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Zeaxanthin augments CD8+ effector T cell function and immunotherapy efficacy

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.xcrm.2025.102324
  
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Cancer cell and microenvironmental rewiring by ADAR1 loss impairs glioblastoma tumor growth and extends survival

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1. scibot 03 Sep 2025
  
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  DOI: 10.1016/j.celrep.2025.116151
  
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sciencedirect.com/science/article/pii/S2211124725009222
Aug 2025
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Long-range deployment of tumor-antigen-specific cytotoxic T lymphocytes inhibits lung metastasis of breast cancer

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1. scibot 28 Aug 2025
  
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  DOI: 10.1016/j.devcel.2025.08.003
  
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An age-related decrease in leptin contributes to CD8+ T cell aging in the tumor microenvironment

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.xcrm.2025.102310
  
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sciencedirect.com/science/article/pii/S2666379125003830
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Lymphoma accelerates T cell and tissue aging

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1. scibot 26 Aug 2025
  
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  DOI: 10.1016/j.ccell.2025.07.023
  
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sciencedirect.com/science/article/pii/S1535610825003290
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TRIM6 ablation reverses ICB resistance in MSS gastric cancer by unleashing cGAS-STING-dependent antitumor immunity

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1. scibot 19 Aug 2025
  
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  DOI: 10.1186/s13046-025-03513-5
  
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Inhibition of tumor cell macropinocytosis driver DHODH reverses immunosuppression and overcomes anti-PD1 resistance

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1. scibot 15 Aug 2025
  
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  DOI: 10.1016/j.immuni.2025.07.013
  
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DNASE1L3-expressing dendritic cells promote CD8+ T cell function and anti-PD-(L)1 therapy efficacy by degrading neutrophil extracellular traps

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1. scibot 15 Aug 2025
  
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  DOI: 10.1016/j.ccell.2025.07.014
  
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cell.com/cancer-cell/abstract/S1535-6108(25)00320-4
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Selective Alanine Transporter Utilization is a Therapeutic Vulnerability in ARID1A-Mutant Ovarian Cancer

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1. scibot 05 Aug 2025
  
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  DOI: 10.1158/0008-5472.CAN-25-0654
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12314749/
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Mutations in MLL3 promote breast cancer progression via HIF1α-dependent intratumoral recruitment and differentiation of regulatory T cells

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1. scibot 01 Aug 2025
  
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  DOI: 10.1016/j.immuni.2025.07.008
  
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sciencedirect.com/science/article/pii/S1074761325003176
Jul 2025
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Adoptively transferred Th17 cells cooperate with host B cells to achieve durable tumor immunity

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1. scibot 25 Jul 2025
  
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  DOI: 10.1016/j.ccell.2025.07.001
  
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Exercise-induced microbiota metabolite enhances CD8 T cell antitumor immunity promoting immunotherapy efficacy

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1. scibot 15 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.06.018
  
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cell.com/cell/fulltext/S0092-8674(25)00684-1
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The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells

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1. scibot 08 Jul 2025
  
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  RRID:AB_1107780
  
  DOI: 10.1016/j.immuni.2025.06.001
  
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sciencedirect.com/science/article/pii/S1074761325002481
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APOE protects against severe infection with Mycobacterium tuberculosis by restraining production of neutrophil extracellular traps

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1. scibot 02 Jul 2025
  
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  DOI: 10.1371/journal.ppat.1013267
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12201663/
Jun 2025
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Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells

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1. scibot 26 Jun 2025
  
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  RRID:AB_1107780
  
  DOI: 10.1016/j.immuni.2025.05.025
  
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sciencedirect.com/science/article/pii/S1074761325002468
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MET pathway inhibition increases chemo-immunotherapy efficacy in small cell lung cancer

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1. scibot 21 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102194
  
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Id2 levels determine the development of effector vs. exhausted tissue-resident memory CD8+ T cells during CNS chronic infection

