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54.241.53.176 54.241.53.176

1-s2.0-S2589004226002919-main-html.html

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1. scibot 12 Feb 2026
  
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  DOI: 10.1016/j.isci.2026.114916
  
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54.241.53.176/de87b604a1091caaf3c564749c338172c68f3aa2/1-s2.0-S2589004226002919-main-html.html
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ESM1 SUMOylation mediates bevacizumab resistance in ovarian cancer through ITGB1-FAK-driven angiogenesis

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1. scibot 06 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.116927
  
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sciencedirect.com/science/article/pii/S2211124726000057
Feb 2026
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Delactylation of the tumor suppressor ARHGDIB drives metastasis and chemoresistance in bladder cancer

1
1. scibot 05 Feb 2026
  
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  DOI: 10.1016/j.celrep.2026.116941
  
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sciencedirect.com/science/article/pii/S2211124726000197
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Targeting the LHX1-LDB1 Complex Restores STING-dependent Senescence Surveillance and Inhibits Head and Neck Cancer Progression

1
1. scibot 30 Jan 2026
  
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  DOI: 10.7150/ijbs.123790
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12836506/
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NuMA promotes constitutive heterochromatin compaction by stabilizing linker histone H1 on chromatin

1
1. scibot 27 Jan 2026
  
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  DOI: 10.1016/j.celrep.2025.116901
  
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sciencedirect.com/science/article/pii/S2211124725016730
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The UFL1-AKT positive feedback loop promotes breast cancer progression by enhancing lipid synthesis

1
1. scibot 23 Jan 2026
  
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  DOI: 10.1038/s41467-026-68492-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12820292/
54.241.53.176 54.241.53.176

paper2-html.html

1
1. scibot 22 Jan 2026
  
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  AB_11232216
  
  DOI: 10.1002/advs.202509846
  
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54.241.53.176/7004e19049be5918255dd11820146e335ff22431/paper2-html.html
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Migrasome-driven mitocytosis relieves mitochondrial damage induced by chikungunya virus TF and 6K

1
1. scibot 13 Jan 2026
  
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  DOI: 10.1016/j.hlife.2025.12.002
  
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sciencedirect.com/science/article/pii/S2949928325001178
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UBE2O-mediated monoubiquitination licenses NLRP6 inflammasome activation in the intestine

1
1. scibot 09 Jan 2026
  
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  RRID:AB_11232216
  
  DOI: 10.1016/j.chom.2025.12.009
  
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sciencedirect.com/science/article/pii/S1931312825005281
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Cell-surface RNA forms ternary complex with RNA-binding proteins and heparan sulfate to recruit immune receptors

1
1. scibot 20 Dec 2025
  
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  DOI: 10.1016/j.molcel.2025.11.020
  
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sciencedirect.com:5037/science/article/pii/S1097276525009372
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Annexin A7 enhances TIA1 axonal trafficking to counteract pathological aggregation in neurons

1
1. scibot 18 Dec 2025
  
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  DOI: 10.1038/s44318-025-00609-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12706091/
54.241.53.176 54.241.53.176

s12974-025-03648-4_reference-html.html

1
1. scibot 16 Dec 2025
  
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  AB_11232216
  
  DOI: 10.1186/s12974-025-03648-4
  
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54.241.53.176/a44cc0e7569e6d3c1fa351bb4696d083040f2f89/s12974-025-03648-4_reference-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

NAT10 promotes cancer metastasis by modulating p300/CBP activity through chromatin-associated tRNA

1
1. scibot 04 Dec 2025
  
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  RRID:AB_11232216
  
  DOI: 10.1016/j.molcel.2025.11.010
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12709618/
Nov 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Lysine methylation-mediated SMYD2 degradation by casticin sensitizes non-small-cell lung cancer cells to osimertinib therapy

1
1. scibot 29 Nov 2025
  
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  AB_11232216
  
  DOI: 10.1016/j.bcp.2025.117562
  
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sciencedirect.com:5037/science/article/pii/S0006295225008275
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mutant NPM1 modulates PDCD4 ubiquitination degradation and facilitates leukemogenesis

1
1. scibot 20 Nov 2025
  
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  RRID:AB_11232216
  
  DOI: 10.1016/j.isci.2025.113776
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12604968/
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Diet-metabolism-transcription axis modulates the sensitivity to CDK4/6 inhibitors through RB1 in prostate cancer

