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Human TDP-43 expression worsens FTD-related phenotypes in progranulin-insufficient mice

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1. scibot 15 Jun 2026
  
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  RRID:AB_11182943
  
  DOI: 10.1016/j.nbd.2026.107475
  
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sciencedirect.com/science/article/pii/S0969996126002202
Mar 2026
www.sciencedirect.com www.sciencedirect.com

Targeting PGAM5-driven mitochondrial integrated stress response slows ALS progression across subtypes

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1. scibot 13 Mar 2026
  
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  RRID:AB_11182943
  
  DOI: 10.1016/j.neuron.2026.02.003
  
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sciencedirect.com/science/article/pii/S0896627326000863
Jan 2026
www.sciencedirect.com www.sciencedirect.com

Aberrant nuclear pore complex degradation contributes to neurodegeneration in VCP disease

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1. scibot 06 Jan 2026
  
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  RRID:AB_11182943
  
  DOI: 10.1016/j.neuron.2025.11.017
  
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sciencedirect.com/science/article/pii/S0896627325008906
Aug 2025
onlinelibrary.wiley.com onlinelibrary.wiley.com

A Longitudinal Study of Sex Differences in a TDP-43 Mouse Model Reveals STI1 Regulation of TDP-43 Proteinopathy and Motor Deficits

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1. scibot 27 Aug 2025
  
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  RRID:AB_11182943
  
  DOI: 10.1111/jnc.70204
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.70204
Apr 2024
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KCNJ2 inhibition mitigates mechanical injury in a human brain organoid model of traumatic brain injury

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1. scibot 05 Apr 2024
  
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  RRID:AB_11182943
  
  DOI: 10.1016/j.stem.2024.03.004
  
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sciencedirect.com/science/article/pii/S1934590924000857
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genetic ablation of Sarm1 attenuates expression and mislocalization of phosphorylated TDP-43 after mouse repetitive traumatic brain injury

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1. scibot 22 Dec 2023
  
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  RRID:AB_11182943
  
  DOI: 10.1186/s40478-023-01709-4
  
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2. scibot 22 Dec 2023
  
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  RRID:AB_11182943
  
  DOI: 10.1186/s40478-023-01709-4
  
  Resource: (Proteintech Cat# 22309-1-AP, RRID:AB_11182943)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10731794/
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

TTBK1 and CK1 inhibitors restore TDP-43 pathology and avoid disease propagation in lymphoblast from Alzheimer’s disease patients

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1. scibot 26 Aug 2023
  
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  AB_11182943
  
  DOI: 10.3389/fnmol.2023.1243277
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10445132/
Feb 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PIKFYVE inhibition mitigates disease in models of diverse forms of ALS

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1. scibot 09 Feb 2023
  
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  RRID:AB_11182943
  
  DOI: 10.1016/j.cell.2023.01.005
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10062012/
Jul 2021
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mouse closed head traumatic brain injury replicates the histological tau pathology pattern of human disease: characterization of a novel model and systematic review of the literature

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1. scibot 02 Jul 2021
  
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  RRID:AB_11182943
  
  DOI: 10.1186/s40478-021-01220-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8243463/