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  1. Last 7 days
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    Macrophages preserve endothelial cell specialization in the adrenal gland to modulate aldosterone secretion and blood pressure
    1
    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114395

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    cell.com/cell-reports/abstract/S2211-1247(24)00723-X
  3. Jun 2024
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    A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML
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      DOI: 10.1016/j.xcrm.2024.101592

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  5. May 2024
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    Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng
    2
    1. scibot 31 May 2024
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    2. scibot 31 May 2024
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    Expression of the membrane tetraspanin claudin 18 on cancer cells promotes T lymphocyte infiltration and antitumor immunity in pancreatic cancer
    1
    1. scibot 16 May 2024
      BioXCellCat#BP0088

      DOI: 10.1016/j.immuni.2024.04.021

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    sciencedirect.com/science/article/pii/S1074761324002267
  8. Apr 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression
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    1. scibot 03 Apr 2024
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      DOI: 10.1158/2159-8290.CD-23-0240

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    ncbi.nlm.nih.gov/pmc/articles/PMC10922937/
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    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
    1
    1. scibot 02 Apr 2024
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  11. Mar 2024
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    Hippo-signaling-controlled MHC class I antigen processing and presentation pathway potentiates antitumor immunity
    1
    1. scibot 27 Mar 2024
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    Long-lasting mRNA-encoded interleukin-2 restores CD8+ T cell neoantigen immunity in MHC class I-deficient cancers
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    sciencedirect.com/science/article/pii/S1535610824000576
  14. Jan 2024
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    Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms
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    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.ccell.2023.12.018

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    sciencedirect.com/science/article/pii/S1535610823004464
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    Skin microbe-dependent TSLP-ILC2 priming axis in early life is co-opted in allergic inflammation
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    1. scibot 11 Jan 2024
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    sciencedirect.com/science/article/pii/S1931312823005012
  17. Nov 2023
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    A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression
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    1. scibot 17 Nov 2023
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    sciencedirect.com/science/article/pii/S1534580723005518
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    Targeting intracellular oncoproteins with dimeric IgA promotes expulsion from the cytoplasm and immune-mediated control of epithelial cancers
    1
    1. scibot 02 Nov 2023
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      DOI: 10.1016/j.immuni.2023.09.013

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    sciencedirect.com/science/article/pii/S1074761323004181
  20. Oct 2023
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    Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113323

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    sciencedirect.com/science/article/pii/S2211124723013359
  22. Sep 2023
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    Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control
    1
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    sciencedirect.com/science/article/pii/S2211124723010586
  24. Jul 2023
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    Lung injury induces a polarized immune response by self-antigen-specific CD4+ Foxp3+ regulatory T cells
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    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112839

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    TCR-independent CD137 (4-1BB) signaling promotes CD8+-exhausted T cell proliferation and terminal differentiation
    1
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      DOI: 10.1016/j.immuni.2023.06.007

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    sciencedirect.com/science/article/pii/S1074761323002649
  27. Jun 2023
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    Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses
    1
    1. scibot 23 Jun 2023
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    sciencedirect.com/science/article/pii/S1074761323002285
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    DNA hypomethylation silences anti-tumor immune genes in early prostate cancer and CTCs
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    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.cell.2023.05.028

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    sciencedirect.com/science/article/pii/S0092867423005809
  30. May 2023
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    Immune mechanisms shape the clonal landscape during early progression of prostate cancer
    1
    1. scibot 06 May 2023
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    sciencedirect.com/science/article/pii/S1534580723001806
  32. Apr 2023
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    Semi-Supervised Analysis of myeloid and T cell behaviour in ex vivo ovarian tumour slices reveals changes in cell motility after treatments
    1
    1. scibot 23 Apr 2023
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    sciencedirect.com/science/article/pii/S2589004223005916
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    Dysregulated lung stroma drives emphysema exacerbation by potentiating resident lymphocytes to suppress an epithelial stem cell reservoir
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    1. scibot 20 Apr 2023
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    sciencedirect.com/science/article/pii/S1074761323000444
  35. Mar 2023
  36. www.biorxiv.org www.biorxiv.org
    “Tumor Explants Elucidate a Cascade of Paracrine SHH, WNT, and VEGF Signals Driving Pancreatic Cancer Angiosuppression”
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      DOI: 10.1101/2023.03.02.529724

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    biorxiv.org/content/10.1101/2023.03.02.529724v1
  37. Feb 2023
  38. www.sciencedirect.com www.sciencedirect.com
    PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor T cell immunotherapy
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    sciencedirect.com/science/article/pii/S1550413123000104
  39. Jan 2023
  40. 52.53.155.43 52.53.155.43
    SSRN-id4272137-html.html
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      DOI: 10.2139/ssrn.4272137

