92 Matching Annotations
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    Chemoradiotherapy-induced ACKR2+ tumor cells drive CD8+ T cell senescence and cervical cancer recurrence
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    1. scibot 09 May 2024
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    sciencedirect.com/science/article/pii/S2666379124002428
  3. Apr 2024
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    IGSF8 is an innate immune checkpoint and cancer immunotherapy target
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    ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion
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    sciencedirect.com/science/article/pii/S0092867424003106
  6. Mar 2024
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    Multimodal stimulation screens reveal unique and shared genes limiting T cell fitness
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  8. Jan 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor cell–intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling
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    1. scibot 25 Jan 2024
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      DOI: 10.1126/sciadv.adi2012

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    2. scibot 23 Jan 2024
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      DOI: 10.1126/sciadv.adi2012

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    ncbi.nlm.nih.gov/pmc/articles/PMC10798567/
  10. Dec 2023
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    Reprogramming of tumor-associated macrophages via NEDD4-mediated CSF1R degradation by targeting USP18
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    sciencedirect.com/science/article/pii/S2211124723015723
  12. Nov 2023
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    A SOX9-B7x axis safeguards dedifferentiated tumor cells from immune surveillance to drive breast cancer progression
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    1. scibot 17 Nov 2023
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  14. Oct 2023
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    Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation
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    1. scibot 28 Oct 2023
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  16. Aug 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating Inducible T cell Co-stimulator (ICOS) yields anti-tumor activity alone and in combination with anti-PD-1 checkpoint blockade
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    1. scibot 26 Aug 2023
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    IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function
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    1. scibot 23 Aug 2023
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  19. 52.53.155.43 52.53.155.43
    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
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    1. scibot 17 Aug 2023
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  20. 52.53.155.43 52.53.155.43
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  21. Jul 2023
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    Lung injury induces a polarized immune response by self-antigen-specific CD4+ Foxp3+ regulatory T cells
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  23. Apr 2023
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    Dysregulated lung stroma drives emphysema exacerbation by potentiating resident lymphocytes to suppress an epithelial stem cell reservoir
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    Identification of fibrocyte cluster in tumors reveals the role in antitumor immunity by PD-L1 blockade
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      DOI: 10.1016/j.celrep.2023.112162

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  26. Mar 2023
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    Schwann Cell Insulin-like Growth Factor Receptor Type-1 Mediates Metastatic Bone Cancer Pain in Mice
    1
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    sciencedirect.com/science/article/pii/S0889159123000703
  28. Feb 2023
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    Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer
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      DOI: 10.15252/embr.202256524

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    embopress.org/doi/10.15252/embr.202256524
  30. Jan 2023
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    Neutrophil-activating therapy for the treatment of cancer
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    MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors
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    TGFBI Production by Macrophages Contributes to an Immunosuppressive Microenvironment in Ovarian Cancer
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      DOI: 10.1158/0008-5472.CAN-21-0536

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    GATA4 controls regionalization of tissue immunity and commensal-driven immunopathology
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  35. Dec 2022
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    Cancer cell-derived type I interferons instruct tumor monocyte polarization
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    sciencedirect.com/science/article/pii/S2211124722016527
  37. Nov 2022
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    CD16+ fibroblasts foster a trastuzumab-refractory microenvironment that is reversed by VAV2 inhibition
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    The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity
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    Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma
    1
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  41. Sep 2022
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    Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
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    Pathobiont-responsive Th17 cells in gut-mouth axis provoke inflammatory oral disease and are modulated by intestinal microbiome
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      DOI: 10.1016/j.celrep.2022.111314

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    sciencedirect.com/science/article/pii/S221112472201138X
  44. Aug 2022
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    Enterobacter ludwigii protects DSS-induced colitis through choline-mediated immune tolerance
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  46. May 2022
  47. www.sciencedirect.com www.sciencedirect.com
    The C5a-C5aR1 complement axis is essential for neutrophil recruitment to draining lymph nodes via high endothelial venules in cutaneous leishmaniasis
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    sciencedirect.com/science/article/pii/S2211124722005411
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    Lymph node colonization induces tumor-immune tolerance to promote distant metastasis
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      DOI: 10.1016/j.cell.2022.04.019

