125 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of NEK2 Promotes Chemosensitivity and Reduces KSHV-positive Primary Effusion Lymphoma Burden
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    1. scibot 11 Apr 2024
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      DOI: 10.1158/2767-9764.CRC-23-0430

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    ncbi.nlm.nih.gov/pmc/articles/PMC11003453/
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    Islet resident macrophage-derived miR-155 promotes β-cell decompensation via targeting PDX1
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    1. scibot 11 Apr 2024
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      DOI: 10.1016/j.isci.2024.109540

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    ncbi.nlm.nih.gov/pmc/articles/PMC10993184/
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    ISG12a promotes immunotherapy of HBV-associated hepatocellular carcinoma through blocking TRIM21/AKT/β-Catenin/PD-L1 axis
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    1. scibot 10 Apr 2024
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      DOI: 10.1016/j.isci.2024.109533

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    ncbi.nlm.nih.gov/pmc/articles/PMC11000115/
  5. Apr 2024
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    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
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    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114065

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    sciencedirect.com/science/article/pii/S2211124724003930
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    Oct4 controls basement membrane development during human embryogenesis
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    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.devcel.2024.03.007

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    sciencedirect.com/science/article/pii/S1534580724001758
  8. Mar 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TLR2 regulates hair follicle cycle and regeneration via BMP signaling
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    1. scibot 16 Mar 2024
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      DOI: 10.7554/eLife.89335

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    ncbi.nlm.nih.gov/pmc/articles/PMC10939499/
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    CRB1-associated retinal degeneration is dependent on bacterial translocation from the gut
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    1. scibot 07 Mar 2024
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      DOI: 10.1016/j.cell.2024.01.040

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    sciencedirect.com/science/article/pii/S0092867424001089
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    ALK upregulates POSTN and WNT signaling to drive neuroblastoma
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    sciencedirect.com/science/article/pii/S2211124724002559
  12. 52.53.155.43 52.53.155.43
    Targeting LTA4H facilitates the reshaping of the immune microenvironment mediated by CCL5 and sensitizes ovarian cancer to Cisplatin
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      DOI: 10.1007/s11427-023-2444-5

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  13. Feb 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An integrative proteomics approach identifies tyrosine kinase KIT as a therapeutic target for SPINK1-positive prostate cancer
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    1. scibot 28 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10879682/
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    Activation of the Wnt/β-catenin/CYP1B1 pathway alleviates oxidative stress and protects the blood-brain barrier under cerebral ischemia/reperfusion conditions
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    1. scibot 28 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10883507/
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    EZH2/G9a interact to mediate drug resistance in non-small-cell lung cancer by regulating the SMAD4/ERK/c-Myc signaling axis
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    1. scibot 09 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724000421
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    Gut-liver axis calibrates intestinal stem cell fitness
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    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.cell.2024.01.001

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    sciencedirect.com/science/article/pii/S0092867424000035
  18. Jan 2024
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    A gut microbiota-bile acid axis promotes intestinal homeostasis upon aspirin-mediated damage
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    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.chom.2023.12.015

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    sciencedirect.com/science/article/pii/S1931312823005103
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    miRNA-194-3p represses NF-κB in gliomas to attenuate iPSC genes and proneural to mesenchymal transition.
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    1. scibot 18 Jan 2024
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      DOI: 10.1016/j.isci.2023.108650

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    ncbi.nlm.nih.gov/pmc/articles/PMC10788216/
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    Mechanism of GW117 antidepressant action: melatonin receptor-mediated regulation of sleep rhythm
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      DOI: 10.1016/j.ejphar.2023.176299

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    sciencedirect.com/science/article/pii/S0014299923008130
  22. Dec 2023
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    Extracellular carriers control lipid-dependent secretion, delivery, and activity of WNT morphogens
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    1. scibot 29 Dec 2023
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    sciencedirect.com/science/article/pii/S1534580723006482
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    AID-induced CXCL12 upregulation enhances castration-resistant prostate cancer cell metastasis by stabilizing β-catenin expression
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    1. scibot 21 Dec 2023
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      DOI: 10.1016/j.isci.2023.108523

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    sciencedirect.com/science/article/pii/S2589004223026007
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    ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors
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      DOI: 10.1016/j.celrep.2023.113541

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    sciencedirect.com/science/article/pii/S221112472301553X
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    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
    1
    1. scibot 16 Dec 2023
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      DOI: 10.1016/j.ccell.2023.11.010

