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Loss of the Asn333 high-mannose N-glycan impairs ACP3 folding and drives disease-associated dysfunction

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1. scibot 08 Oct 2026
  
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  DOI: 10.1016/j.isci.2026.117746
  
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sciencedirect.com/science/article/pii/S2589004226031275
Sep 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Functional matrix vesicle replacement partially restores chemo-mechanical coupling in the aged bone niche

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1. scibot 01 Sep 2026
  
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  DOI: 10.1016/j.xcrm.2026.102923
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13522752/
Aug 2026
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Hcp1 mediates multinucleated giant cell formation through redirecting arginine metabolism during Burkholderia pseudomallei infection

1
1. scibot 21 Aug 2026
  
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  DOI: 10.1016/j.celrep.2026.117868
  
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sciencedirect.com/science/article/pii/S2211124726009460
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Adipose GGPPS stabilizes BCAT2 to orchestrate BCAA catabolism and lipid mobilization in fasting-induced liver remodeling

1
1. scibot 18 Aug 2026
  
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  DOI: 10.1016/j.celrep.2026.117872
  
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sciencedirect.com/science/article/pii/S2211124726009502
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Torsins organize CLCC1 assembly to safeguard ER bilayer and lipid homeostasis

1
1. scibot 07 Aug 2026
  
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  DOI: 10.1016/j.molcel.2026.07.017
  
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sciencedirect.com/science/article/pii/S1097276526005034
Jul 2026
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Investigating the role of baseline gut Akkermansia muciniphila and its co-metabolite palmitoleic acid in BCG vaccine efficacy: a preclinical study

1
1. scibot 25 Jul 2026
  
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  DOI: 10.1016/j.ebiom.2026.106404
  
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sciencedirect.com/science/article/pii/S2352396426002884
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Aptamer targeting HMGB1 attenuates inflammatory disease via domain-specific antagonism

1
1. scibot 21 Jul 2026
  
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  DOI: 10.1016/j.chembiol.2026.06.011
  
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sciencedirect.com/science/article/pii/S2451945626002357
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DDIT3, OTUB2, and ASS1 regulate arginine biosynthesis in colorectal cancer cells under arginine deficiency

1
1. scibot 12 Jul 2026
  
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  DOI: 10.1016/j.celrep.2026.117621
  
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sciencedirect.com/science/article/pii/S2211124726006996
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FAM134B-mediated ER-phagy degrades APP and suppresses Alzheimer’s disease pathology

1
1. scibot 08 Jul 2026
  
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  DOI: 10.1038/s44318-026-00818-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13324857/
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Targeting cytokine-like protein FAM3D alleviates atherosclerosis

1
1. scibot 04 Jul 2026
  
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  DOI: 10.1016/j.xcrm.2026.102908
  
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sciencedirect.com/science/article/pii/S2666379126003253
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BPS Publications

1
1. scibot 03 Jul 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1111/bph.70518
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70518
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Lactate binds and inhibits the innate immune sensor STING to promote tumor immune evasion

1
1. scibot 03 Jul 2026
  
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  DOI: 10.1016/j.immuni.2026.06.004
  
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sciencedirect.com/science/article/pii/S1074761326002554
Jun 2026
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nsP3-FXR co-condensation enables alphavirus replication and reveals a targetable alphavirus vulnerability

1
1. scibot 05 Jun 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1016/j.celrep.2026.117495
  
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sciencedirect.com/science/article/pii/S2211124726005735
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NAT10-dependent N4-acetylcytidine reprograms R-loops and promotes cancer stem cell growth

1
1. scibot 04 Jun 2026
  
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  DOI: 10.1016/j.celrep.2026.117408
  
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sciencedirect.com/science/article/pii/S2211124726004869
May 2026
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USP52-RAB11FIP5 axis suppresses ferroptosis by repressing transferrin receptor recycling in head and neck squamous cell carcinoma

