97 Matching Annotations
  1. Jul 2025
  2. www.embopress.org www.embopress.org
    Hippo pathway controls biopterin metabolism to shield adjacent cells from ferroptosis in lung cancer
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    embopress.org/doi/10.1038/s44319-025-00515-4
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    Oxidative stress and Kras mutation in Mist1+ cells act in a double-hit manner to drive gastric tumorigenesis
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    sciencedirect.com/science/article/pii/S2211124725007855
  4. Jun 2025
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    RIPK4 promotes epidermal differentiation through phase separation and activation of LATS1/2
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    sciencedirect.com/science/article/pii/S1534580725003284
  6. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/9cdde814e7de824838c1017824753184462e213e/PDF-html.html
  7. May 2025
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    YAP1 promoter-associated noncoding RNA affects Ewing sarcoma cell tumorigenicity by regulating YAP1 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12103783/
  9. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Extracellular matrix mechanical cues (dys)regulate metabolic redox homeostasis due to impaired autophagic flux
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    onlinelibrary.wiley.com/doi/10.1111/eci.70051
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    A retinoic acid:YAP1 signaling axis controls atrial lineage commitment
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    sciencedirect.com/science/article/pii/S2211124725004589
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    Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target
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    sciencedirect.com/science/article/pii/S1535610825001734
  12. Apr 2025
  13. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225005346-main-html.html
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  14. Feb 2025
  15. aacrjournals.org aacrjournals.org
    Peptide PDHPS1 inhibits ovarian cancer growth through disrupting YAP signaling
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    aacrjournals.org/mct/article/21/7/1160/705294/Peptide-PDHPS1-Inhibits-Ovarian-Cancer-Growth
  16. Jan 2025
  17. 52.53.155.43 52.53.155.43
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  18. Dec 2024
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BMP suppresses Wnt signaling via the Bcl11b-regulated NuRD complex to maintain intestinal stem cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11612440/
  20. Sep 2024
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Review Commons Transfer: Nucleocytoplasmic transport senses mechanical forces independently of cell density in cell monolayers
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    ncbi.nlm.nih.gov/pmc/articles/PMC11423809/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin-1 and UNC5B Cooperate with Integrins to Mediate YAP-Driven Cytostasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11384508/
  23. Jun 2024
  24. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nonlinear Elastic Bottlebrush Polymer Hydrogels Modulate Actomyosin Mediated Protrusion Formation in Mesenchymal Stromal Cells
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    onlinelibrary.wiley.com/doi/10.1002/adma.202403198
  25. www.sciencedirect.com www.sciencedirect.com
    DNA-based ForceChrono probes for deciphering single-molecule force dynamics in living cells
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    sciencedirect.com/science/article/pii/S0092867424005178
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress
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    ncbi.nlm.nih.gov/pmc/articles/PMC11140209/
  27. May 2024
  28. www.biorxiv.org www.biorxiv.org
    Nucleocytoplasmic transport senses mechanics independently of cell density in cell monolayers
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    biorxiv.org/content/10.1101/2024.01.11.575167v1
  29. www.sciencedirect.com www.sciencedirect.com
    Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease
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    sciencedirect.com/science/article/pii/S1934590924001292
  30. Apr 2024
  31. rupress.org rupress.org
    WW domains form a folded type of nuclear localization signal to guide YAP1 nuclear import
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    rupress.org/jcb/article/223/6/e202308013/276631/WW-domains-form-a-folded-type-of-nuclear
  32. Feb 2024
  33. www.sciencedirect.com www.sciencedirect.com
    YAP mediates apoptosis through failed integrin adhesion reinforcement
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    sciencedirect.com/science/article/pii/S2211124724001396
  34. 52.53.155.43 52.53.155.43
    Volumetric Compression Shifts Rho GTPase Balance and Induces Mechanobiological Cell State Transition
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    3D matrix adhesion feedback controls nuclear force coupling to drive invasive cell migration
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    sciencedirect.com/science/article/pii/S2211124723015668
  36. Dec 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Cell stretching activates an ATM mechano-transduction pathway that remodels cytoskeleton and chromatin
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  38. Nov 2023
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acid-base homeostasis orchestrated by NHE1 defines the pancreatic stellate cell phenotype in pancreatic cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10619433/
  40. Oct 2023
  41. www.science.org www.science.org
    Piezo1 activates noncanonical EGFR endocytosis and signaling
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    science.org/doi/10.1126/sciadv.adi1328
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Piezo1 activates noncanonical EGFR endocytosis and signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC10530101/
  43. Sep 2023
  44. www.sciencedirect.com www.sciencedirect.com
