36 Matching Annotations
  1. Sep 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of resistance mechanisms to small-molecule inhibition of TEAD-regulated transcription
    1
    1. scibot 26 Sep 2024
      RRID:AB_11217435

      DOI: 10.1038/s44319-024-00217-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11387499/
  3. www.sciencedirect.com www.sciencedirect.com
    Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma
    1
    1. scibot 12 Sep 2024
      RRID:AB_11217435

      DOI: 10.1016/j.celrep.2024.114721

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    sciencedirect.com/science/article/pii/S2211124724010726
  4. www.sciencedirect.com www.sciencedirect.com
    A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
    1
    1. scibot 04 Sep 2024
      AB_11217435

      DOI: 10.1016/j.xcrm.2024.101703

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    sciencedirect.com/science/article/pii/S2666379124004245
  5. Aug 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Feedforward cysteine regulation maintains melanoma differentiation state and limits metastatic spread
    1
    1. scibot 21 Aug 2024
      AB_11217435

      DOI: 10.1016/j.celrep.2024.114484

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    ncbi.nlm.nih.gov/pmc/articles/PMC11316253/
  7. May 2024
  8. 52.53.155.43 52.53.155.43
    Phenotype-specific melanoma uptake of fatty acid from human adipocytes activates AXL and CAV1-dependent β-catenin nuclear accumulation
    1
    1. scibot 04 May 2024
      AB_11217435

      DOI: 10.1101/2024.01.21.576568

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    52.53.155.43/5631ba0ece03be5b6bc39fba9c8a58e52d07c519/2024.01.21.576568v1.full-html.html
  9. Apr 2024
  10. aacrjournals.org aacrjournals.org
    AXL/WRNIP1 mediates replication stress response and promotes therapy resistance and metachronous metastasis in HER2+ breast cancer
    1
    1. scibot 19 Apr 2024
      RRID:AB_11217435

      DOI: 10.1158/0008-5472.CAN-23-1459

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    aacrjournals.org/cancerres/article/84/5/675/734930/AXL-WRNIP1-Mediates-Replication-Stress-Response
  11. Aug 2023
  12. 52.53.155.43 52.53.155.43
    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
    2
    1. scibot 18 Aug 2023
      RRID:AB_11217435

      DOI: 10.1016/j.xcrm.2023.101142

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    2. scibot 10 Aug 2023
      RRID:AB_11217435

      DOI: 10.1016/j.xcrm.2023.101142

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    52.53.155.43/bb31ad2b14838f5cede2aca897c595e2febf2f88/PIIS2666379123002951-html.html
  13. www.sciencedirect.com www.sciencedirect.com
    Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer
    1
    1. scibot 04 Aug 2023
      RRID:AB_11217435

      DOI: 10.1016/j.ccell.2023.07.005

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    sciencedirect.com/science/article/pii/S1535610823002453
  14. Jun 2023
  15. dx.doi.org dx.doi.org
    LZTR1 mutation mediates oncogenesis through stabilization of EGFR and AXL
    1
    1. scibot 08 Jun 2023
      RRID:AB_11217435

      DOI: 10.1158/2159-8290.CD-22-0376

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    dx.doi.org/10.1158/2159-8290.CD-22-0376
  16. Feb 2023
  17. 52.53.155.43 52.53.155.43
    cd-22-0376-html.html
    1
    1. scibot 17 Feb 2023
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      DOI: 10.1158/2159-8290.CD-22-0376

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    52.53.155.43/a051cdc9b66cfe47aeb3f39770c1ce7cd380afb2/cd-22-0376-html.html
  18. www.sciencedirect.com www.sciencedirect.com
    CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance
    1
    1. scibot 16 Feb 2023
      RRID:AB_11217435

      DOI: 10.1016/j.ccell.2023.01.007

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    sciencedirect.com/science/article/pii/S1535610823000077
  19. www.sciencedirect.com www.sciencedirect.com
    Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
    1
    1. scibot 03 Feb 2023
      RRID:AB_11217435

      DOI: 10.1016/j.molcel.2023.01.015

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    sciencedirect.com/science/article/pii/S1097276523000382
  20. www.sciencedirect.com www.sciencedirect.com
    Direct activation of microglia by β-glucosylceramide causes phagocytosis of neurons that exacerbates Gaucher disease
    1
    1. scibot 03 Feb 2023
      RRID:AB_11217435

      DOI: 10.1016/j.immuni.2023.01.008

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    sciencedirect.com/science/article/pii/S1074761323000183
  21. Jan 2023
  22. aacrjournals.org aacrjournals.org
    ER-001259851-000, a novel selective inhibitor of AXL, overcomes resistance to antimitotic drugs
    1
    1. scibot 14 Jan 2023
      RRID:AB_11217435

      DOI: 10.1158/1535-7163.MCT-21-0879

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    aacrjournals.org/mct/article/22/1/12/711996/ER-851-a-Novel-Selective-Inhibitor-of-AXL
  23. Aug 2022
  24. www.sciencedirect.com www.sciencedirect.com
    ABL kinases regulate translation in HER2+ cells through Y-box-binding protein 1 to facilitate colonization of the brain
    1
    1. scibot 31 Aug 2022
      RRID:AB_11217435

      DOI: 10.1016/j.celrep.2022.111268

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    sciencedirect.com/science/article/pii/S2211124722010865
  25. Jul 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity
    1
    1. scibot 13 Jul 2022
      RRID:AB_11217435

      DOI: 10.1016/j.ccell.2022.06.006

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    sciencedirect.com/science/article/pii/S1535610822002707
  27. Mar 2022
  28. www.sciencedirect.com www.sciencedirect.com
    AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells
    1
    1. scibot 18 Mar 2022
      RRID:AB_11217435