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1. scibot 18 Jun 2025
  
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  RRID:AB_1107780
  
  DOI: 10.1016/j.celrep.2025.115861
  
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1-s2.0-S2589004225010351-main (1)-html.html

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1. scibot 13 Jun 2025
  
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  RRID:AB_1107780
  
  DOI: 10.1016/j.isci.2025.112774
  
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52.53.155.43/4b335a8bbb2cbd12d3073f7f7af0232585278bec/1-s2.0-S2589004225010351-main (1)-html.html
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Fc-optimized anti-CTLA-4 antibodies increase tumor-associated high endothelial venules and sensitize refractory tumors to PD-1 blockade

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1. scibot 04 Jun 2025
  
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  DOI: 10.1016/j.xcrm.2025.102141
  
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Efflux of N1-acetylspermidine from hepatoma fosters macrophage-mediated immune suppression to dampen immunotherapeutic efficacy

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1. scibot 03 Jun 2025
  
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  DOI: 10.1016/j.immuni.2025.05.006
  
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sciencedirect.com/science/article/pii/S1074761325002274
May 2025
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PD-1 Blockade Mitigates Surgery-Induced Immunosuppression and Increases the Efficacy of Photodynamic Therapy for Pleural Mesothelioma

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1. scibot 28 May 2025
  
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  DOI: 10.1158/2767-9764.CRC-24-0571
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12099492/
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Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis

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1. scibot 22 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.032
  
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Reducing Dietary Protein Enhances the Antitumor Effects of Chemotherapy through Immune-Mediated Mechanisms

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1. scibot 20 May 2025
  
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  DOI: 10.1158/1535-7163.MCT-24-0545
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7617599/
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Metabolic reprogramming through histone lactylation in microglia and macrophages recruits CD8+ T lymphocytes and aggravates spinal cord injury

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1. scibot 18 May 2025
  
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  DOI: 10.1016/j.neuron.2025.04.003
  
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sciencedirect.com/science/article/pii/S0896627325002594
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Sickle cell disease induces chromatin introversion and ferroptosis in CD8+ T cells to suppress anti-tumor immunity

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.020
  
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IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.immuni.2025.04.004
  
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Semaphorin7A and PD-L1 cooperatively drive immunosuppression during mammary involution and breast cancer

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.celrep.2025.115676
  
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Macrophages direct location-dependent recall of B cell memory to vaccination

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.cell.2025.04.005
  
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Bone metastases diminish extraosseous response to checkpoint blockade immunotherapy through osteopontin-producing osteoclasts

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1. scibot 16 May 2025
  
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  DOI: 10.1016/j.ccell.2025.03.036
  
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Apr 2025
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Evolution of tumor stress response during cytoreductive surgery for ovarian cancer

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1. scibot 15 Apr 2025
  
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  DOI: 10.1016/j.isci.2025.112317
  
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Downregulation of PD-L1 expression by Wnt pathway inhibition to enhance PD-1 blockade efficacy in hepatocellular carcinoma

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1. scibot 11 Apr 2025
  
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  DOI: 10.1186/s13062-025-00645-8
  
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link.springer.com/article/10.1186/s13062-025-00645-8
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Inflammatory and anti-inflammatory cytokines bidirectionally modulate amygdala circuits regulating anxiety

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1. scibot 08 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.005
  
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Fluorescence Lifetime Imaging Enables In Vivo Quantification of PD-L1 Expression and Intertumoral Heterogeneity

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1. scibot 05 Apr 2025
  
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  DOI: 10.1158/0008-5472.CAN-24-0880
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11967911/
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Spatial transcriptomics reveals tryptophan metabolism restricting maturation of intratumoral tertiary lymphoid structures

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1. scibot 05 Apr 2025
  
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  DOI: 10.1016/j.ccell.2025.03.011
  
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sciencedirect.com/science/article/pii/S1535610825001126
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PDF-html.html

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1. scibot 04 Apr 2025
  
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  DOI: 10.1158/2326-6066.cir-24-0834
  
