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Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-γ

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1. scibot 30 Aug 2025
  
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  DOI: 10.1016/j.chom.2025.08.001
  
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sciencedirect.com/science/article/pii/S1931312825002975
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Selective TLR ligand stimulation enhances in vivo mosquito-borne flavivirus pathogenicity

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1. scibot 30 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116210
  
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sciencedirect.com/science/article/pii/S2211124725009817
Aug 2025
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Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

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1. scibot 14 Aug 2025
  
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  DOI: 10.1126/sciadv.abf9141
  
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science.org/doi/10.1126/sciadv.abf9141
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CHI3L3+ immature neutrophils inhibit anti-tumor immunity and impede immune checkpoint blockade therapy in bone metastases

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1. scibot 08 Aug 2025
  
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  DOI: 10.1016/j.ccell.2025.07.007
  
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sciencedirect.com/science/article/pii/S1535610825003137
Jul 2025
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GPRC5A/CXCL8/NLRP3-mediated neutrophil extracellular traps drive gemcitabine-nab-paclitaxel resistance in pancreatic adenocarcinoma

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1. scibot 30 Jul 2025
  
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  DOI: 10.20892/j.issn.2095-3941.2025.0040
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12302273/
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TIM3+ breast cancer cells license immune evasion during micrometastasis outbreak

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.ccell.2025.06.015
  
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cell.com/cancer-cell/abstract/S1535-6108(25)00265-X
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APOE protects against severe infection with Mycobacterium tuberculosis by restraining production of neutrophil extracellular traps

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1. scibot 02 Jul 2025
  
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  DOI: 10.1371/journal.ppat.1013267
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12201663/
Jun 2025
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A CXCR4 partial agonist improves immunotherapy by targeting immunosuppressive neutrophils and cancer-driven granulopoiesis

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1. scibot 28 Jun 2025
  
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  DOI: 10.1016/j.ccell.2025.06.006
  
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sciencedirect.com/science/article/pii/S1535610825002569
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Chalkophore-mediated respiratory oxidase flexibility controls M. tuberculosis virulence

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1. scibot 12 Jun 2025
  
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  DOI: 10.7554/eLife.105794
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12140626/
May 2025
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PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma

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1. scibot 28 May 2025
  
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  DOI: 10.1158/2767-9764.CRC-24-0571
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12099492/
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Activation of the endoplasmic reticulum stress regulator IRE1α compromises pulmonary host defenses

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115632
  
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sciencedirect.com/science/article/pii/S2211124725004036
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Understanding and reversing mammary tumor-driven reprogramming of myelopoiesis to reduce metastatic spread

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.ccell.2025.04.007
  
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sciencedirect.com/science/article/pii/S1535610825001667
Apr 2025
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A type 1 immune-stromal cell network mediates disease tolerance against intestinal infection

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1. scibot 24 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.043
  
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sciencedirect.com/science/article/pii/S0092867425003952
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Chalkophore mediated respiratory oxidase flexibility controls M. tuberculosis virulence

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1. scibot 19 Apr 2025
  
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  DOI: 10.7554/eLife.105794.2
  
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elifesciences.org/reviewed-preprints/105794
Mar 2025
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Tumor-derived arachidonic acid reprograms neutrophils to promote immune suppression and therapy resistance in triple-negative breast cancer

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.03.002
  
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sciencedirect.com/science/article/pii/S1074761325000962
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Neutrophil recruitment during intestinal inflammation primes Salmonella elimination by commensal E. coli in a context-dependent manner

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1. scibot 06 Mar 2025
  
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  DOI: 10.1016/j.chom.2025.02.004
  
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sciencedirect.com/science/article/pii/S1931312825000526
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Splenic TNF-α signaling potentiates the innate-to-adaptive transition of antiviral NK cells

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1. scibot 04 Mar 2025
  
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  DOI: 10.1016/j.immuni.2025.02.012
  
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sciencedirect.com/science/article/pii/S1074761325000792
Feb 2025
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A bladder-blood immune barrier constituted by suburothelial perivascular macrophages restrains uropathogen dissemination

