115 Matching Annotations
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    Ubiquitin chain editing promotes p97/VCP-dependent removal of RPA from DNA
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    sciencedirect.com/science/article/pii/S1097276526006210
  3. Oct 2026
  4. www.cell.com www.cell.com
    Targeted O-GlcNAcylation enables functional rewiring of c-Myc
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    cell.com/cell-chemical-biology/abstract/S2451-9456(26)00318-1
  5. Sep 2026
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    Exercise-induced adipose tissue ADRB2-PGC1α-FGF21 signaling protects against pathological cardiac hypertrophy
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    sciencedirect.com/science/article/pii/S2589004226027987
  7. Jul 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-wide CRISPR screen identifies AMBRA1 as a potential biomarker of response to platinum-based therapies in oral squamous cell carcinomas
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    pmc.ncbi.nlm.nih.gov/articles/PMC13429904/
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    The Legionella pneumophila effector SidL is an adenylyltransferase that modifies the glycolytic intermediate 3-phosphoglycerate
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    sciencedirect.com/science/article/pii/S1097276526004715
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    Nilotinib induces immunogenic cuproptosis to potentiate cancer immunotherapy
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    sciencedirect.com/science/article/pii/S2666379126003459
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    11-Oxygenated Androgens Inhibit Brown Adipose Tissue Differentiation
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    dx.doi.org/10.1210/endocr/bqaf172
  12. Jun 2026
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    Single kinetochores execute an ordered series of molecular events as the spindle assembly checkpoint is silenced
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  14. May 2026
  15. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    The Host Cell Factor Phosphatase-2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type-1
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202523697
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    Genetic variation reveals a homeotic long noncoding RNA that modulates human hematopoietic stem cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13138457/
  17. Apr 2026
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SNAT1 (SLC38A1) Is Not the Main Glutamine Transporter in Melanoma, but Controls Metabolism via Glutamine-Dependent Activation of P62 (SQSTM1)/cMYC-Axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13072269/
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    Wntless degradation mediated by CaMKII inhibition drives endoplasmic reticulum stress and apoptosis
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    Nutrient Availability Dictates Cancer Metabolism–Based Therapeutic Responses to Nononcology Drugs
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    pmc.ncbi.nlm.nih.gov/articles/PMC13055633/
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    Dual-site phosphorylation of SLX4 stabilizes the SLX4–MUS81 interface to promote mitotic SMX assembly and genome protection
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    dx.doi.org/10.1093/nar/gkag195
  22. Mar 2026
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    RNF25 confers mRNA damage tolerance by curbing activation of the integrated stress response
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    sciencedirect.com/science/article/pii/S1097276526001383
  24. Feb 2026
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metabolic control of innate immune activation in TET2-mutant clonal hematopoiesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12933725/
  26. Jan 2026
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The endocrine disruptor chlorpyrifos alters hypothalamic Npy and Agrp expression via ERβ-dependent regulation in vitro and in vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC12846974/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pyroptosis modulates multiple immune cell populations in targeted therapy–treated melanoma
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    Ubiquitination-directed cytosolic DNA degradation governs cGAS-STING-mediated immune response to DNA damage
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    sciencedirect.com/science/article/pii/S1535610825005471
  30. Dec 2025
  31. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    An organotypic model of ductular reaction reveals a mevalonate-dependent vulnerability in reactive biliary cells
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    Recruitment of FBXO22 for targeted degradation of NSD2
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    pmc.ncbi.nlm.nih.gov/articles/PMC11581931/
  33. Nov 2025
  34. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Glutamine synthetase modulates YAP activation by stabilizing LATS under glutamine homeostasis
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  35. Oct 2025
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nuclear Galectin-1 promotes KRAS-dependent activation of pancreatic cancer stellate cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12002210/
  37. Sep 2025
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elevated Transglutaminase-2 in SOX10-Deficient Melanoma Promotes Tumor Onset and Decreases Intratumoral CD4+ T Cells
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  39. 52.53.155.43 52.53.155.43
    2025.08.22.671484v1.full-html.html
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  40. Aug 2025
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrated real-time imaging of executioner caspase dynamics, apoptosis-induced proliferation, and immunogenic cell death using a stable fluorescent reporter platform
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  42. Jul 2025
  43. www.cell.com www.cell.com
    TIM3+ breast cancer cells license immune evasion during micrometastasis outbreak
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    cell.com/cancer-cell/abstract/S1535-6108(25)00265-X
  44. Jun 2025
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    Vault RNAs aid RNA virus infection by facilitating cytoplasmic localization of hnRNP C and ELAVL1
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  46. May 2025
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CDK4/6 activity is required during G2 arrest to prevent stress induced endoreplication
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    Generation of a human embryonic stem cell line (WAe009-A-3B) carrying homozygous TNNT2 gene knockout by CRISPR/Cas9 editing
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    TAF2 condensation in nuclear speckles links basal transcription factor TFIID to RNA splicing factors
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  50. Mar 2025
  51. www.cell.com www.cell.com
    Isogenic comparison of Airn and Xist reveals core principles of Polycomb recruitment by lncRNAs
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  52. Feb 2025
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    Translesion-synthesis-mediated bypass of DNA lesions occurs predominantly behind replication forks restarted by PrimPol
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    The integrated stress response regulates 18S nonfunctional rRNA decay in mammals
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    RIOK3 mediates the degradation of 40S ribosomes
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  56. Jan 2025
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    Itaconate transporter SLC13A3 confers immunotherapy resistance via alkylation-mediated stabilization of PD-L1
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    Targeting N-Myc in neuroblastoma with selective Aurora kinase A degraders