1
1. scibot 30 May 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1016/j.celrep.2026.117467
  
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sciencedirect.com/science/article/pii/S2211124726005450
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

OTUB2 induces M2 tumor-associated macrophage polarization and increases CD274 expression in gastric cancer cells to aggravate the progression of gastric cancer

1
1. scibot 29 May 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1038/s41419-026-08743-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13201613/
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Dual-system engineered bacteria and dendritic cells enable precise intratumoral IL-12 delivery and potent antitumor immunity

1
1. scibot 09 May 2026
  
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  DOI: 10.1016/j.xcrm.2026.102801
  
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sciencedirect.com/science/article/pii/S2666379126002181
Apr 2026
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USP15 stabilizes c-Myc to drive sunitinib resistance by suppressing cuproptosis in clear cell renal cell carcinoma

1
1. scibot 29 Apr 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1016/j.celrep.2026.117328
  
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sciencedirect.com/science/article/pii/S2211124726004067
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A skin-hypothalamus axis couples heat stress and metabolic dysfunction

1
1. scibot 24 Apr 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1016/j.cell.2026.03.045
  
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sciencedirect.com/science/article/pii/S0092867426003466
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TIMP1 Derived from Mesenchymal Stem Cells Promotes Bladder Cancer Progression by Regulating the Formation of VDIMs through the RAP1 Pathway

1
1. scibot 18 Apr 2026
  
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  RRID:AB_11232599
  
  DOI: 10.7150/ijbs.130720
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13085890/
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Cytoplasmic RNase III Drosha controls lipogenesis by noncanonical regulation of SREBP1

1
1. scibot 17 Apr 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1016/j.molcel.2026.03.028
  
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sciencedirect.com/science/article/pii/S1097276526002042
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BPS Publications

1
1. scibot 03 Apr 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1111/bph.70419
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70419
Mar 2026
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STUB1-VCP/p97 complex regulates mitophagy via fine-tuning of PINK1 levels

1
1. scibot 31 Mar 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1016/j.celrep.2026.117183
  
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sciencedirect.com/science/article/pii/S2211124726002615
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Cancer cell-derived sialylated IgG interacting with Siglec-7/9/10 is a potential immunotherapeutic target in pancreatic cancer

1
1. scibot 20 Mar 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1016/j.xcrm.2026.102660
  
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sciencedirect.com/science/article/pii/S2666379126000777
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TgFbox1-TgNAC2-TgWIN1 module regulates petal senescence by fine-tuning cuticular wax biosynthesis in tulip

1
1. scibot 17 Mar 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1016/j.celrep.2026.117100
  
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sciencedirect.com/science/article/pii/S2211124726001786
Feb 2026
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1-s2.0-S2589004226004293-main-html.html

1
1. scibot 19 Feb 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1016/j.isci.2026.115054
  
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cell.com/iscience/fulltext/S2589-0042(26)00429-3
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1-s2.0-S2589004226002919-main-html.html

1
1. scibot 12 Feb 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1016/j.isci.2026.114916
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12936848/
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Functional characterization of CASP, a CUX1 isoform, reveals its tumor-promoting role in colorectal cancer via TRIM21-mediated signaling

1
1. scibot 12 Feb 2026
  
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  DOI: 10.1016/j.isci.2026.114783
  
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sciencedirect.com/science/article/pii/S2589004226001586
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Delactylation of the tumor suppressor ARHGDIB drives metastasis and chemoresistance in bladder cancer

1
1. scibot 05 Feb 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1016/j.celrep.2026.116941
  
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sciencedirect.com/science/article/pii/S2211124726000197
Jan 2026
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Impaired PARP1-dependent DNA repair in MORC2 mutations drives axonal degeneration in Charcot-Marie-Tooth disease subtype 2Z and spinal muscular atrophy-like neuromotor disorders

