Hypothesis

77 Matching Annotations

Sep 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225017985-main-html.html

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1. scibot 16 Sep 2025
  
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  DOI: 10.1016/j.isci.2025.113537
  
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52.53.155.43/bfa103a56e03ca8260532bade686a824030c14b2/1-s2.0-S2589004225017985-main-html.html
Aug 2025
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Mutations in MLL3 promote breast cancer progression via HIF1α-dependent intratumoral recruitment and differentiation of regulatory T cells

1
1. scibot 01 Aug 2025
  
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  DOI: 10.1016/j.immuni.2025.07.008
  
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sciencedirect.com/science/article/pii/S1074761325003176
Jul 2025
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Adoptively transferred Th17 cells cooperate with host B cells to achieve durable tumor immunity

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1. scibot 25 Jul 2025
  
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  DOI: 10.1016/j.ccell.2025.07.001
  
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sciencedirect.com/science/article/pii/S1535610825002727
May 2025
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IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis

1
1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.004
  
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sciencedirect.com/science/article/pii/S1074761325001670
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Age-related impairment of intestinal inflammation resolution through an eicosanoid-immune-microbiota axis

1
1. scibot 17 May 2025
  
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  DOI: 10.1016/j.chom.2025.04.014
  
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sciencedirect.com/science/article/pii/S1931312825001477
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Macrophages direct location-dependent recall of B cell memory to vaccination

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.005
  
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sciencedirect.com/science/article/pii/S0092867425004076
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Understanding and reversing mammary tumor-driven reprogramming of myelopoiesis to reduce metastatic spread

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.ccell.2025.04.007
  
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sciencedirect.com/science/article/pii/S1535610825001667
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

ULBP2 Promotes Tumor Progression by Suppressing NKG2D-Mediated Anti-Tumor Immunity

1
1. scibot 19 Apr 2025
  
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  RRID:AB_1107773
  
  DOI: 10.3390/ijms26072950
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11988498/
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Optimizing stem cell infusion timing in the prevention of acute graft-versus-host disease

1
1. scibot 01 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.022
  
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sciencedirect.com/science/article/pii/S0092867425002958
Mar 2025
52.53.155.43 52.53.155.43

PDF-html.html

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1. scibot 24 Mar 2025
  
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  RRID:AB_1107773
  
  DOI: 10.1158/1535-7163.mct-24-0715
  
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52.53.155.43/e942259e59872c6a1fa180712f861e9e05fe5109/PDF-html.html
www.cell.com www.cell.com

Temporal dynamics of immune cell transcriptomics in brain metastasis progression influenced by gut microbiome dysbiosis

1
1. scibot 05 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115356
  
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cell.com/cell-reports/abstract/S2211-1247(25)00127-5
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Splenic TNF-α signaling potentiates the innate-to-adaptive transition of antiviral NK cells

1
1. scibot 04 Mar 2025
  
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  RRID:AB_1107773
  
  DOI: 10.1016/j.immuni.2025.02.012
  
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sciencedirect.com/science/article/pii/S1074761325000792
Feb 2025
aacrjournals.org aacrjournals.org

Crosstalk between myeloid and B cells shapes the distinct microenvironments of primary and secondary liver cancer

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1. scibot 13 Feb 2025
  
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  RRID:AB_1107773
  
  DOI: 10.1158/0008-5472.CAN-23-0193
  
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aacrjournals.org/cancerres/article/83/21/3544/729719/Cross-talk-between-Myeloid-and-B-Cells-Shapes-the
Dec 2024
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 13 Dec 2024
  
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  RRID:AB_1107773
  
  DOI: 10.1111/bph.17404
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17404
52.53.155.43 52.53.155.43

Heightened Innate Immune State Induced by Viral Vector Leads to Enhanced Response to Challenge and Prolongs Malaria Vaccine Protection

1
1. scibot 06 Dec 2024
  
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  DOI: 10.1016/j.isci.2024.111468
  
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52.53.155.43/f4fd647defec02b27a99572a8bdfe7f7e8766183/1-s2.0-S2589004224026956-main-html.html
Nov 2024
www.sciencedirect.com www.sciencedirect.com

Pericancerous cross-presentation to cytotoxic T lymphocytes impairs immunotherapeutic efficacy in hepatocellular carcinoma

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1. scibot 21 Nov 2024
  
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  RRID:AB_1107773
  
  DOI: 10.1016/j.ccell.2024.10.012
  
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sciencedirect.com/science/article/pii/S1535610824004008
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Probiotics and their metabolite spermidine enhance IFN-γ+CD4+ T cell immunity to inhibit hepatitis B virus

1
1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.xcrm.2024.101822
  
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sciencedirect.com/science/article/pii/S2666379124005937
Aug 2024
www.biorxiv.org www.biorxiv.org

T cells regulate intestinal motility and shape enteric neuronal responses to intestinal microbiota.

