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TRRAP enables MMB-dependent mitotic transcription and determines sensitivity to CHK1 inhibition

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1. scibot 23 Sep 2026
  
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  RRID:AB_1209417
  
  DOI: 10.1016/j.celrep.2026.117985
  
  Resource: (Abcam Cat# ab70369, RRID:AB_1209417)
  
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sciencedirect.com/science/article/pii/S2211124726010636
Jul 2025
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KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer

1
1. scibot 15 Jul 2025
  
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  AB_1209417
  
  DOI: 10.1016/j.ccell.2025.06.011
  
  Resource: (Abcam Cat# ab70369, RRID:AB_1209417)
  
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sciencedirect.com/science/article/pii/S1535610825002612
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

DNA-PK Inhibition Shows Differential Radiosensitization in Orthotopic GBM PDX Models Based on DDR Pathway Deficits

1
1. scibot 11 Jun 2025
  
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  RRID:AB_1209417
  
  DOI: 10.1158/1535-7163.MCT-24-0003
  
  Resource: (Abcam Cat# ab70369, RRID:AB_1209417)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12014860/
Aug 2024
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RTEL1 helicase counteracts RAD51-mediated homologous recombination and fork reversal to safeguard replicating genomes

1
1. scibot 20 Aug 2024
  
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  AB_1209417
  
  DOI: 10.1016/j.celrep.2024.114594
  
  Resource: (Abcam Cat# ab70369, RRID:AB_1209417)
  
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sciencedirect.com/science/article/pii/S2211124724009239
Feb 2024
aacrjournals.org aacrjournals.org

A Phase 1 Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-Dose Gemcitabine in Metastatic Pancreatic Adenocarcinoma Patients

1
1. scibot 24 Feb 2024
  
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  RRID:AB_1209417
  
  DOI: 10.1158/1078-0432.CCR-23-2005
  
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aacrjournals.org/clincancerres/article/29/24/5047/731678/A-Phase-I-Expansion-Cohort-Study-Evaluating-the
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PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma

1
1. scibot 21 Feb 2024
  
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  RRID:AB_1209417
  
  DOI: 10.1038/s41467-024-45760-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10873513/
Dec 2023
52.53.155.43 52.53.155.43

ccr-23-2005-html.html

1
1. scibot 01 Dec 2023
  
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  AB_1209417
  
  DOI: 10.1158/1078-0432.ccr-23-2005
  
  Resource: (Abcam Cat# ab70369, RRID:AB_1209417)
  
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52.53.155.43/8373d350712629607ae5ff64c6434e7646ebbbe9/ccr-23-2005-html.html
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Drug–gene Interaction Screens Coupled to Tumor Data Analyses Identify the Most Clinically Relevant Cancer Vulnerabilities Driving Sensitivity to PARP Inhibition

1
1. scibot 29 Mar 2023
  
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  RRID:AB_1209417
  
  DOI: 10.1158/2767-9764.CRC-22-0119
  
  Resource: (Abcam Cat# ab70369, RRID:AB_1209417)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10035383/
Apr 2022
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H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ

1
1. scibot 21 Apr 2022
  
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  RRID:AB_1209417
  
  DOI: 10.1016/j.molcel.2022.03.030
  
  Resource: (Abcam Cat# ab70369, RRID:AB_1209417)
  
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sciencedirect.com/science/article/pii/S1097276522002684
Dec 2021
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The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability

1
1. scibot 09 Dec 2021
  
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  RRID:AB_1209417
  
  DOI: 10.1016/j.celrep.2021.110080
  
  Resource: (Abcam Cat# ab70369, RRID:AB_1209417)
  
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sciencedirect.com/science/article/pii/S2211124721015710
Nov 2021
www.cell.com www.cell.com

MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts

1
1. scibot 30 Nov 2021
  
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  RRID:AB_1209417
  
  DOI: 10.1016/j.molcel.2021.11.002
  
  Resource: (Abcam Cat# ab70369, RRID:AB_1209417)
  
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cell.com/molecular-cell/fulltext/S1097-2765(21)00952-7
May 2021
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Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters

1
1. scibot 08 May 2021
  
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  RRID:AB_1209417
  
  DOI: 10.1016/j.molcel.2020.12.035
  
  Resource: (Abcam Cat# ab70369, RRID:AB_1209417)
  
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  SciCrunch record: RRID:AB_1209417
  
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sciencedirect.com/science/article/pii/S1097276520309564
Feb 2021
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A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability

1
1. scibot 24 Feb 2021
  
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  RRID:AB_1209417
  
  DOI: 10.1016/j.celrep.2020.01.020
  
  Resource: (Abcam Cat# ab70369, RRID:AB_1209417)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1209417
  
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sciencedirect.com/science/article/pii/S2211124720300292
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AMPK-mediated phosphorylation on 53BP1 promotes c-NHEJ

1
1. scibot 24 Feb 2021
  
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  RRID:AB_1209417
  
  DOI: 10.1016/j.celrep.2021.108713
  
  Resource: (Abcam Cat# ab70369, RRID:AB_1209417)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_1209417
  
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  RRIDCUR:Validated RRID:AB_1209417
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RRID:AB_1209417

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sciencedirect.com/science/article/pii/S2211124721000267
Oct 2020
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MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia

1
1. scibot 01 Oct 2020
  
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  RRID:AB_1209417
  
  DOI: 10.1016/j.stem.2020.09.004
  
  Resource: (Abcam Cat# ab70369, RRID:AB_1209417)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_1209417
  
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  RRIDCUR:Validated RRID:AB_1209417
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sciencedirect.com/science/article/pii/S1934590920304501
Sep 2020
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A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability

1
1. scibot 09 Sep 2020
  
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  RRID:AB_1209417
  
  DOI: 10.1016/j.celrep.2020.01.020
  
  Resource: (Abcam Cat# ab70369, RRID:AB_1209417)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_1209417
  
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  RRIDCUR:Validated RRID:AB_1209417
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sciencedirect.com/science/article/pii/S2211124720300292
Jan 2020
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ATR Signaling Uncouples the Role of RAD51 Paralogs in Homologous Recombination and Replication Stress Response

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1209417
  
  DOI: 10.1016/j.celrep.2019.09.008
  
  Resource: (Abcam Cat# ab70369, RRID:AB_1209417)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_1209417
  
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  RRID:AB_1209417 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719311854
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Untitled document

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1209417
  
  DOI: 10.1016/j.molcel.2018.11.036
  
  Resource: (Abcam Cat# ab70369, RRID:AB_1209417)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_1209417
  
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  RRID:AB_1209417 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276518310062