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A stroma-sensing TGF-β blockade reprograms CAF-myeloid niches to induce durable tumor immunity

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sciencedirect.com/science/article/pii/S1535610826004733
Nov 2026
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T cell cross-priming by PD-L1+ type 1 conventional dendritic cells mediates the antitumor efficacy of a PD-L1×4-1BB bispecific antibody

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Jul 2026
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Myeloid MMP14 couples extracellular proteolysis to inflammatory and metabolic remodeling during obesity

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1. scibot 11 Jul 2026
  
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  DOI: 10.1016/j.celrep.2026.117681
  
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sciencedirect.com/science/article/pii/S221112472600759X
Jun 2026
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Type I IFN-controlled Qa-2 expression identifies and maps the generation of Eomes+ thymic innate CD8 T cells

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1. scibot 29 Jun 2026
  
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Expansion and mobilization of virus-specific stem-like CD8 T cells in chronic viral infection after treatment with a long-acting IL-7, NT-I7

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1. scibot 03 Jun 2026
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13222646/
Apr 2026
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Inflammaging in aged tissues drives remodeling of the CD8+ T cell compartment

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  DOI: 10.1016/j.celrep.2026.117303
  
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1-s2.0-S2589004226011764-main-html.html

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54.241.53.176/8488015b440db33861248d6c24369f9587bf2f0a/1-s2.0-S2589004226011764-main-html.html
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Sulfur partitioning from cysteine controls T cell proliferation and effector function

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1. scibot 02 Apr 2026
  
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  DOI: 10.1016/j.cell.2026.03.012
  
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sciencedirect.com/science/article/pii/S0092867426002795
Dec 2025
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Positioning and reversible suppression of CCR7+ dendritic cells in perivascular tumor niches shape cancer immunity

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  DOI: 10.1016/j.immuni.2025.11.020
  
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sciencedirect.com:5037/science/article/pii/S1074761325005229
Nov 2025
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Vitamin B6 preserves the stemness-like phenotypes and antitumor ability of CD8+ T cells

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.devcel.2025.10.017
  
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sciencedirect.com:5037/science/article/pii/S1534580725006914
Aug 2025
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Bifidobacterium animalis suppresses non-small cell lung cancer progression and modulates tumor immunity through indole-3-acetic acid

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1. scibot 13 Aug 2025
  
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  DOI: 10.1016/j.celrep.2025.116132
  
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sciencedirect.com/science/article/pii/S2211124725009039
Jun 2025
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An organoid co-culture model for probing systemic anti-tumor immunity in lung cancer

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1. scibot 13 Jun 2025
  
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  DOI: 10.1016/j.stem.2025.05.011
  
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sciencedirect.com/science/article/pii/S1934590925001912
May 2025
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PIM kinase control of CD8 T cell protein synthesis and cell trafficking

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1. scibot 22 May 2025
  
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  DOI: 10.7554/eLife.98622
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12074636/
Apr 2025
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Immunological analysis of LC16m8 vaccine: preclinical and early clinical insights into mpox

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sciencedirect.com/science/article/pii/S2352396425001471
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Albumin-targeted oxaliplatin(iv) prodrugs bearing STING agonists

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1. scibot 08 Apr 2025
  
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  DOI: 10.1039/d5qi00433k
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11969438/
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Albumin-targeted oxaliplatin( iv ) prodrugs bearing STING agonists

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  DOI: 10.1039/D5QI00433K
  
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pubs.rsc.org/en/content/articlehtml/2025/qi/d5qi00433k
Jan 2025
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Targeted localization of the mother centrosome in CD8+ T cells undergoing asymmetric cell division promotes memory formation

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1. scibot 07 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115127
  
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sciencedirect.com/science/article/pii/S2211124724014785
Nov 2024
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Effects of gut microbiota on immune checkpoint inhibitors in multi-cancer and as microbial biomarkers for predicting therapeutic response

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1. scibot 17 Nov 2024
  
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  DOI: 10.1016/j.medj.2024.10.007
  
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sciencedirect.com/science/article/pii/S2666634024004057
Sep 2024
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Identifying compound-protein interactions with knowledge graph embedding of perturbation transcriptomics

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  DOI: 10.1016/j.xgen.2024.100655
  
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Dietary vitamin B3 supplementation induces the antitumor immunity against liver cancer via biased GPR109A signaling in myeloid cell

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  DOI: 10.1016/j.xcrm.2024.101718
  
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Aug 2024
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Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells

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  DOI: 10.7554/eLife.76940
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11333044/
May 2024
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A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation

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1. scibot 31 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114259
  
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Feb 2024
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Systemic inflammatory response syndrome triggered by blood-borne pathogens induces prolonged dendritic cell paralysis and immunosuppression

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  DOI: 10.1016/j.celrep.2024.113754
  
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Jul 2023
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A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity

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1. scibot 13 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112813
  
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Vaccine-boosted CAR T crosstalk with host immunity to reject tumors with antigen heterogeneity