1
1. scibot 06 Nov 2025
  
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  RRID:AB_11232216
  
  DOI: 10.1016/j.celrep.2025.116530
  
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sciencedirect.com/science/article/pii/S2211124725013014
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WDFY2 promotes MRN complex formation required for homologous recombination-mediated DNA repair

1
1. scibot 05 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116520
  
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sciencedirect.com/science/article/pii/S2211124725012914
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PCAF-mediated acetylation regulates RAD51 dynamic localization on chromatin during HR repair | EMBO reports

1
1. scibot 29 Oct 2025
  
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  RRID:AB_11232216
  
  DOI: 10.1038/s44319-025-00513-6
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12373954/
www.embopress.org www.embopress.org

PCAF-mediated acetylation regulates RAD51 dynamic localization on chromatin during HR repair

1
1. scibot 29 Oct 2025
  
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  DOI: 10.1038/s44319-025-00513-6
  
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embopress.org/doi/10.1038/s44319-025-00513-6
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STBD1 mediates the crosstalk between glycogen and lipid droplets in clear cell renal cell carcinoma

1
1. scibot 18 Oct 2025
  
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  DOI: 10.1016/j.celrep.2025.116429
  
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54.241.53.176 54.241.53.176

1-s2.0-S2589004225020371-main-html.html

1
1. scibot 16 Oct 2025
  
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  RRID:AB_11232216
  
  DOI: 10.1016/j.isci.2025.113776
  
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54.241.53.176/29f04397bccbdb8243f5905e7e183223848ea6e3/1-s2.0-S2589004225020371-main-html.html
Sep 2025
www.sciencedirect.com www.sciencedirect.com

HEBP2-governed glutamine competition between tumor and macrophages dictates immunotherapy efficacy in triple-negative breast cancer

1
1. scibot 24 Sep 2025
  
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  DOI: 10.1016/j.cmet.2025.08.009
  
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sciencedirect.com/science/article/pii/S1550413125003821
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RSK1 reprograms the ubiquitin pathway to promote immune suppression

1
1. scibot 23 Sep 2025
  
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  RRID:AB_11232216
  
  DOI: 10.1016/j.celrep.2025.116323
  
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sciencedirect.com/science/article/pii/S2211124725010940
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A pathological role of O-GlcNAcylation-driven TR11B production and function in lung adenocarcinoma

1
1. scibot 11 Sep 2025
  
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  DOI: 10.1016/j.devcel.2025.08.010
  
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sciencedirect.com/science/article/pii/S1534580725005301
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Targeting USP21 to inhibit abdominal aortic aneurysm progression by suppressing the phenotypic transition of vascular smooth muscle cells

1
1. scibot 09 Sep 2025
  
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  RRID:AB_11232216
  
  DOI: 10.1016/j.xcrm.2025.102328
  
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sciencedirect.com/science/article/pii/S266637912500401X
Jul 2025
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 30 Jul 2025
  
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  AB_11232216
  
  DOI: 10.1111/bph.70122
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.70122
www.nature.com www.nature.com

RFX2-BNIP3 axis-driven adaptive mitophagy promotes resistance to ACK1-targeted therapy in non-small cell lung cancer

1
1. scibot 29 Jul 2025
  
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  RRID:AB_11232216
  
  DOI: 10.1038/s41388-025-03502-0
  
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nature.com/articles/s41388-025-03502-0
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Phosphoglycerate kinase 1 contributes to diabetic kidney disease through enzyme-dependent and independent manners

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1. scibot 22 Jul 2025
  
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  DOI: 10.1016/j.xcrm.2025.102241
  
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sciencedirect.com/science/article/pii/S2666379125003143
52.53.155.43 52.53.155.43

1-s2.0-S2589004225014269-main-html.html

1
1. scibot 22 Jul 2025
  
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  RRID:AB_11232216
  
  DOI: 10.1016/j.isci.2025.113165
  
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52.53.155.43/6e3d057236c9c80ec002fca49c302ca5246dd6e8/1-s2.0-S2589004225014269-main-html.html
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TM9SF3 is a Golgi-resident ATG8-binding protein essential for Golgi-selective autophagy

1
1. scibot 02 Jul 2025
  
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  DOI: 10.1016/j.devcel.2025.06.017
  
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sciencedirect.com/science/article/pii/S1534580725003727
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Cardiomyocyte-derived YOD1 promotes pathological cardiac hypertrophy by deubiquitinating and stabilizing STAT3

1
1. scibot 02 Jul 2025
  
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  RRID:AB_11232216
  
  DOI: 10.1126/sciadv.adu8422
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12189954/
Jun 2025
www.science.org www.science.org