    LSR targets YAP to modulate intestinal Paneth cell differentiation
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    sciencedirect.com/science/article/pii/S2211124723011300
  45. Jul 2023
  46. www.sciencedirect.com www.sciencedirect.com
    Targeting ITGB4/SOX2-driven lung cancer stem cells using proteasome inhibitors
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    sciencedirect.com/science/article/pii/S2589004223013792
  47. www.nature.com www.nature.com
    MAP4Ks inhibition promotes retinal neuron regeneration from Müller glia in adult mice
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    nature.com/articles/s41536-023-00310-6
  48. Jun 2023
  49. www.sciencedirect.com www.sciencedirect.com
    Epithelial tissue confinement inhibits cell growth and leads to volume-reducing divisions
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    sciencedirect.com/science/article/pii/S1534580723002666
  50. May 2023
  51. www.sciencedirect.com www.sciencedirect.com
    LAPTM4B-YAP loop feedback amplification enhances the stemness of hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2589004223008313
  52. www.sciencedirect.com www.sciencedirect.com
    Extracellular vesicles in fatty liver promote a metastatic tumor microenvironment
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    sciencedirect.com/science/article/pii/S1550413123001407
  53. Feb 2023
  54. www.sciencedirect.com www.sciencedirect.com
    Actin crosslinking by α-actinin averts viscous dissipation of myosin force transmission in stress fibers
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    sciencedirect.com/science/article/pii/S2589004223001670
  55. www.cell.com www.cell.com
    The developmental basis of fingerprint pattern formation and variation
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    cell.com/cell/fulltext/S0092-8674(23)00045-4
  56. Jan 2023
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Opposite Effects of Src Family Kinases on YAP and ERK Activation in Pancreatic Cancer Cells: Implications for Targeted Therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC9630827/
  58. Sep 2022
  59. www.sciencedirect.com www.sciencedirect.com
    Virtual screening for small-molecule pathway regulators by image-profile matching
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    sciencedirect.com/science/article/pii/S2405471222003301
  60. Aug 2022
  61. www.sciencedirect.com www.sciencedirect.com
    Neuronal paxillin and drebrin mediate BDNF-induced force transduction and growth cone turning in a soft-tissue-like environment
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    sciencedirect.com/science/article/pii/S2211124722010051
  62. Jun 2022
  63. 52.53.155.43 52.53.155.43
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  64. Apr 2022
  65. www.sciencedirect.com www.sciencedirect.com
    WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy
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    sciencedirect.com/science/article/pii/S1097276522002659
  66. Mar 2022
  67. www.sciencedirect.com www.sciencedirect.com
    Counteractive and cooperative actions of muscle β-catenin and CaV1.1 during early neuromuscular synapse formation
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    sciencedirect.com/science/article/pii/S2589004222002954
  68. Feb 2022
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bidirectional Crosstalk between MAOA and AR Promotes Hormone-Dependent and Castration-Resistant Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8373824/
  70. Jan 2022
  71. www.sciencedirect.com www.sciencedirect.com
    Multi-omic analysis reveals divergent molecular events in scarring and regenerative wound healing
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    sciencedirect.com/science/article/pii/S1934590921005257
  72. Oct 2021
  73. www.sciencedirect.com www.sciencedirect.com
    Lentiviral-mediated ectopic expression of YAP and TAZ in YAPoff cancer cell lines
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    sciencedirect.com/science/article/pii/S2666166721005761
  74. Aug 2021
  75. www.sciencedirect.com www.sciencedirect.com
    Induced phase separation of mutant NF2 imprisons the cGAS-STING machinery to abrogate antitumor immunity
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    sciencedirect.com/science/article/pii/S1097276521006249
  76. www.sciencedirect.com www.sciencedirect.com
    Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis
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    sciencedirect.com/science/article/pii/S2211124721010342
  77. www.sciencedirect.com www.sciencedirect.com
    Genetically variant human pluripotent stem cells selectively eliminate wild-type counterparts through YAP-mediated cell competition
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    sciencedirect.com/science/article/pii/S153458072100602X
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of response signatures for tankyrase inhibitor treatment in tumor cell lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC8313754/
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6345631/
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  82. Jul 2021
  83. www.sciencedirect.com www.sciencedirect.com
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  84. dev.biologists.org dev.biologists.org
    Yap and its subcellular localization have distinct compartment-specific roles in the developing lung
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    dev.biologists.org/content/146/9/dev175810
  85. elifesciences.org elifesciences.org
    Transitions in cell potency during early mouse development are driven by Notch
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    elifesciences.org/articles/42930
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC5360446/
  87. www.sciencedirect.com www.sciencedirect.com
    Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity
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    sciencedirect.com/science/article/pii/S153561082100338X
  88. Jun 2021
  89. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    TNIK is a therapeutic target in Lung Squamous Cell Carcinoma and regulates FAK activation through Merlin.