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1. scibot 27 Feb 2025
  
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  DOI: 10.1016/j.immuni.2025.02.002
  
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sciencedirect.com/science/article/pii/S107476132500069X
Dec 2024
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Interleukin-1α release during necrotic-like cell death generates myeloid-driven immunosuppression that restricts anti-tumor immunity

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.ccell.2024.10.014
  
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sciencedirect.com/science/article/pii/S1535610824004021
Nov 2024
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Meningeal neutrophil immune signaling influences behavioral adaptation following threat

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1. scibot 24 Nov 2024
  
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  DOI: 10.1016/j.neuron.2024.10.018
  
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sciencedirect.com/science/article/pii/S0896627324007669
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Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy

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1. scibot 11 Nov 2024
  
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  DOI: 10.1016/j.ccell.2024.10.008
  
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sciencedirect.com/science/article/pii/S1535610824003969
Sep 2024
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Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.xcrm.2024.101718
  
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sciencedirect.com/science/article/pii/S2666379124004397
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Glioblastoma induces the recruitment and differentiation of dendritic-like “hybrid” neutrophils from skull bone marrow

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.ccell.2024.08.008
  
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sciencedirect.com/science/article/pii/S1535610824003076
Aug 2024
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LIFR regulates cholesterol-driven bidirectional hepatocyte–neutrophil cross-talk to promote liver regeneration

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1. scibot 23 Aug 2024
  
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  DOI: 10.1038/s42255-024-01110-y
  
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nature.com/articles/s42255-024-01110-y
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Airway extracellular LTA4H concentrations are governed by release from liver hepatocytes and changes in lung vascular permeability

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1. scibot 21 Aug 2024
  
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  DOI: 10.1016/j.celrep.2024.114630
  
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sciencedirect.com/science/article/pii/S221112472400980X
Jun 2024
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Fasting reshapes tissue-specific niches to improve NK cell-mediated anti-tumor immunity

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.immuni.2024.05.021
  
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Dermal TRPV1 innervations engage a macrophage- and fibroblast-containing pathway to activate hair growth in mice

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1. scibot 21 Jun 2024
  
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  DOI: 10.1016/j.devcel.2024.05.019
  
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Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss

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1. scibot 05 Jun 2024
  
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  DOI: 10.1016/j.cell.2024.05.003
  
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sciencedirect.com/science/article/pii/S0092867424004926
May 2024
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Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy

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1. scibot 17 May 2024
  
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  DOI: 10.1016/j.ccell.2024.04.011
  
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Chemoradiotherapy-induced ACKR2+ tumor cells drive CD8+ T cell senescence and cervical cancer recurrence

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1. scibot 09 May 2024
  
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  DOI: 10.1016/j.xcrm.2024.101550
  
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Impaired autophagy in myeloid cells aggravates psoriasis-like skin inflammation through the IL-1β/CXCL2/neutrophil axis

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1. scibot 09 May 2024
  
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  DOI: 10.1186/s13578-024-01238-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11069248/
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Chalkophore mediated respiratory oxidase flexibility controls M. tuberculosis virulence

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1. scibot 01 May 2024
  
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  DOI: 10.1101/2024.04.12.589290
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11030325/
Apr 2024
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QDPR deficiency drives immune suppression in pancreatic cancer

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1. scibot 23 Apr 2024
  
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  DOI: 10.1016/j.cmet.2024.03.015
  
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sciencedirect.com/science/article/pii/S1550413124001190
Mar 2024
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Biofilm exopolysaccharides alter sensory-neuron-mediated sickness during lung infection

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1. scibot 22 Mar 2024
  
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  DOI: 10.1016/j.cell.2024.03.001
  
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Tonic TCR and IL-1β signaling mediate phenotypic alterations of naive CD4+ T cells

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1. scibot 19 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113954
  
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2. scibot 19 Mar 2024
  
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  DOI: 10.1016/j.celrep.2024.113954
  