Cardiomyocyte-derived YOD1 promotes pathological cardiac hypertrophy by deubiquitinating and stabilizing STAT3

1
1. scibot 28 Jun 2025
  
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  RRID:AB_11232216
  
  DOI: 10.1126/sciadv.adu8422
  
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science.org/doi/10.1126/sciadv.adu8422
www.cell.com www.cell.com

BAG2 releases SAMD4B upon sensing of arginine deficiency to promote tumor cell survival

1
1. scibot 28 Jun 2025
  
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  RRID:AB_11232216
  
  DOI: 10.1016/j.molcel.2025.05.035
  
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cell.com/molecular-cell/fulltext/S1097-2765(25)00499-X
rupress.org rupress.org

Arc controls organ architecture through modulation of Crb and MyoII

1
1. scibot 17 Jun 2025
  
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  AB_11232216
  
  DOI: 10.1083/jcb.202409078
  
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rupress.org/jcb/article/224/9/e202409078/278051/Arc-controls-organ-architecture-through-modulation
elifesciences.org elifesciences.org

RUNX2 isoform II protects cancer cells from ferroptosis and apoptosis by promoting PRDX2 expression in oral squamous cell carcinoma

1
1. scibot 13 Jun 2025
  
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  DOI: 10.7554/eLife.99122
  
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Phosphatase activity is dispensable for PRL-3-mediated oncogenesis and tumor progression

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PGK1 phosphorylates NLRP3 and mediates inflammasome activation independent of its glycolytic activity

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Sertm2 is a conserved micropeptide that promotes GDNF-mediated motor neuron subtype specification

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Condensation-dependent multivalent interactions of EB1 and CENP-R regulate chromosome oscillations in mitosis

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ZBP1 senses splicing aberration through Z-RNA to promote cell death

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THBS2-producing matrix CAFs promote colorectal cancer progression and link to poor prognosis via the CD47-MAPK axis

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LAMP2A-mediated neuronal hyperexcitability by enhancing NKAβ1 degradation underlies depression-induced allodynia

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A neuronal Slit1-dependent program rescues oligodendrocyte differentiation and myelination under chronic hypoxic conditions

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Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma

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β-hydroxybutyrate facilitates mitochondrial-derived vesicle biogenesis and improves mitochondrial functions

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Tenascin-C Potentiates Wnt Signaling in Thyroid Cancer

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KRAS4B oncogenic mutants promote non-small cell lung cancer progression via the interaction of deubiquitinase USP25 with RNF31

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STAT3-controlled CHI3L1/SPP1 positive feedback loop demonstrates the spatial heterogeneity and immune characteristics of glioblastoma

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A methyltransferase-independent role for METTL1 in tRNA aminoacylation and oncogenic transformation

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N-terminal acetylation of transcription factor LIP induces immune therapy resistance via suppression of PD-L1 expression in non-small cell lung cancer

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SIRT3 differentially regulates lysine benzoylation from SIRT2 in mammalian cells

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HSV-1-induced N6-methyladenosine reprogramming via ICP0-mediated suppression of METTL14 potentiates oncolytic activity in glioma

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PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2

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Glycometabolic reprogramming-induced XRCC1 lactylation confers therapeutic resistance in ALDH1A3-overexpressing glioblastoma

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Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation

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Artemisinins ameliorate polycystic ovarian syndrome by mediating LONP1-CYP11A1 interaction

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Human promoter directionality is determined by transcriptional initiation and the opposing activities of INTS11 and CDK9

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Evolution of paralogous multicomponent systems for site-specific O-sialylation of flagellin in Gram-negative and Gram-positive bacteria

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A designed ankyrin-repeat protein that targets Parkinson’s disease-associated LRRK2

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Intestinal CXCR6+ ILC3s migrate to the kidney and exacerbate renal fibrosis via IL-23 receptor signaling enhanced by PD-1 expression

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Phosphorylation of Doc2 by EphB2 modulates Munc13-mediated SNARE complex assembly and neurotransmitter release

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CHES1 modulated tumorigenesis and senescence of pancreas cancer cells through repressing AKR1B10

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Ubiquitin ligase TRIM15 promotes the progression of pancreatic cancer via the upregulation of the IGF2BP2-TLR4 axis

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Mar 2024
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Engineered CBEs based on Macaca fascicularis A3A with improved properties for precise genome editing

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Feb 2024
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AURKA enhances the glycolysis and development of ovarian endometriosis through ERβ

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hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility

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Dual roles of CCDC102A in governing centrosome duplication and cohesion

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Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells

