114 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transient proliferation by reversible YAP and mitogen control of the cyclin D1/p27 ratio
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    pmc.ncbi.nlm.nih.gov/articles/PMC12957376/
  3. Mar 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Eukaryote initiation factor 6 modulates small-cell lung carcinoma plasticity via the integrin-FAK signaling axis
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  5. Feb 2026
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    Hypoxia restores the acidosis-induced inhibition of cancer cell dissemination
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    sciencedirect.com/science/article/pii/S2211124726000483
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    ARHGEF17/TEM4 regulates the cell cycle through control of G1 progression
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    Male-biased Yap1-Cd276/B7-H3 axis for immune evasion in medulloblastoma
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    sciencedirect.com/science/article/pii/S1535610826000449
  9. Jan 2026
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    Mitochondria-targeted antioxidant AntiOxBEN2 prevents metabolic dysfunction-associated steatotic liver disease (MASLD) by enhancing fatty acid oxidation and mitochondrial bioenergetics
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    sciencedirect.com/science/article/pii/S0753332226000545
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    Improving Nonviral Gene Delivery by Activating Mechanosensing-Dependent Endocytic Pathways
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    pubs.acs.org/doi/full/10.1021/acsami.5c23767
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    Protocol to identify mechanosensitive nuclear proteins using tunable actomyosin contractility and proximity biotinylation in mammalian cells
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    sciencedirect.com/science/article/pii/S266616672500694X
  13. Dec 2025
  14. 54.241.53.176 54.241.53.176
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    Membrane potential mediates the cellular response to mechanical pressure
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  16. Nov 2025
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    Glutamine synthetase modulates YAP activation by stabilizing LATS under glutamine homeostasis
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    Intermediate filaments promote glioblastoma cell invasion by controlling nuclear deformations and mechanosensitive expression of MMP14
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  19. Oct 2025
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    CANDiT: A machine learning framework for differentiation therapy in colorectal cancer
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  21. Sep 2025
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    Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state
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    sciencedirect.com/science/article/pii/S2211124725009568
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    Mechanosensitive calcium channels and integrins coordinate the reprogramming of colorectal cancer cells into a fetal-like state
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    sciencedirect.com/science/article/pii/S2211124725010794
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    Stress and obesity signaling converge on CREB phosphorylation to promote pancreatic cancer
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    Endogenous YAP/TAZ partitioning in TEAD condensates orchestrates the Hippo response
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    sciencedirect.com/science/article/pii/S1097276525006641
  26. Jul 2025
  27. www.embopress.org www.embopress.org
    Hippo pathway controls biopterin metabolism to shield adjacent cells from ferroptosis in lung cancer
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    Oxidative stress and Kras mutation in Mist1+ cells act in a double-hit manner to drive gastric tumorigenesis
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  29. Jun 2025
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    RIPK4 promotes epidermal differentiation through phase separation and activation of LATS1/2
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  32. May 2025
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    YAP1 promoter-associated noncoding RNA affects Ewing sarcoma cell tumorigenicity by regulating YAP1 expression
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    Extracellular matrix mechanical cues (dys)regulate metabolic redox homeostasis due to impaired autophagic flux
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    onlinelibrary.wiley.com/doi/10.1111/eci.70051
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    A retinoic acid:YAP1 signaling axis controls atrial lineage commitment
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    Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target
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  37. Apr 2025
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  39. Feb 2025
  40. aacrjournals.org aacrjournals.org
    Peptide PDHPS1 inhibits ovarian cancer growth through disrupting YAP signaling
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    aacrjournals.org/mct/article/21/7/1160/705294/Peptide-PDHPS1-Inhibits-Ovarian-Cancer-Growth
  41. Jan 2025
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  43. Dec 2024
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BMP suppresses Wnt signaling via the Bcl11b-regulated NuRD complex to maintain intestinal stem cells
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  45. Sep 2024
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Review Commons Transfer: Nucleocytoplasmic transport senses mechanical forces independently of cell density in cell monolayers
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    Netrin-1 and UNC5B Cooperate with Integrins to Mediate YAP-Driven Cytostasis
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  48. Jun 2024
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    Nonlinear Elastic Bottlebrush Polymer Hydrogels Modulate Actomyosin Mediated Protrusion Formation in Mesenchymal Stromal Cells
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    onlinelibrary.wiley.com/doi/10.1002/adma.202403198
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    DNA-based ForceChrono probes for deciphering single-molecule force dynamics in living cells
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    Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress
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  52. May 2024
  53. www.biorxiv.org www.biorxiv.org
    Nucleocytoplasmic transport senses mechanics independently of cell density in cell monolayers
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    biorxiv.org/content/10.1101/2024.01.11.575167v1
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    Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease
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  55. Apr 2024
  56. rupress.org rupress.org
    WW domains form a folded type of nuclear localization signal to guide YAP1 nuclear import
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    rupress.org/jcb/article/223/6/e202308013/276631/WW-domains-form-a-folded-type-of-nuclear
  57. Feb 2024
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    YAP mediates apoptosis through failed integrin adhesion reinforcement
