60 Matching Annotations
  1. Sep 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Landscape of Exhausted Virus-Specific CD8 T Cells in Chronic LCMV Infection
    1
    1. scibot 25 Sep 2024
      RRID:AB_11147170

      DOI: 10.1016/j.celrep.2020.108078

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    sciencedirect.com/science/article/pii/S2211124720310639
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immune isolation-enabled nanoencapsulation of donor T cells: a promising strategy for mitigating GVHD and treating AML in preclinical models
    1
    1. scibot 12 Sep 2024
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      DOI: 10.1136/jitc-2023-008663

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    ncbi.nlm.nih.gov/pmc/articles/PMC11381671/
  4. Aug 2024
  5. www.sciencedirect.com www.sciencedirect.com
    PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8+ T cell ferroptosis
    1
    1. scibot 29 Aug 2024
      RRID:AB_11147170

      DOI: 10.1016/j.immuni.2024.08.003

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    sciencedirect.com/science/article/pii/S1074761324003765
  6. www.sciencedirect.com www.sciencedirect.com
    LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity
    1
    1. scibot 20 Aug 2024
      RRID:AB_11147170

      DOI: 10.1016/j.cell.2024.07.016

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    sciencedirect.com/science/article/pii/S0092867424007761
  7. Jul 2024
  8. www.cell.com www.cell.com
    Fecal microbiota transplantation improves anti-PD-1 inhibitor efficacy in unresectable or metastatic solid cancers refractory to anti-PD-1 inhibitor
    1
    1. scibot 30 Jul 2024
      RRID:AB_11147170

      DOI: 10.1016/j.chom.2024.06.010

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    cell.com/cell-host-microbe/abstract/S1931-3128(24)00228-2
  9. www.biorxiv.org www.biorxiv.org
    Inhibition of CD226 Co-Stimulation Suppresses Diabetes Development in the NOD Mouse by Augmenting Tregs and Diminishing Effector T Cell Function
    1
    1. scibot 23 Jul 2024
      RRID:AB_11147170

      DOI: 10.1101/2024.07.16.603756

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    biorxiv.org/content/10.1101/2024.07.16.603756v1
  10. www.sciencedirect.com www.sciencedirect.com
    PARP11 inhibition inactivates tumor-infiltrating regulatory T cells and improves the efficacy of immunotherapies
    1
    1. scibot 17 Jul 2024
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      DOI: 10.1016/j.xcrm.2024.101649

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    sciencedirect.com/science/article/pii/S266637912400363X
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    A Th17 cell-intrinsic glutathione/mitochondrial-IL-22 axis protects against intestinal inflammation
    1
    1. scibot 12 Jul 2024
      RRID:AB_11147170

      DOI: 10.1016/j.cmet.2024.06.010

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    sciencedirect.com/science/article/pii/S1550413124002353
  12. Jun 2024
  13. www.sciencedirect.com www.sciencedirect.com
    Clonal hematopoiesis driven by mutated DNMT3A promotes inflammatory bone loss
    1
    1. scibot 05 Jun 2024
      RRID:AB_11147170

      DOI: 10.1016/j.cell.2024.05.003

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    sciencedirect.com/science/article/pii/S0092867424004926
  14. May 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Metabolic coordination between skin epithelium and type 17 immunity sustains chronic skin inflammation
    1
    1. scibot 21 May 2024
      RRID:AB_11147170

      DOI: 10.1016/j.immuni.2024.04.022

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    sciencedirect.com/science/article/pii/S1074761324002279
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    Transient hydroxycholesterol treatment restrains TCR signaling to promote long-term immunity
    1
    1. scibot 17 May 2024
      RRID:AB_11147170

      DOI: 10.1016/j.chembiol.2024.04.005

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    sciencedirect.com/science/article/pii/S2451945624001673
  17. Apr 2024
  18. aacrjournals.org aacrjournals.org
    Spatial and temporal mapping of breast cancer lung metastases identify TREM2 macrophages as regulators of the metastatic boundary
    1
    1. scibot 19 Apr 2024
      RRID:AB_11147170

      DOI: 10.1158/2159-8290.CD-23-0299

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    aacrjournals.org/cancerdiscovery/article/13/12/2610/731625/Spatial-and-Temporal-Mapping-of-Breast-Cancer-Lung
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    IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling
    1
    1. scibot 11 Apr 2024
      RRID:AB_11147170