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Grass carp reovirus VP56 and VP35 induce formation of viral inclusion bodies for replication

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Glia-specific expression of neuropeptide receptor Lgr4 regulates development and adult physiology in Drosophila

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A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase

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E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC

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Transitional cell states sculpt tissue topology during lung regeneration

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MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression

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Phosphorylated YBX2 is stabilized to promote glycolysis in brown adipocytes

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Gcn5- and Bre1-mediated Set2 degradation promotes chronological aging of Saccharomyces cerevisiae

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ALKBH5-mediated m6A modification of HS3ST3B1-IT1 prevents osteoarthritis progression

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Multi-omics profiling reveals rhythmic liver function shaped by meal timing

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Deciphering the functional landscape of phosphosites with deep neural network

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Hypermethylation of RNF125 promotes autophagy-induced oxidative stress in asthma by increasing HMGB1 stability

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LINC00116-Encoded Microprotein Mitoregulin Regulates Fatty Acid Metabolism at the Mitochondrial Outer Membrane

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LncRNA DGCR5-encoded polypeptide RIP aggravates SONFH by repressing nuclear localization of β-catenin in BMSCs

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GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner

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An HBV susceptibility variant of KNG1 modulates the therapeutic effects of interferons α and λ1 in HBV infection by promoting MAVS lysosomal degradation

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Glycolytic enzyme HK2 promotes PD-L1 expression and breast cancer cell immune evasion

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Identification of XAF1 as an endogenous AKT inhibitor

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Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal

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A restrictor complex of ZC3H4, WDR82, and ARS2 integrates with PNUTS to control unproductive transcription

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Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity

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FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis

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MTHFD2 reprograms macrophage polarization by inhibiting PTEN

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Tyrosine phosphorylation tunes chemical and thermal sensitivity of TRPV2 ion channel

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FXR1 regulates vascular smooth muscle cell cytoskeleton, VSMC contractility, and blood pressure by multiple mechanisms

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The complement inhibitor CD59 is required for GABAergic synaptic transmission in the dentate gyrus

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Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting

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STING activation in platelets aggravates septic thrombosis by enhancing platelet activation and granule secretion

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BPS Publications

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EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in neurons

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Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle

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Structural insights into pathogenic mechanism of hypohidrotic ectodermal dysplasia caused by ectodysplasin A variants

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Jan 2023
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Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance

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THOC5 complexes with DDX5, DDX17, and CDK12 to regulate R loop structures and transcription elongation rate

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The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region

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Lysine crotonylation regulates leucine-deprivation-induced autophagy by a 14-3-3ε-PPM1B axis

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A Novel NF2 Splicing Mutant Causes Neurofibromatosis Type 2 via Liquid-liquid Phase Separation with LATS and Hippo Pathway.

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Mitochondrial microproteins link metabolic cues to respiratory chain biogenesis

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S-palmitoylation of PCSK9 induces sorafenib resistance in liver cancer by activating the PI3K/AKT pathway

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NRBF2 regulates the chemoresistance of small cell lung cancer by interacting with the P62 protein in the autophagy process

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Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells

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Native proline-rich motifs exploit sequence context to target actin-remodeling Ena/VASP protein ENAH

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PTEN alleviates maladaptive repair of renal tubular epithelial cells by restoring CHMP2A-mediated phagosome closure

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NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain

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Ca2+ sensor-mediated ROS scavenging suppresses rice immunity and is exploited by a fungal effector

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Interferon functional analog activates antiviral Jak/Stat signaling through integrin in an arthropod

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Pantoprazole ameliorates liver fibrosis and suppresses hepatic stellate cell activation in bile duct ligation rats by promoting YAP degradation

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Long noncoding RNA lnc-POP1-1 upregulated by VN1R5 promotes cisplatin resistance in head and neck squamous cell carcinoma through interaction with MCM5

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An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress

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Molecular basis for recognition of Gly/N-degrons by CRL2ZYG11B and CRL2ZER1

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SAS-6 Association with γ-Tubulin Ring Complex Is Required for Centriole Duplication in Human Cells

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Cytoplasmic polyadenylation by TENT5A is required for proper bone formation

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Nascent Pre-rRNA Sorting via Phase Separation Drives the Assembly of Dense Fibrillar Components in the Human Nucleolus

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Dynamic Imaging of RNA in Living Cells by CRISPR-Cas13 Systems

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CCDC84 Acetylation Oscillation Regulates Centrosome Duplication by Modulating HsSAS-6 Degradation

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Untitled document

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FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis

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