1
1. scibot 14 Aug 2024
  
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  BE0091
  
  DOI: 10.1101/2024.05.23.595563
  
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biorxiv.org/content/10.1101/2024.05.23.595563v2
Jul 2024
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Immune Checkpoint Inhibition-related Neuroinflammation Disrupts Cognitive Function

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1. scibot 16 Jul 2024
  
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  DOI: 10.1101/2024.07.01.601087
  
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biorxiv.org/content/10.1101/2024.07.01.601087v1
Apr 2024
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Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages

1
1. scibot 18 Apr 2024
  
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  DOI: 10.1016/j.immuni.2024.03.020
  
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sciencedirect.com/science/article/pii/S1074761324001419
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Type I interferons induce an epigenetically distinct memory B cell subset in chronic viral infection

1
1. scibot 09 Apr 2024
  
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  DOI: 10.1016/j.immuni.2024.03.016
  
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sciencedirect.com/science/article/pii/S1074761324001377
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An autophagy program that promotes T cell egress from the lymph node controls responses to immune checkpoint blockade

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1. scibot 02 Apr 2024
  
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  BioXcell#BE0091
  
  DOI: 10.1016/j.celrep.2024.114020
  
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sciencedirect.com/science/article/pii/S2211124724003486
Feb 2024
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An axon-T cell feedback loop enhances inflammation and axon degeneration

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1. scibot 06 Feb 2024
  
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  BioXCellCat: BE0091
  
  DOI: 10.1016/j.celrep.2024.113721
  
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sciencedirect.com/science/article/pii/S2211124724000494
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

DNA damage repair profiling of esophageal squamous cell carcinoma uncovers clinically relevant molecular subtypes with distinct prognoses and therapeutic vulnerabilities

1
1. scibot 19 Jan 2024
  
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  AB_1107773
  
  DOI: 10.1016/j.ebiom.2023.104801
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10518355/
Oct 2023
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Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation

1
1. scibot 28 Oct 2023
  
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  DOI: 10.1016/j.celrep.2023.113323
  
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sciencedirect.com/science/article/pii/S2211124723013359
Aug 2023
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KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells

1
1. scibot 25 Aug 2023
  
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  RRID:AB_1107773
  
  DOI: 10.1016/j.ccell.2023.07.002
  
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sciencedirect.com/science/article/abs/pii/S1535610823002428
52.53.155.43 52.53.155.43

PIIS2211124723009622-html.html

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1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112951
  
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52.53.155.43/ab78471f0bcea9a54e77e384546909131002deb2/PIIS2211124723009622-html.html
52.53.155.43 52.53.155.43

CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells

2
1. scibot 17 Aug 2023
  
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  RRID:AB_1107773
  
  DOI: 10.1016/j.xcrm.2023.101151
  
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2. scibot 11 Aug 2023
  
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  RRID:AB_1107773
  
  DOI: 10.1016/j.xcrm.2023.101151
  
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52.53.155.43/75914c2645b295883453ae6f0848b8ff04ccb7e0/PIIS266637912300304X-html.html
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Synergism Between IL21 and Anti-PD-1 Combination Therapy is Underpinned by the Coordinated Reprogramming of the Immune Cellular Network in the Tumor Microenvironment

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1. scibot 10 Aug 2023
  
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  DOI: 10.1158/2767-9764.CRC-23-0012
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10402650/
52.53.155.43 52.53.155.43

can-23-0193-html.html

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1. scibot 04 Aug 2023
  
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  RRID:AB_1107773
  
  DOI: 10.1158/0008-5472.CAN-23-0193
  
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52.53.155.43/724675bb87e06403c590d0acecc9940852845416/can-23-0193-html.html
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses

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1. scibot 08 Jul 2023
  
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  RRID:AB_1107773
  
  DOI: 10.1158/2643-3230.BCD-22-0029
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9816815/
Jun 2023
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Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses

1
1. scibot 23 Jun 2023
  
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  RRID:AB_1107773
  
  DOI: 10.1016/j.immuni.2023.05.011
  
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sciencedirect.com/science/article/pii/S1074761323002285
May 2023
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STAT3 signaling in B cells controls germinal center zone organization and recycling

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1. scibot 18 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112512
  
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sciencedirect.com/science/article/pii/S2211124723005235
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Immune mechanisms shape the clonal landscape during early progression of prostate cancer