      DOI: 10.1016/j.celrep.2024.114088

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    sciencedirect.com/science/article/pii/S2211124724004169
  20. Feb 2024
  21. www.sciencedirect.com www.sciencedirect.com
    UFL1 ablation in T cells suppresses PD-1 UFMylation to enhance anti-tumor immunity
    1
    1. scibot 28 Feb 2024
      RRID:AB_11147170

      DOI: 10.1016/j.molcel.2024.01.024

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    sciencedirect.com/science/article/pii/S1097276524000911
  22. www.sciencedirect.com www.sciencedirect.com
    Suppression of the METTL3-m6A-integrin β1 axis by extracellular acidification impairs T cell infiltration and antitumor activity
    2
    1. scibot 21 Feb 2024
      RRID:AB_11147170

      DOI: 10.1016/j.celrep.2024.113796

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    2. scibot 21 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113796

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    sciencedirect.com/science/article/pii/S2211124724001244
  23. www.sciencedirect.com www.sciencedirect.com
    Stem-like progenitor and terminally differentiated TFH-like CD4+ T cell exhaustion in the tumor microenvironment
    1
    1. scibot 16 Feb 2024
      RRID:AB_11147170

      DOI: 10.1016/j.celrep.2024.113797

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    sciencedirect.com/science/article/pii/S2211124724001256
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    An anti-CD19/CTLA-4 switch improves efficacy and selectivity of CAR T cells targeting CD80/86-upregulated DLBCL
    1
    1. scibot 14 Feb 2024
      RRID:AB_11147170

      DOI: 10.1016/j.xcrm.2024.101421

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    sciencedirect.com/science/article/pii/S2666379124000442
  25. www.sciencedirect.com www.sciencedirect.com
    Tumor-secreted FGF21 acts as an immune suppressor by rewiring cholesterol metabolism of CD8+T cells
    1
    1. scibot 06 Feb 2024
      RRID:AB_11147170

      DOI: 10.1016/j.cmet.2024.01.005

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    sciencedirect.com/science/article/pii/S1550413124000068
  26. Dec 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure
    1
    1. scibot 17 Dec 2023
      RRID:AB_11147170

      DOI: 10.1016/j.immuni.2023.11.005

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    sciencedirect.com/science/article/pii/S1074761323004879
  28. 52.53.155.43 52.53.155.43
    cd-23-0299-html.html
    1
    1. scibot 01 Dec 2023
      RRID:AB_11147170

      DOI: 10.1158/2159-8290.cd-23-0299

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    52.53.155.43/2b6c279d82b7a0e0d491057f5790a1189e93077e/cd-23-0299-html.html
  29. Nov 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Five Inhibitory Receptors Display Distinct Vesicular Distributions in Murine T Cells
    1
    1. scibot 18 Nov 2023
      RRID:AB_11147170

      DOI: 10.3390/cells12212558

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    ncbi.nlm.nih.gov/pmc/articles/PMC10649679/
  31. Sep 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Ablation of ERO1A induces lethal endoplasmic reticulum stress responses and immunogenic cell death to activate anti-tumor immunity
    1
    1. scibot 30 Sep 2023
      RRID:AB_11147170

      DOI: 10.1016/j.xcrm.2023.101206

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    sciencedirect.com/science/article/pii/S2666379123003737
  33. Aug 2023
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protocol for the isolation of mouse senescence-associated CD4+ T cells using flow cytometry and functional assays
    1
    1. scibot 10 Aug 2023
      RRID:AB_11147170

      DOI: 10.1016/j.xpro.2023.102472

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    ncbi.nlm.nih.gov/pmc/articles/PMC10400959/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Five inhibitory receptors display distinct vesicular distributions in T cells
    1
    1. scibot 03 Aug 2023
      RRID:AB_11147170

      DOI: 10.1101/2023.07.21.550019

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    ncbi.nlm.nih.gov/pmc/articles/PMC10370166/
  36. Jul 2023
  37. www.sciencedirect.com www.sciencedirect.com
    QUAS-R: An SLC1A5-mediated glutamine uptake assay with single-cell resolution reveals metabolic heterogeneity with immune populations
    1
    1. scibot 21 Jul 2023
      RRID:AB_11147170

      DOI: 10.1016/j.celrep.2023.112828

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    sciencedirect.com/science/article/pii/S2211124723008392
  38. Jun 2023
  39. www.sciencedirect.com www.sciencedirect.com
    The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells
    1
    1. scibot 23 Jun 2023
      RRID:AB_11147170