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52.53.155.43/b8eb1cd1446295bdd52d11650093cdf439d34361/PDF-html.html
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Cancer-cell-derived cGAMP limits the activity of tumor-associated CD8+ T cells

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1. scibot 03 Apr 2025
  
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Translation dysregulation in cancer as a source for targetable antigens

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PAI-1-driven SFRP2high cancer-associated fibroblasts hijack the abscopal effect of radioimmunotherapy

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Interferon-γ-stimulated antigen-presenting cancer-associated fibroblasts hinder neoadjuvant chemoimmunotherapy efficacy in lung cancer

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Low-dose irradiation of the gut improves the efficacy of PD-L1 blockade in metastatic cancer patients

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Lymph node macrophages drive immune tolerance and resistance to cancer therapy by induction of the immune-regulatory cytokine IL-33

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Inflammatory cytokines mediate the induction of and awakening from metastatic dormancy

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Methionine intervention induces PD-L1 expression to enhance the immune checkpoint therapy response in MTAP-deleted osteosarcoma

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Lung CD4+ resident memory T cells use airway secretory cells to stimulate and regulate onset of allergic airway neutrophilic disease

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Cryoablation does not significantly contribute to systemic effector immune responses in poorly immunogenic B16F10 melanoma model

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Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2

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Acetyl-CoA synthesis in the skin is a key determinant of systemic lipid homeostasis

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Distinct cellular mechanisms underlie chemotherapies and PD-L1 blockade combinations in triple-negative breast cancer

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Divergent sex-specific pannexin-1 mechanisms in microglia and T cells underlie neuropathic pain

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Targeting the mevalonate pathway potentiates NUAK1 inhibition-induced immunogenic cell death and antitumor immunity

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Clonally expanded, targetable, natural killer-like NKG7 T cells seed the aged spinal cord to disrupt myeloid-dependent wound healing

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Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1

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IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages

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A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor

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Flt3L enhances clonal diversification and selective expansion of intratumoral CD8+ T cells while differentiating into effector-like cells

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Pericancerous cross-presentation to cytotoxic T lymphocytes impairs immunotherapeutic efficacy in hepatocellular carcinoma

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can-24-0880-html.html

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Itaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance

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Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy

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Humoral and T-cell-mediated responses to an insect-specific flavivirus-based Zika virus vaccine candidate

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Quiescence and aging of melanocyte stem cells and a novel association with PD-L1

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Beta cell extracellular vesicle PD-L1 as a novel regulator of CD8+ T cell activity and biomarker during the evolution of Type 1 Diabetes

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A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies

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Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell

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Junctional Adhesion Molecule 2 Represents a Subset of Hematopoietic Stem Cells with Enhanced Potential for T Lymphopoiesis

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Glioblastoma induces the recruitment and differentiation of dendritic-like “hybrid” neutrophils from skull bone marrow

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Type I interferon signaling regulates myeloid and T cell crosstalk in the glioblastoma tumor microenvironment

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PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8+ T cell ferroptosis

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Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression

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Uncovering therapeutic targets for macrophage-mediated T cell suppression and PD-L1 therapy sensitization

1
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  DOI: 10.1016/j.xcrm.2024.101698
  
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The cytokine Meteorin-like inhibits anti-tumor CD8+ T cell responses by disrupting mitochondrial function

2
1. scibot 19 Aug 2024
  
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  DOI: 10.1016/j.immuni.2024.07.003
  
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  DOI: 10.1016/j.immuni.2024.07.003
  
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Type I conventional dendritic cells facilitate immunotherapy in pancreatic cancer

1
1. scibot 25 Jul 2024
  
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  DOI: 10.1126/science.adh4567
  
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Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function

1
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  DOI: 10.1016/j.celrep.2024.114506
  
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Proteobacteria impair anti-tumor immunity in the omentum by consuming arginine

1
1. scibot 18 Jul 2024
  
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  AB_1107780
  
  DOI: 10.1016/j.chom.2024.06.003
  
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Progestogen-driven B7-H4 contributes to onco-fetal immune tolerance