1
1. scibot 06 May 2023
  
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  RRID:AB_1107773
  
  DOI: 10.1016/j.devcel.2023.04.010
  
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sciencedirect.com/science/article/pii/S1534580723001806
Apr 2023
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The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries

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Galectin-3 expression in donor T cells reduces GvHD severity and lethality after allogeneic hematopoietic cell transplantation

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Thymus Antibody-Secreting Cells Possess an Interferon Gene Signature and are Preferentially Expanded in Young Female Mice

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IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment

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Neutrophil-activating therapy for the treatment of cancer

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GATA4 controls regionalization of tissue immunity and commensal-driven immunopathology

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Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma

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Microglia drive transient insult-induced brain injury by chemotactic recruitment of CD8+ T lymphocytes

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Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells

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STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation

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Obesity enhances antiviral immunity in the genital mucosa through a microbiota-mediated effect on γδ T cells

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Neuropilin-1 cooperates with PD-1 in CD8+ T-cells predicting outcomes in melanoma patients treated with anti-PD1

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The C5a-C5aR1 complement axis is essential for neutrophil recruitment to draining lymph nodes via high endothelial venules in cutaneous leishmaniasis

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Mycobacterium tuberculosis impedes CD40-dependent notch signaling to restrict Th17 polarization during infection

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Germinal center expansion but not plasmablast differentiation is proportional to peptide-MHCII density via CD40-CD40L signaling strength

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Negative Immune Checkpoint Protein, VISTA, Regulates the CD4+ Treg Population During Sepsis Progression to Promote Acute Sepsis Recovery and Survival

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Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa

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Inflammatory macrophages exploit unconventional pro-phagocytic integrins for phagocytosis and anti-tumor immunity

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Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance

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Expeditious recruitment of circulating memory CD8 T cells to the liver facilitates control of malaria

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CXCL10/CXCR3 signaling contributes to an inflammatory microenvironment and its blockade enhances progression of murine pancreatic precancerous lesions

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Untitled document

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Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells

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  InVivoMAb polyclonal Armenian hamster IgG clone N/A
  
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Interferon-γ Drives Treg Fragility to Promote Anti-tumor Immunity

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Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop

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Dynamic modulation of spleen germinal center reactions by gut bacteria during Plasmodium infection

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Reciprocal communication between astrocytes and endothelial cells is required for astrocytic glutamate transporter 1 (GLT-1) expression

1
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TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate

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Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection

1
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Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation

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Gut Microbiota Composition Modulates the Magnitude and Quality of Germinal Centers during Plasmodium Infections

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Mutant EZH2 Induces a Pre-malignant Lymphoma Niche by Reprogramming the Immune Response

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Inflammation-Induced Lactate Leads to Rapid Loss of Hepatic Tissue-Resident NK Cells

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FOXD3 Regulates VISTA Expression in Melanoma

1
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Jan 2020
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Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8+ T Cells

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1. scibot 13 Jan 2020
  
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  RRID:AB_1107773
  
  DOI: 10.1016/j.cmet.2019.05.016
  
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  Curator: @ethanbadger
  
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cell.com/cell-metabolism/fulltext/S1550-4131(19)30256-6
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Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors

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1. scibot 13 Jan 2020
  
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  RRID:AB_1107773
  
  DOI: 10.1016/j.ccell.2019.05.004
  
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sciencedirect.com/science/article/pii/S1535610819302429
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Liver-Derived Signals Sequentially Reprogram Myeloid Enhancers to Initiate and Maintain Kupffer Cell Identity

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1. scibot 13 Jan 2020
  
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  RRID:AB_1107773
  
  DOI: 10.1016/j.immuni.2019.09.002
  
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  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1074761319303735
Nov 2018
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CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity

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1. scibot 05 Nov 2018
  
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  Curator: @Jmenke
  
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  RRID:AB_1107773 RRIDCUR:Validated
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www-sciencedirect-com.ezproxy.is.ed.ac.uk/science/article/pii/S107476131830342X
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Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S1097276518305999
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Staphylococcus aureus Virulent PSMα Peptides Induce Keratinocyte Alarmin Release to Orchestrate IL-17-Dependent Skin Inflammation

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1. scibot 05 Nov 2018
  
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  RRID:AB_1107773
  
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sciencedirect.com/science/article/pii/S1931312817304432
Nov 2017
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Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase

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1. scibot 08 Nov 2017
  
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  BioXCellCat#BE0091
  
  Curator: @bandrow
  
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  (Bio X Cell Cat# BE0091, RRID:AB_1107773)
  
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sciencedirect.com/science/article/pii/S1074761317302339

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