1
1. scibot 22 Jan 2026
  
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  RRID:AB_1118269
  
  DOI: 10.1016/j.phrs.2026.108103
  
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sciencedirect.com/science/article/pii/S1043661826000186
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Ubiquitination and degradation of CD47 enhances macrophage phagocytosis of hemolytic erythrocytes

1
1. scibot 09 Jan 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1016/j.isci.2025.114499
  
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sciencedirect.com/science/article/pii/S2589004225027609
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Endometrial stromal cell-derived TMAO sustains decidualization to prevent recurrent spontaneous abortion

1
1. scibot 09 Jan 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1016/j.cmet.2025.11.014
  
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sciencedirect.com/science/article/pii/S1550413125005285
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Ubiquitination-directed cytosolic DNA degradation governs cGAS-STING-mediated immune response to DNA damage

1
1. scibot 09 Jan 2026
  
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  RRID:AB_11232599
  
  DOI: 10.1016/j.ccell.2025.12.013
  
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sciencedirect.com/science/article/pii/S1535610825005471
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

PSMD8 cooperates with USP14 to promote bladder cancer progression by inhibiting ferroptosis

1
1. scibot 19 Dec 2025
  
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  RRID:AB_11232599
  
  DOI: 10.1016/j.isci.2025.113938
  
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Potentiating immunotherapy in “immune-cold” solid tumors through orchestrating T cell immunity via tumor-specific genetic engineering

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Fatty acids modulate the colorectal cancer immune microenvironment via regulating the interaction and transactivation of PPARα/δ and P53

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Glutamine synthetase modulates YAP activation by stabilizing LATS under glutamine homeostasis

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Liquid-liquid phase separation of ATXN2L enhances mRNA translation in hepatocellular carcinoma

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1-s2.0-S2589004225021996-main-html.html

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Targeting USP21 to inhibit abdominal aortic aneurysm progression by suppressing the phenotypic transition of vascular smooth muscle cells

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Tobacco Smoking Rewires Cell Metabolism by Inducing GAPDH Succinylation to Promote Lung Cancer Progression

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RFX2-BNIP3 axis-driven adaptive mitophagy promotes resistance to ACK1-targeted therapy in non-small cell lung cancer

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Alistipes finegoldii augments the efficacy of immunotherapy against solid tumors

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Cardiomyocyte-derived YOD1 promotes pathological cardiac hypertrophy by deubiquitinating and stabilizing STAT3

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Cardiomyocyte-derived YOD1 promotes pathological cardiac hypertrophy by deubiquitinating and stabilizing STAT3

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Arachidonic acid triggers spermidine synthase secretion from primary tumor to induce skeletal muscle weakness upon irradiation

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Foxp3 confers long-term efficacy of chimeric antigen receptor-T cells via metabolic reprogramming

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Integrase enables synthetic intercellular logic via bacterial conjugation

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THBS2-producing matrix CAFs promote colorectal cancer progression and link to poor prognosis via the CD47-MAPK axis

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LAMP2A-mediated neuronal hyperexcitability by enhancing NKAβ1 degradation underlies depression-induced allodynia

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Hypoxia-induced PRMT1 methylates HIF2β to promote breast tumorigenesis via enhancing glycolytic gene transcription

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PI3Kβ functions as a protein kinase to promote cellular protein O-GlcNAcylation and acetyl-CoA production for tumor growth

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Lactylation of LSD1 is an acquired epigenetic vulnerability of BRAFi/MEKi-resistant melanoma

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Nuclear-localized HKDC1 promotes hepatocellular carcinoma through phosphorylating RBBP5 to upregulate H3K4me3

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OXCT1 succinylation and activation by SUCLA2 promotes ketolysis and liver tumor growth

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Itaconate transporter SLC13A3 confers immunotherapy resistance via alkylation-mediated stabilization of PD-L1

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Gut microbiota protect against colorectal tumorigenesis through lncRNA Snhg9

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Elevated IL-22 as a result of stress-induced gut leakage suppresses septal neuron activation to ameliorate anxiety-like behavior