1
1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.cell.2024.06.012
  
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Cyclin dependent kinase 9 inhibition reduced programmed death-ligand 1 expression and improved treatment efficacy in hepatocellular carcinoma

1
1. scibot 12 Jul 2024
  
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  DOI: 10.1016/j.heliyon.2024.e34289
  
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Stabilizing Tumor-Resident Mast Cells Restores T-Cell Infiltration and Sensitizes Sarcomas to PD-L1 Inhibition

2
1. scibot 07 Jun 2024
  
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  RRID:AB_1107780
  
  DOI: 10.1158/1078-0432.CCR-24-0246
  
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  DOI: 10.1158/1078-0432.CCR-24-0246
  
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A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML

1
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  DOI: 10.1016/j.xcrm.2024.101592
  
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Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss

1
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  DOI: 10.1016/j.cell.2024.05.003
  
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Blockage of L2HGDH-mediated S-2HG catabolism orchestrates macrophage polarization to elicit antitumor immunity

1
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  DOI: 10.1016/j.celrep.2024.114300
  
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Tumor cells impair immunological synapse formation via central nervous system-enriched metabolite

2
1. scibot 31 May 2024
  
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Deletion of the mRNA endonuclease Regnase-1 promotes NK cell anti-tumor activity via OCT2-dependent transcription of Ifng

2
1. scibot 31 May 2024
  
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Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy

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  AB_1107780
  
  DOI: 10.1016/j.cell.2024.04.015
  
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Apr 2024
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Batf3+ DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacy

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  DOI: 10.1016/j.celrep.2024.114141
  
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QDPR deficiency drives immune suppression in pancreatic cancer

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Tim4 enables large peritoneal macrophages to cross-present tumor antigens at early stages of tumorigenesis

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  RRID:AB_1107780
  
  DOI: 10.1016/j.celrep.2024.114096
  
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CXCL9/10-engineered dendritic cells promote T cell activation and enhance immune checkpoint blockade for lung cancer

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  DOI: 10.1016/j.xcrm.2024.101479
  
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Targeting branched N-glycans and fucosylation sensitizes ovarian tumors to immune checkpoint blockade

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  DOI: 10.1038/s41467-024-47069-y
  
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Mar 2024
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Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells

3
1. scibot 01 Mar 2024
  
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  DOI: 10.1016/j.ccell.2024.02.004
  
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  DOI: 10.1016/j.ccell.2024.02.004
  
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UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity

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1. scibot 28 Feb 2024
  
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  DOI: 10.1016/j.molcel.2024.01.024
  
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Scarring hair follicle destruction is driven by the collapse of EGFR-protected JAK-STAT1-sensitive stem cell immune privilege

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1. scibot 23 Feb 2024
  
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  DOI: 10.1101/2023.10.11.561653
  
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Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks

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Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells

1
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  DOI: 10.1016/j.cmet.2024.01.005
  
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Amphiregulin from regulatory T cells promotes liver fibrosis and insulin resistance in non-alcoholic steatohepatitis

2
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  RRID:AB_1107780
  
  DOI: 10.1016/j.immuni.2024.01.009
  
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Interrogation of endothelial and mural cells in brain metastasis reveals key immune-regulatory mechanisms

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  DOI: 10.1016/j.ccell.2023.12.018
  
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DNA damage repair profiling of esophageal squamous cell carcinoma uncovers clinically relevant molecular subtypes with distinct prognoses and therapeutic vulnerabilities

1
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Skin microbe-dependent TSLP-ILC2 priming axis in early life is co-opted in allergic inflammation

1
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  DOI: 10.1016/j.chom.2023.12.006
  
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Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells

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  DOI: 10.1016/j.devcel.2023.07.025
  
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More time to kill: a longer liver stage increases T cell-mediated protection against pre-erythrocytic malaria

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  DOI: 10.1016/j.isci.2023.108489
  
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Helicobacter pylori CagA promotes immune evasion of gastric cancer by upregulating PD-L1 level in exosomes