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    sciencedirect.com/science/article/pii/S1535610823004014
  27. Nov 2023
  28. www.sciencedirect.com www.sciencedirect.com
    CLMP is a tumor suppressor that determines all-trans retinoic acid response in colorectal cancer
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    1. scibot 17 Nov 2023
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      DOI: 10.1016/j.devcel.2023.10.006

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    sciencedirect.com/science/article/pii/S1534580723005257
  29. Sep 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of AKT induces EZH2-mediated β-catenin trimethylation in colorectal cancer
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      DOI: 10.1016/j.isci.2023.107630

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    ncbi.nlm.nih.gov/pmc/articles/PMC10475482/
  31. Aug 2023
  32. 52.53.155.43 52.53.155.43
    Synergy of 5-aminolevulinate supplement and CX3CR1 suppression promotes liver regeneration via elevated IGF-1 signaling
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    52.53.155.43/1bbe45cf5b4e78c7829bbc8558904ff45b580eb3/PIIS2211124723009956-html.html
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    Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3
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      DOI: 10.1016/j.chembiol.2023.07.006

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    sciencedirect.com/science/article/pii/S2451945623002337
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-Catenin immunocytochemical reactivity in cervicovaginal smears during regular menstrual cycles
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      DOI: 10.1515/abm-2020-0027

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    ncbi.nlm.nih.gov/pmc/articles/PMC10373400/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tissue tension permits β-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells
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      DOI: 10.1101/2023.07.14.549074

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    ncbi.nlm.nih.gov/pmc/articles/PMC10370032/
  36. Jul 2023
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    Stromal-induced epithelial-mesenchymal transition induces targetable drug resistance in acute lymphoblastic leukemia
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    sciencedirect.com/science/article/pii/S221112472300815X
  38. Jun 2023
  39. 52.53.155.43 52.53.155.43
    bqad096-html.html
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      DOI: 10.1210/endocr/bqad096

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    Peroxisome proliferator activated receptor-γ in osteoblasts controls bone formation and fat mass by regulating sclerostin expression
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    sciencedirect.com/science/article/pii/S2589004223010763
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    Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration
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      DOI: 10.1016/j.celrep.2023.112647

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    sciencedirect.com/science/article/pii/S2211124723006587
  42. May 2023
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lacking ARHGAP25 mitigates the symptoms of autoantibody-induced arthritis in mice
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      DOI: 10.3389/fimmu.2023.1182278

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    ncbi.nlm.nih.gov/pmc/articles/PMC10208528/
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    A Wnt-induced lncRNA-DGCR5 splicing switch drives tumor-promoting inflammation in esophageal squamous cell carcinoma
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    sciencedirect.com/science/article/pii/S2211124723005533
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    Cross-activation of FGF, NODAL, and WNT pathways constrains BMP-signaling-mediated induction of the totipotent state in mouse embryonic stem cells
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    sciencedirect.com/science/article/pii/S2211124723004497
  46. Apr 2023
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    Casein kinase 1α is required to maintain murine hypothalamic POMC expression
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      DOI: 10.1016/j.isci.2023.106670

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    sciencedirect.com/science/article/pii/S2589004223007472
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    Phosphodiesterase type 10A inhibitor attenuates lung fibrosis by targeting myofibroblast activation
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    sciencedirect.com/science/article/pii/S2589004223006636
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    Cell-to-cell variability in Myc dynamics drives transcriptional heterogeneity in cancer cells
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      DOI: 10.1016/j.celrep.2023.112401

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    sciencedirect.com/science/article/pii/S2211124723004126
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    Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities
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      DOI: 10.7554/eLife.78629