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Neutrophil-inflicted vasculature damage suppresses immune-mediated optic nerve regeneration

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Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers

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Wnt5 controls splenic myelopoiesis and neutrophil functional ambivalency during DSS-induced colitis

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Salmonella T3SS-2 virulence enhances gut-luminal colonization by enabling chemotaxis-dependent exploitation of intestinal inflammation

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Ly6C+ monocytes in the skin promote systemic alphavirus dissemination

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Maternal inflammation regulates fetal emergency myelopoiesis

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Extracellular-vesicle-packaged S100A11 from osteosarcoma cells mediates lung premetastatic niche formation by recruiting gMDSCs

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Neutrophil depletion attenuates acute renal injury after exhaustive exercise in mice

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Renal macrophages monitor and remove particles from urine to prevent tubule obstruction

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Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis

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The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer

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Engineering irradiated tumor-derived microparticles as personalized vaccines to enhance anti-tumor immunity

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The circadian clock time tunes axonal regeneration

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Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals

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Oct 2023
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Intravital microscopy of satellite cell dynamics and their interaction with myeloid cells during skeletal muscle regeneration

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Neutrophils resist ferroptosis and promote breast cancer metastasis through aconitate decarboxylase 1

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Neutrophil extracellular traps enhance S. aureus skin colonization by oxidative stress induction and downregulation of epidermal barrier genes

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Crisaborole Inhibits Itch and Pain by Preventing Neutrophil Infiltration in a Mouse Model of Atopic Dermatitis

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An agonistic anti-signal regulatory protein α antibody for chronic inflammatory diseases

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CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells

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The glycolysis/HIF-1α axis defines the inflammatory role of IL-4-primed macrophages

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LIFR recruits HGF-producing neutrophils to promote liver injury repair and regeneration

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Neutrophil Conversion to a Tumor-Killing Phenotype Underpins Effective Microbial Therapy

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Age-dependent differences in efferocytosis determine the outcome of opsonophagocytic protection from invasive pathogens

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T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants

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LCN2 secreted by tissue-infiltrating neutrophils induces the ferroptosis and wasting of adipose and muscle tissues in lung cancer cachexia

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Feb 2023
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Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer

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Pregnancy-induced changes to the gut microbiota drive macrophage pyroptosis and exacerbate septic inflammation

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Neutrophil-activating therapy for the treatment of cancer

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The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice

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  DOI: 10.1016/j.xcrm.2022.100893
  
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Oct 2022
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Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation

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Aug 2022
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Immuno-genomic profiling of biopsy specimens predicts neoadjuvant chemotherapy response in esophageal squamous cell carcinoma

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Jul 2022
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Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection

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  DOI: 10.1016/j.immuni.2022.06.021
  
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Androgens drive sexual dimorphism in liver metastasis by promoting hepatic accumulation of neutrophils

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  DOI: 10.1016/j.celrep.2022.110987
  
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Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer

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Macrophage network dynamics depend on haptokinesis for optimal local surveillance

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A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx

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Bacterial infection disrupts established germinal center reactions through monocyte recruitment and impaired metabolic adaptation

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Helminth resistance is mediated by differential activation of recruited monocyte-derived alveolar macrophages and arginine depletion

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GM-CSF production by non-classical monocytes controls antagonistic LPS-driven functions in allergic inflammation

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Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis

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Resident macrophage-dependent immune cell scaffolds drive anti-bacterial defense in the peritoneal cavity

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A TLR7 antagonist restricts interferon-dependent and -independent immunopathology in a mouse model of severe influenza

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Live Imaging of SARS-CoV-2 Infection in Mice Reveals that Neutralizing Antibodies Require Fc Function for Optimal Efficacy

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Modulating tumor infiltrating myeloid cells to enhance bispecific antibody-driven T cell infiltration and anti-tumor response

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Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming

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Gain-of-function p53R172H mutation drives accumulation of neutrophils in pancreatic tumors, promoting resistance to immunotherapy

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Exploring the longitudinal glioma microenvironment landscape uncovers reprogrammed pro-tumorigenic neutrophils in the bone marrow

