. scibot 13 Oct 2021
      RRID:AB_1107624

      DOI: 10.1016/j.immuni.2021.09.018

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    sciencedirect.com/science/article/pii/S1074761321004039
  59. www.sciencedirect.com www.sciencedirect.com
    PI3Kδ coordinates transcriptional, chromatin, and metabolic changes to promote effector CD8+ T cells at the expense of central memory
    1
    1. scibot 13 Oct 2021
      RRID:AB_1107624

      DOI: 10.1016/j.celrep.2021.109804

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    sciencedirect.com/science/article/pii/S221112472101264X
  60. Aug 2021
  61. www.sciencedirect.com www.sciencedirect.com
    Delivery of membrane impermeable molecules to primary mouse T lymphocytes
    1
    1. scibot 18 Aug 2021
      RRID:AB_1107624

      DOI: 10.1016/j.xpro.2021.100757

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  62. www.jimmunol.org www.jimmunol.org
    MicroRNA-10a Negatively Regulates CD4+ T Cell IL-10 Production through Suppression of Blimp1
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      RRID:AB_1107624

      DOI: 10.4049/jimmunol.2100017

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  63. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.immuni.2018.09.013

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  64. Jul 2021
  65. www.sciencedirect.com www.sciencedirect.com
    The Transcription Factor Tox2 Drives T Follicular Helper Cell Development via Regulating Chromatin Accessibility
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      Anti-CD28 (clone 37.51)

      DOI: 10.1016/j.immuni.2019.10.006

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  66. Jun 2021
  67. www.sciencedirect.com www.sciencedirect.com
    Toll-like receptor 2 induces pathogenicity in Th17 cells and reveals a role for IPCEF in regulating Th17 cell migration
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      DOI: 10.1016/j.celrep.2021.109303

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  68. www.sciencedirect.com www.sciencedirect.com
    The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity
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  69. May 2021
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist
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      Anti-mouse CD28 (37.51) Syrian hamster monoclonal

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  71. www.sciencedirect.com www.sciencedirect.com
    Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses
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    Sensing of ATP via the Purinergic Receptor P2RX7 Promotes CD8+ Trm Cell Generation by Enhancing Their Sensitivity to the Cytokine TGF-β
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    Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response
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  74. Apr 2021
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    Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells
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    CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability
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    MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23
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    Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity
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  80. www.sciencedirect.com www.sciencedirect.com
    Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy
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    In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions
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    A distal Foxp3 enhancer enables interleukin-2 dependent thymic Treg cell lineage commitment for robust immune tolerance
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  83. Mar 2021
  84. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  85. www.sciencedirect.com www.sciencedirect.com
    Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity
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      DOI: 10.1016/j.celrep.2021.108833

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  86. Feb 2021
  87. www.sciencedirect.com www.sciencedirect.com
    The TGF-β superfamily cytokine Activin-A is induced during autoimmune neuroinflammation and drives pathogenic Th17 cell differentiation
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    sciencedirect.com/science/article/pii/S1074761320305380
  88. www.nature.com www.nature.com
    Metabolic conditioning of CD8 + effector T cells for adoptive cell therapy
    1
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      anti-CD28

      DOI: 10.1038/s42255-020-0256-z

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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity
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  90. Dec 2020
  91. www.sciencedirect.com www.sciencedirect.com
    Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis
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      RRID:AB_1107624

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  92. Sep 2020
  93. www.sciencedirect.com www.sciencedirect.com
    Serine Catabolism Feeds NADH when Respiration Is Impaired
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      RRID:AB_1107624

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  94. Jan 2020
  95. www.sciencedirect.com www.sciencedirect.com
    High Glucose Intake Exacerbates Autoimmunity through Reactive-Oxygen-Species-Mediated TGF-β Cytokine Activation
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  96. www.sciencedirect.com www.sciencedirect.com
    miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival
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      DOI: 10.1016/j.celrep.2019.07.064

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    Amino Acids License Kinase mTORC1 Activity and Treg Cell Function via Small G Proteins Rag and Rheb
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    Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease
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      DOI: 10.1016/j.cell.2019.11.026

