118 Matching Annotations
  1. Last 7 days
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    Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ
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    sciencedirect.com/science/article/pii/S1931312825002975
  3. Aug 2025
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    A RAS(ON) Multi-Selective Inhibitor Combination Therapy Triggers Long-term Tumor Control through Senescence-Associated Tumor-Immune Equilibrium in Pancreatic Ductal Adenocarcinoma
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  5. Jul 2025
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    Phosphoglycerate mutase regulates Treg differentiation through control of serine synthesis and one-carbon metabolism
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    Adoptively transferred Th17 cells cooperate with host B cells to achieve durable tumor immunity
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  8. Jun 2025
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    Maternal vitamin D regulates the metabolic rearrangement of offspring CD4+ T cells in response to intestinal inflammation
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    Fc-optimized anti-CTLA-4 antibodies increase tumor-associated high endothelial venules and sensitize refractory tumors to PD-1 blockade
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  11. May 2025
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    Trajectories of macrophage ontogeny and reprogramming in cancer
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    Bone metastases diminish extraosseous response to checkpoint blockade immunotherapy through osteopontin-producing osteoclasts
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    sciencedirect.com/science/article/pii/S1535610825001370
  14. Apr 2025
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    Systemic 4-1BB stimulation augments extrafollicular memory B cell formation and recall responses during Plasmodium infection
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  16. Feb 2025
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    Tumor cell–intrinsic Piezo2 drives radioresistance by impairing CD8+ T cell stemness maintenance
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    Dynamics of tissue repair regulatory T cells and damage in acute Trypanosoma cruzi infection
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  20. Jan 2025
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    Contrasting cytotoxic and regulatory T cell responses underlying distinct clinical outcomes to anti-PD-1 plus lenvatinib therapy in cancer
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  22. Nov 2024
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    Meningeal neutrophil immune signaling influences behavioral adaptation following threat
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    Tissue-colonizing disseminated tumor cells secrete prostaglandin E2 to promote NK cell dysfunction and evade anti-metastatic immunity
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    Probiotics and their metabolite spermidine enhance IFN-γ+CD4+ T cell immunity to inhibit hepatitis B virus
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  26. Aug 2024
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    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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    LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity
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    Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
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  30. May 2024
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    Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng
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    Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy
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    The histone lysine methyltransferase MLL1 regulates the activation and functional specialization of regulatory T cells
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    A CTCF-binding site in the Mdm1-Il22-Ifng locus shapes cytokine expression profiles and plays a critical role in early Th1 cell fate specification
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  35. Apr 2024
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    Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity
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    Regulation of T helper cell differentiation by the interplay between histone modification and chromatin interaction
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    Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection
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  39. Mar 2024
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    Clinical drug screening reveals clofazimine potentiates the efficacy while reducing the toxicity of anti-PD-1 and CTLA-4 immunotherapy
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    Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers
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  42. Feb 2024
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    The CD27/CD70 pathway negatively regulates visceral adipose tissue-resident Th2 cells and controls metabolic homeostasis
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  44. Jan 2024
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    Fc-fused IL-7 provides broad antiviral effects against respiratory virus infections through IL-17A-producing pulmonary innate-like T cells
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    Bispecific dendritic-T cell engager potentiates anti-tumor immunity
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  47. Dec 2023
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    More time to kill: a longer liver stage increases T cell-mediated protection against pre-erythrocytic malaria
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  49. Nov 2023
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    Mice with FVB-derived sequence on chromosome 17 succumb to disseminated virus infection due to aberrant NK cell and T cell responses
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    FASlpr gene dosage tunes the extent of lymphoproliferation and T cell differentiation in lupus
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  52. Oct 2023
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    Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease
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  54. Jul 2023
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    A surgically optimized intraoperative poly(I:C)-releasing hydrogel prevents cancer recurrence
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    A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity
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    Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity
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  58. Jun 2023
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    Quantitative control of Ets1 dosage by a multi-enhancer hub promotes Th1 cell differentiation and protects from allergic inflammation
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    RORψt+CD4+ T cells promote IL-23R-mediated neuronal cell apoptosis in the central nervous system