      DOI: 10.1016/j.immuni.2023.05.008

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    sciencedirect.com/science/article/pii/S107476132300225X
  40. www.sciencedirect.com www.sciencedirect.com
    Distinct bidirectional regulation of LFA1 and α4β7 by Rap1 and integrin adaptors in T cells under shear flow
    1
    1. scibot 03 Jun 2023
      RRID:AB_11147170

      DOI: 10.1016/j.celrep.2023.112580

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    sciencedirect.com/science/article/pii/S2211124723005910
  41. May 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Exhaustion-associated cholesterol deficiency dampens the cytotoxic arm of antitumor immunity
    1
    1. scibot 27 May 2023
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      DOI: 10.1016/j.ccell.2023.04.016

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    sciencedirect.com/science/article/pii/S1535610823001423
  43. www.sciencedirect.com www.sciencedirect.com
    Asymmetric cell division safeguards memory CD8 T cell development
    1
    1. scibot 13 May 2023
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      DOI: 10.1016/j.celrep.2023.112468

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    sciencedirect.com/science/article/pii/S2211124723004795
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    cis-B7:CD28 interactions at invaginated synaptic membranes provide CD28 co-stimulation and promote CD8+ T cell function and anti-tumor immunity
    1
    1. scibot 11 May 2023
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      DOI: 10.1016/j.immuni.2023.04.005

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    sciencedirect.com/science/article/pii/S1074761323001735
  45. www.sciencedirect.com www.sciencedirect.com
    Myeloid-derived suppressor cells deficient in cholesterol biosynthesis promote tumor immune evasion
    1
    1. scibot 06 May 2023
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      DOI: 10.1016/j.canlet.2023.216208

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    sciencedirect.com/science/article/pii/S0304383523001593
  46. Mar 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Galectin-3 expression in donor T cells reduces GvHD severity and lethality after allogeneic hematopoietic cell transplantation
    1
    1. scibot 16 Mar 2023
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      DOI: 10.1016/j.celrep.2023.112250

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    sciencedirect.com/science/article/pii/S2211124723002619
  48. www.sciencedirect.com www.sciencedirect.com
    Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions
    1
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      DOI: 10.1016/j.celrep.2023.112153

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    sciencedirect.com/science/article/pii/S221112472300164X
  49. Jan 2023
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy
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    1. scibot 07 Jan 2023
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      DOI: 10.1158/2159-8290.CD-21-0003

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    ncbi.nlm.nih.gov/pmc/articles/PMC9401506/
  51. Nov 2022
  52. www.sciencedirect.com www.sciencedirect.com
    Chronic type I interferon signaling promotes lipid-peroxidation-driven terminal CD8+ T cell exhaustion and curtails anti-PD-1 efficacy
    1
    1. scibot 16 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111647

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    sciencedirect.com/science/article/pii/S2211124722015182
  53. Sep 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Protocol to isolate and enrich mouse splenic naive CD4+ T cells for in vitro CD4+CD8αα+ cell induction
    1
    1. scibot 28 Sep 2022
      RRID:AB_11147170

      DOI: 10.1016/j.xpro.2022.101728

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    sciencedirect.com/science/article/pii/S2666166722006086
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    cis interaction of CD153 with TCR/CD3 is crucial for the pathogenic activation of senescence-associated T cells
    1
    1. scibot 21 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111373

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    sciencedirect.com/science/article/pii/S2211124722012050
  56. Aug 2022
  57. www.sciencedirect.com www.sciencedirect.com
    Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism, microbiota, and T cell-induced inflammation
    1
    1. scibot 27 Aug 2022
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      DOI: 10.1016/j.cmet.2022.08.003

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    sciencedirect.com/science/article/pii/S1550413122003461
  58. www.sciencedirect.com www.sciencedirect.com
    Succinate uptake by T cells suppresses their effector function via inhibition of mitochondrial glucose oxidation
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    1. scibot 23 Aug 2022
      RRID:AB_11147170

      DOI: 10.1016/j.celrep.2022.111193

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  59. Jun 2022
  60. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence
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      RRID:AB_11147170

      DOI: 10.1016/j.ccell.2022.06.001

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    sciencedirect.com/science/article/pii/S1535610822002318
  61. Apr 2022
  62. www.sciencedirect.com www.sciencedirect.com
    Binding of LAG-3 to stable peptide-MHC class II limits T cell function and suppresses autoimmunity and anti-cancer immunity
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    1. scibot 13 Apr 2022
      RRID:AB_11147170