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    sciencedirect.com/science/article/pii/S0092867422004664
  49. Apr 2022
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    Treg tissue stability depends on lymphotoxin beta-receptor- and adenosine-receptor-driven lymphatic endothelial cell responses
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    sciencedirect.com/science/article/pii/S2211124722004880
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    Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques
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      DOI: 10.1016/j.immuni.2022.03.018

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    Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity
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  53. Mar 2022
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    AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells
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      DOI: 10.1016/j.xcrm.2022.100554

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  55. Feb 2022
  56. www.sciencedirect.com www.sciencedirect.com
    An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity
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      DOI: 10.1016/j.cell.2022.01.009

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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity
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  58. www.pnas.org www.pnas.org
    Eosinophils regulate intra-adipose axonal plasticity
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  59. www.sciencedirect.com www.sciencedirect.com
    βig-h3-structured collagen alters macrophage phenotype and function in pancreatic cancer
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    Antibody bivalency improves antiviral efficacy by inhibiting virion release independently of Fc gamma receptors
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  61. Oct 2021
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment
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  63. www.sciencedirect.com www.sciencedirect.com
    Synergistic effect of non-neutralizing antibodies and interferon-γ for cross-protection against influenza
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  64. Sep 2021
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    IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer’s disease
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  66. Aug 2021
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    The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer
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  69. Jul 2021
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    Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced Colitis
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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T cells drive negative feedback mechanisms in cancer associated fibroblasts, promoting expression of co-inhibitory ligands, CD73 and IL-27 in non-small cell lung cancer
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    Cell-autonomous inflammation of BRCA1-deficient ovarian cancers drives both tumor-intrinsic immunoreactivity and immune resistance via STING
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    A safe and effective mucosal RSV vaccine in mice consisting of RSV phosphoprotein and flagellin variant
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    Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity
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  75. Jun 2021
  76. www.cell.com www.cell.com
    Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota
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  77. May 2021
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    Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis
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    The Gut Microbiome Regulates Psychological-Stress-Induced Inflammation
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    Metabolic stress drives sympathetic neuropathy within the liver
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  81. Apr 2021
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    Human T-bet Governs Innate and Innate-like Adaptive IFN-γ Immunity against Mycobacteria
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    Chronic stress physically spares but functionally impairs innate-like invariant T cells
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  84. Mar 2021
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    Early innate and adaptive immune perturbations determine long-term severity of chronic virus and Mycobacterium tuberculosis coinfection
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      RRID: AB_1107636

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    Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer
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  87. Feb 2021
  88. elifesciences.org elifesciences.org
    IL-21/type I interferon interplay regulates neutrophil-dependent innate immune responses to Staphylococcus aureus
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      RRID:AB_1107784

      DOI: 10.7554/eLife.45501

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    Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses
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  90. www.cell.com www.cell.com
    Murine model of colonization with fungal pathogen Candida auris to explore skin tropism, host risk factors and therapeutic strategies
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      DOI: 10.1016/j.chom.2020.12.002

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    cell.com/cell-host-microbe/abstract/S1931-3128(20)30664-8
  91. Jan 2021
  92. www.sciencedirect.com www.sciencedirect.com
    Systemic Inflammation Suppresses Lymphoid Tissue Remodeling and B Cell Immunity during Concomitant Local Infection
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  93. Nov 2020
  94. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Airway Microbiota-Host Interactions Regulate Secretory Leukocyte Protease Inhibitor Levels and Influence Allergic Airway Inflammation
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      RRID:AB_1107784

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  95. Sep 2020
  96. www.sciencedirect.com www.sciencedirect.com
    Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer
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      RRID:AB_1107784

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    The Cytokine IL-17A Limits Th17 Pathogenicity via a Negative Feedback Loop Driven by Autocrine Induction of IL-24
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      RRID:AB_1107784

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    Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity
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    CD28 Regulates Metabolic Fitness for Long-Lived Plasma Cell Survival
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  100. Jan 2020
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    Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles
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    Yap1-Driven Intestinal Repair Is Controlled by Group 3 Innate Lymphoid Cells
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    High Glucose Intake Exacerbates Autoimmunity through Reactive-Oxygen-Species-Mediated TGF-β Cytokine Activation
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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epithelial NOTCH Signaling Rewires the Tumor Microenvironment of Colorectal Cancer to Drive Poor-Prognosis Subtypes and Metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC6853173/
  105. www.sciencedirect.com www.sciencedirect.com
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    Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced Colitis
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