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Probiotics-sensing mechanism in neurons that initiates gut mitochondrial surveillance for pathogen defense

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Sirtuin 1/sirtuin 3 are robust lysine delactylases and sirtuin 1-mediated delactylation regulates glycolysis

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HSV-1-induced N6-methyladenosine reprogramming via ICP0-mediated suppression of METTL14 potentiates oncolytic activity in glioma

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A broad-spectrum multiepitope vaccine against seasonal influenza A and B viruses in mice

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ST6GALNAC1-mediated sialylation in uterine endometrial epithelium facilitates the epithelium-embryo attachment

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Ca<sup>2+</sup> entry through mechanotransduction channels localizes BAIAP2L2 to stereocilia tips

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  DOI: 10.1091/mbc.E21-10-0491
  
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Rpsa Signaling Regulates Cortical Neuronal Morphogenesis via Its Ligand, PEDF, and Plasma Membrane Interaction Partner, Itga6

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Oncogenic fatty acid oxidation senses circadian disruption in sleep-deficiency-enhanced tumorigenesis

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Dimethyl fumarate covalently modifies Cys673 of NLRP3 to exert anti-inflammatory effects

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Mar 2024
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ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat

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  DOI: 10.1016/j.cell.2024.02.013
  
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Feb 2024
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ATG5 attenuates inflammatory signaling in mouse embryonic stem cells to control differentiation

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Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men

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A SUMO E3 ligase promotes long non-coding RNA transcription to regulate small RNA-directed DNA elimination

1
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Suppression of Drosophila antifungal immunity by a parasite effector via blocking GNBP3 and GNBP-like 3, the dual receptors for β-glucans

1
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FLOT2 promotes nasopharyngeal carcinoma progression through suppression of TGF-β pathway via facilitating CD109 expression

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E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC

1
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MST2 methylation by PRMT5 inhibits Hippo signaling and promotes pancreatic cancer progression

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  DOI: 10.15252/embj.2023114558
  
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The yeast protein Ure2p triggers Tau pathology in a mouse model of tauopathy

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Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5

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Sep 2023
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The PtdIns3P phosphatase MtMP promotes symbiotic nitrogen fixation via mitophagy in Medicago truncatula

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Aug 2023
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Inhibition of FNDC1 suppresses gastric cancer progression by interfering with Gβγ-VEGFR2 complex formation

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C1orf112 teams up with FIGNL1 to facilitate RAD51 filament disassembly and DNA interstrand cross-link repair

1
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PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARγ

1
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  DOI: 10.2337/db22-1016
  
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Jun 2023
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Integrated regulation of tubulin tyrosination and microtubule stability by human α-tubulin isotypes

1
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  DOI: 10.1016/j.celrep.2023.112653
  
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May 2023
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Cathepsin K promotes the proliferation of hepatocellular carcinoma cells through induction of SIAH1 ubiquitination and degradation

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  DOI: 10.1016/j.isci.2023.106852
  
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Apr 2023
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VMP1 affects endoplasmic reticulum stress sensitivity via differential modulation of the three unfolded protein response arms

1
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  DOI: 10.1016/j.celrep.2023.112209
  
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Feb 2023
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Cofilin promotes tau pathology in Alzheimer’s disease

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  DOI: 10.1016/j.celrep.2023.112138
  
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Structurally distinct PARP7 inhibitors provide new insights into the function of PARP7 in regulating nucleic acid-sensing and IFN-β signaling

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  DOI: 10.1016/j.chembiol.2022.11.012
  
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Sensing of a spore surface protein by a Drosophila chemosensory protein induces behavioral defense against fungal parasitic infections

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  DOI: 10.1016/j.cub.2022.11.004
  
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circPRKAA1 activates a Ku80/Ku70/SREBP-1 axis driving de novo fatty acid synthesis in cancer cells

1
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  DOI: 10.1016/j.celrep.2022.111707
  