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A Neutrophil Timer Coordinates Immune Defense and Vascular Protection

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Lipopolysaccharide-mediated chronic inflammation promotes tobacco carcinogen-induced lung cancer and determines the efficacy of immunotherapy

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Autophagy suppresses the formation of hepatocyte-derived cancer-initiating ductular progenitor cells in the liver

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  DOI: 10.1126/sciadv.abf9141
  
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GPR34-mediated sensing of lysophosphatidylserine released by apoptotic neutrophils activates type 3 innate lymphoid cells to mediate tissue repair

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Lactate dehydrogenase A-dependent aerobic glycolysis promotes natural killer cell anti-viral and anti-tumor function

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  DOI: 10.1016/j.celrep.2021.109210
  
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Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis

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Interleukin-10 Prevents Pathological Microglia Hyperactivation following Peripheral Endotoxin Challenge

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Co-option of Neutrophil Fates by Tissue Environments

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The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis

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PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression

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Interaction between Staphylococcus Agr virulence and neutrophils regulates pathogen expansion in the skin

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Liver-specific T regulatory type-1 cells program local neutrophils to suppress hepatic autoimmunity via CRAMP

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Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection

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Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness

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  DOI: 10.1016/j.immuni.2017.04.025
  
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IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus

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  DOI: 10.7554/eLife.45501
  
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Transcriptional Diversity and Niche-Specific Distribution of Leukocyte Populations during Staphylococcus aureus Craniotomy-Associated Biofilm Infection

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  DOI: 10.4049/jimmunol.2001042
  
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Oct 2020
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Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury

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Sep 2020
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Astrocyte- and Neuron-Derived CXCL1 Drives Neutrophil Transmigration and Blood-Brain Barrier Permeability in Viral Encephalitis

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Hookworms Evade Host Immunity by Secreting a Deoxyribonuclease to Degrade Neutrophil Extracellular Traps

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Neutrophils Driving Unconventional T Cells Mediate Resistance against Murine Sarcomas and Selected Human Tumors

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  DOI: 10.1016/j.cell.2019.05.047
  
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BPS Publications

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  DOI: 10.1111/bph.14765
  
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Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis

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  DOI: 10.1016/j.ccell.2019.08.003
  
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Neutrophil Extracellular Traps Initiate Gallstone Formation

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  DOI: 10.1016/j.immuni.2019.07.002
  
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The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity

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  DOI: 10.1016/j.celrep.2019.10.111
  
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Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization

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  DOI: 10.1016/j.celrep.2019.09.055
  
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Bystander Activation of Pulmonary Trm Cells Attenuates the Severity of Bacterial Pneumonia by Enhancing Neutrophil Recruitment

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  DOI: 10.1016/j.celrep.2019.11.103
  
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  DOI: 10.1016/j.chom.2019.02.004
  
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Staphylococcus aureus Leukocidins Target Endothelial DARC to Cause Lethality in Mice

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  DOI: 10.1016/j.chom.2019.01.015
  
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A Neutrophil Timer Coordinates Immune Defense and Vascular Protection

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  DOI: 10.7554/eLife.45501
  
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The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment

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Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination

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Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment

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Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis

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Daily Rhythms of TNFα Expression and Food Intake Regulate Synchrony of Plasmodium Stages with the Host Circadian Cycle

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Aerobic Glycolysis Controls Myeloid-Derived Suppressor Cells and Tumor Immunity via a Specific CEBPB Isoform in Triple-Negative Breast Cancer

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Untitled document

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Dietary Fiber Confers Protection against Flu by Shaping Ly6c− Patrolling Monocyte Hematopoiesis and CD8+ T Cell Metabolism

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Dietary Manganese Promotes Staphylococcal Infection of the Heart

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1. scibot 08 Nov 2017
  
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Inflammatory Ly6Chigh Monocytes Protect against Candidiasis through IL-15-Driven NK Cell/Neutrophil Activation

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1. scibot 08 Nov 2017
  
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Interferon-λ Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness

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