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    ncbi.nlm.nih.gov/pmc/articles/PMC10069870/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adiponectin-mediated promotion of CD44 suppresses diabetic vascular inflammatory effects
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    ncbi.nlm.nih.gov/pmc/articles/PMC10067764/
  52. Mar 2023
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suppression of preadipocyte determination by SOX4 limits white adipocyte hyperplasia in obesity
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    Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer
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    Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders
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    CDK1 bridges NF-κB and β-catenin signaling in response to H. pylori infection in gastric tumorigenesis
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  58. Dec 2022
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    Linc-ROR drive adriamycin resistance by targeting AP-2α/Wnt/β-catenin axis in hepatocellular carcinoma
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    Interferon-dependent SLC14A1+ cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer
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    PERIOD 2 Regulates Low Dose Radioprotection via PER2/pGSK3β/β-Catenin/Per2 Loop
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  62. Sep 2022
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    Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development
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    Disruption of beta-catenin dependent Wnt signaling in colon cancer cells remodels the microenvironment to promote tumor invasion
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    Effects of Wnt-β-catenin signaling and sclerostin on the phenotypes of rat pheochromocytoma PC12 cells
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  66. Aug 2022
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    Glycosphingolipids are mediators of cancer plasticity through independent signaling pathways
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  68. Jul 2022
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    Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth
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    Potassium channel Kir4.1 regulates oligodendrocyte differentiation via intracellular pH regulation
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  71. Jun 2022
  72. aacrjournals.org aacrjournals.org
    NR2F1 is a barrier to dissemination of early stage breast cancer cells.
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  73. academic.oup.com academic.oup.com
    Jumonji domain-containing protein-3 (JMJD3/Kdm6b) is critical for normal ovarian function and female fertility
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  74. Apr 2022
  75. journals.physiology.org journals.physiology.org
    Hypoxia-inducible factor protects against acute kidney injury via the Wnt/β-catenin signaling pathway
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    Brown adipose tissue involution associated with progressive restriction in progenitor competence
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  77. Mar 2022
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    Delicate regulation of IL-1β-mediated inflammation by cyclophilin A
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  79. Feb 2022
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    Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity
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    Wnt7a inhibits transformed cell proliferation while promoting migration and invasion in non-small cell lung cancer
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    Radiation induces epithelial to mesenchymal transition via upregulation of PD-L1 in nasopharyngeal carcinoma cell
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  83. Dec 2021
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    Translational and post-translational control of human naïve versus primed pluripotency
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    Low-intensity pulsed ultrasound-generated singlet oxygen induces telomere damage leading to glioma stem cell awakening from quiescence
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    Impact of Prematurity on the Buccal Epithelial Cells of the Neonates via Wnt/Beta-Catenin Signaling Pathway and Apoptosis
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    Liver sphingomyelin synthase 1 deficiency causes steatosis, steatohepatitis, fibrosis, and tumorigenesis: An effect of glucosylceramide accumulation
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    A new murine esophageal organoid culture method and organoid-based model of esophageal squamous cell neoplasia
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  89. Nov 2021
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    Chronic lithium administration in a mouse model for Krabbe disease
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    Myopalladin knockout mice develop cardiac dilation and show a maladaptive response to mechanical pressure overload
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    Spindle and kinetochore-associated complex subunit 3 (SKA3) promotes stem cell-like properties of hepatocellular carcinoma cells through activating Notch signaling pathway
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  93. Oct 2021
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    ABL allosteric inhibitors synergize with statins to enhance apoptosis of metastatic lung cancer cells
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    miR-103-3p targets Ndel1 to regulate neural stem cell proliferation and differentiation
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  96. Sep 2021
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    Doxazosin and erlotinib have anticancer effects in the endometrial cancer cell and important roles in ERα and Wnt/β-catenin signaling pathways
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  98. Aug 2021
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    The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway
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    Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy
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    β-Catenin Directs Long-Chain Fatty Acid Catabolism in the Osteoblasts of Male Mice
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    Genomic Function of Estrogen Receptor Beta In Endometriosis
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  103. Jul 2021
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    TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells
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    Extracellular domain shedding of the ALK receptor mediates neuroblastoma cell migration
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    Vangl2 limits chaperone-mediated autophagy to balance osteogenic differentiation in mesenchymal stem cells
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  108. Jun 2021
  109. www.sciencedirect.com www.sciencedirect.com
    Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
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      DOI: 10.1016/j.celrep.2021.109291

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    A genome-wide library of MADM mice for single-cell genetic mosaic analysis
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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction
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  112. May 2021
  113. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Loss of interleukin-10 receptor disrupts intestinal epithelial cell proliferation and skews differentiation towards the goblet cell fate
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  114. www.sciencedirect.com www.sciencedirect.com
    PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR
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    Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway
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  116. www.sciencedirect.com www.sciencedirect.com
    Mechanical Tension Promotes Formation of Gastrulation-like Nodes and Patterns Mesoderm Specification in Human Embryonic Stem Cells
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    AP-2β/KCTD1 Control Distal Nephron Differentiation and Protect against Renal Fibrosis
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    Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy
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  120. Apr 2021
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    MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism
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  122. Mar 2021
  123. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  124. Feb 2021
  125. academic.oup.com academic.oup.com
    Myeloid-derived Growth Factor Promotes Intestinal Glucagon-like Peptide-1 Production in Male Mice with Type 2 Diabetes
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  126. www.cell.com www.cell.com
    Therapy-Induced Evolution of Human Lung Cancer Revealed by Single-Cell RNA Sequencing
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  127. Dec 2020
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RSPO3 is a marker candidate for predicting tumor aggressiveness in ovarian cancer
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  129. Nov 2020
  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In utero exposure to maternal diabetes impairs nephron progenitor differentiation
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  131. Oct 2020
  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  134. Sep 2020
  135. www.cell.com www.cell.com
    Development of Potent, Selective Surrogate WNT Molecules and Their Application in Defining Frizzled Requirements
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  136. www.sciencedirect.com www.sciencedirect.com
    Engineered Illumination Devices for Optogenetic Control of Cellular Signaling Dynamics
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    sciencedirect.com/science/article/pii/S2211124720307178
  137. www.sciencedirect.com www.sciencedirect.com
    Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation
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      DOI: 10.1016/j.celrep.2019.12.075