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    T cell-derived interleukin-22 drives the expression of CD155 by cancer cells to suppress NK cell function and promote metastasis
    1
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    GATA4 controls regionalization of tissue immunity and commensal-driven immunopathology
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    1. scibot 12 Jan 2023
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      DOI: 10.1016/j.immuni.2022.12.009

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    sciencedirect.com/science/article/pii/S1074761322006458
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    Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma
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    1. scibot 10 Jan 2023
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    sciencedirect.com/science/article/pii/S1074761322006045
  44. Dec 2022
  45. www.sciencedirect.com www.sciencedirect.com
    IL-5-producing CD4+ T cells and eosinophils cooperate to enhance response to immune checkpoint blockade in breast cancer
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    1. scibot 17 Dec 2022
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    Cancer cell-derived type I interferons instruct tumor monocyte polarization
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  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity
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      DOI: 10.1136/jitc-2022-004806

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    ncbi.nlm.nih.gov/pmc/articles/PMC9703354/
  48. Sep 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
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      DOI: 10.1158/2159-8290.CD-21-1077

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    ncbi.nlm.nih.gov/pmc/articles/PMC8904298/
  50. Aug 2022
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
    1
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      DOI: 10.1016/j.cell.2016.07.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC5002269/
  52. Jun 2022
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9841318/
  54. May 2022
  55. www.sciencedirect.com www.sciencedirect.com
    Newly recruited intraepithelial Ly6A+CCR9+CD4+ T cells protect against enteric viral infection
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      DOI: 10.1016/j.immuni.2022.05.001

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    sciencedirect.com/science/article/pii/S1074761322002217
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    Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity
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      DOI: 10.1016/j.ccell.2022.04.004

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    sciencedirect.com/science/article/pii/S1535610822001660
  57. Apr 2022
  58. www.sciencedirect.com www.sciencedirect.com
    Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma
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    sciencedirect.com/science/article/pii/S2211124722004533
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    TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells
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      DOI: 10.1016/j.celrep.2022.110657

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  60. Feb 2022
  61. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    JAK1 signaling in dendritic cells promotes peripheral tolerance in autoimmunity through PD-L1-mediated regulatory T cell induction
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    Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy
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  63. Dec 2021
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    Tnfrsf4-expressing regulatory T cells promote immune escape of chronic myeloid leukemia stem cells
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    Interleukin-10 receptor signaling promotes the maintenance of a PD-1int TCF-1+ CD8+ T cell population that sustains anti-tumor immunity
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  66. Nov 2021
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    Expeditious recruitment of circulating memory CD8 T cells to the liver facilitates control of malaria
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  68. Oct 2021
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    Synergistic effect of non-neutralizing antibodies and interferon-γ for cross-protection against influenza
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  70. Sep 2021
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  72. Aug 2021
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    Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors
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    The Microbial Metabolite Butyrate Stimulates Bone Formation via T Regulatory Cell-Mediated Regulation of WNT10B Expression
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    The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
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  81. Jul 2021
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    The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
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    A safe and effective mucosal RSV vaccine in mice consisting of RSV phosphoprotein and flagellin variant
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  88. May 2021
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    Discrete limbal epithelial stem cell populations mediate corneal homeostasis and wound healing
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      InVivoMAb Rat IgG1 Isotype control; anti Horseradish Peroxidase

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    The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake
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    Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy
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    CD276 expression enables squamous cell carcinoma stem cells to evade immune surveillance
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  93. Apr 2021
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    Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis
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  96. Feb 2021
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    Cardiolipin-mediated PPARγ S112 phosphorylation impairs IL-10 production and inflammation resolution during bacterial pneumonia
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  98. Nov 2020
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    MicroRNAs of the miR-17~9 family maintain adipose tissue macrophage homeostasis by sustaining IL-10 expression
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  100. Oct 2020
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  102. Sep 2020
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    Th1-Th2 Cross-Regulation Controls Early Leishmania Infection in the Skin by Modulating the Size of the Permissive Monocytic Host Cell Reservoir
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    Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory Cues
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  107. Jan 2020
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    Mucosal infection rewires TNFɑ signaling dynamics to skew susceptibility to recurrence
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    Intraperitoneal cancer-immune microenvironment promotes peritoneal dissemination of gastric cancer
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    Lymphocyte Activation Gene-3 Maintains Mitochondrial and Metabolic Quiescence in Naive CD4+ T Cells
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  114. Nov 2018
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    Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution
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    Quiescent Tissue Stem Cells Evade Immune Surveillance
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    mTORC1 Inactivation Promotes Colitis-Induced Colorectal Cancer but Protects from APC Loss-Dependent Tumorigenesis
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    TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer
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    Interferon-γ-Driven iNOS: A Molecular Pathway to Terminal Shock in Arenavirus Hemorrhagic Fever
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      Curator: @Jmenke

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