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Oct 2022
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Argininosuccinate lyase drives activation of mutant TERT promoter in glioblastomas

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  DOI: 10.1016/j.molcel.2022.09.024
  
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Rabphilin 3A binds the N-peptide of SNAP-25 to promote SNARE complex assembly in exocytosis

2
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  DOI: 10.7554/eLife.79926
  
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Aug 2022
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An anillin-CIN85-SEPT9 complex promotes intercellular bridge maturation required for successful cytokinesis

1
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Ubiquitination of phosphatidylethanolamine in organellar membranes

1
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  DOI: 10.1016/j.molcel.2022.08.008
  
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Apr 2022
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Ca2+ entry through mechanotransduction channels localizes BAIAP2L2 to stereocilia tips

1
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  DOI: 10.1091/mbc.E21-10-0491
  
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Mar 2022
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Fumarate inhibits PTEN to promote tumorigenesis and therapeutic resistance of type2 papillary renal cell carcinoma

1
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  DOI: 10.1016/j.molcel.2022.01.029
  
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BPS Publications

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  DOI: 10.1111/bph.15801
  
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Nov 2021
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A nonautophagic role of ATG5 in regulating cell growth by targeting c-Myc for proteasome-mediated degradation

1
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  DOI: 10.1016/j.isci.2021.103296
  
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Jul 2021
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LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis

1
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  DOI: 10.1016/j.cell.2019.07.021
  
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academic.oup.com academic.oup.com

Female-to-male sex reversal in orange-spotted grouper (Epinephelus coioides) caused by overexpressing of Amh in vivo

1
1. scibot 28 Jul 2021
  
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  AB_11 232 599
  
  DOI: 10.1093/biolre/ioy157
  
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academic.oup.com/biolreprod/advance-article/doi/10.1093/biolre/ioy157/5053798
May 2021
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Amphiphysin I cleavage by asparagine endopeptidase leads to tau hyperphosphorylation and synaptic dysfunction

1
1. scibot 27 May 2021
  
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  DOI: 10.7554/eLife.65301
  
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Feb 2021
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ALS-causing SOD1 mutants regulate occludin phosphorylation/ubiquitination and endocytic trafficking via the ITCH/Eps15/Rab5 axis

1
1. scibot 25 Feb 2021
  
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  His
  
  DOI: 10.1016/j.nbd.2021.105315
  
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sciencedirect.com/science/article/pii/S0969996121000644
Sep 2020
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Enhancer RNAs Mediate Estrogen-Induced Decommissioning of Selective Enhancers by Recruiting ERα and Its Cofactor

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1. scibot 07 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107803
  
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sciencedirect.com/science/article/pii/S2211124720307841
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lncRNA Sensing of a Viral Suppressor of RNAi Activates Non-canonical Innate Immune Signaling in Drosophila

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  DOI: 10.1016/j.chom.2019.12.006
  
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LECT2, a Ligand for Tie1, Plays a Crucial Role in Liver Fibrogenesis

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  DOI: 10.1016/j.cell.2019.07.021
  
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Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection

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  DOI: 10.1016/j.immuni.2019.11.015
  
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Untitled document

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  DOI: 10.1016/j.celrep.2019.01.030
  
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Female-to-male sex reversal in orange-spotted grouper (Epinephelus coioides) caused by overexpressing of Amh in vivo

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  DOI: 10.1093/biolre/ioy157
  
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Untitled document

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  DOI: 10.7554/eLife.42426
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6361614/
Nov 2018
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GRASP55 Senses Glucose Deprivation through O-GlcNAcylation to Promote Autophagosome-Lysosome Fusion

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Structural Insights into the pH-Dependent Conformational Change and Collagen Recognition of the Human Mannose Receptor

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Nov 2017
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SIRT1 Functions as a Negative Regulator of Eukaryotic Poly(A)RNA Transport

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sciencedirect.com/science/article/pii/S0960982217307777

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