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TCR origin and specificity to environmental or self-antigens on distinct antigen-presenting cells determine peripheral Treg cell differentiation

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  DOI: 10.1016/j.immuni.2026.07.001
  
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sciencedirect.com/science/article/pii/S1074761326002773
May 2026
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Activating an interleukin 4-FLT3-STAT6 axis in multipotent progenitors restores lymphopoiesis in inflammation and aging

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sciencedirect.com/science/article/pii/S1074761326001809
Apr 2026
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STAT5 activation enhances adoptive therapy combined with peptide vaccination by preventing PD-1 inhibition

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aacrjournals.org/mct/article/24/3/419/752080/STAT5-Activation-Enhances-Adoptive-Therapy
Mar 2026
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Foxp3 and BATF cooperatively direct cis-regulatory programs and gene expression for effector Treg cell differentiation

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A hierarchical Rorc(γt) cis-regulatory cascade orchestrates differentiation of RORγt⁺ innate immune cells

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1-s2.0-S2589004226008114-main-html.html

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Hematopoietic stem cells activate a latent differentiation pathway to facilitate recovery after 5-fluorouracil-induced myeloablation

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sciencedirect.com/science/article/pii/S1534580726000432
Feb 2026
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Heterogeneity and plasticity of the naive CD4+ T cell compartment

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  DOI: 10.1016/j.celrep.2026.116980
  
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sciencedirect.com/science/article/pii/S2211124726000586
Dec 2025
54.241.53.176 54.241.53.176

2025.12.04.692214v1.full-html.html

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54.241.53.176/5fc200e8d22c6941d9a65233a02e8f8a1a806803/2025.12.04.692214v1.full-html.html
Aug 2025
52.53.155.43 52.53.155.43

2025.08.13.669552v1.full-html.html

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52.53.155.43/cbef6d49734833e21d46745b8a2764b4c745ed76/2025.08.13.669552v1.full-html.html
May 2025
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RAG suppresses group 2 innate lymphoid cells

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  DOI: 10.7554/eLife.98287
  
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Serotonin transporter inhibits antitumor immunity through regulating the intratumoral serotonin axis

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Macrophages direct location-dependent recall of B cell memory to vaccination

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  DOI: 10.1016/j.cell.2025.04.005
  
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Apr 2025
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PPARγ-dependent remodeling of translational machinery in adipose progenitors is impaired in obesity

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pmc.ncbi.nlm.nih.gov/articles/PMC12002411/
Jan 2025
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Splenic fibroblasts control marginal zone B cell movement and function via two distinct Notch2-dependent regulatory programs

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  DOI: 10.1016/j.immuni.2024.12.003
  
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sciencedirect.com/science/article/pii/S1074761324005673
Oct 2024
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A Prime-Boost Vaccination Approach Induces Lung Resident Memory CD8+ T Cells Derived from Central Memory T Cells That Prevent Tumor Lung Metastasis

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  DOI: 10.1158/0008-5472.CAN-23-3257
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11443216/
Aug 2024
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The amalgam of naive CD4+ T cell transcriptional states is reconfigured by helminth infection to dampen the amplitude of the immune response

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cell.com/immunity/fulltext/S1074-7613(24)00355-8
Apr 2024
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Cbl-b mitigates the responsiveness of naive CD8+ T cells that experience extensive tonic T cell receptor signaling

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  DOI: 10.1126/scisignal.adh0439
  
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science.org/doi/10.1126/scisignal.adh0439
Mar 2024
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A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate

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  DOI: 10.1016/j.stem.2024.02.004
  
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Dec 2023
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Central glucagon-like peptide 1 receptor activation inhibits Toll-like receptor agonist-induced inflammation

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Sep 2023
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ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m6A modification-mediated RNA stability control

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Jul 2023
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A genetic method specifically delineates Th1-type Treg cells and their roles in tumor immunity

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sciencedirect.com/science/article/pii/S2211124723008240
Apr 2023
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T helper 1 effector memory CD4+ T cells protect the skin from poxvirus infection

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Mar 2023
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Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment

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Feb 2023
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Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells

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Jan 2023
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Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22

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Sep 2022
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Profiling of Tregs across tissues reveals plasticity in ST2 expression and hierarchies in tissue-specific phenotypes

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  DOI: 10.1016/j.isci.2022.104998
  
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Aug 2022
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Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism, microbiota, and T cell-induced inflammation

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May 2022
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Aryl hydrocarbon receptor signals in epithelial cells govern the recruitment and location of Helios+ Tregs in the gut

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Apr 2022
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TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells

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  DOI: 10.1016/j.celrep.2022.110657
  
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Jan 2022
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Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function

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  DOI: 10.1016/j.immuni.2021.12.001
  
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Nov 2021
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6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function

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1. scibot 05 Nov 2021
  
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  DOI: 10.7554/eLife.67476
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8553335/
Oct 2021
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Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis

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  DOI: 10.1016/j.celrep.2021.109887
  
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sciencedirect.com/science/article/pii/S2211124721013577
Aug 2021
europepmc.org europepmc.org

Untitled document

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  DOI: 10.7554/eLife.41258
  
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europepmc.org/articles/PMC6298771/
May 2021
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Resident memory T cells in tumor-distant tissues fortify against metastasis formation

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  DOI: 10.1016/j.celrep.2021.109118
  
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Positive selection of IgG+ over IgM+ B cells in the germinal center reaction

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1. scibot 15 Apr 2021
  
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  RRID:AB_1186098
  
  DOI: 10.1016/j.immuni.2021.03.013
  
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Blockade of 6-phosphogluconate dehydrogenase generates CD8+ effector T cells with enhanced anti-tumor function

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1. scibot 10 Mar 2021
  
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  DOI: 10.1016/j.celrep.2021.108831
  
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Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging

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  DOI: 10.7554/eLife.41258
  
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Quorum Regulation via Nested Antagonistic Feedback Circuits Mediated by the Receptors CD28 and CTLA-4 Confers Robustness to T Cell Population Dynamics

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1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.immuni.2020.01.018
  
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Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways

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1. scibot 16 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.03.019
  
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Untitled document

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  DOI: 10.1016/j.immuni.2018.12.014
  
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Untitled document

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  DOI: 10.7554/eLife.41258
  
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Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging

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  DOI: 10.1016/j.celrep.2018.12.101
  
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Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination

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T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells

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Tolerogenic Nanoparticles Induce Antigen-Specific Regulatory T Cells and Provide Therapeutic Efficacy and Transferrable Tolerance against Experimental Autoimmune Encephalomyelitis

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CCR6 Defines Memory B Cell Precursors in Mouse and Human Germinal Centers, Revealing Light-Zone Location and Predominant Low Antigen Affinity

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Granulocyte-Monocyte Progenitors and Monocyte-Dendritic Cell Progenitors Independently Produce Functionally Distinct Monocytes

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Nov 2017
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Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells

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1. scibot 08 Nov 2017
  
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