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    A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation
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    Disrupting Myelin-Specific Th17 Cell Gut Homing Confers Protection in an Adoptive Transfer Experimental Autoimmune Encephalomyelitis
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    Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity
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  102. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
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  103. www.sciencedirect.com www.sciencedirect.com
    Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R−STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity
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    Natural Genetic Variation Reveals Key Features of Epigenetic and Transcriptional Memory in Virus-Specific CD8 T Cells
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      DOI: 10.1016/j.ebiom.2019.04.045

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      DOI: 10.1016/j.immuni.2019.01.003

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    sciencedirect.com/science/article/pii/S1074761319300032
  110. Nov 2018
  111. www.sciencedirect.com www.sciencedirect.com
    Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens
    1
    1. scibot 05 Nov 2018
      RRID:AB_1107624

      Curator: @Jmenke

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      (Bio X Cell Cat# BE0015-1, RRID:AB_1107624)

      SciCrunch record: RRID:AB_1107624

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      RRID:AB_1107624 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867418312340
  112. www.sciencedirect.com www.sciencedirect.com
    Blimp-1 Functions as a Molecular Switch to Prevent Inflammatory Activity in Foxp3+RORγt+ Regulatory T Cells
    1
    1. scibot 05 Nov 2018
      RRID:AB_1107624

      Curator: @evieth

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      (Bio X Cell Cat# BE0015-1, RRID:AB_1107624)

      SciCrunch record: RRID:AB_1107624

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      RRID:AB_1107624 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124718314463
  113. elifesciences.org elifesciences.org
    Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation
    1
    1. scibot 05 Nov 2018
      RRID:AB_1107624

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      (Bio X Cell Cat# BE0015-1, RRID:AB_1107624)

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      RRID:AB_1107624
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    elifesciences.org/articles/36158
  114. www.sciencedirect.com www.sciencedirect.com
    Iron Drives T Helper Cell Pathogenicity by Promoting RNA-Binding Protein PCBP1-Mediated Proinflammatory Cytokine Production
    1
    1. scibot 05 Nov 2018
      RRID:AB_1107624

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      (Bio X Cell Cat# BE0015-1, RRID:AB_1107624)

      SciCrunch record: RRID:AB_1107624

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      RRID:AB_1107624
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    sciencedirect.com/science/article/pii/S1074761318302449
  115. www.sciencedirect.com www.sciencedirect.com
    T Cell Receptor-Regulated TGF-β Type I Receptor Expression Determines T Cell Quiescence and Activation
    1
    1. scibot 05 Nov 2018
      BE0015-1

      Curator: @Jmenke

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      (Bio X Cell Cat# BE0015-1, RRID:AB_1107624)

      SciCrunch record: RRID:AB_1107624

      Alternate resolvers: SciCrunch xml N2T identifiers.org

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      RRID:AB_1107624 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1074761318301237
  116. www.sciencedirect.com www.sciencedirect.com
    Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism
    1
    1. scibot 05 Nov 2018
      RRID:AB_1107624

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      (Bio X Cell Cat# BE0015-1, RRID:AB_1107624)

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      RRID:AB_1107624
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    sciencedirect.com/science/article/pii/S1074761318301912
  117. www.sciencedirect.com www.sciencedirect.com
    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
    1
    1. scibot 05 Nov 2018
      RRID:AB_1107624

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      (Bio X Cell Cat# BE0015-1, RRID:AB_1107624)

      SciCrunch record: RRID:AB_1107624

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      RRID:AB_1107624
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    sciencedirect.com/science/article/pii/S1550413117306186
  118. Nov 2017
  119. www.sciencedirect.com www.sciencedirect.com
    Catch and Release of Cytokines Mediated by Tumor Phosphatidylserine Converts Transient Exposure into Long-Lived Inflammation
    1
    1. scibot 08 Nov 2017
      AB_1107624

      Curator: @Zeljana_Babic

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      (Bio X Cell Cat# BE0015-1, RRID:AB_1107624)

      SciCrunch record: RRID:AB_1107624

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      RRID:AB_1107624 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517303283