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  59. Dec 2024
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    Increased nuclear factor I-mediated chromatin access drives transition to androgen receptor splice variant dependence in prostate cancer
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    METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in neuroblastoma
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  62. Nov 2024
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    Altered sphingolipid biosynthetic flux and lipoprotein trafficking contribute to trans-fat-induced atherosclerosis
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    Degradome analysis to identify direct protein substrates of small-molecule degraders
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  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dynamic roles of neutrophil extracellular traps in cancer cell adhesion and activation of Notch 1-mediated epithelial-to-mesenchymal transition in EGFR-driven lung cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11487346/
  66. Sep 2024
  67. academic.oup.com academic.oup.com
    BRAF-induced EHF Expression Affects TERT in Aggressive Papillary Thyroid Cancer
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  68. Aug 2024
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    Microgravity Induces Transient EMT in Human Keratinocytes by Early Down-Regulation of E-Cadherin and Cell-Adhesion Remodeling
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  70. Jul 2024
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    Identification of the main barriers to Ku accumulation in chromatin
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    TP53INP2-dependent activation of muscle autophagy ameliorates sarcopenia and promotes healthy aging
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    A highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer
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    FANCM promotes PARP inhibitor resistance by minimizing ssDNA gap formation and counteracting resection inhibition
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    Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling
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  76. analyticalsciencejournals.onlinelibrary.wiley.com analyticalsciencejournals.onlinelibrary.wiley.com
    Label-free three-dimensional imaging and quantitative analysis of living fibroblasts and myofibroblasts by holotomographic microscopy
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    analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/jemt.24648
  77. Jun 2024
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    Electro-elution-based purification of covalent DNA–protein cross-links
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    An integrative epigenome-based strategy for unbiased functional profiling of clinical kinase inhibitors
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    The ribotoxic stress response drives UV-mediated cell death
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  81. May 2024
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    Glucose-driven histone lactylation promotes the immunosuppressive activity of monocyte-derived macrophages in glioblastoma
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    CDK4/6 activity is required during G2 arrest to prevent stress-induced endoreplication
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    PRMT1 promotes epigenetic reprogramming associated with acquired chemoresistance in pancreatic cancer
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  85. Apr 2024
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    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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    Mutant FOXO1 controls an oncogenic network via enhancer accessibility
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  88. Mar 2024
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    Acetyl-CoA production by Mediator-bound 2-ketoacid dehydrogenases boosts de novo histone acetylation and is regulated by nitric oxide
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  90. Feb 2024
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    Identification of a First-in-Class Small Molecule Inhibitor of the eIF4E-RBM38 Complex that Enhances wild-type p53 Protein Translation for Tumor Growth Suppression
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    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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    biorxiv.org/content/10.1101/2023.12.05.570182v1
  93. Nov 2023
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    RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks
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    Recruitment of FBXO22 for Targeted Degradation of NSD2
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    SIRT2 negatively regulates the cGAS-STING pathway by deacetylating G3BP1
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    embopress.org/doi/10.15252/embr.202357500
  97. Oct 2023
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    Human MCTS1-dependent translation of JAK2 is essential for IFN-γ immunity to mycobacteria
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    Universal features of Nsp1-mediated translational shutdown by coronaviruses
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    Targeting LYPLAL1-mediated cGAS depalmitoylation enhances the response to anti-tumor immunotherapy
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    ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct
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  102. Aug 2023
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    The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway
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  104. Jul 2023
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    Mapping Pregnancy-dependent Sulfhydrome Unfolds Diverse Functions of Protein Sulfhydration in Human Uterine Artery
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    Macrophage-mediated extracellular matrix remodeling controls host Staphylococcus aureus susceptibility in the skin
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  107. Jun 2023
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    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
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    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
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  111. May 2023
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    ALDH1L2 regulation of formate, formyl-methionine, and ROS controls cancer cell migration and metastasis
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  113. Apr 2023
  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC10102842/
  115. Feb 2023
  116. aacrjournals.org aacrjournals.org
    Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling
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    aacrjournals.org/cancerres/article/83/2/219/715076/Plk1-Inhibitors-and-Abiraterone-Synergistically
  117. Jan 2023
  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9298960/
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    The human pre-replication complex is an open complex
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  120. Dec 2022
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    Raptinal induces Gasdermin E-dependent pyroptosis in naive and therapy-resistant melanoma
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    aacrjournals.org/mcr/article/20/12/1811/711004/Raptinal-Induces-Gasdermin-E-Dependent-Pyroptosis
  122. Nov 2022
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437574/
  124. Oct 2022
  125. 52.53.155.43 52.53.155.43
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  126. Aug 2022
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