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Early cellular mechanisms of type I interferon-driven susceptibility to tuberculosis

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The tumor-derived cytokine Chi3l1 induces neutrophil extracellular traps that promote T cell exclusion in triple-negative breast cancer

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Trans-vaccenic acid reprograms CD8+ T cells and anti-tumour immunity

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A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression

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PD-L1-mediated immune evasion in triple-negative breast cancer is linked to the loss of ZNF652

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Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation

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Dietary fructose-mediated adipocyte metabolism drives antitumor CD8+ T cell responses

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Intermittent fasting induced ketogenesis inhibits mouse epithelial ovarian cancer by promoting antitumor T cell response

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Oncolytic virus M1 functions as a bifunctional checkpoint inhibitor to enhance the antitumor activity of DC vaccine

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Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease

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Supplementation with a high-glucose drink stimulates anti-tumor immune responses to glioblastoma via gut microbiota modulation

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Upregulation of exosome secretion from tumor-associated macrophages plays a key role in the suppression of anti-tumor immunity

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Glioblastoma vascular plasticity limits effector T-cell infiltration and is blocked by cAMP activation

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Endothelial cells are a key target of IFN-g during response to combined PD-1/CTLA-4 ICB treatment in a mouse model of bladder cancer

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Molecular, metabolic, and functional CD4 T cell paralysis in the lymph node impedes tumor control

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Activating Inducible T cell Co-stimulator (ICOS) yields anti-tumor activity alone and in combination with anti-PD-1 checkpoint blockade

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Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis

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CD39 inhibition and VISTA blockade may overcome radiotherapy resistance by targeting exhausted CD8+ T cells and immunosuppressive myeloid cells

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A CSF-1R-blocking antibody/IL-10 fusion protein increases anti-tumor immunity by effectuating tumor-resident CD8+ T cells

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Membrane-localized neoantigens predict the efficacy of cancer immunotherapy

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PD-L1/PD-1 checkpoint pathway regulates hippocampal neuronal excitability and learning and memory behavior

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RORψt+CD4+ T cells promote IL-23R-mediated neuronal cell apoptosis in the central nervous system

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May 2023
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CCL19+ dendritic cells potentiate clinical benefit of anti-PD-(L)1 immunotherapy in triple-negative breast cancer

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The glycolysis/HIF-1α axis defines the inflammatory role of IL-4-primed macrophages

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The gut microbiota promotes distal tissue regeneration via RORγ+ regulatory T cell emissaries

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Targeting the mevalonate pathway suppresses ARID1A-inactivated cancers by promoting pyroptosis

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Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy

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Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment

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Targeting protein tyrosine phosphatases for CDK6-induced immunotherapy resistance

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LCN2 secreted by tissue-infiltrating neutrophils induces the ferroptosis and wasting of adipose and muscle tissues in lung cancer cachexia

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ILC3s restrict the dissemination of intestinal bacteria to safeguard liver regeneration after surgery

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IFNγ is a central node of cancer immune equilibrium

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Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy

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  DOI: 10.1126/sciimmunol.add8005
  
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Feb 2023
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Interplay between liver and blood stages of Plasmodium infection dictates malaria severity via γδ T cells and IL-17-promoted stress erythropoiesis

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Circumvention of luteolysis reveals parturition pathways in mice dependent upon innate type 2 immunity

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KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer

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Neutrophil-activating therapy for the treatment of cancer

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MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors

1
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Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy

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Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles

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Flt3- and Tie2-Cre tracing identifies regeneration in sepsis from multipotent progenitors but not hematopoietic stem cells

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Microbiota-dependent and -independent postnatal development of salivary immunity

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Immune checkpoint therapy-elicited sialylation of IgG antibodies impairs antitumorigenic type I interferon responses in hepatocellular carcinoma

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Hyaluronan driven by epithelial aPKC deficiency remodels the microenvironment and creates a vulnerability in mesenchymal colorectal cancer

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Original research: Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity