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    GDE2-Dependent Activation of Canonical Wnt Signaling in Neurons Regulates Oligodendrocyte Maturation
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      DOI: 10.1016/j.celrep.2020.107540

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  139. www.sciencedirect.com www.sciencedirect.com
    Assembly of Peripheral Actomyosin Bundles in Epithelial Cells Is Dependent on the CaMKK2/AMPK Pathway
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  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination
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  141. stke.sciencemag.org stke.sciencemag.org
    Blocking EGFR palmitoylation suppresses PI3K signaling and mutant KRAS lung tumorigenesis
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      β-catenin

      DOI: 10.1126/scisignal.aax2364

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  142. journals.plos.org journals.plos.org
    Testisin/Prss21 deficiency causes increased vascular permeability and a hemorrhagic phenotype during luteal angiogenesis
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      rabbit anti-β-catenin

      DOI: 10.1371/journal.pone.0234407

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  143. Jan 2020
  144. elifesciences.org elifesciences.org
    FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy
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  145. www.sciencedirect.com www.sciencedirect.com
    Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination
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  146. www.sciencedirect.com www.sciencedirect.com
    Identification of a Small Compound Targeting PKM2-Regulated Signaling Using 2D Gel Electrophoresis-Based Proteome-wide CETSA
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    miR-29a/b1 Inhibits Hair Follicle Stem Cell Lineage Progression by Spatiotemporally Suppressing WNT and BMP Signaling
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      DOI: 10.1016/j.celrep.2019.10.062

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  148. www.sciencedirect.com www.sciencedirect.com
    High RhCG expression predicts poor survival and promotes migration and proliferation of gastric cancer via keeping intracellular alkaline
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  149. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.stem.2019.04.015

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  150. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Decorin promotes proliferation and migration of ORS keratinocytes and maintains hair anagen in mice
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      DOI: 10.1111/exd.13770

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  152. Nov 2018
  153. www.sciencedirect.com www.sciencedirect.com
    Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM
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  154. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Chemoresistance of cancer floating cells is independent of their ability to form 3D structures: Implications for anticancer drug screening
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    Targeting Epigenetic Crosstalk as a Therapeutic Strategy for EZH2-Aberrant Solid Tumors
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    Ouabain increases neuronal branching in hippocampus and improves spatial memory
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    Spatial Fold Change of FGF Signaling Encodes Positional Information for Segmental Determination in Zebrafish
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      RRID:AB_11127855

      Curator: @evieth

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  158. www.sciencedirect.com www.sciencedirect.com
    Regulation of Epithelial Plasticity Determines Metastatic Organotropism in Pancreatic Cancer
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    sciencedirect.com/science/article/pii/S1534580718304180
  159. www.sciencedirect.com www.sciencedirect.com
    EMT Subtype Influences Epithelial Plasticity and Mode of Cell Migration
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    1. scibot 05 Nov 2018
      RRID:AB_11127855

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    sciencedirect.com/science/article/pii/S1534580718304209
  160. academic.oup.com academic.oup.com
    Targeted Disruption of YAP and TAZ Impairs the Maintenance of the Adrenal Cortex
    1
    1. scibot 05 Nov 2018
      AB_11127855

      Curator: @evieth

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      (Cell Signaling Technology Cat# 8480, RRID:AB_11127855)

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  161. Nov 2017
  162. www.sciencedirect.com www.sciencedirect.com
    Complement Component 3 Adapts the Cerebrospinal Fluid for Leptomeningeal Metastasis
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    1. scibot 08 Nov 2017
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0092867417302404
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    TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells
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    1. scibot 08 Nov 2017
      AB_11127855

      Curator: @kaitlinsung

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      RRID:AB_11127855 RRIDCUR:Missing RRIDCUR:Unresolved
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