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    Volumetric Compression Shifts Rho GTPase Balance and Induces Mechanobiological Cell State Transition
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    3D matrix adhesion feedback controls nuclear force coupling to drive invasive cell migration
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  61. Dec 2023
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    Cell stretching activates an ATM mechano-transduction pathway that remodels cytoskeleton and chromatin
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  63. Nov 2023
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acid-base homeostasis orchestrated by NHE1 defines the pancreatic stellate cell phenotype in pancreatic cancer
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  65. Oct 2023
  66. www.science.org www.science.org
    Piezo1 activates noncanonical EGFR endocytosis and signaling
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    Piezo1 activates noncanonical EGFR endocytosis and signaling
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  68. Sep 2023
  69. www.sciencedirect.com www.sciencedirect.com
    LSR targets YAP to modulate intestinal Paneth cell differentiation
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  70. Jul 2023
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    Targeting ITGB4/SOX2-driven lung cancer stem cells using proteasome inhibitors
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    MAP4Ks inhibition promotes retinal neuron regeneration from Müller glia in adult mice
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    nature.com/articles/s41536-023-00310-6
  73. Jun 2023
  74. www.sciencedirect.com www.sciencedirect.com
    Epithelial tissue confinement inhibits cell growth and leads to volume-reducing divisions
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  75. May 2023
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    LAPTM4B-YAP loop feedback amplification enhances the stemness of hepatocellular carcinoma
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    Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment
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  78. Feb 2023
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    Actin crosslinking by α-actinin averts viscous dissipation of myosin force transmission in stress fibers
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    The developmental basis of fingerprint pattern formation and variation
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    cell.com/cell/fulltext/S0092-8674(23)00045-4
  81. Jan 2023
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC9630827/
  83. Sep 2022
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    Virtual screening for small-molecule pathway regulators by image-profile matching
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  85. Aug 2022
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    Neuronal paxillin and drebrin mediate BDNF-induced force transduction and growth cone turning in a soft-tissue-like environment
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  87. Jun 2022
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  89. Apr 2022
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    WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy
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  91. Mar 2022
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    Counteractive and cooperative actions of muscle β-catenin and CaV1.1 during early neuromuscular synapse formation
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  93. Feb 2022
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bidirectional Crosstalk between MAOA and AR Promotes Hormone-Dependent and Castration-Resistant Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8373824/
  95. Jan 2022
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    Multi-omic analysis reveals divergent molecular events in scarring and regenerative wound healing
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  97. Oct 2021
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    Lentiviral-mediated ectopic expression of YAP and TAZ in YAPoff cancer cell lines
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  99. Aug 2021
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    Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity
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    Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis
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    sciencedirect.com/science/article/pii/S2211124721010342
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    Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
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  107. Jul 2021
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    Yap and its subcellular localization have distinct compartment-specific roles in the developing lung
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  110. elifesciences.org elifesciences.org
    Transitions in cell potency during early mouse development are driven by Notch
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    YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis
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    Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity
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  113. Jun 2021
  114. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    TNIK is a therapeutic target in Lung Squamous Cell Carcinoma and regulates FAK activation through Merlin.
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    cancerdiscovery.aacrjournals.org/content/11/6/1411
  115. May 2021
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    Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation
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  117. Apr 2021
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    Cell intercalation driven by SMAD3 underlies secondary neural tube formation
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    Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer
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  120. Mar 2021
  121. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    The tumor suppressor LATS2 reduces v‐Src‐induced membrane blebs in a kinase activity‐independent manner
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202001909R
  122. Feb 2021
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporal control of phosphatidic acid signaling with optogenetic, engineered phospholipase Ds
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    ncbi.nlm.nih.gov/pmc/articles/PMC7054994/
  124. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Suppression of adipocyte differentiation by low‐intensity pulsed ultrasound via inhibition of insulin signaling and promotion of CCN family protein 2
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    onlinelibrary.wiley.com/doi/10.1002/jcb.29680
  125. Sep 2020
  126. www.sciencedirect.com www.sciencedirect.com
    Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair
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    Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis
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    MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation
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    Osmotic Gradients in Epithelial Acini Increase Mechanical Tension across E-cadherin, Drive Morphogenesis, and Maintain Homeostasis
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