72 Matching Annotations
  1. Last 7 days
  2. www.science.org www.science.org
    Artemisinins ameliorate polycystic ovarian syndrome by mediating LONP1-CYP11A1 interaction
    1
    1. scibot 18 Jul 2024
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      DOI: 10.1126/science.adk5382

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  3. Jul 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human promoter directionality is determined by transcriptional initiation and the opposing activities of INTS11 and CDK9
    1
    1. scibot 12 Jul 2024
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      DOI: 10.7554/eLife.92764

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    ncbi.nlm.nih.gov/pmc/articles/PMC11230626/
  5. Jun 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Evolution of paralogous multicomponent systems for site-specific O-sialylation of flagellin in Gram-negative and Gram-positive bacteria
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    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.cub.2024.05.058

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    sciencedirect.com/science/article/pii/S0960982224007012
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    A designed ankyrin-repeat protein that targets Parkinson’s disease-associated LRRK2
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    1. scibot 21 Jun 2024
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    sciencedirect.com/science/article/pii/S0021925824019707
  8. May 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Intestinal CXCR6+ ILC3s migrate to the kidney and exacerbate renal fibrosis via IL-23 receptor signaling enhanced by PD-1 expression
    1
    1. scibot 30 May 2024
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      DOI: 10.1016/j.immuni.2024.05.004

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    sciencedirect.com/science/article/pii/S1074761324002553
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    Phosphorylation of Doc2 by EphB2 modulates Munc13-mediated SNARE complex assembly and neurotransmitter release
    1
    1. scibot 19 May 2024
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      DOI: 10.1126/sciadv.adi7024

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    ncbi.nlm.nih.gov/pmc/articles/PMC11100570/
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    CHES1 modulated tumorigenesis and senescence of pancreas cancer cells through repressing AKR1B10
    1
    1. scibot 09 May 2024
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    sciencedirect.com/science/article/pii/S0925443924002035
  12. Apr 2024
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    Ubiquitin ligase TRIM15 promotes the progression of pancreatic cancer via the upregulation of the IGF2BP2-TLR4 axis
    1
    1. scibot 23 Apr 2024
      20543–1-AP, Proteintech

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    sciencedirect.com/science/article/pii/S0925443924001728
  14. Mar 2024
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    Engineered CBEs based on Macaca fascicularis A3A with improved properties for precise genome editing
    1
    1. scibot 05 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113878

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    sciencedirect.com/science/article/pii/S2211124724002067
  16. Feb 2024
  17. 52.53.155.43 52.53.155.43
    AURKA enhances the glycolysis and development of ovarian endometriosis through ERβ
    1
    1. scibot 28 Feb 2024
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      DOI: 10.1210/endocr/bqae018

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    hnRNPA2B1 represses the disassembly of arsenite-induced stress granules and is essential for male fertility
    1
    1. scibot 24 Feb 2024
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    Dual roles of CCDC102A in governing centrosome duplication and cohesion
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    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113696

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    sciencedirect.com/science/article/pii/S221112472400024X
  20. Jan 2024
  21. www.sciencedirect.com www.sciencedirect.com
    Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells
    1
    1. scibot 25 Jan 2024
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    sciencedirect.com/science/article/pii/S1534580724000029
  22. Dec 2023
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    Grass carp reovirus VP56 and VP35 induce formation of viral inclusion bodies for replication
    1
    1. scibot 19 Dec 2023
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      DOI: 10.1016/j.isci.2023.108684

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    sciencedirect.com/science/article/pii/S258900422302761X
  24. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Glia-specific expression of neuropeptide receptor Lgr4 regulates development and adult physiology in Drosophila
    1
    1. scibot 15 Dec 2023
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      DOI: 10.1002/jnr.25271

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  25. Nov 2023
  26. www.sciencedirect.com www.sciencedirect.com
    A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113453

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    sciencedirect.com/science/article/pii/S2211124723014651
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    E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC
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    1. scibot 22 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113477

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    sciencedirect.com/science/article/pii/S2211124723014894
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    Transitional cell states sculpt tissue topology during lung regeneration
    1
    1. scibot 03 Nov 2023
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      DOI: 10.1016/j.stem.2023.10.001

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    sciencedirect.com/science/article/pii/S1934590923003636
  29. www.embopress.org www.embopress.org
    MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression
    1
    1. scibot 03 Nov 2023
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      DOI: 10.15252/embj.2023114558

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    embopress.org/doi/full/10.15252/embj.2023114558
  30. Oct 2023
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylated YBX2 is stabilized to promote glycolysis in brown adipocytes
    1
    1. scibot 20 Oct 2023
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      DOI: 10.1016/j.isci.2023.108091

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    ncbi.nlm.nih.gov/pmc/articles/PMC10583057/
  32. www.sciencedirect.com www.sciencedirect.com
    Gcn5- and Bre1-mediated Set2 degradation promotes chronological aging of Saccharomyces cerevisiae
    1
    1. scibot 13 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113186

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    sciencedirect.com/science/article/pii/S2211124723011981
  33. Sep 2023
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALKBH5-mediated m6A modification of HS3ST3B1-IT1 prevents osteoarthritis progression
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.isci.2023.107838

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    ncbi.nlm.nih.gov/pmc/articles/PMC10518728/
  35. www.nature.com www.nature.com
    Multi-omics profiling reveals rhythmic liver function shaped by meal timing
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      DOI: 10.1038/s41467-023-41759-9

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    nature.com/articles/s41467-023-41759-9
  36. www.sciencedirect.com www.sciencedirect.com
    Deciphering the functional landscape of phosphosites with deep neural network
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      DOI: 10.1016/j.celrep.2023.113048