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    Natural killer cells and innate lymphoid cells 1 tune anxiety-like behavior and memory in mice via interferon-γ and acetylcholine
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  62. May 2023
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    Transcriptional and metabolic programs promote the expansion of follicular helper T cells in lupus-prone mice
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  64. Apr 2023
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    Restraint of IFN-γ expression through a distal silencer CNS–28 for tissue homeostasis
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    A neutrophil response linked to tumor control in immunotherapy
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  67. Mar 2023
  68. europepmc.org europepmc.org
    mRNAs encoding IL-12 and a decoy-resistant variant of IL-18 synergize to engineer T cells for efficacious intratumoral adoptive immunotherapy
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  69. Jan 2023
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    Type I interferon/STAT1 signaling regulates UBE2M-mediated antiviral innate immunity in a negative feedback manner
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    Opioid-induced fragile-like regulatory T cells contribute to withdrawal
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    GATA4 controls regionalization of tissue immunity and commensal-driven immunopathology
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    Bispecific PD1-IL2v and anti-PD-L1 break tumor immunity resistance by enhancing stem-like tumor-reactive CD8+ T cells and reprogramming macrophages
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    Immunoediting instructs tumor metabolic reprogramming to support immune evasion
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  75. Nov 2022
  76. www.cell.com www.cell.com
    Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop
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    cell.com/cancer-cell/fulltext/S1535-6108(22)00549-9
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    The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity
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  78. Sep 2022
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucose promotes regulatory T cell differentiation to maintain intestinal homeostasis
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    Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity
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    Inhibition of Th1 activation and differentiation by dietary guar gum ameliorates experimental autoimmune encephalomyelitis
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  82. Aug 2022
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    Faecalibaculum rodentium remodels retinoic acid signaling to govern eosinophil-dependent intestinal epithelial homeostasis
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  84. Jun 2022
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9841318/
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    Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function
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    aacrjournals.org/cancerres/article/82/10/1969/696318/Carbon-Monoxide-Activates-PERK-Regulated-Autophagy
  87. May 2022
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    Newly recruited intraepithelial Ly6A+CCR9+CD4+ T cells protect against enteric viral infection
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  89. Apr 2022
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    ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection
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  91. Mar 2022
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    Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites
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  93. Feb 2022
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    Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity
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    ncbi.nlm.nih.gov/pmc/articles/PMC8888129/
  95. Jan 2022
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    The enteric pathogen Cryptosporidium parvum exports proteins into the cytosol of the infected host cell
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    ncbi.nlm.nih.gov/pmc/articles/PMC8687662/
  97. Dec 2021
  98. elifesciences.org elifesciences.org
    IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-γ production by CD25+Foxp3- T cells
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    elifesciences.org/articles/62432
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    Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8639145/
  100. Nov 2021
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    Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade
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  102. Oct 2021
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    Cold exposure protects from neuroinflammation through immunologic reprogramming
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    Costimulation molecules differentially regulate the ERK-Zfp831 axis to shape T follicular helper cell differentiation
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    Synergistic effect of non-neutralizing antibodies and interferon-γ for cross-protection against influenza
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  106. Aug 2021
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    Delivery of membrane impermeable molecules to primary mouse T lymphocytes
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    MicroRNA-10a Negatively Regulates CD4+ T Cell IL-10 Production through Suppression of Blimp1
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    jimmunol.org/content/207/3/985
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    CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
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  112. Jul 2021
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    The Transcription Factor Tox2 Drives T Follicular Helper Cell Development via Regulating Chromatin Accessibility
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    A safe and effective mucosal RSV vaccine in mice consisting of RSV phosphoprotein and flagellin variant
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  118. May 2021
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    Pre-clinical evaluation of a whole-parasite vaccine to control human babesiosis
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    Food colorants metabolized by commensal bacteria promote colitis in mice with dysregulated expression of interleukin-23
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    Glycolytic ATP fuels phosphoinositide 3-kinase signaling to support effector T helper 17 cell responses
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    Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells
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    Group 1 innate lymphoid-cell-derived interferon-γ maintains anti-viral vigilance in the mucosal epithelium
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    The Conserved Non-coding Sequences CNS6 and CNS9 Control Cytokine-Induced Rorc Transcription during T Helper 17 Cell Differentiation
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