29 Matching Annotations
  1. Last 7 days
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    Identifying compound-protein interactions with knowledge graph embedding of perturbation transcriptomics
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    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.xgen.2024.100655

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    sciencedirect.com/science/article/pii/S2666979X24002660
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    Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell
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      DOI: 10.1016/j.xcrm.2024.101718

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    sciencedirect.com/science/article/pii/S2666379124004397
  4. Aug 2024
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells
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    1. scibot 23 Aug 2024
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      DOI: 10.7554/eLife.76940

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    ncbi.nlm.nih.gov/pmc/articles/PMC11333044/
  6. May 2024
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    A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation
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    1. scibot 31 May 2024
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      DOI: 10.1016/j.celrep.2024.114259

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    sciencedirect.com/science/article/pii/S2211124724005874
  8. Feb 2024
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    Systemic inflammatory response syndrome triggered by blood-borne pathogens induces prolonged dendritic cell paralysis and immunosuppression
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    1. scibot 14 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113754

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    sciencedirect.com/science/article/pii/S2211124724000822
  10. Jul 2023
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    A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity
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    1. scibot 13 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112813

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    sciencedirect.com/science/article/pii/S2211124723008240
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    Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity
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    1. scibot 07 Jul 2023
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      DOI: 10.1016/j.cell.2023.06.002

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    sciencedirect.com/science/article/pii/S0092867423006426
  13. Jun 2023
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    Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses
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    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.immuni.2023.05.011

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    sciencedirect.com/science/article/pii/S1074761323002285
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    Canonical BAF complex activity shapes the enhancer landscape that licenses CD8+ T cell effector and memory fates
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    1. scibot 23 Jun 2023
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      DOI: 10.1016/j.immuni.2023.05.005

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    sciencedirect.com/science/article/pii/S1074761323002224
  16. May 2023
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    Asymmetric cell division safeguards memory CD8 T cell development
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    1. scibot 13 May 2023
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      DOI: 10.1016/j.celrep.2023.112468

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    sciencedirect.com/science/article/pii/S2211124723004795
  18. Feb 2023
  19. www.embopress.org www.embopress.org
    Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer
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    1. scibot 23 Feb 2023
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      DOI: 10.15252/embr.202256524

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    embopress.org/doi/10.15252/embr.202256524
  20. Oct 2022
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance
    1
    1. scibot 26 Oct 2022
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      DOI: 10.1016/j.isci.2022.105233

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    ncbi.nlm.nih.gov/pmc/articles/PMC9579486/
  22. Apr 2022
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    Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches
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    1. scibot 07 Apr 2022
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      DOI: 10.1016/j.immuni.2022.03.006

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    sciencedirect.com/science/article/pii/S1074761322001297
  24. Nov 2021
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    Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade
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    1. scibot 24 Nov 2021
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      DOI: 10.1016/j.celrep.2021.110021

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    sciencedirect.com/science/article/pii/S2211124721015035
  26. Sep 2021
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    Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction
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    1. scibot 28 Sep 2021
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      DOI: 10.1016/j.immuni.2021.09.001

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    sciencedirect.com/science/article/pii/S1074761321003642
  28. Aug 2021
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    The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer
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    1. scibot 15 Aug 2021
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      DOI: 10.1016/j.ccell.2021.07.007

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    sciencedirect.com/science/article/pii/S1535610821003846
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    Disruption of Coronin 1 Signaling in T Cells Promotes Allograft Tolerance while Maintaining Anti-Pathogen Immunity
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    1. scibot 10 Aug 2021
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      DOI: 10.1016/j.immuni.2018.12.011

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    sciencedirect.com/science/article/pii/S1074761318305594
  31. May 2021
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T cell self-reactivity during thymic development dictates the timing of positive selection
    1
    1. scibot 19 May 2021
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      DOI: 10.7554/eLife.65435

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    ncbi.nlm.nih.gov/pmc/articles/PMC8116051/
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    Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8+ T cells during the primary immune response
    1
    1. scibot 07 May 2021
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      DOI: 10.1016/j.immuni.2021.02.018

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    sciencedirect.com/science/article/pii/S1074761321000844
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    Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment
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    1. scibot 06 May 2021
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      DOI: 10.1016/j.immuni.2020.08.005

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    sciencedirect.com/science/article/pii/S1074761320303587
  35. Apr 2021
  36. www.sciencedirect.com www.sciencedirect.com
    The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes
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      DOI: 10.1016/j.ccell.2020.09.001

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    sciencedirect.com/science/article/pii/S1535610820304323
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    Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
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    sciencedirect.com/science/article/pii/S1074761321001199
  38. Mar 2021
  39. www.sciencedirect.com www.sciencedirect.com
    Itaconate confers tolerance to late NLRP3 inflammasome activation
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    1. scibot 10 Mar 2021
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      DOI: 10.1016/j.celrep.2021.108756

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    sciencedirect.com/science/article/pii/S2211124721000693
  40. Dec 2020
  41. www.sciencedirect.com www.sciencedirect.com
    Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity
    1
    1. scibot 07 Dec 2020
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      DOI: 10.1016/j.cmet.2020.11.003

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    sciencedirect.com/science/article/pii/S1550413120305982
  42. Oct 2020
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Critical role of WNK1 in MYC-dependent early mouse thymocyte development
    1
    1. scibot 31 Oct 2020
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      DOI: 10.7554/eLife.56934

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    ncbi.nlm.nih.gov/pmc/articles/PMC7591260/
  44. www.cell.com www.cell.com
    Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response
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    1. scibot 18 Oct 2020
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      DOI: 10.1016/j.chom.2020.07.001

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    cell.com/cell-host-microbe/abstract/S1931-3128(20)30397-8
  45. Sep 2020
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation
    1
    1. scibot 17 Sep 2020
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      DOI: 10.7554/eLife.53725

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    ncbi.nlm.nih.gov/pmc/articles/PMC7056270/
  47. www.sciencedirect.com www.sciencedirect.com
    Lymphocyte-Specific Function of the DNA Polymerase Epsilon Subunit Pole3 Revealed by Neomorphic Alleles
    1
    1. scibot 03 Sep 2020
      100738

      DOI: 10.1016/j.celrep.2020.107756

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      Curator: @ethanbadger

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      Curator comments: CD8a BV421 Clone 53-6.7

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    sciencedirect.com/science/article/pii/S2211124720307361
  48. Jan 2020
  49. www.sciencedirect.com www.sciencedirect.com
    Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.celrep.2019.11.061

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    sciencedirect.com/science/article/pii/S2211124719315529