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    cancerdiscovery.aacrjournals.org/content/11/6/1411
  90. May 2021
  91. www.sciencedirect.com www.sciencedirect.com
    Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation
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    sciencedirect.com/science/article/pii/S1534580720303506
  92. Apr 2021
  93. www.sciencedirect.com www.sciencedirect.com
    Cell intercalation driven by SMAD3 underlies secondary neural tube formation
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  94. www.sciencedirect.com www.sciencedirect.com
    Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer
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    sciencedirect.com/science/article/pii/S1535610820302695
  95. Mar 2021
  96. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    The tumor suppressor LATS2 reduces v‐Src‐induced membrane blebs in a kinase activity‐independent manner
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202001909R
  97. Feb 2021
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporal control of phosphatidic acid signaling with optogenetic, engineered phospholipase Ds
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    ncbi.nlm.nih.gov/pmc/articles/PMC7054994/
  99. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Suppression of adipocyte differentiation by low‐intensity pulsed ultrasound via inhibition of insulin signaling and promotion of CCN family protein 2
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    onlinelibrary.wiley.com/doi/10.1002/jcb.29680
  100. Sep 2020
  101. www.sciencedirect.com www.sciencedirect.com
    Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair
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    sciencedirect.com/science/article/pii/S2211124720308093
  102. www.sciencedirect.com www.sciencedirect.com
    Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis
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  103. www.sciencedirect.com www.sciencedirect.com
    MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation
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    sciencedirect.com/science/article/pii/S221112472030841X
  104. www.sciencedirect.com www.sciencedirect.com
    Osmotic Gradients in Epithelial Acini Increase Mechanical Tension across E-cadherin, Drive Morphogenesis, and Maintain Homeostasis
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    sciencedirect.com/science/article/pii/S0960982219316203
  105. www.nature.com www.nature.com
    Centrosome anchoring regulates progenitor properties and cortical formation
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    nature.com/articles/s41586-020-2139-6
  106. www.nature.com www.nature.com
    Syndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway
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    nature.com/articles/s41563-019-0567-1
  107. www.sciencedirect.com www.sciencedirect.com
    YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow
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    sciencedirect.com/science/article/pii/S1534580720300071
  108. Jan 2020
  109. www.sciencedirect.com www.sciencedirect.com
    Truncated BRPF1 Cooperates with Smoothened to Promote Adult Shh Medulloblastoma
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    sciencedirect.com/science/article/pii/S2211124719315281
  110. www.sciencedirect.com www.sciencedirect.com
    Maintenance of Primary Hepatocyte Functions In Vitro by Inhibiting Mechanical Tension-Induced YAP Activation
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    sciencedirect.com/science/article/pii/S2211124719314615
  111. www.sciencedirect.com www.sciencedirect.com
    The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes
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    sciencedirect.com/science/article/pii/S2211124719307004
  112. www.sciencedirect.com www.sciencedirect.com
    Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures
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  113. www.sciencedirect.com www.sciencedirect.com
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    The Hippo Pathway Blocks Mammalian Retinal Müller Glial Cell Reprogramming
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    sciencedirect.com/science/article/pii/S2211124719305121
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  119. Nov 2018
  120. www.sciencedirect.com www.sciencedirect.com
    Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    The Legionella Effector Kinase LegK7 Hijacks the Host Hippo Pathway to Promote Infection
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    sciencedirect.com/science/article/pii/S1931312818304323
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma
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  125. www.sciencedirect.com www.sciencedirect.com
    Quantitative Analysis Reveals that Actin and Src-Family Kinases Regulate Nuclear YAP1 and Its Export
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  127. Nov 2017
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    Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance
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