      DOI: 10.1016/j.immuni.2022.03.013

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  63. www.sciencedirect.com www.sciencedirect.com
    Microbiota-dependent activation of the myeloid calcineurin-NFAT pathway inhibits B7H3- and B7H4-dependent anti-tumor immunity in colorectal cancer
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    sciencedirect.com/science/article/pii/S1074761322001315
  64. Mar 2022
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intracellular metabolic adaptation of intraepithelial CD4+CD8αα+ T lymphocytes
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    1. scibot 23 Mar 2022
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      DOI: 10.1016/j.isci.2022.104021

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  66. www.sciencedirect.com www.sciencedirect.com
    A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy
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      RRID:AB_11147170

      DOI: 10.1016/j.cmet.2022.02.009

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    sciencedirect.com/science/article/pii/S1550413122000535
  67. Jan 2022
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Bivalent Nanoparticle Vaccine Exhibits Potent Cross-protection against the Variants of SARS-CoV-2
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      DOI: 10.1016/j.celrep.2021.110256

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  69. Dec 2021
  70. www.sciencedirect.com www.sciencedirect.com
    Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T cells influence effector potential
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      RRID:AB_11147170

      DOI: 10.1016/j.celrep.2021.110064

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    sciencedirect.com/science/article/pii/S2211124721015503
  71. Nov 2021
  72. www.sciencedirect.com www.sciencedirect.com
    Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis
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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function
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      DOI: 10.7554/eLife.67476

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  74. Sep 2021
  75. www.sciencedirect.com www.sciencedirect.com
    A Cre-driven allele-conditioning line to interrogate CD4+ conventional T cells
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      DOI: 10.1016/j.immuni.2021.08.029

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  76. Jul 2021
  77. www.sciencedirect.com www.sciencedirect.com
    Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness
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    1. scibot 28 Jul 2021
      Ultra-LEAF Purified anti-mouse CD28

      DOI: 10.1016/j.immuni.2019.03.005

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    sciencedirect.com/science/article/pii/S1074761319300950
  78. Apr 2021
  79. www.sciencedirect.com www.sciencedirect.com
    UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability
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    1. scibot 15 Apr 2021
      RRID:AB_11147170

      DOI: 10.1016/j.celrep.2021.108966

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    sciencedirect.com/science/article/pii/S2211124721002801
  80. Mar 2021
  81. www.sciencedirect.com www.sciencedirect.com
    Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function
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    1. scibot 10 Mar 2021
      RRID:AB_11147170

      DOI: 10.1016/j.celrep.2021.108831

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    sciencedirect.com/science/article/pii/S2211124721001455
  82. Dec 2020
  83. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses
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    1. scibot 07 Dec 2020
      RRID:AB_11147170

      DOI: 10.1016/j.immuni.2020.11.015

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    pubmed.ncbi.nlm.nih.gov/33275896/
  84. Sep 2020
  85. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Heparin affects the induction of regulatory T cells independent of anticoagulant activity and suppresses the allogeneic immune responses
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      AB_11147170

      DOI: 10.1111/cei.13480

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    onlinelibrary.wiley.com/doi/10.1111/cei.13480
  86. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    CD49a Regulates Cutaneous Resident Memory CD8+ T Cell Persistence and Response
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    1. scibot 16 Sep 2020
      RRID:AB_11147170

      DOI: 10.1016/j.celrep.2020.108085

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    pubmed.ncbi.nlm.nih.gov/32877667/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms
    1
    1. scibot 13 Sep 2020
      RRID:AB_11147170

      DOI: 10.1016/j.immuni.2020.04.014

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    ncbi.nlm.nih.gov/pmc/articles/PMC8360766/
  88. Jan 2020
  89. www.cell.com www.cell.com
    STAT3 Activation-Induced Fatty Acid Oxidation in CD8+ T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth
    1
    1. scibot 13 Jan 2020
      RRID:AB_11147170

      DOI: 10.1016/j.cmet.2019.10.013

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    cell.com/cell-metabolism/fulltext/S1550-4131(19)30604-7
  90. www.sciencedirect.com www.sciencedirect.com
    Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells
    1
    1. scibot 13 Jan 2020
      RRID:AB_11147170

      DOI: 10.1016/j.cell.2019.07.044

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    sciencedirect.com/science/article/pii/S009286741930844X
  91. Nov 2018
  92. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S2211124718310854