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    sciencedirect.com/science/article/pii/S2211124723010598
  37. Aug 2023
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypermethylation of RNF125 promotes autophagy-induced oxidative stress in asthma by increasing HMGB1 stability
    1
    1. scibot 26 Aug 2023
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      DOI: 10.1016/j.isci.2023.107503

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    ncbi.nlm.nih.gov/pmc/articles/PMC10432822/
  39. 52.53.155.43 52.53.155.43
    LINC00116-Encoded Microprotein Mitoregulin Regulates Fatty Acid Metabolism at the Mitochondrial Outer Membrane
    1
    1. scibot 19 Aug 2023
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  40. 52.53.155.43 52.53.155.43
    LncRNA DGCR5-encoded polypeptide RIP aggravates SONFH by repressing nuclear localization of β-catenin in BMSCs
    2
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112969

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    2. scibot 16 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112969

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    52.53.155.43/65d236bbeb2359d9c37ad7ca2311e1cf29f548cc/PIIS2211124723009804-html.html
  41. Jul 2023
  42. 52.53.155.43 52.53.155.43
    GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner
    1
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      DOI: 10.15252/embr.202256437

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    An HBV susceptibility variant of KNG1 modulates the therapeutic effects of interferons α and λ1 in HBV infection by promoting MAVS lysosomal degradation
    1
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      DOI: 10.1016/j.ebiom.2023.104694

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    sciencedirect.com/science/article/pii/S2352396423002591
  44. Jun 2023
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycolytic enzyme HK2 promotes PD-L1 expression and breast cancer cell immune evasion
    1
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      DOI: 10.3389/fimmu.2023.1189953

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    ncbi.nlm.nih.gov/pmc/articles/PMC10291184/
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    Identification of XAF1 as an endogenous AKT inhibitor
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      DOI: 10.1016/j.celrep.2023.112690

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    sciencedirect.com/science/article/pii/S2211124723007015
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    Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal
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      DOI: 10.1016/j.isci.2023.107035

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    sciencedirect.com/science/article/pii/S2589004223011124
  48. www.sciencedirect.com www.sciencedirect.com
    A restrictor complex of ZC3H4, WDR82, and ARS2 integrates with PNUTS to control unproductive transcription
    1
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      DOI: 10.1016/j.molcel.2023.05.029

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    sciencedirect.com/science/article/pii/S1097276523003854
  49. www.sciencedirect.com www.sciencedirect.com
    Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity
    1
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      DOI: 10.1016/j.ccell.2023.05.005

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    sciencedirect.com/science/article/pii/S1535610823001733
  50. May 2023
  51. www.biorxiv.org www.biorxiv.org
    FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis
    1
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      DOI: 10.1101/2023.05.20.541585

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    biorxiv.org/content/10.1101/2023.05.20.541585v1
  52. www.sciencedirect.com www.sciencedirect.com
    MTHFD2 reprograms macrophage polarization by inhibiting PTEN
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      DOI: 10.1016/j.celrep.2023.112481

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    sciencedirect.com/science/article/pii/S2211124723004928
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tyrosine phosphorylation tunes chemical and thermal sensitivity of TRPV2 ion channel
    1
    1. scibot 05 May 2023
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      DOI: 10.7554/eLife.78301

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    ncbi.nlm.nih.gov/pmc/articles/PMC9282855/
  54. Apr 2023
  55. www.sciencedirect.com www.sciencedirect.com
    FXR1 regulates vascular smooth muscle cell cytoskeleton, VSMC contractility, and blood pressure by multiple mechanisms
    1
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      DOI: 10.1016/j.celrep.2023.112381

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    Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting
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  58. Mar 2023
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    EVL and MIM/MTSS1 regulate actin cytoskeletal remodeling to promote dendritic filopodia in neurons
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  62. Feb 2023
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    Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle
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    Structural insights into pathogenic mechanism of hypohidrotic ectodermal dysplasia caused by ectodysplasin A variants
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  65. Jan 2023
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    Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance
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    THOC5 complexes with DDX5, DDX17, and CDK12 to regulate R loop structures and transcription elongation rate
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    The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region
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    Lysine crotonylation regulates leucine-deprivation-induced autophagy by a 14-3-3ε-PPM1B axis
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  71. Oct 2022
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    A Novel NF2 Splicing Mutant Causes Neurofibromatosis Type 2 via Liquid-liquid Phase Separation with LATS and Hippo Pathway.
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  73. Aug 2022
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    S-palmitoylation of PCSK9 induces sorafenib resistance in liver cancer by activating the PI3K/AKT pathway
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    Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells
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    Native proline-rich motifs exploit sequence context to target actin-remodeling Ena/VASP protein ENAH
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    PTEN alleviates maladaptive repair of renal tubular epithelial cells by restoring CHMP2A-mediated phagosome closure
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    NRF1 association with AUTS2-Polycomb mediates specific gene activation in the brain
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  88. Sep 2021
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    Pantoprazole ameliorates liver fibrosis and suppresses hepatic stellate cell activation in bile duct ligation rats by promoting YAP degradation
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    Long noncoding RNA lnc-POP1-1 upregulated by VN1R5 promotes cisplatin resistance in head and neck squamous cell carcinoma through interaction with MCM5
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  91. Jul 2021
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  94. May 2021
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    SAS-6 Association with γ-Tubulin Ring Complex Is Required for Centriole Duplication in Human Cells
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    Nascent Pre-rRNA Sorting via Phase Separation Drives the Assembly of Dense Fibrillar Components in the Human Nucleolus
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    CCDC84 Acetylation Oscillation Regulates Centrosome Duplication by Modulating HsSAS-6 Degradation
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    FGF15 Activates Hippo Signaling to Suppress Bile Acid Metabolism and Liver Tumorigenesis
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