81 Matching Annotations
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    The E3 ligase RNF32 controls the IκB kinase complex and NF-κB signaling in intestinal stem cells
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  3. Oct 2025
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    Vitamin C conveys geroprotection on primate ovaries
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    Sensory neurons drive pancreatic cancer progression through glutamatergic neuron-cancer pseudo-synapses
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    GALNT7 stratifies dMMR/MSI colorectal cancer into distinct molecular subsets associated with prognosis and PD-L1 expression
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  8. Jun 2025
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    DMXL1 promotes recruitment of V1-ATPase to lysosomes upon TRPML1 activation
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    Senescence-resistant human mesenchymal progenitor cells counter aging in primates
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    Downregulation of cGAS/STING expression in tumor cells by cancer-associated fibroblasts in colorectal cancer
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    DSCC1 restrains 53BP1/RIF1 signaling at DNA double-strand breaks to promote homologous recombination repair
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    Cdk6’s functions are critically regulated by its unique C-terminus
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    Spatial transcriptomic landscape unveils immunoglobin-associated senescence as a hallmark of aging
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    Epstein-Barr virus induces host shutoff extensively via BGLF5-independent mechanisms
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    Leishmania infantum exploits the anti-ferroptosis effects of Nrf2 to escape cell death in macrophages
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    Adaptive changes in group-II metabotropic glutamate receptors underlie the deficit in recognition memory induced by methamphetamine in mice
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  28. Mar 2024
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    Non-random spatial organization of telomere varies during the cell cycle and requires LAP2 and BAF
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    The relevance between abnormally elevated serum ceramide and cognitive impairment in Alzheimer’s disease model mice and its mechanism
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    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
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    MMP-2-mediated Scube2 degradation promotes blood–brain barrier disruption by blocking the interaction between astrocytes and endothelial cells via inhibiting Sonic hedgehog pathway during early cerebral ischemia
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    Hepatic Huwe1 loss protects mice from non-alcoholic fatty liver disease through lipid metabolic rewiring
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    Pannexin-1 opening in neuronal edema causes cell death but also leads to protection via increased microglia contacts
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    A split-luciferase lysate-based approach to identify small-molecule modulators of phosphatase subunit interactions
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    A chimeric human/dog-DNA vaccine against CSPG4 induces immunity with therapeutic potential in comparative preclinical models of osteosarcoma
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    Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal
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    LIN28 and histone H3K4 methylase induce TLR4 to generate tumor-initiating stem-like cells
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    Resurrection of endogenous retroviruses during aging reinforces senescence
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    Extracellular vesicles from thyroid cancer harbor a functional machinery involved in extracellular matrix remodeling
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    Structure of the rabies virus glycoprotein trimer bound to a prefusion-specific neutralizing antibody
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    Vps33B controls Treg cell suppressive function through inhibiting lysosomal nutrient sensing complex-mediated mTORC1 activation
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    Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging
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    Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer
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  66. Nov 2021
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    Global mitochondrial protein import proteomics reveal distinct regulation by translation and translocation machinery
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  68. Oct 2021
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    Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy
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    Quantitative proteomics reveals the selectivity of ubiquitin-binding autophagy receptors in the turnover of damaged lysosomes by lysophagy
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    Forelimb Motor Skills Deficits Following Thoracic Spinal Cord Injury: Underlying Dopaminergic and Neural Oscillatory Changes in Rat Primary Motor Cortex - Omid Salimi, Hamid Soltani Zangbar, Soheila Hajizadeh Shadiabad, Meysam Ghorbani, Tahereh Ghadiri, Abbas Ebrahimi Kalan, Hasan Kheyrkhah, Parviz Shahabi, 2021
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  73. Aug 2021
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  76. Jul 2021
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    GX15–070 (Obatoclax), a Bcl-2 family proteins inhibitor engenders apoptosis and pro-survival autophagy and increases Chemosensitivity in neuroblastoma
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    The TGFB2-AS1 lncRNA Regulates TGF-β Signaling by Modulating Corepressor Activity
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    Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas
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  82. Jun 2021
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    Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal
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  86. Apr 2021
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    Mechanism-Based Personalized Medicine for Cystic Fibrosis by Suppressing Pseudo Exon Inclusion
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    Cateslytin abrogates lipopolysaccharide-induced cardiomyocyte injury by reducing inflammation and oxidative stress through toll like receptor 4 interaction
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    Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma
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  91. Jan 2021
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    Facilitation of GluN2C-containing NMDA receptors in the external globus pallidus increases firing of fast spiking neurons and improves motor function in a hemiparkinsonian mouse model
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  96. Sep 2020
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    N-acetyl-L-cysteine reduces Leishmania amazonensis-induced inflammation in BALB/c mice
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    Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations
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    Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling
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    OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
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  103. Jan 2020
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    Functional Translatome Proteomics Reveal Converging and Dose-Dependent Regulation by mTORC1 and eIF2α
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    Calcium sensing receptor activation in THP-1 macrophages triggers NLRP3 inflammasome and human preadipose cell inflammation
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    Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate
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    Zfp281 Shapes the Transcriptome of Trophoblast Stem Cells and Is Essential for Placental Development
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    Histone H3K9 Methyltransferase G9a in Oocytes Is Essential for Preimplantation Development but Dispensable for CG Methylation Protection
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  113. Nov 2018
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    Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II
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    The lentiviral-mediated Nurr1 genetic engineering mesenchymal stem cells protect dopaminergic neurons in a rat model of Parkinson’s disease
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    Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics
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    The Amaryllidaceae Alkaloid Haemanthamine Binds the Eukaryotic Ribosome to Repress Cancer Cell Growth
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    Alteration of sphingolipid metabolism as a putative mechanism underlying LPS‐induced BBB disruption
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  120. Nov 2017
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    Novel Mutation of the RUNX2 Gene in Patients with Cleidocranial Dysplasia
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    Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication
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    Wnt5a inhibits K+ currents in hippocampal synapses through nitric oxide production
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