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  DOI: 10.1016/j.cell.2023.06.002
  
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Jun 2023
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Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses

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1. scibot 23 Jun 2023
  
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  DOI: 10.1016/j.immuni.2023.05.011
  
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Canonical BAF complex activity shapes the enhancer landscape that licenses CD8+ T cell effector and memory fates

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1. scibot 23 Jun 2023
  
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  DOI: 10.1016/j.immuni.2023.05.005
  
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sciencedirect.com/science/article/pii/S1074761323002224
May 2023
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Asymmetric cell division safeguards memory CD8 T cell development

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  DOI: 10.1016/j.celrep.2023.112468
  
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Feb 2023
www.embopress.org www.embopress.org

Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer

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  DOI: 10.15252/embr.202256524
  
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embopress.org/doi/10.15252/embr.202256524
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance

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1. scibot 26 Oct 2022
  
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  DOI: 10.1016/j.isci.2022.105233
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9579486/
Apr 2022
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Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches

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1. scibot 07 Apr 2022
  
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  DOI: 10.1016/j.immuni.2022.03.006
  
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sciencedirect.com/science/article/pii/S1074761322001297
Nov 2021
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Reprogramming NK cells and macrophages via combined antibody and cytokine therapy primes tumors for elimination by checkpoint blockade

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1. scibot 24 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.110021
  
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sciencedirect.com/science/article/pii/S2211124721015035
Sep 2021
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Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction

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1. scibot 28 Sep 2021
  
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  DOI: 10.1016/j.immuni.2021.09.001
  
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sciencedirect.com/science/article/pii/S1074761321003642
Aug 2021
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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

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1. scibot 15 Aug 2021
  
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  DOI: 10.1016/j.ccell.2021.07.007
  
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sciencedirect.com/science/article/pii/S1535610821003846
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Disruption of Coronin 1 Signaling in T Cells Promotes Allograft Tolerance while Maintaining Anti-Pathogen Immunity

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1. scibot 10 Aug 2021
  
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  DOI: 10.1016/j.immuni.2018.12.011
  
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sciencedirect.com/science/article/pii/S1074761318305594
May 2021
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T cell self-reactivity during thymic development dictates the timing of positive selection

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1. scibot 19 May 2021
  
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  DOI: 10.7554/eLife.65435
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8116051/
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Single-cell analysis by mass cytometry reveals metabolic states of early-activated CD8+ T cells during the primary immune response

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1. scibot 07 May 2021
  
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  DOI: 10.1016/j.immuni.2021.02.018
  
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pmc.ncbi.nlm.nih.gov/articles/PMC8046726/
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Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment

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1. scibot 06 May 2021
  
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  DOI: 10.1016/j.immuni.2020.08.005
  
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sciencedirect.com/science/article/pii/S1074761320303587
Apr 2021
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The PD-1/PD-L1-Checkpoint Restrains T cell Immunity in Tumor-Draining Lymph Nodes

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1. scibot 22 Apr 2021
  
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  DOI: 10.1016/j.ccell.2020.09.001
  
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sciencedirect.com/science/article/pii/S1535610820304323
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Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells

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1. scibot 01 Apr 2021
  
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  DOI: 10.1016/j.immuni.2021.03.007
  
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sciencedirect.com/science/article/pii/S1074761321001199
Mar 2021
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Itaconate confers tolerance to late NLRP3 inflammasome activation

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1. scibot 10 Mar 2021
  
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  DOI: 10.1016/j.celrep.2021.108756
  
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sciencedirect.com/science/article/pii/S2211124721000693
Dec 2020
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Dynamic Cardiolipin Synthesis Is Required for CD8+ T Cell Immunity

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1. scibot 07 Dec 2020
  
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  DOI: 10.1016/j.cmet.2020.11.003
  
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sciencedirect.com/science/article/pii/S1550413120305982
Oct 2020
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Critical role of WNK1 in MYC-dependent early mouse thymocyte development

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1. scibot 31 Oct 2020
  
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  DOI: 10.7554/eLife.56934
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7591260/
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Antibody Feedback Limits the Expansion of B Cell Responses to Malaria Vaccination but Drives Diversification of the Humoral Response

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1. scibot 18 Oct 2020
  
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  DOI: 10.1016/j.chom.2020.07.001
  
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cell.com/cell-host-microbe/abstract/S1931-3128(20)30397-8
Sep 2020
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Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation

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1. scibot 17 Sep 2020
  
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  DOI: 10.7554/eLife.53725
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7056270/
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Lymphocyte-Specific Function of the DNA Polymerase Epsilon Subunit Pole3 Revealed by Neomorphic Alleles

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1. scibot 03 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107756
  
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  Curator comments: CD8a BV421 Clone 53-6.7
  
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sciencedirect.com/science/article/pii/S2211124720307361
Jan 2020
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Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.celrep.2019.11.061
  
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sciencedirect.com/science/article/pii/S2211124719315529