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STAT3 gain-of-function mutations connect leukemia with autoimmune disease by pathological NKG2Dhi CD8+ T cell dysregulation and accumulation

1
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Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop

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The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity

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Obesity enhances antiviral immunity in the genital mucosa through a microbiota-mediated effect on γδ T cells

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Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma

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Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy

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NOTCH induced MDSC recruitment after oHSV virotherapy in CNS cancer models modulates anti-tumor immunotherapy

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The ketone body β-hydroxybutyrate mitigates ILC2-driven airway inflammation by regulating mast cell function

1
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cir-22-0088-html.html

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Group 3 innate lymphocytes make a distinct contribution to Type 17 immunity in bladder defence

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Proinflammatory signaling in islet β cells propagates invasion of pathogenic immune cells in autoimmune diabetes

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PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment

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WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC

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Topical therapy for regression and melanoma prevention of congenital giant nevi

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Lymph node colonization induces tumor-immune tolerance to promote distant metastasis

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Immunosuppressive tumor microenvironment in Uterine Serous Carcinoma via CCL7 signal with myeloid-derived suppressor cells

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Mar 2022
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The microbial metabolite trimethylamine N-oxide promotes antitumor immunity in triple-negative breast cancer

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Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity

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Tumor-associated high endothelial venules mediate lymphocyte entry into tumors and predict response to PD-1 plus CTLA-4 combination immunotherapy

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ICAM-1-mediated adhesion is a prerequisite for exosome-induced T cell suppression

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Jan 2022
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MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells

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Virulence factors perforate the pathogen-containing vacuole to signal efferocytosis

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Opposing Effects of Granulocyte Colony-Stimulating Factor on the Initiation and Progression of Breast Cancer Bone Metastases

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1. scibot 22 Dec 2021
  
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  RRID:AB_1107780
  
  DOI: 10.1158/1541-7786.MCR-21-0243
  
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Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance

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  RRID:AB_1107780
  
  DOI: 10.1038/s41467-021-27349-7
  
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Cold exposure protects from neuroinflammation through immunologic reprogramming

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  RRID:AB_1107780
  
  DOI: 10.1016/j.cmet.2021.10.002
  
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Live Imaging of SARS-CoV-2 Infection in Mice Reveals that Neutralizing Antibodies Require Fc Function for Optimal Efficacy

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1. scibot 23 Sep 2021
  
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  RRID:AB_1107780
  
  DOI: 10.1016/j.immuni.2021.08.015
  
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Effector T cell responses unleashed by regulatory T cell ablation exacerbate oral squamous cell carcinoma

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  RRID:AB_1107780
  
  DOI: 10.1016/j.xcrm.2021.100399
  
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Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope

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  RRID:AB_1107780
  
  DOI: 10.1016/j.cell.2021.07.006
  
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Identification of a Locus in Mice that Regulates the Collateral Damage and Lethality of Virus Infection

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1. scibot 13 Aug 2021
  
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  RRID:AB_1107780
  
  DOI: 10.1016/j.celrep.2019.04.004
  
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Untitled document

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  DOI: 10.1016/j.immuni.2017.11.003
  
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  DOI: 10.1016/j.cell.2018.10.014
  
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Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1−CD8+ Tumor-Infiltrating T Cells

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1. scibot 01 Aug 2021
  
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  DOI: 10.1016/j.immuni.2018.11.014
  
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Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection

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1. scibot 31 Jul 2021
  
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  DOI: 10.1016/j.chom.2019.03.003
  
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Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells

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1. scibot 30 Jul 2021
  
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  InVivoMab rat IgG2b isotype control clone LTF-2
  
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  DOI: 10.1016/j.immuni.2018.10.009
  
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  DOI: 10.1016/j.immuni.2018.10.007
  
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T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation

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  AB_1107780
  
  DOI: 10.1016/j.cell.2018.10.008
  
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Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma

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1. scibot 30 Jul 2021
  
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  RRID:AB_1107780
  
  DOI: 10.1016/j.cell.2018.10.038
  
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