      DOI: 10.1016/j.xcrm.2022.100554

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    sciencedirect.com/science/article/pii/S266637912200060X
  29. Feb 2022
  30. www.sciencedirect.com www.sciencedirect.com
    A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
    1
    1. scibot 23 Feb 2022
      RRID:AB_11217435

      DOI: 10.1016/j.molcel.2022.01.022

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    sciencedirect.com/science/article/pii/S1097276522000879
  31. Jan 2022
  32. onlinelibrary.wiley.com onlinelibrary.wiley.com
    SKI-G-801, an AXL kinase inhibitor, blocks metastasis through inducing anti-tumor immune responses and potentiates anti-PD-1 therapy in mouse cancer models
    1
    1. scibot 05 Jan 2022
      8661

      DOI: 10.1002/cti2.1364

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    onlinelibrary.wiley.com/doi/10.1002/cti2.1364
  33. Dec 2021
  34. elifesciences.org elifesciences.org
    BRAFV600E induces reversible mitotic arrest in human melanocytes via microrna-mediated suppression of AURKB
    1
    1. scibot 01 Dec 2021
      RRID:AB_11217435

      DOI: 10.7554/eLife.70385

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    elifesciences.org/articles/70385
  35. Nov 2021
  36. www.sciencedirect.com www.sciencedirect.com
    FARP1, ARHGEF39, and TIAM2 are essential receptor tyrosine kinase effectors for Rac1-dependent cell motility in human lung adenocarcinoma
    1
    1. scibot 03 Nov 2021
      RRID:AB_11217435

      DOI: 10.1016/j.celrep.2021.109905

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    sciencedirect.com/science/article/pii/S2211124721013759
  37. Aug 2021
  38. www.sciencedirect.com www.sciencedirect.com
    The FAPα-activated prodrug Z-GP-DAVLBH inhibits the growth and pulmonary metastasis of osteosarcoma cells by suppressing the AXL pathway
    1
    1. scibot 17 Aug 2021
      8661

      DOI: 10.1016/j.apsb.2021.08.015

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    sciencedirect.com/science/article/pii/S2211383521003051
  39. Jul 2021
  40. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The effect of Zika virus infection in the ferret
    1
    1. scibot 31 Jul 2021
      RRID:AB_11217435

      DOI: 10.1002/cne.24640

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    onlinelibrary.wiley.com/doi/full/10.1002/cne.24640
  41. Apr 2021
  42. www.sciencedirect.com www.sciencedirect.com
    Pharmacoproteomics Identifies Kinase Pathways that Drive the Epithelial-Mesenchymal Transition and Drug Resistance in Hepatocellular Carcinoma
    1
    1. scibot 27 Apr 2021
      RRID:AB_11217435

      DOI: 10.1016/j.cels.2020.07.006

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    sciencedirect.com/science/article/pii/S2405471220302490
  43. Oct 2020
  44. www.sciencedirect.com www.sciencedirect.com
    Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells
    1
    1. scibot 31 Oct 2020
      RRID:AB_11217435

      DOI: 10.1016/j.cels.2020.10.002

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    sciencedirect.com/science/article/pii/S2405471220303707
  45. Sep 2020
  46. www.sciencedirect.com www.sciencedirect.com
    Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis
    1
    1. scibot 17 Sep 2020
      RRID:AB_11217435

      DOI: 10.1016/j.stem.2020.04.001

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    sciencedirect.com/science/article/pii/S1934590920301405
  47. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
    1
    1. scibot 07 Sep 2020
      RRID:AB_11217435

      DOI: 10.1016/j.ccell.2019.12.007

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    sciencedirect.com/science/article/pii/S153561081930577X
  48. Jan 2020
  49. www.sciencedirect.com www.sciencedirect.com
    Lineage-Restricted Regulation of SCD and Fatty Acid Saturation by MITF Controls Melanoma Phenotypic Plasticity
    1
    1. scibot 13 Jan 2020
      RRID:AB_11217435

      DOI: 10.1016/j.molcel.2019.10.014

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    sciencedirect.com/science/article/pii/S1097276519307920
  50. www.sciencedirect.com www.sciencedirect.com
    A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis
    1
    1. scibot 13 Jan 2020
      RRID:AB_11217435

      DOI: 10.1016/j.celrep.2019.11.018

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    sciencedirect.com/science/article/pii/S2211124719314895
  51. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The effect of Zika virus infection in the ferret
    1
    1. scibot 13 Jan 2020
      RRID:AB_11217435

      DOI: 10.1002/cne.24640

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    onlinelibrary.wiley.com/doi/full/10.1002/cne.24640
  52. www.sciencedirect.com www.sciencedirect.com
    OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ
    1
    1. scibot 12 Jan 2020
      RRID:AB_11217435

      DOI: 10.1016/j.molcel.2018.10.030

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    sciencedirect.com/science/article/pii/S1097276518308906
  53. Nov 2018
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 05 Nov 2018
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    ncbi.nlm.nih.gov/pmc/articles/PMC6075866/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
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    1. scibot 05 Nov 2018
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    ncbi.nlm.nih.gov/pmc/articles/PMC5926201/
  56. www.sciencedirect.com www.sciencedirect.com
    Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1535610818301223
  57. Nov 2017
  58. www.sciencedirect.com www.sciencedirect.com
    Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids
    1
    1. scibot 08 Nov 2017
      AB_11217435

      Curator: @Zeljana_Babic

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    sciencedirect.com/science/article/pii/S1934590916304611